De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
Kirov, G, Pocklington, A J, Holmans, P, Ivanov, D, Ikeda, M, Ruderfer, D, Moran, J, Chambert, K +22 more·2012·Molecular Psychiatry
Cited by (879)
Items 801–879 of 879
- Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for SchizophreniaMark Ainsley Colijn · 2025 · Journal of Intellectual Disability Research
- The function of TCF4 in Pitt-Hopkins syndrome and schizophreniaMarc P. Forrest · 2013 · ORCA Online Research @Cardiff (Cardiff University)
- The systemic effects of glutamatergic dysfunction in schizophrenia: from receptors to networksLauren K Hayrynen Schaeffer · 2017
- Cognition, psychopathology and the role of genetic variation in Catechol-O-Methyltransferase in children at increased risk of schizophreniaMaria Niarchou · 2013 · ORCA Online Research @Cardiff (Cardiff University)
- A Thalamocortical Cell-Adhesion Code Primes Sensory Cortical SpecificationTeresa Guillamón-Vivancos, Lorenzo Puche-Aroca, L. Wang, I. Fuentes-Jurado, Dorien Vandael, D. Torres, Mar Aníbal-Martínez, Francisco J. Martini, Guillermina López‐Bendito · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Proteomics of SchizophreniaMarcelo P. Coba · 2016 · Elsevier eBooks
- Reviewer #2 (Public Review): Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex functionMastwal Surjeet, Li Xinjian, Stowell Rianne · 2023 · eLife
- Denying Genetic CausalityKaren G. Hales · 2013 · CBE—Life Sciences Education
- Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiencyBrittany A. Davis, François David, Ciara O’Regan · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Towards personalized medicine in psychiatry : focus on suicideDaniel F. Levey · 2016 · IUScholarWorks (Indiana University)
- The Association of Hippocampal Long-Term Potentiation-Induced Gene Expression with Genetic Risk for PsychosisNatalie Wellard, Nicholas E. Clifton, Elliott Rees, Kerrie L. Thomas, Jérémy Hall · 2024 · International Journal of Molecular Sciences
- Sporadiese skisofrenieJohannes Lodewikus Roos · 2019
- Geïsoleerde populasiesJohannes Lodewikus Roos · 2019
- Lo que un psiquiatra necesita saber sobre variaciones en el número de copias [translation of “What a psychiatrist needs to know about copy number variants” by Rodolfo Zaratiegui]George Kirov, Elliott Rees, James Walters · 2015 · BJPsych Advances
- Copy Number Variations and Neuropsychiatric DiseasesNey Alliey‐Rodriguez, Elliot S. Gershon · 2014 · Encyclopedia of Life Sciences
- Noise-robust assessment of SNP array based CNV calls through local noise estimation of log R ratiosNele Cosemans, Peter D. Claes, Nathalie Brison, Joris Robert Vermeesch, Hilde Peeters · 2018 · Statistical Applications in Genetics and Molecular Biology
- Manuscript Word Count: Abstract: 193; Text, with citations, without references: 3921 Number of Tables: 2; Supplemental Files: Yes Whole-genome sequencing suggests schizophrenia risk mechanisms in humans with 22q11.2 deletion syndromeDaniele Merico, Mehdi Zarrei, Gregory Costain, Lucas Ogura, Babak Alipanahi, Nancy J. Butcher, Bhooma Thiruvahindrapuram, Eva W.C. Chow, Danielle Molinari Andrade, Brendan J. Frey et al. · 2015
- Complex neurodevelopmental disorders associated with 16p11.2 duplication: a case reportMarco O. Bertelli, Annamaria Bianco, Michele Rossi, Maria Stella Vescio · 2026 · Advances in Mental Health and Intellectual Disabilities
- Kliniese kenmerke van Afrikaner-skisofreniepasiënteJohannes Lodewikus Roos · 2019 · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie
- Molecular pathology in neuropsychiatric disordersGeorge Kirov, Elliott Rees · 2019 · Elsevier eBooks
- Disfunções neurológicas e declínio cognitivoValdemiro Carlos Sgarbieri, Maria Teresa Bertoldo Pacheco, Nádia Fátima Gibrim, Denise Aparecida Gonçalves de Oliveira, Maria Elisa Caetano‐Silva · 2021 · Editora da Unicamp eBooks
- Phase Separation of a Novel form of Euchromatic Histone Methyltransferasel (EHMT1 N/C ) into cytoplasmic RNA viral Inclusion bodies facilitates their coalescence, thereby enhancing viral replicationKriti Kestur Biligiri, Nishi Raj Sharma, Abhishek Mohanty, Debi Prasad Sarkar, Praveen Kumar Vemula, Shravanti Rampalli · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- The Mind and its Nucleosomes – Chromatin (dys)Regulation in Major Psychiatric DiseaseRahul A. Bharadwaj, Cyril Jayakumar Peter, Schahram Akbarian · 2013 · Elsevier eBooks
- Familiële skisofrenieJohannes Lodewikus Roos · 2019
- Metabolic effects of the schizophrenia-associated 3q29 deletion are sex-specific and uncoupled from behavioral phenotypesRebecca M. Pollak, Ryan H. Purcell, Timothy P. Rutkowski, Tamika Malone, Kimberly J. Pachura, Gary Jonathan Bassell, Michael P. Epstein, Paul A. Dawson, Matthew Ryan Smith, Dean P. Jones et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Genome-scale copy number variant analysis in schizophrenia patients and controls from South IndiaMinali Singh, Dibyabhabha Pradhan, Poornima Kkani, Gundugurti Prasad Rao, Naveen Kumar Dhagudu, Lov Kumar, Chellamuthu Ramasubramanian, Srinivasan Ganesh Kumar, Surekha Sonttineni, Kommu Naga Mohan · 2023 · Frontiers in Molecular Neuroscience
- Calciopathies and Neuropsychic Disorders: Physiological and Genetic AspectsNatalia A. Dyuzhikova, M. B. Pavlova · 2023 · Успехи физиологических наук
- A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk scoreDavid Curtis · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Vroeë afwykende niepsigotiese gedrag in skisofrenieJohannes Lodewikus Roos · 2019 · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie
- Synaptic Mechanisms of Psychotic DisordersSeth G. N. Grant · 2017
- Dysregulation of NRSF/REST via EHMT1 is associated with psychiatric disordersMouhamed Alsaqati, Brittany A. Davis, Jamie Wood, Megan Jones, Lora Jones, Aishah Westwood, Olena Petter, Anthony R Isles, David E.J. Linden, Marianne B. M. van den Bree et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Fos/AP-1 as an Exemplar for the Study of Neuronal Activity-Dependent Gene RegulationEric C. Griffith, Michael E. Greenberg · 2024 · Springer eBooks
- Perturbations of a causal synaptic molecular network in autism and schizophrenia revealed with multiplexed imagingReuven Falkovich, Eric Danielson, Karen Perez de Arce, Eike‐Christian Wamhoff, Jeffrey R. Cottrell, Morgan Sheng, Mark Bathe · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Altered resting-state functional connectivity in hiPSC-derived neuronal networks from schizophrenia patientsSofía Puvogel, Kris Blanchard, Bárbara S. Casas · 2021 · medRxiv
- Role of cryptic rearrangements of human chromosomes in the aetiology of schizophreniaLivia Jurisova, Roman Šolc · 2023 · Journal of Genetics
- Seguimiento del Desarrollo Psicomotor en un Caso con Microdeleción Distal 1q21.1Ana Isabel Cañada Ruiz · 2016 · Revista de Discapacidad Clínica y Neurociencias
- Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disordersSanders, B., Daniel D’Andrea, Mark O. Collins, Elliott Rees, Tom G. J. Steward, Yongchang Zhu, Gareth Chapman, Sophie E. Legge, Antonio F. Pardiñas, Adrian J. Harwood et al. · 2020 · White Rose Research Online (University of Leeds, The University of Sheffield, University of York)
- Targeting Epigenetic Enzymes for Treatment of Autism Spectrum DisordersZhen Yan · 2024 · Springer eBooks
- The Relationship Between Neuromelanin, Glutamate, and GABA in First-Episode Psychosis: A Multimodal Magnetic Resonance Imaging StudyFrancisco Reyes-Madrigal, Pablo León-Ortíz, Kenneth Wengler, Helena P. Bachmann, Nicholas M. Singletary, María Ortuño, Xiangling Mao, Luis F. Rivera-Chávez, Melanie Malacara, Dikoma C. Shungu et al. · 2025 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of SchizophreniaBRIAN J. MORRIS · 2026 · Molecular Neurobiology
- PSD-95 drives binocular vision maturation critical for predationSubhodeep Bhattacharya, Livia J.F. Wilod Versprille, Cornelia Schöne, Oliver M. Schlüter, Siegrid Löwel · 2026 · eLife
- A Comprehensive Review of the Application of Time-Frequency Analysis in Screening for Cognitive Impairment in Schizophrenia添怡 罗 · 2024 · Advances in Psychology
- Peer Review #1 of "Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study (v0.2)"2020 · PeerJ
- Targeted Sequencing and Integrative Analysis to Prioritise Candidate Genes in Neurodevelopmental DisordersYi Zhang, Tao Wang, Yan Wang · 2021 · Research Square
- SchizophreniaAiden Peter Corvin · 2016 · Elsevier eBooks
- Author Response: Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex functionSurjeet S. Mastwal, Xinjian Li, Rianne D. Stowell, Matthew T. C. Manion, Wenyu Zhang, Namshik Kim, Ki‐Jun Yoon, Hongjun Song, Guo‐li Ming, Kuan Hong Wang · 2023 · eLife
- Peer Review #2 of "Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study (v0.1)"2020 · PeerJ
- Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in miceYevheniia Ishchenko, Amanda T. Jeng, Shufang Feng, Timothy Nottoli, Cindy Manriquez-Rodriguez, Khanh K Nguyen, Melissa G Carrizales, Matthew J Vitarelli, Ellen E Corcoran, Charles A. Greer et al. · 2024 · eLife
- Calciopathies and Neuropsychiatric Disorders: Physiological and Genetic AspectsNatalia A. Dyuzhikova, M. B. Pavlova · 2023 · Neuroscience and Behavioral Physiology
- Faculty Opinions recommendation of Psychiatric disorders in children with 16p11.2 deletion and duplication.Santhosh Girirajan · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Illuminating cAMP dynamics at the synapse with multiphoton FLIM-FRET ImagingLucien West · 2016
- Oscillations neuronales et connectivité dans la schizophrénie : approches électro/magnéto-encéphalographiquesPeter J. Uhlhaas, Anne Giersch · 2018 · HAL
- Creativity and mental disorderGeorge Kirov, Geoffrey F. Miller · 2012 · The British Journal of Psychiatry
- Schizophrenia genomicsNiamh Ryan, Cathal Ormond, Philip Brady, Elizabeth A. Heron, Aiden Peter Corvin · 2022 · Elsevier eBooks
- Dysfunction of cAMP-PKA-calcium signaling axis in striatal medium spiny neurons: a role in schizophrenia and Huntington’s disease pathogenesisMarija Fjodorova, Zoe Noakes, Daniel Cabezas de la Fuente, Adam C. Errington, Meng Li · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Identifying the parent-of-origin of de novo SNVs in schizophreniaLaura Escudero Monreal · 2013 · RIUVic (UVic-UCC)
- PSD-95 drives binocular vision maturation critical for predationSubhodeep Bhattacharya, Livia J.F. Wilod Versprille, Jonathan Ho, Xiaojie Huang, Cornelia Schöne, Oliver M. Schlüter, Siegrid Löwel · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- NMDAR hypofunction increases top-down influence on sensory processingAdam Ranson, Eluned Broom, Anna L. Powell · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Reviewer #3 (Public Review): Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex functionMastwal Surjeet, Li Xinjian, Stowell Rianne · 2023 · eLife
- Genomic copy number variation in schizophreniaDanielle S. Rudd · 2014
- Joseph T. Coyle2018 · Society for Neuroscience eBooks
- Driver or passenger? A new assessment of genes in the schizophrenia-associated 3q29 deletion locus for contribution to neurodevelopmental disordersAllyson R. Herriges, Ryan H. Purcell · 2026 · Journal of Neurodevelopmental Disorders
- The role of DLG-MAGUKs in mediating signaling specificity at the postsynaptic densityJoana-Kristin Duda · 2019
- Snapshot of Schizophrenia: Current Knowledge and ProspectsRuixue Gao · 2021 · E3S Web of Conferences
- Convergence of schizophrenia risk genes on synaptic processes — Opportunities for neuroscienceJérémy Hall · 2014 · Schizophrenia Research
- Agtergrond as rigtingaanwyserJohannes Lodewikus Roos · 2019 · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie
- Genome-Wide and Rare Variant Association Studies of Amblyopia in Admixed American and African Ancestry GroupsKyoung A. Viola Lee, Mary C. Whitman · 2026 · Ophthalmology
- Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in miceYevheniia Ishchenko, Amanda T. Jeng, Shufang Feng, Timothy Nottoli, Cindy Manriquez-Rodriguez, Khanh K Nguyen, Melissa G Carrizales, Matthew J Vitarelli, Ellen E Corcoran, Charles A. Greer et al. · 2025 · eLife
- Additional file 1 of A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatumTaesun Yoo, Sun-Gyun Kim, Soo Hyun Yang, Hyun Kim, Eunjoon Kim, Soo Young Kim · 2020 · Figshare
- Identification of activity-induced Egr3 -dependent genes reveals genes associated with DNA damage response and schizophreniaKetan K. Marballi, Khaled Alganem, Samuel J. Brunwasser, Arhem Barkatullah, Kimberly T. Meyers, Janet M. Campbell, Robert R Mccullumsmith, Amelia L. Gallitano · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Association Tests Using Co py N umber Profile Cur ves (CONCUR) Enhances Power in Rare Copy Number Variant AnalysisAmanda Brucker, Wenbin Lu, Rachel Marceau West et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Genetic interaction of DISC1 and Neuroligin in regulation of glutamatergic synaptogenesisTakato Honda, Himani Pandey, Akira Sawa, Katsuo Furukubo-Tokunaga · 2026 · Frontiers in Neuroscience
- Genetic Architecture of Schizophrenia: From Common Variants to Rare Mutations and Clinical TranslationAmbreen Ilyas · 2026 · Premier Journal of Genetics
- VTA-forebrain connectivity moderates adaptive behaviorSadia Islam Sinza, Kwon Choi, Ignitius Ezekiel Lim, Madison Ashley Williams, Olalekan Michael Ogundele · 2026 · Brain Structure and Function
- Altered Resting-State Functional Connectivity in Hipsc-Derived Neuronal Networks from Schizophrenia PatientsSofía Puvogel, Kris Blanchard, Bárbara S. Casas, Robyn L. Miller, Delia Garrido, Stevens Kastrup Rehen, Magdalena Sanhueza, Verónica Palma · 2021 · SSRN Electronic Journal
- PSD-95 drives binocular vision maturation critical for predationSubhodeep Bhattacharya, Livia J.F. Wilod Versprille, Cornelia Schöne, Oliver M. Schlüter, Siegrid Löwel · 2026 · eLife
- Modelling Schizophrenia: Strategies for Identifying Improved Platforms for Drug DiscoveryJohn L. Waddington, Colm M. P. O’Tuathaigh · 2015 · Royal Society of Chemistry eBooks
- Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex functionSurjeet S. Mastwal, Xinjian Li, Rianne D. Stowell, Matthew T. C. Manion, Wenyu Zhang, Namshik Kim, Ki‐Jun Yoon, Hongjun Song, Guo‐li Ming, Kuan Hong Wang · 2023 · eLife
- Splicing of the SynGAP Carboxyl-Terminus Enables Isoform-Specific Tuning of NMDA Receptor Signaling Linked to Cognitive FunctionMurat Kılınç, Thomas K. Creson, Camilo Rojas, Sabyasachi Maity, Aliza A. Le, Julie C. Lauterborn, Brent Wilkinson, Nicolas G. Hartel, Nicholas Alexander Graham, Adrian M. Reich et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)