Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression

Lin, P-Y, Mischoulon, D, Freeman, M P, Matsuoka, Y, Hibbeln, J, Belmaker, R H, Su, K-P·2012·Molecular Psychiatry
DOI 10.1038/mp.2012.111

Cited by (145)

Items 101–145 of 145

  1. Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
    Hengying Chen, Jue Wang, Baohua Zheng, Wenqi Xia, Gongjun Tan, Hongyuan Wu, Yao Wang, Zhen Deng, Yiyuan Wang, Jianduan Zhang et al. · 2024 · Lipids in Health and Disease
  2. Change in fatty acid composition and evaluation of lipids and protein oxidation in the commercial cooked clams (Ruditapes decussatus)
    Safa Bejaoui, Imen Rabeh, Feriel Ghribi, Fatma Aouini, Imene Chetoui, Khaoula Telahigue, Nejla Soudani, M’hamed El Cafsi · 2019 · Grasas y Aceites
  3. Linking Omega-3 Fatty Acids and Depression
    Justyna Godos, Sabrina Castellano, Fabio Galvano, Giuseppe Grosso · 2019 · Elsevier eBooks
  4. Effect of Supplemental Enteral Fish Oil on the Development of Psychological Complications in Critically Ill Multiple‐Trauma Patients: 6 Months’ Follow‐Up
    Ilya Kagan, Ronit Mesilati‐Stahy, Pnina Green, Pierre Singer · 2020 · Journal of Parenteral and Enteral Nutrition
  5. Association between eicosapentaenoic acid consumption and the risk of depressive symptoms in US adults: Analyses from NHANES 2005–2018
    Chenxi Zhang, Bingnan Hou, Yan Xu, Shufei Zeng, Xue Luo, Bin Zhang · 2024 · Journal of Affective Disorders
  6. Exploration of the optimized portrait of omega-3 polyunsaturated fatty acids in treating depression: A meta-analysis of randomized-controlled trials
    Lingzhuo Kong, Qin Zhang, Huaizhi Wang, Yiran Xu, Chenyue Xu, Yiqing Chen, Jing Lu, Shaohua Hu · 2025 · Journal of Affective Disorders
  7. Differences between Japan and Taiwan in the treatment of pregnant women with depressive symptoms by omega-3 fatty acids: An open-label pilot study
    Daisuke Nishi, Kuan‐Pin Su, Kentaro Usuda, Jane Pei‐Chen Chang, Yi‐Ju Jill Chiang, Ta‐Wei Guu, Kei Hamazaki, Naoki Nakaya, Toshimasa Sone, Kenji Hashimoto et al. · 2017 · Nutritional Neuroscience
  8. Depression as an Inflammatory Disease
    Hoo Rim Song, Woo Young Sup, Won‐Myong Bahk · 2013 · 대한정신약물학회지
  9. The N-3 polyunsaturated fatty acids supplementation to prevent depression recurrence in patients with late-life depression: a 52-week double-blind, placebo-controlled trial
    Cheng, Ying-Chih, Chen, Wen-Yin, Lin, Chemin, Lee, Shwu-Hua, Chiu, Chih-Chiang, Kuo, Po-Hsiu · 2025 · Journal of Affective Disorders
  10. The Effectiveness of Transcranial Direct Current Stimulation (tDCS) and Omega-3 on Food Craving, Executive Functions, Weight, and Depressive Symptoms in Patients with Depression and Overweight: A Randomized Controlled Trial
    Mahla Tabasi, Seyed‐Ali Mostafavi, Hamidreza Oreyzi, Mohammad Reza Mohammadi, Ali Khaleghi · 2024 · Iranian Journal of Psychiatry
  11. Personalized Eicosapentaenoic Acid Therapy for Clinical Depression
    Halliru Zailani, David Mischoulon, Simon C. Dyall, Carmine Maria Pariante, Kuan‐Pin Su · 2025 · Psychiatric Annals
  12. Genetic polymorphisms of FADS1, FADS2, and FADS3 and fatty acid profiles in subjects received methadone maintenance therapy
    Hui-Ting Yang, Ruey-Yun Wang, Shih‐Yi Huang, Chieh‐Liang Huang, Kuan‐Pin Su · 2017 · Prostaglandins Leukotrienes and Essential Fatty Acids
  13. ω-3 Fatty Acids in Pediatric Major Depressive Disorder
    Gregor Emanuel Berger, Isabelle S. Häberling, Sophie Emery, Mona Albermann, Noemi Baumgartner, Kristin Nalani, Michael A. Strumberger, Lars Wöckel, Suzanne Erb, Silke Bachmann et al. · 2026 · JAMA Network Open
  14. Effect of Long-term Supplementation With Marine Omega-3 Fatty Acids vs Placebo on Risk of Depression
    Chih‐Sung Liang, Ping‐Tao Tseng, Kuan‐Pin Su · 2022 · JAMA
  15. Detecting the modest signals of omega-3 fatty acids' antidepressant effects by homogenizing depressed patient groups
    Senthil Kumaran Satyanarayanan, Yin‐Hua Shih, Kuan‐Pin Su · 2016 · Lipid Technology
  16. Omega-3 supplementation in migraine prophylaxis: An updated systematic review and meta-analysis
    Haneen Sabet, Abdallah Abbas, Ibraheem M. Alkhawaldeh, Shrouk Ramadan, Moaz Elsayed Abouelmagd, Ebrahem Salah Abdul-Hamid, Ahmed Elbataa, Mona Mahmoud Elsakka, Adel Mansour, Mostafa Hossam El Din Moawad et al. · 2025 · PharmaNutrition
  17. Treatments for depression: Side-effects, adverse events and health risks
    Irving Kirsch, Andy Ness, Katherine Marie Appleton · 2019 · Journal of Affective Disorders
  18. Examination of the nutritional value of four bivalves species from Bizerte lagoon
    Safa Bejaoui, Imen Rabeh, Imene Chetoui, TELAHIGUE, Khaled, Feriel Ghribi, Ch. Fouzai, EL CAFSI, Mohamed · 2022 · AquaDocs (United Nations Educational, Scientific and Cultural Organization)
  19. PTSD and the Attenuating Effects of Fish Oils: Results of Supplementation After the 2011 Great East Japan Earthquake
    Daisuke Nishi, Yuichi Koido, Naoki Nakaya, Toshimasa Sone, Hiroko Noguchi, Kei Hamazaki, Tomohito Hamazaki, Yutaka Matsuok · 2013 · InTech eBooks
  20. Acupuncture Treatment in Depression
    Kuan‐Pin Su, Li‐Wei Chou, Mao-Feng Sun, Jaung‐Geng Lin · 2018 · Springer eBooks
  21. Plasma Phospholipid Polyunsaturated Fatty Acid Associations with Neurocognition
    Jinjie Ling, John G. Keilp, Hanga Galfalvy, Vanessa N. Cardino, Alyina Ahmed, Ainsley K. Burke, Jenifer I. Fenton, J. John Mann, M. Elizabeth Sublette · 2023 · Nutrients
  22. Sex differences in nutritional psychiatry: Are omega-3 fatty acids more effective in women with MDD?
    Ilya V. Smolensky, Dragoš Inta, Kuan Pin Su, Wolfgang Marx · 2025 · Nutritional Psychiatry
  23. Role of Omega-3 Unsaturated Fatty Acids in the Postpartum Depression: Systematic Review and Narrative Synthesis
    Fatima Mougharbel, Raywat Deonandan · 2016 · Global Journal of Health Science
  24. The Psychology of Supplementation in Sport and Exercise: Motivational Antecedents and Biobehavioral Outcomes
    Shawn M. Arent, Rafer S. Lutz · 2015 · Springer eBooks
  25. Treatments for Comorbid Anxiety and Mood Disorders
    Jerome J. Sarris, David Mischoulon · 2016 · Springer eBooks
  26. Mental Illness in the Oldest-Old
    P. CULLEN · 2018 · Springer eBooks
  27. Reply to the Letter to the Editor: Response to “International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder” by Guu et al. (2019)
    Ta‐Wei Guu, Kuan‐Pin Su · 2019 · Psychotherapy and Psychosomatics
  28. Recognising Bipolar Disorders in Primary Care.
    Daniel Dietch · 2015 · PubMed
  29. Can Kampo and Dietary Supplement Address Unmet Need? – A Commentary on Tatsumi et al. and Hoffmann et al.
    Takashi Tsuboi · 2019 · Pharmacopsychiatry
  30. Supplementation with Omega-3 fatty acids in the supportive treatment of depression – systematic review
    Karolina Chmielarz, Magdalena Alicja Zapała, Adrian Krzysztof Hunek, Karolina Kaziród, Joanna Wiśniewska-Skomra, Kinga Tylutka, Anna Hapon · 2023 · Journal of Education Health and Sport
  31. Neuroprotection induced by omega-3 polyunsaturated fatty acids: focus on neuropsychiatric disorders
    Melissa Bujtor, Kuan‐Pin Su, Alessandra Borsini · 2024 · Elsevier eBooks
  32. Global and Epidemiological Perspectives on Diet and Mood
    Felice N. Jacka · 2016 · Elsevier eBooks
  33. Leveraging CAM to treat depression and anxiety
    Olagunju · 2020 · The Journal of Family Practice
  34. Omega-3 Fatty Acids for Depression, Revisited: The Jury Is Coming Back In
    Peter Roy‐Byrne · 2012 · Journal watch
  35. 25. Omega-3 polyunsaturated fatty acid potential for post-traumatic stress and depression
    Yutaka Matsuoka, Kei Hamazaki, Daisuke Nishi · 2015 · Wageningen Academic Publishers eBooks
  36. Ácidos grasos omega-3 y depresión: una revisión sistemática
    J. C. García, Esther Torío Ojea, L. J. Treviño, Secundino Fernández · 2017 · Psiquiatría Biológica
  37. Postpartum depression Part 2. Biological treatment: practical aspects & safety issues. Review of the literature
    Piotr A. Woźniak, Katarzyna Jankowska · 2020 · Wiedza Medyczna
  38. Diet, Immune System, and Psychiatric Disorders
    Jane Pei‐Chen Chang, Kuan‐Pin Su · 2021 · Springer eBooks
  39. Fish Oils
    Jae-Myung Kim, Man-Seok Park · 2021 · Stroke revisited
  40. Comprehensive Review of Ethnopharmacological and Phytochemical Aspects of Nutraceuticals in Psychiatric Disorders
    Samir Gunvantbhai Patel, Niraj Yashvantrai Vyas, Alkesh Patel, Umang Shah, Manan Raval, Mehul M. Patel, Archita J. Patel · 2022 · Current Psychopharmacologye
  41. Research Progress on the Transport Mechanism of Polyunsaturated Fatty Acids across the Blood-Brain Barrier and Their Potential Impact on Depression
    玲 张 · 2024 · Advances in Clinical Medicine
  42. Effect of vitamin D and omega-3 on the expression of endoplasmic reticulum-associated protein degradation and autophagic proteins in rat brain
    Ebru Alimoğulları, Bahar Kartal, Mehmet Fatih Bozkurt, Hazal Demir, Uygar Saçık, Muhammad Nasir Bhaya · 2024 · Turkish Journal of Biochemistry
  43. Additional file 1 of Association of serum fatty acid pattern with depression in U.S. adults: analysis of NHANES 2011–2012
    Hengying Chen, Wang, Jue, Baohua Zheng, Xia, Wenqi, Tan, Gongjun, Wu, Hongyuan, Wang, Yao, Deng, Zhen, Wang, Yiyuan, Jian Zhang et al. · 2024 · Figshare
  44. Diet, Food, Supplements, and Depression
    Franklin Sunzeri · 2026 · Springer eBooks
  45. The TSNPR vision: Implementation science as the missing link in nutritional psychiatry
    Jane Pei‐Chen Chang, Hui-Chih Chang, Li Jingling, Wolfgang Marx, Kuan‐Pin Su · 2026 · Nutritional Psychiatry