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Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models

Kazuki, Yasuhiro, Oshimura, Mitsuo·2011·Molecular Therapy
DOI 10.1038/mt.2011.136
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  • Human artificial chromosomes (HACs) are capable of large insertions that can be maintained episomally under physiological conditions.

    “Another alternative is to place such transgenes in human artificial chromosomes (HACs) capable of large insertions that can be maintained episomally under physiological conditions [172].”

    From The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics (2022) · cites this paper as [172]

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Metadata

Authors
Kazuki, Y., & Oshimura, M.
Venue
Molecular Therapy
Publisher
Elsevier BV
Published
2011-09
Volume
19
Issue
9
Pages
1591-1601
ISSN
1525-0016
DOI
10.1038/mt.2011.136
Cited by
108
References
5
Language
en
Licence

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