Image-guided, Lobe-specific Hydrodynamic Gene Delivery to Swine Liver

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

Liu, F., Song, Y. K., & Liu, D. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300947 · Cited by 1,728 · see citing works

High Levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA

Zhang, G., Budker, V. G., & Wolff, J. A. (1999) · Human Gene Therapy · doi:10.1089/10430349950017734 · Cited by 944 · see citing works

Hydrodynamic Gene Delivery: Its Principles and Applications

Suda, T., & Liu, D. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300314 · Cited by 349 · see citing works

Hydroporation as the mechanism of hydrodynamic delivery

Zhang, G., Gao, X., Song, Y. K., Vollmer, R. R., Stolz, D. B., Gasiorowski, J. Z., Dean, D. A., & Liu, D. (2004) · Gene Therapy · doi:10.1038/sj.gt.3302210 · Cited by 331 · see citing works

Gene therapy progress and prospects: Hydrodynamic gene delivery

Herweijer, H., & Wolff, J. A. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302891 · Cited by 189 · see citing works

Crossing the bridge: large animal models in translational transplantation research

Kirk, A. D. (2003) · Immunological Reviews · doi:10.1046/j.1600-065x.2003.00081.x · Cited by 146 · see citing works

Development of Catheter-Based Procedures for Transducing the Isolated Rabbit Liver with Plasmid DNA

Eastman, S. J., Baskin, K. M., Hodges, B. L., Chu, Q., Gates, A., Dreusicke, R., Anderson, S., & Scheule, R. K. (2002) · Human Gene Therapy · doi:10.1089/10430340260395910 · Cited by 135 · see citing works

Computer-assisted Hydrodynamic Gene Delivery

Suda, T., Suda, K., & Liu, D. (2008) · Molecular Therapy · doi:10.1038/mt.2008.66 · Cited by 107 · see citing works

Naked plasmid DNA transfer to the porcine liver using rapid injection with large volume

Yoshino, H. K. H., Hashizume, K., & Kobayashi, E. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302833 · Cited by 95 · see citing works

Uniform Scale-Independent Gene Transfer to Striated Muscle After Transvenular Extravasation of Vector

Su, L. T., Gopal, K., Wang, Z., Yin, X., Nelson, A., Kozyak, B. W., Burkman, J. M., Mitchell, M. A., Low, D. W., Bridges, C. R., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.534008 · Cited by 79 · see citing works

Pseudo-hydrodynamic Delivery of Helper-dependent Adenoviral Vectors into Non-human Primates for Liver-directed Gene Therapy

Brunetti‐Pierri, N., Stapleton, G. E., Palmer, D. J., Zuo, Y., Mane, V. P., Finegold, M. J., Beaudet, A. L., Leland, M. M., Mullins, C. E., & Ng, P. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300102 · Cited by 78 · see citing works

Hydrodynamic gene delivery to the pig liver via an isolated segment of the inferior vena cava

Fabre, J. W., Grehan, A., Whitehorne, M., Sawyer, G. J., Dong, X., Salehi, S., Eckley, L., Zhang, X., Seddon, M. D., Shah, A. M., et al. (2007) · Gene Therapy · doi:10.1038/sj.gt.3303079 · Cited by 76 · see citing works

Pig liver gene therapy by noninvasive interventionist catheterism

Aliño, S. F., Herrero, M. J., Noguera, I., Dası́, F., & Sánchez, M. (2006) · Gene Therapy · doi:10.1038/sj.gt.3302873 · Cited by 75 · see citing works

Increased Hepatic Transduction with Reduced Systemic Dissemination and Proinflammatory Cytokines Following Hydrodynamic Injection of Helper-Dependent Adenoviral Vectors

Brunetti‐Pierri, N., Palmer, D. J., Mane, V. P., Finegold, M. J., Beaudet, A. L., & Ng, P. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.03.001 · Cited by 67 · see citing works

Special stains in diagnostic liver pathology

Lefkowitch, J. H. (2006) · Seminars in Diagnostic Pathology · doi:10.1053/j.semdp.2006.11.006 · Cited by 61 · see citing works

Prolonged liver-specific transgene expression by a non-primate lentiviral vector

Condiotti, R., Curran, M. A., Nolan, G. P., Giladi, H., Ketzinel‐Gilad, M., Gross, E. Z., & Galun, E. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.06.044 · Cited by 34 · see citing works

Concepts of real-time photogrammetry

Maas, H. (1997) · Human Movement Science · doi:10.1016/s0167-9457(96)00049-8 · Cited by 20 · see citing works

Advances in Gene Delivery Systems

Kamimura, K., Suda, T., Zhang, G., & Liu, D. (2011) · Pharmaceutical Medicine · doi:10.1007/bf03256872 · Cited by 211 · see citing works

Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells

VandenDriessche, T., Ivics, Z., Izsvák, Z., & Chuah, M. (2009) · Blood · doi:10.1182/blood-2009-04-210427 · Cited by 150 · see citing works

The Sleeping Beauty transposon system: a non-viral vector for gene therapy

Aronovich, E. L., McIvor, R. S., & Hackett, P. B. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr140 · Cited by 143 · see citing works

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver

Hinrichs, A., Kessler, B., Kurome, M., Blutke, A., Kemter, E., Bernau, M., Scholz, A. M., Rathkolb, B., Renner, S., Bultmann, S., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.03.006 · Cited by 115 · see citing works

Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Izsvák, Z., Hackett, P. B., Cooper, L. J. N., & Ivics, Z. (2010) · BioEssays · doi:10.1002/bies.201000027 · Cited by 112 · see citing works

Minicircle DNA-based Gene Therapy Coupled With Immune Modulation Permits Long-term Expression of α-L-Iduronidase in Mice With Mucopolysaccharidosis Type I

Osborn, M. J., McElmurry, R. T., Lees, C. J., DeFeo, A. P., Chen, Z.-Y., Kay, M. A., Naldini, L., Freeman, G. J., Tolar, J., & Blazar, B. R. (2010) · Molecular Therapy · doi:10.1038/mt.2010.249 · Cited by 92 · see citing works

Mechanostructure and composition of highly reproducible decellularized liver matrices

Mattei, G., Di Patria, V., Tirella, A., Alaimo, A., Elia, G., Corti, A., Paolicchi, A., & Ahluwalia, A. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.10.023 · Cited by 78 · see citing works

Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver

Viecelli, H. M., Harbottle, R. P., Wong, S. P., Schlegel, A. A., Chuah, M., VandenDriessche, T., Harding, C. O., & Thöny, B. (2014) · Hepatology · doi:10.1002/hep.27104 · Cited by 74 · see citing works

Liver cell-targeted delivery of therapeutic molecules

Kang, J., Toita, R., & Murata, M. (2014) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2014.930017 · Cited by 60 · see citing works

Delivery Approaches for Therapeutic Genome Editing and Challenges

Ates, I., Rathbone, T., Stuart, C., Bridges, P. H., & Cottle, R. N. (2020) · Genes · doi:10.3390/genes11101113 · Cited by 60 · see citing works

Gene therapy for hemophilia

Herzog, R. W. (2015) · Frontiers in bioscience · doi:10.2741/4324 · Cited by 56 · see citing works

Efficacy and Safety of Sleeping Beauty Transposon-Mediated Gene Transfer in Preclinical Animal Studies

Hackett, P. B., Aronovich, E. L., Hunter, D. W., Urness, M., Bell, J. B., Kass, S. J., Cooper, L. J. N., & McIvor, S. R. (2011) · Current Gene Therapy · doi:10.2174/156652311797415827 · Cited by 53 · see citing works

Delivery of Full-Length Factor VIII Using a piggyBac Transposon Vector to Correct a Mouse Model of Hemophilia A

Matsui, H., Fujimoto, N., Sasakawa, N., Ohinata, Y., Shima, M., Yamanaka, S., Sugimoto, M., & Hotta, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104957 · Cited by 51 · see citing works

Gene therapy for hemophilia

Chuah, M., Evens, H., & VandenDriessche, T. (2013) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12215 · Cited by 48 · see citing works

Image-guided, Intravascular Hydrodynamic Gene Delivery to Skeletal Muscle in Pigs

Kamimura, K., Zhang, G., & Liu, D. (2009) · Molecular Therapy · doi:10.1038/mt.2009.206 · Cited by 48 · see citing works

Validation of Mitochondrial Gene Delivery in Liver and Skeletal Muscle via Hydrodynamic Injection Using an Artificial Mitochondrial Reporter DNA Vector

Yasuzaki, Y., Yamada, Y., Ishikawa, T., & Harashima, H. (2015) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5b00511 · Cited by 48 · see citing works

Physical Methods for Gene Transfer

Alsaggar, M., & Liu, D. (2014) · Advances in genetics · doi:10.1016/bs.adgen.2014.10.001 · Cited by 48 · see citing works

Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs

Kamimura, K., Kanefuji, T., Yokoo, T., Abé, H., Suda, T., Kobayashi, Y., Zhang, G., Aoyagi, Y., & Liu, D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107203 · Cited by 46 · see citing works

Gene Therapy for Liver Cancers: Current Status from Basic to Clinics

Kamimura, K., Yokoo, T., Abé, H., & Terai, S. (2019) · Cancers · doi:10.3390/cancers11121865 · Cited by 45 · see citing works

Gene therapy strategies for hemophilia: benefits versus risks

Petrus, I., Chuah, M., & VandenDriessche, T. (2010) · Journal of Gene Medicine · doi:10.1002/jgm.1500 · Cited by 44 · see citing works

Liver-targeted hydrodynamic gene therapy: Recent advances in the technique

Yokoo, T., Kamimura, K., Abé, H., Kobayashi, Y., Kanefuji, T., Ogawa, K., Goto, R., Oda, M., Suda, T., & Terai, S. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i40.8862 · Cited by 43 · see citing works

Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein

Dalsgaard, T. K., Cecchi, C. R., Askou, A. L., Bak, R. O., Andersen, P. O., HOUGAARD, D. M., Jensen, T. G., Dagnæs‐Hansen, F., Mikkelsen, J. G., Corydon, T. J., et al. (2018) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2018.07.005 · Cited by 41 · see citing works

Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver

Kamimura, K., Suda, T., Zhang, G., Aoyagi, Y., & Liu, D. (2013) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2013.52 · Cited by 39 · see citing works

Effective Prevention of Liver Fibrosis by Liver-targeted Hydrodynamic Gene Delivery of Matrix Metalloproteinase-13 in a Rat Liver Fibrosis Model

Abé, H., Kamimura, K., Kobayashi, Y., Ohtsuka, M., Miura, H., Ohashi, R., Yokoo, T., Kanefuji, T., Suda, T., Tsuchida, M., et al. (2016) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2015.49 · Cited by 39 · see citing works

Hydrodynamic delivery of adiponectin and adiponectin receptor 2 gene blocks high-fat diet-induced obesity and insulin resistance

Ma, Y., & Liu, D. (2013) · Gene Therapy · doi:10.1038/gt.2013.8 · Cited by 37 · see citing works

Long-term phenotypic correction in factor IX knockout mice by using phiC31 integrase-mediated gene therapy

Keravala, A., Chavez, C. L., Hu, G., Woodard, L. E., Monahan, P. E., & Calos, M. P. (2011) · Gene Therapy · doi:10.1038/gt.2011.31 · Cited by 36 · see citing works

In vivo Site-Specific Transfection of Naked Plasmid DNA and siRNAs in Mice by Using a Tissue Suction Device

Shimizu, K., Kawakami, S., Hayashi, K., Kinoshita, H., Kuwahara, K., Nakao, K., Hashida, M., & Konishi, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041319 · Cited by 34 · see citing works

DNA delivery to ‘ex vivo’ human liver segments

Herrero, M. J., Sabater, L., Güenechea, G., Sendra, L., Montilla, A. I., Abargues, R., Navarro, V., & Aliño, S. F. (2011) · Gene Therapy · doi:10.1038/gt.2011.144 · Cited by 32 · see citing works

Hydrodynamic Delivery: Characteristics, Applications, and Technological Advances

Suda, T., Yokoo, T., Kanefuji, T., Kamimura, K., Zhang, G., & Liu, D. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041111 · Cited by 31 · see citing works

Zinc finger nucleases: Tailor-made for gene therapy

Chou, S.-T., Leng, Q., & Mixson, A. J. (2012) · Drugs of the Future · doi:10.1358/dof.2012.37.3.1779022 · Cited by 29 · see citing works

Technical Improvement and Application of Hydrodynamic Gene Delivery in Study of Liver Diseases

Huang, M.-J., Sun, R., Huang, Q., & Tian, Z. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00591 · Cited by 26 · see citing works

Liver tissue engineering using decellularized scaffolds: Current progress, challenges, and opportunities

Hussein, K. H., Ahmadzada, B., Correa, J. C., Sultan, A., Wilken, S., Amiot, B., & Nyberg, S. L. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.06.001 · Cited by 28 · see citing works

Comparison of Thiel preserved, fresh human, and animal liver tissue in terms of mechanical properties

Estermann, S.-J., Förster-Streffleur, S., Hirtler, L., Streicher, J., Pahr, D. H., & Reisinger, A. (2021) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2021.151717 · Cited by 27 · see citing works

Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions

Kamimura, K., Yokoo, T., Abé, H., Kobayashi, Y., Ogawa, K., Shinagawa, Y., Inoue, R., & Terai, S. (2015) · Pharmaceutics · doi:10.3390/pharmaceutics7030213 · Cited by 26 · see citing works

Novel electric power-driven hydrodynamic injection system for gene delivery: safety and efficacy of human factor IX delivery in rats

Yokoo, T., Kamimura, K., Suda, T., Kanefuji, T., Oda, M., Zhang, G., Liu, D., & Aoyagi, Y. (2013) · Gene Therapy · doi:10.1038/gt.2013.2 · Cited by 26 · see citing works

The therapeutic potential of phiC31 integrase as a gene therapy system

Karow, M., & Calos, M. P. (2011) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2011.601293 · Cited by 26 · see citing works

Intracellular Gene Transfer in Rats by Tail Vein Injection of Plasmid DNA

Zhou, T., Kamimura, K., Zhang, G., & Liu, D. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9231-z · Cited by 23 · see citing works

Hydrodynamic Delivery

Suda, T., & Liu, D. (2014) · Advances in genetics · doi:10.1016/bs.adgen.2014.10.002 · Cited by 22 · see citing works

Successful liver-directed gene delivery by ERCP-guided hydrodynamic injection (with videos)

Kumbhari, V., Li, L., Piontek, K., Ishida, M., Fu, R., Khalil, B., Garrett, C. M., Liapi, E. A., Kalloo, A. N., & Selaru, F. M. (2018) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2018.06.022 · Cited by 22 · see citing works

Hemodynamics of a hydrodynamic injection

Kanefuji, T., Yokoo, T., Suda, T., Abé, H., Kamimura, K., & Liu, D. (2014) · Molecular Therapy — Methods & Clinical Development · doi:10.1038/mtm.2014.29 · Cited by 21 · see citing works

Critical Physiological and Surgical Considerations for Hydrodynamic Pressurization of Individual Segments of the Pig Liver

Fabre, J. W., Whitehorne, M., Grehan, A., Sawyer, G. J., Zhang, X., Davenport, M., & Rela, M. (2010) · Human Gene Therapy · doi:10.1089/hum.2010.144 · Cited by 20 · see citing works

Zinc finger nucleases: Tailor-made for gene therapy

Chou, S., Leng, Q., & Mixson, A. J. (2012) · Drugs of the Future · doi:10.1358/dof.2012.037.03.1779022 · Cited by 39 · see citing works

Impact of Hydrodynamic Injection and phiC31 Integrase on Tumor Latency in a Mouse Model of MYC-Induced Hepatocellular Carcinoma

Woodard, L. E., Keravala, A., Jung, W. E., Wapinski, O. L., Yang, Q., Felsher, D. W., & Calos, M. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011367 · Cited by 18 · see citing works

Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma

Kamimura, K., Yokoo, T., Abé, H., Sakai, N., Nagoya, T., Kobayashi, Y., Ohtsuka, M., Miura, H., Sakamaki, A., Kamimura, H., et al. (2020) · Cancers · doi:10.3390/cancers12020472 · Cited by 18 · see citing works

Hepatocyte Transfection in Small Pigs After Weaning by Hydrodynamic Intraportal Injection of Naked DNA/Minicircle Vectors

Stoller, F., Schlegel, A. A., Viecelli, H. M., Rüfenacht, V., Cesarovic, N., Viecelli, C., Deplazes, S., Bettschart‐Wolfensberger, R., Hurter, K., Schmierer, P. A., et al. (2015) · Human Gene Therapy Methods · doi:10.1089/hgtb.2014.140 · Cited by 17 · see citing works

Physical Methods of Gene Delivery

Herrero, M. J., Sendra, L., Miguel, A., & Aliño, S. F. (2017) · Springer eBooks · doi:10.1007/978-3-319-53457-2_6 · Cited by 16 · see citing works

Advances in Overcoming Immune Responses following Hemophilia Gene Therapy

H. Miao, C. (2012) · Journal of Genetic Syndromes & Gene Therapy · doi:10.4172/2157-7412.s1-007 · Cited by 15 · see citing works

A Surgical Model for Isolating the Pig Liver in vivo for Gene Therapy

Carreño, O., Sendra, L., Montalvá, E. M., Miguel, A. P. R., Orbís, F., Herrero, M. J., Noguera, I., Aliño, S. F., & López‐Andújar, R. (2013) · European Surgical Research · doi:10.1159/000351339 · Cited by 15 · see citing works

Studying Closed Hydrodynamic Models of “In Vivo” DNA Perfusion in Pig Liver for Gene Therapy Translation to Humans

Sendra, L., Miguel, A., Pérez-Enguix, D., Herrero, M. J., Montalvá, E. M., García-Gimeno, M. A., Noguera, I., Díaz, A., Pérez, J., Sanz, P., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163898 · Cited by 15 · see citing works

Technical requirements for effective regional hydrodynamic gene delivery to the left lateral lobe of the rat liver

Sawyer, G. J., Zhang, X., & Fabre, J. W. (2010) · Gene Therapy · doi:10.1038/gt.2009.167 · Cited by 14 · see citing works

Improved molecular platform for the gene therapy of rare diseases by liver protein secretion

Quiviger, M., Giannakopoulos, A., Verhenne, S., Marie, C., Stavrou, E. F., Vanhoorelbeke, K., Izsvák, Z., Meyer, S. F. D., Athanassiadou, A., & Scherman, D. (2018) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2018.04.010 · Cited by 13 · see citing works

Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery

Kobayashi, Y., Kamimura, K., Abé, H., Yokoo, T., Ogawa, K., Shinagawa‐Kobayashi, Y., Goto, R., Inoue, R., Ohtsuka, M., Miura, H., et al. (2016) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2016.63 · Cited by 13 · see citing works

Transgene Expression in Dogs After Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons Using Balloon Catheters

Hyland, K. A., Aronovich, E. L., Olson, E. R., Bell, J. B., Urness, M., Günther, R., Hunter, D. W., Hackett, P. B., & McIvor, R. S. (2017) · Human Gene Therapy · doi:10.1089/hum.2017.003 · Cited by 12 · see citing works

Low RNA translation activit limits the efficacy of hydrodynamic gene transfer to pig liver in vivo

Sendra, L., Carreño, O., Miguel, A., Montalvá, E. M., Herrero, M. J., Orbís, F., Noguera, I., Barettino, D., López‐Andújar, R., & Aliño, S. F. (2014) · The Journal of Gene Medicine · doi:10.1002/jgm.2777 · Cited by 12 · see citing works

Transcutaneous Ultrasound-Mediated Nonviral Gene Delivery to the Liver in a Porcine Model

Tran, D. M., Zhang, F., Morrison, K. P., Loeb, K. R., Harrang, J., Kajimoto, M., Chavez, F., Wu, L. G., & Miao, C. H. (2019) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2019.07.005 · Cited by 12 · see citing works

Delivery of Nucleic Acids and Gene Delivery

Akita, H., Hatakeyama, H., Khalil, I. A., Yamada, Y., & Harashima, H. (2011) · Comprehensive Biomaterials · doi:10.1016/b978-0-08-055294-1.00150-1 · Cited by 12 · see citing works

Efficacy and Safety of Pancreas-Targeted Hydrodynamic Gene Delivery in Rats

Ogawa, K., Kamimura, K., Kobayashi, Y., Abé, H., Yokoo, T., Sakai, N., Nagoya, T., Sakamaki, A., Abe, S., Hayashi, K., et al. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2017.08.009 · Cited by 12 · see citing works

Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection

Chan, T., Grisch‐Chan, H. M., Schmierer, P. A., Subotic, U., Rimann, N., Scherer, T., Hetzel, U., Bozza, M., Harbottle, R. P., Williams, J. A., et al. (2022) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2022.01.006 · Cited by 13 · see citing works

Efficacy of hydrodynamic interleukin 10 gene transfer in human liver segments with interest in transplantation

Sendra, L., Matas, A. M., Ortí, L. S., Herrero, M. J., Olivas, L. S., Montalvá, E. M., Frasson, M., Abargues, R., López‐Andújar, R., Ximénez, E. G., et al. (2016) · Liver Transplantation · doi:10.1002/lt.24667 · Cited by 11 · see citing works

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney

Woodard, L. E., Welch, R. C., Williams, F. M., Luo, W., Cheng, J., & Wilson, M. H. (2018) · Journal of Visualized Experiments · doi:10.3791/56324 · Cited by 10 · see citing works

Human AAT gene transfer to pig liver improved by using a perfusion isolated organ endovascular procedure

Sendra, L., Pérez, D., Miguel, A., Herrero, M. J., Noguera, I., Díaz, A., Barettino, D., Martí‐Bonmatí, L., & Aliño, S. F. (2015) · European Radiology · doi:10.1007/s00330-015-3792-2 · Cited by 10 · see citing works

Parameters of biliary hydrodynamic injection during endoscopic retrograde cholangio-pancreatography in pigs for applications in gene delivery

Huang, Y., Kruse, R. L., Ding, H., Itani, M. I., Morrison, J. J., Wang, Z. Z., Selaru, F. M., & Kumbhari, V. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249931 · Cited by 9 · see citing works

Challenges of experimental gene therapy for urea cycle disorders

Viecelli, H. M., & Thöny, B. (2014) · Zurich Open Repository and Archive (University of Zurich) · doi:10.3233/jpb-140107 · Cited by 8 · see citing works

Hepatic control elements promote long‐term expression of human coagulation factor IX gene in hydrodynamically transfected mice

Kim, H. S., Kim, J. C., Lee, Y. K., Kim, J. S., & Park, Y. S. (2011) · The Journal of Gene Medicine · doi:10.1002/jgm.1583 · Cited by 8 · see citing works

Ultrasound-Mediated Gene Delivery

Carol, H., & Andrew, A. (2011) · InTech eBooks · doi:10.5772/21196 · Cited by 7 · see citing works

Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver

Kruse, R. L., Huang, Y., Shum, T., Bai, L., Ding, H., Wang, Z., Selaru, F. M., & Kumbhari, V. (2021) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2021.06.016 · Cited by 7 · see citing works

Gene Therapy with Plasmid DNA

Bathula, S. R., & Huang, L. (2010) · Burger's Medicinal Chemistry and Drug Discovery · doi:10.1002/0471266949.bmc073.pub2 · Cited by 7 · see citing works

Determining Transgene Expression Characteristics Using a Suction Device with Multiple Hole Adjusting a Left Lateral Lobe of the Mouse Liver

Haraguchi, A., Fuchigami, Y., Kawaguchi, M., Fumoto, S., Ohyama, K., Shimizu, K., Hagimori, M., & Kawakami, S. (2018) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b18-00094 · Cited by 6 · see citing works

Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice

Liu, J., Li, W., Limbu, M. H., Li, Y., Wang, Z., Cheng, Z., Zhang, X., & Chen, P. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00555 · Cited by 6 · see citing works

Efficient liver gene transfer with foamy virus vectors

Zacharoulis, D., Rountas, C., Katsimpoulas, M., Morianos, J., Chatziandreou, I., & Vassilopoulos, G. (2013) · Medical science monitor basic research/Medical science monitor. Basic research · doi:10.12659/msmbr.883996 · Cited by 5 · see citing works

Liver-directed Gene Therapy

Kamimura, K., Abé, H., Suda, T., & Liu, D. (2013) · Cited by 5 · see citing works

Advances in tissue optical clearing for 3D imaging in large animal

Deng, Y., Xu, J., Yu, T., & Zhu, D. Y. (2025) · Frontiers of Optoelectronics · doi:10.1007/s12200-025-00162-6 · Cited by 4 · see citing works

Antisense Technology: From Unique Laboratory Tool to Novel Anticancer Treatments

Cresce, C. D., Way, C., Rytelewski, M., Vareki, S. M., Nilam, S., Vincent, M. D., Koropatnick, J. D., & Ferguson, P. J. (2012) · RNA technologies · doi:10.1007/978-3-642-27426-8_7 · Cited by 4 · see citing works

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model

Noda, M., Tatsumi, K., Matsui, H., Matsunari, Y., SATO, T. A., Fukuoka, Y., Hotta, A., Okano, T., Kichikawa, K., Sugimoto, M., et al. (2021) · Regenerative Therapy · doi:10.1016/j.reth.2021.08.009 · Cited by 4 · see citing works

Minimal Invasive Technique for Gene Delivery in Porcine Liver Lobe Segment

Katsimpoulas, M., Zacharoulis, D., Rountas, C., Dimitriou, C. A., Mantziaras, G., Kostomitsopoulos, N. G., Habib, N. A., & Kostakis, A. I. (2011) · Journal of Investigative Surgery · doi:10.3109/08941939.2010.519815 · Cited by 4 · see citing works

Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene delivery method

Shibata, O., Kamimura, K., Tanaka, Y., Ogawa, K., Owaki, T., Oda, C., Morita, S., Kimura, A., Abé, H., Ikarashi, S., et al. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.03.019 · Cited by 3 · see citing works

Nucleic Acid-Based Therapy: Development of a Nonviral-Based Delivery Approach

Yokoo, T., Kamimura, K., Kanefuji, T., Suda, T., & Terai, S. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.80741 · Cited by 3 · see citing works

Liver lobe-specific hydrodynamic gene delivery to baboons: A preclinical trial for hemophilia gene therapy

Kamimura, K., Kanefuji, T., Suda, T., Yokoo, T., Zhang, G., Aoyagi, Y., & Liu, D. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.05.018 · Cited by 3 · see citing works

Hydrodynamic gene delivery

Kamimura, K., Suda, T., & Liu, D. (2015) · doi:10.4155/fseb2013.13.103 · Cited by 3 · see citing works

Gene Therapy with Plasmid DNA

Liu, Y., Musetti, S., & Huang, L. (2021) · Burger's Medicinal Chemistry and Drug Discovery · doi:10.1002/0471266949.bmc073.pub3 · Cited by 3 · see citing works

siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles

Cau, M. F., Ferraresso, F., Seadler, M. S., Badior, K. E., Zhang, Y., Ketelboeter, L. M., Rodriguez, G. G., Chen, T. J., Ferraresso, M., Wietrzny, A., et al. (2024) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2024.101258 · Cited by 2 · see citing works

Hepatic Gene Therapy

Nakai, H. (2010) · Molecular pathology library · doi:10.1007/978-1-4419-7107-4_23 · Cited by 2 · see citing works

Animal Models for Hydrodynamic Gene Delivery

Katsimpoulas, M., Zacharoulis, D., Habib, N. A., & Kostakis, A. I. (2012) · InTech eBooks · doi:10.5772/35118 · Cited by 2 · see citing works

Advancements in Non Viral Gene Therapy for Hemophilia

Fletcher, B. S. (2012) · Journal of Genetic Syndromes & Gene Therapy · doi:10.4172/2157-7412.s1-002 · Cited by 2 · see citing works

Image-Guided Hydrodynamic Gene Delivery to the Liver: Toward Clinical Applications

Kamimura, K., Suda, T., Kanefuji, T., Yokoo, T., Abé, H., Kobayashi, Y., Aoyagi, Y., & Liu, D. (2015) · Springer eBooks · doi:10.1007/978-4-431-55666-4_8 · Cited by 2 · see citing works

Liver-Targeted Gene and Cell Therapies: An Overview

Alsaggar, M., & Liu, D. (2015) · Springer eBooks · doi:10.1007/978-4-431-55666-4_1 · Cited by 2 · see citing works

Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated ‘in vivo’ by surgical procedure with interest in liver transplantation

Sendra, L., Herrero, M. J., Montalvá, E. M., Noguera, I., Orbís, F., Díaz, A., Fernández‐Delgado, R., López‐Andújar, R., & Aliño, S. F. (2019) · PLoS ONE · doi:10.1371/journal.pone.0224568 · Cited by 2 · see citing works

Gene Therapy for Von Willebrand Disease

Chuah, M., Petrus, I., & VandenDriessche, T. (2011) · doi:10.1002/9781444329926.ch20 · Cited by 2 · see citing works

Recent advances in gene therapy for neurological disorders: A comprehensive overview

Jindal, D. (2025) · Adesh University Journal of Medical Sciences & Research · doi:10.25259/aujmsr_20_2025 · Cited by 1 · see citing works

Hydrodynamic Delivery of IL-10 Gene for Local Immunomodulation in Human Crohn’s Disease Tissue: A Proof-of-Concept Study

Sendra, L., Giner, F., Olivera, G. G., Herrero, M. J., Zucchet, E. G., Aliño, S. F., & Frasson, M. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18040442 · Cited by 1 · see citing works

Comparison of CT Dose Reduction Algorithms in a Porcine Model

Khan, M. N., Elbakri, I. A., Henderson, B. T., Mottola, J. C., & Omotayo, A. A. (2015) · Advances in Computed Tomography · doi:10.4236/act.2015.44008 · Cited by 1 · see citing works

Hypothesis, Inserting Bacterial Natural Transformation Protein Complexes Into Human Cells For Efficient Gene Therapy Using Naked Dna

Tolmachov, O. E. (2010) · Spiral (Imperial College London) · Cited by 1 · see citing works

Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Izsvák, Z., Hackett, P. B., Cooper, L. J. N., & Ivics, Z. (2011) · BioEssays · doi:10.1002/bies.201190025 · Cited by 1 · see citing works

Nonviral Gene Therapy—The Challenge of Mobilizing DNA

Mikkelsen, J. G. (2015) · Springer eBooks · doi:10.1007/978-1-4939-2389-2_4

Effectiveness and safety of hydrodynamic gene delivery in animals with fibrotic liver

Zhou, T. (2011) · D-Scholarship@Pitt (University of Pittsburgh)

HYDRODYNAMIC-PRESSURE-BASED NON-VIRAL NUCLEIC ACID DELIVERY

Suda, T., Kamimura, K., Zhang, G., & Liu, D. (2019) · WORLD SCIENTIFIC (EUROPE) eBooks · doi:10.1142/9781786346889_0016

Hydrodynamic delivery for cancer and obesity research

Alsaggar, M. H. (2016)

Liver Gene Therapy: Employing Surgery and Radiology for Translational Research

Sendra, L., Herrero, M. J., Martí‐Bonmatí, L., Montalvá, E. M., López‐Andújar, R., Frasson, M., García‐Granero, E., & Pellicer, S. F. A. (2018) · InTech eBooks · doi:10.5772/intechopen.72665

Advances in Overcoming Immune Responses following Hemophilia Gene

Miao, T. (2011)

Hydrodynamic gene delivery to the pig liver via an isolated segment of the inferior vena cava

Fabre, J. W., Grehan, A., Whitehorne, M., Sawyer, G. J., Dong, X., Salehi, S., Eckley, L., Zhang, X., Seddon, M. D., Shah, A. M., et al. (2007) · Gene Therapy · doi:10.1038/sj.gt.3303079 · Cited by 76 · see citing works

Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver

Kamimura, K., Suda, T., Zhang, G., Aoyagi, Y., & Liu, D. (2013) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2013.52 · Cited by 39 · see citing works

267. Image-Guided, Liver-Targeted Hydrodynamic Gene Delivery in Dogs – Preclinical Assessment of Effectiveness and Safety of the Procedure

Kamimura, K., Abé, H., Yokoo, T., Kanefuji, T., Suda, T., Kobayashi, Y., Zhang, G., Oda, M., Aoyagi, Y., Terai, S., et al. (2015) · Molecular Therapy · doi:10.1016/s1525-0016(16)33876-x

Site-Specific Impact of a Regional Hydrodynamic Injection: Computed Tomography Study during Hydrodynamic Injection Targeting the Swine Liver

Yokoo, T., Kanefuji, T., Suda, T., Kamimura, K., Liu, D., & Terai, S. (2015) · Pharmaceutics · doi:10.3390/pharmaceutics7030334 · Cited by 9 · see citing works

17. Image-Guided Hydrodynamic Gene Delivery to Pig Liver

(2008) · Molecular Therapy · doi:10.1016/s1525-0016(16)39420-5