De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

Kirov, G, Pocklington, A J, Holmans, P, Ivanov, D, Ikeda, M, Ruderfer, D, Moran, J, Chambert, K +22 more·2012·Molecular Psychiatry

DOI 10.1038/mp.2011.154

Cited by (879)

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Drew, James, Arancibia-Carcamo, I. Lorena, Jolivet, Renaud, Lopez-Domenech, Guillermo, Attwell, David, Kittler, Josef T. · 2020
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Elodie Lacaze, Nicolas Gruchy, Marie‐José Penniello, Ghislaine Plessis, Nicolas Richard, Mathieu Decamp, Hervé Mittre, Nathalie Leporrier, Joris Andrieux, Marie‐Laure Kottler et al. · 2013 · American Journal of Medical Genetics Part A
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Jin Szatkiewicz, Menachem Fromer, Randal J. Nonneman, NaEshia Ancalade, Jessica Johnson, Eli A. Stahl, Elliott Rees, Sarah E. Bergen, Christina M. Hultman, George Kirov et al. · 2019 · Biological Psychiatry
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Jennifer K. Forsyth, Carrie E. Bearden · 2023 · American Journal of Psychiatry
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Martin H. Berryer, Gizem Rizki, Anna J. Nathanson, Jenny A. Klein, Darina Trendafilova, Sara G. Susco, Daisy Lam, Angelica Messana, Kristina M. Holton, Kyle W. Karhohs et al. · 2023 · eLife
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María Leonor Bustamante, Luisa Herrera, Pablo A. Gaspar, Rodrigo R. Nieto, Alejandro Maturana, María José Villar, Valeria Salinas, Hernán Silva I · 2017 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
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Neurobiologie der Schizophrenie
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Matthias Kirschner, Casey Paquola, Budhachandra S. Khundrakpam, Uku Vainik, Neha Bhutani, Benazir H. Hodzic-Santor, Foivos Georgiadis, Noor Al‐Sharif, Bratislav Mišić, Boris C. Bernhardt et al. · 2022 · Biological Psychiatry Global Open Science
Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders
Junping Ye, Zhanwang Huang, Qiyang Li, Zhongwei Li, Yuting Lan, Zhongju Wang, Chaoying Ni, Xiaohui Wu, Tingyun Jiang, Yujing Li et al. · 2023 · BMC Medicine
Inhibition of EHMT1/2 rescues synaptic damage and motor impairment in a PD mouse model
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A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia
Lynsey S. Hall, Christopher William Medway, Antonio F. Pardiñas · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity
Chia‐Shan Wu, Chris P. Jew, Hao Sun, Carlos J. Ballester‐Rosado, Hui‐Chen Lu · 2019 · Psychopharmacology
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Core transcriptional networks in Williams syndrome: IGF1-PI3K-AKT-mTOR, MAPK and actin signaling at the synapse echo autism
Li Dai, Robert B. Weiss, Diane Marie Dunn, Anna Ramirez, Sharan Paul, Julie R. Korenberg · 2021 · Human Molecular Genetics
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Yuyuan Wang, Shih-Hsin Hsu, Hsin-Yao Tsai · 2022 · International Journal of Molecular Sciences
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Anne-Clémence Priol, Laure Denis, Gaëlla Boulanger, Mathieu Thépaut, Marie‐Maude Geoffray, Sylvie Tordjman · 2021 · International Journal of Molecular Sciences
Somatic copy number variants in neuropsychiatric disorders
Eduardo A. Maury, Christopher A. Walsh · 2021 · Current Opinion in Genetics & Development
Evolutionary divergence in CTCF-mediated chromatin topology drives transcriptional innovation in humans
Xia Wu, Dan Xiong, Rong Liu, Xingqiang Lai, Yuhan Tian, Ziying Xie, Li Chen, Lanqi Hu, Jingjing Duan, Xinyu Gao et al. · 2025 · Nature Communications
Copy number variations (CNVs) in human pluripotent cell-derived neuroprogenitors
Nestor L. Lopez-Corrales, Kristin Mrasek, Martin Voigt, Thomas Liehr, Nadezda Kosyakova · 2012 · Gene
A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium
2016
NR3C1-mediated epigenetic regulation suppresses astrocytic immune responses in mice
Seongwan Park, Hyeonji Park, Youkyeong Gloria Byun, Xiaolin Wei, Junghyun Eom, Jaegeon Joo, Andrew Lee, Yarui Diao, Won‐Suk Chung, Inkyung Jung · 2025 · Nature Communications
A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging
Reuven Falkovich, Eric Danielson, Karen Perez de Arce, Eike‐Christian Wamhoff, Juliana Strother, Anna P. Lapteva, Morgan Sheng, Jeffrey R. Cottrell, Mark Bathe · 2023 · Cell Reports
Biological psychiatry: time for new paradigms
David E.J. Linden · 2013 · The British Journal of Psychiatry
Hippocampal Dysfunction in Schizophrenia and Aberrant Hippocampal Synaptic Plasticity in Rodent Model Psychosis: a Selective Review
Julia Bartsch, Björn Hendrik Schott, Joachim Behr · 2019 · Pharmacopsychiatry
Introduction to Epigenetics in Psychiatry
Richard S. Lee, Dimitrios Avramopoulos · 2014 · Elsevier eBooks
Copy Number Variations in Neuropsychiatric Disorders
Gergely Büki, Kinga Hadzsiev, Judit Bene · 2023 · International Journal of Molecular Sciences
Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese
Weihong Lu, Yi Zhang, Xinyu Fang, Weixing Fan, Wei Tang, Jun Cai, Lisheng Song, Chen Zhang · 2017 · Scientific Reports
Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development
Laura M. Huckins, Amanda L. Dobbyn, Douglas M. Ruderfer, Gabriel E. Hoffman, Weiqing Wang, Antonio F. Pardiñas, Veera Manikandan Rajagopal, Thomas D. Als, Hoang Nguyen, Kiran Girdhar et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells
Shafaqat Ali, Alexander Hoven, Regine J. Dress, Heiner Schaal, Judith Alferink, Stefanie Scheu · 2018 · BMC Genomics
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Tsung‐Ming Hu, Ying-Chieh Wang, Chia‐Liang Wu, Shih-Hsin Hsu, Hsin-Yao Tsai, Min-Chih Cheng · 2020 · Frontiers in Genetics
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
Douglas M. Ruderfer, Stephan Ripke, Andrew McQuillin, James Boocock, Eli A. Stahl, Jennifer M. Whitehead Pavlides, Niamh Mullins, Alexander W. Charney, Anil P. S. Ori, Loes M. Olde Loohuis et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
The nature of schizophrenia: As broad as it is long
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Andreas Sauer, Tineke Grent-‘t-Jong, Michael Wibral, Michael Grube, Wolf Singer, Peter J. Uhlhaas · 2020 · Frontiers in Psychiatry
Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Surjeet S. Mastwal, Xinjian Li, Rianne D. Stowell, Matthew T. C. Manion, Wenyu Zhang, Namshik Kim, Ki‐Jun Yoon, Hongjun Song, Guo‐li Ming, Kuan Hong Wang · 2023 · eLife
Haplotype Phasing and Inheritance of Copy Number Variants in Nuclear Families
Priit Palta, Lauris Kaplinski, Liina Nagirnaja, Andres Veidenberg, Märt Möls, Mari Nelis, Tõnu Esko, Andres Metspalu, Maris Laan, Maido Remm · 2015 · PLoS ONE
A kainate receptor GluK4 deletion, protective against bipolar disorder, is associated with enhanced cognitive performance across diagnoses in the TwinsUK cohort
Maria Koromina, Miles Flitton, Ian R. Mellor, Helen Miranda Knight · 2017 · The World Journal of Biological Psychiatry
Structural deviations of the posterior fossa and the cerebellum and their cognitive links in a neurodevelopmental deletion syndrome
Esra Sefik, Kuaikuai Duan, Yiheng Li, Brittney Sholar, Lindsey Evans, Jordan E. Pincus, Zeena Ammar, Melissa M. Murphy, Cheryl Klaiman, Celine A. Saulnier et al. · 2024 · Molecular Psychiatry
Psychopathology and cognitive performance in individuals with membrane-associated guanylate kinase mutations: a functional network phenotyping study
Kate Baker, Gaia Scerif, Duncan Edward Astle, Paul Charles Fletcher, Frances Lucy Raymond · 2015 · Journal of Neurodevelopmental Disorders
Schizophrenia Genetics: Building the Foundations of the Future
Katherine E. Tansey, Michael John Owen, Michael C. O’Donovan · 2014 · Schizophrenia Bulletin
14-3-3 Dysfunction in Dorsal Hippocampus CA1 (dCA1) Induces Psychomotor Behavior via a dCA1-Lateral Septum-Ventral Tegmental Area Pathway
Jiajing Zhang, Meaghan Navarrete, Yuying Wu, Yi Zhou · 2022 · Frontiers in Molecular Neuroscience
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Sonal Saxena, Poornima Kkani, Chellamuthu Ramasubramanian, Srinivasan Ganesh Kumar, Raghav Monisha, Gundugurti Prasad Rao, Kommu Naga Mohan · 2019 · Annals of Human Genetics
Visual cortical plasticity and the risk for psychosis: An interim analysis of the North American Prodrome Longitudinal Study
Michael Jacob, Brian J. Roach, Holly Hamilton, Ricardo E. Carrión, Ayşenil Belger, Erica Duncan, Jason Johannesen, Matcheri S. Keshavan, Sandra K. Loo, Margaret A. Niznikiewicz et al. · 2021 · Schizophrenia Research
A replication study of schizophrenia-related rare copy number variations in a Han Southern Chinese population
Jianmin Yuan, Jianlin Hu, Zhiqiang Li, Fuquan Zhang, Dexiang Zhou, Chunhui Jin · 2017 · Hereditas
Common variants in the ARC gene are not associated with cognitive abilities
Craig Myrum, Sudheer Giddaluru, Kaya K. Jacobsen, Thomas Espeseth, Lars H Nyberg, Astri Johansen Lundervold, Jan Haavik, Lars‐Göran Nilsson, Ivar Reinvang, Vidar M. Steen et al. · 2015 · Brain and Behavior
Enhancing DLG2 Implications in Neuropsychiatric Disorders: Analysis of a Cohort of Eight Patients with 11q14.1 Imbalances
Veronica Bertini, Roberta Milone, Paola Cristofani, Francesca Cambi, Chiara Bosetti, Filippo Barbieri, Silvano Bertelloni, Giovanni Cioni, Angelo Valetto, Roberta Battini · 2022 · Genes
Identification of rare variants in KCTD13 at the schizophrenia risk locus 16p11.2
Franziska Degenhardt, Barbara Heinemann, Jana Strohmaier, Marvin A. Pfohl, Ina Giegling, Andrea Hofmann, Kerstin U. Ludwig, Stephanie H. Witt, Michael Ludwig, Andreas J. Forstner et al. · 2016 · Psychiatric Genetics
Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiency
Brittany A. Davis, François David, Ciara O’Regan, Manal A. Adam, Adrian J. Harwood, Vincenzo Crunelli, Anthony R Isles · 2020 · Brain and Neuroscience Advances
Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling
Dick Schijven, Daniel Kofink, Vinicius Tragante · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Metabolic effects of the schizophrenia-associated 3q29 deletion
Rebecca M. Pollak, Ryan H. Purcell, Timothy P. Rutkowski, Tamika Malone, Kimberly J. Pachura, Gary Jonathan Bassell, Michael P. Epstein, Paul A. Dawson, Matthew Ryan Smith, Dean P. Jones et al. · 2022 · Translational Psychiatry
Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis
Amanda Brucker, Wenbin Lu, Rachel Marceau West, Qi-You Yu, Chuhsing Kate Hsiao, Tzu-Hung Hsiao, Ching‐Heng Lin, Patrik K. E. Magnusson, Patrick F. Sullivan, Jin Szatkiewicz et al. · 2020 · PLoS Computational Biology
A mild impairment in reversal learning in a bowl‐digging substrate deterministic task but not other cognitive tests in the Dlg2+/− rat model of genetic risk for psychiatric disorder
Simonas Griesius, Sophie Waldron, Katie Kamenish, Nick Cherbanich, Lawrence S. Wilkinson, Kerrie L. Thomas, Jérémy Hall, Jack R. Mellor, Dominic Michael Dwyer, Emma S. J. Robinson · 2023 · Genes Brain & Behavior
Validation of a microRNA target site polymorphism in H3F3B that is potentially associated with a broad schizophrenia phenotype
William Manley, Michael Moreau, Marco A. Azaro, Stephen K. Siecinski, Gillian Davis, Steven G. Buyske, Veronica J. Vieland, Anne S. Bassett, Linda M. Brzustowicz · 2018 · PLoS ONE
Downregulation by CNNM2 of ATP5MD Expression in the 10q24.32 Schizophrenia-Associated Locus Involved in Impaired ATP Production and Neurodevelopment
Zhongju Wang, Yongchang Zhu, Linyan Ye, Qiyang Li, Bo Guo, Hao Zhao, Xiuqin Bao, Qiqi Zhuo, Tengfei Yang, Zhaoqiang Li et al. · 2020 · Schizophrenia
Rare damaging variants in DNA repair and cell cycle pathways are associated with hippocampal and cognitive dysfunction: a combined genetic imaging study in first-episode treatment-naive patients with schizophrenia
Zhenxing Yang, M Li, X Hu, Bo Xiang, Wei Deng, Qingyuan Wang, Yunbing Wang, Liansheng Zhao, Xiaohong Ma, Pak Chung Sham et al. · 2017 · Translational Psychiatry
Psychosis and autism without functional regression in a patient with Kleefstra syndrome
Mark Ainsley Colijn, Cherelyn M. Lakusta, Julien L. Marcadier · 2022 · Psychiatric Genetics
Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets
David Curtis · 2018 · Psychiatric Genetics
Neuropsychological and Structural Neuroimaging Endophenotypes in Schizophrenia
William S. Stone, Larry J. Seidman · 2016 · Wiley eBooks
Genetic risk for schizophrenia is associated with altered visually-induced gamma band activity: evidence from a population sample stratified polygenic risk
Stavros I. Dimitriadis, Gavin Perry, Sonya F. Foley, Katherine E. Tansey, Derek Kenton Jones, Peter Holmans, Stanley Zammit, Jérémy Hall, Michael C. O’Donovan, Michael John Owen et al. · 2021 · Translational Psychiatry
A Deficiency of the Psychiatric Risk Gene DLG2/PSD-93 Causes Excitatory Synaptic Deficits in the Dorsolateral Striatum
Taesun Yoo, Shambhu Dutta Joshi, Sanjaya Prajapati, Yi Sul Cho, Jin-Kyeong Kim, Pil‐Hoon Park, Yong Chul Bae, Eunjoon Kim, Soo Young Kim · 2022 · Frontiers in Molecular Neuroscience
Genetics: Unravelling complexity
Jessica R. Wright · 2014 · Nature
Synaptic and Non‐Synaptic Functions of PTPRD : A Receptor Tyrosine Phosphatase at the Crossroads of Neural Circuitry and Metabolism
Seoyeong Kim, Jae Jin Shin, Muwon Kang, Yunho Yi, Eunjoon Kim · 2025 · Journal of Neurochemistry
Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Surjeet S. Mastwal, Xinjian Li, Rianne D. Stowell, Matthew T. C. Manion, Wenyu Zhang, Namshik Kim, Ki‐Jun Yoon, Hongjun Song, Guo‐li Ming, Kuan Hong Wang · 2023 · eLife
The autism-associated gene SYNGAP1 regulates human cortical neurogenesis
Marcella Birtele, Ashley Del Dosso, Tiantian Xu, Tuan N. Nguyen, Brent Wilkinson, Negar Hosseini, Sarah C. Nguyen, Jean‐Paul Urenda, Gavin T. Knight, Camilo Rojas et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics
Max Lam, Chen Chia-Yen, Xia Yan, William David Hill, Joey W. Trampush, Jin Yu, Emma Knowles, Gail Davies, Eli A. Stahl, Laura M. Huckins et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Pathway-Based Polygenic Risk Scores for Schizophrenia and Associations With Reported Psychotic-like Experiences and Neuroimaging Phenotypes in the UK Biobank
Miruna C. Barbu, Maria Viejo-Romero, Gladi Thng, Mark J. Adams, Katie F. M. Marwick, Seth G. N. Grant, Andrew Mark McIntosh, Stephen M. Lawrie, Heather Clare Whalley · 2023 · Biological Psychiatry Global Open Science