Production of lentiviral vectors

Merten, Otto-Wilhelm, Hebben, Matthias, Bovolenta, Chiara·2016·Molecular Therapy - Methods & Clinical Development

DOI 10.1038/mtm.2016.17

Cited by (294)

Items 101–200 of 294

Continuous manufacturing of lentiviral vectors using a stable producer cell line in a fixed-bed bioreactor
Dale J. Stibbs, Pedro Silva Couto, Yasuhiro Takeuchi, Qasim A. Rafiq, Nigel B. Jackson, Andrea C. M. E. Rayat · 2024 · Molecular Therapy — Methods & Clinical Development
Progressing from transient to stable packaging cell lines for continuous production of lentiviral and gammaretroviral vectors
Jaeyoung Park, Sarah Inwood, Srivalli Kruthiventi, Jackson P. Jenkins, Joseph Shiloach, Michael J. Betenbaugh · 2018 · Current Opinion in Chemical Engineering
Enzymatically amplified linear dbDNATM as a rapid and scalable solution to industrial lentiviral vector manufacturing
Maria Barreira, Claire Kerridge, Sara Jorda, Didrik Olofsson, Alexander Neumann, Helen Horton, Sarah Smith‐Moore · 2022 · Gene Therapy
Packaging cells for lentiviral vectors generated using the cumate and coumermycin gene induction systems and nanowell single-cell cloning
Sophie Broussau, Viktoria Lytvyn, Mélanie Simoneau, Claire Guilbault, Mélanie Leclerc, Nazila Nazemi-Moghaddam, Nathalie Coulombe, Seyyed Mehdy Elahi, Scott McComb, Rénald Gilbert · 2023 · Molecular Therapy — Methods & Clinical Development
Digital Twin for Continuous Production of Virus-like Particles toward Autonomous Operation
Alina Hengelbrock, Finja Probst, Simon Baukmann, Alexander Uhl, Natalie Tschorn, Jörn Stitz, A. Schmidt, Jochen Strube · 2024 · ACS Omega
The Superiority of Sucrose Cushion Centrifugation to Ultrafiltration and PEGylation in Generating High-Titer Lentivirus Particles and Transducing Stem Cells with Enhanced Efficiency
Mahdi Eskandarian Boroujeni, Mossa Gardaneh · 2018 · Molecular Biotechnology
Cocaine‐ and amphetamine‐regulated transcript peptide in the nucleus accumbens shell inhibits cocaine‐induced locomotor sensitization to transient over‐expression of α‐Ca2+/calmodulin‐dependent protein kinase II
Lixia Xiong, Meng Qing, Xi Sun, Xiangtong Lu, Qiang Fu, Qinghua Peng, Jianhua Yang, Ki‐Wan Oh, Zhenzhen Hu · 2018 · Journal of Neurochemistry
Bioprocess monitoring and control: challenges in cell and gene therapy
Joe Emerson, Jarka Glassey · 2021 · Current Opinion in Chemical Engineering
End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics
Annette M. Medina, Alavattam Sreedhara, Jakob W. Buecheler, Sebastian Brosig, Danny K. Chou, Twinkle R. Christian, Tapan Kanti Das, Isabella de Jong, Jonas L. Fast, Bharat Jagannathan et al. · 2022 · The AAPS Journal
Scalable manufacturing of gene-modified human mesenchymal stromal cells with microcarriers in spinner flasks
Pedro Silva Couto, Dale J. Stibbs, Marco C. Rotondi, Yasuhiro Takeuchi, Qasim A. Rafiq · 2023 · Applied Microbiology and Biotechnology
Development of KoRV-pseudotyped lentiviral vectors for efficient gene transfer into freshly isolated immune cells
Alexander Renner, Anika Stahringer, Katharina Eva Ruppel, Stephan Fricke, Ulrike Koehl, Dominik Schmiedel · 2024 · Gene Therapy
A novel scalable, robust downstream process for oncolytic rat parvovirus: isoelectric point-based elimination of empty particles
Barbara Leuchs, Veronika Frehtman, Markus Riese, Marcus Christian Müller, Jean Rommelaere · 2017 · Applied Microbiology and Biotechnology
Generation of Knockout Human Primary Keratinocytes by CRISPR/Cas9
Serena Grossi, Gabriele Fenini, Paulina Hennig, Michela Di Filippo, Hans‐Dietmar Beer · 2019 · Methods in molecular biology
Interference chromatography: a novel approach to optimizing chromatographic selectivity and separation performance for virus purification
Lisa A. Santry, Renaud Jacquemart, Melissa Vandersluis, Mochao Zhao, Jake M. Domm, Thomas M. McAusland, Xiaojiao Shang, Pierre M. Major, James G. Stout, Sarah K. Wootton · 2020 · BMC Biotechnology
Viral and non-viral vectors for gene therapy in the treatment of bone-related disorders: molecular insights and clinical perspectives
Heng’an Ge, Zhenting Shi, Centao Liu, Jingwei Lu, Ying Yao, Biao Cheng · 2025 · Molecular Aspects of Medicine
Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture
Saqlain Suleman, Serena Fawaz, Terry Roberts, Stuart M. Ellison, Brian Bigger, Michael Themis · 2024 · Journal of Virological Methods
Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral Vectors
Ane Arrasate, Igone Bravo, Carlos Lopez-Robles, Ane Arbelaiz-Sarasola, Maddi Ugalde, Martha Lucia Meijueiro, Miren Zuazo, Ana Valero, Soledad Baños-Mateos, Juan Carlos Ramı́rez et al. · 2024 · Biomedicines
Clinical grade lentiviral vector purification and quality control requirements
Ruina Shi, Shenghua Jia, Huwei Liu, Honggang Nie · 2022 · Journal of Separation Science
High-Titer Production of HIV-Based Lentiviral Vectors in Roller Bottles for Gene and Cell Therapy
Hazal Banu Olgun Celebioglu, Hale M. Tasyurek, Ahter Dilşad Şanlioğlu, Salih Şanlıoğlu · 2018 · Methods in molecular biology
Lentivirus Manufacturing Process for Primary T‐Cell Biofactory Production
Harikrishnan Radhakrishnan, Harold S. Javitz, Parijat Bhatnagar · 2020 · Advanced Biosystems
Trojan Horse-Like Vehicles for CRISPR-Cas Delivery: Engineering Extracellular Vesicles and Virus-Like Particles for Precision Gene Editing in Cystic Fibrosis
Laudonia Lidia Dipalo, Jacob Giehm Mikkelsen, Rik Gijsbers, Marianne Sylvia Carlon · 2025 · Human Gene Therapy
Generation of stable suspension producer cell lines for serum‐free lentivirus production
Maximilian Klimpel, Monica Cristina Terrão, Melina Bräuer, Herbert Dersch, Martina Biserni, Larissa Mélo do Nascimento, Sarah Schwingal, Jessica E. Vogel, Cathrin Ferlemann, Tobias Brandt et al. · 2024 · Biotechnology Journal
Integrasone Derivatives Isolated from Lepteutypa sp. KT4162 and Their Anti-HIV-1 Integrase Activity
Satomi Miura, Kotaro Ishida, Kazuaki Tanaka, Eiji Morita, Masaru Hashimoto · 2023 · Journal of Natural Products
Forced expression of HOXA13 confers oncogenic hallmarks to esophageal keratinocytes
Kateryna Nesteruk, Vincent T. Janmaat, Hui Liu, Timo L.M. ten Hagen, Maikel Petrus Peppelenbosch, Gwenny Manel Fuhler · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Lentiviral mediated gene delivery as an effective therapeutic approach for Parkinson disease
Violina Kakoty, K C Sarathlal, Sunil Kumar Dubey, Chih Hao Yang, Prashant Kesharwani, Rajeev Taliyan · 2021 · Neuroscience Letters
A platform method for plasmid isoforms analysis by capillary gel electrophoresis
Meng Wang, Jun‐Kai Liu, Tie Gao, Ling‐Li Xu, Xiaoxia Zhang, Jianhui Nie, Yan Li, Hong‐Xu Chen · 2022 · Electrophoresis
Mitofusin2 regulates the proliferation and function of fibroblasts: The possible mechanisms underlying pelvic organ prolapse development
Xiaoqing Wang, Xiaoxiao Wang, Yingfang Zhou, Chao Peng, Huayun Chen, Ye Feng Lu · 2019 · Molecular Medicine Reports
Lentiviral vector packaging and producer cell lines yield titers equivalent to the industry-standard four-plasmid process
Matthew Tridgett, Marie Mulet, S. Parokkaran Johny, Maria Ababi, M. Raghunath, Chloé Fustinoni, Boryana Galabova, Cristina Fernández-Díaz, Iveta Mikalajūnaitė, Hélio A. Tomás et al. · 2024 · Molecular Therapy — Methods & Clinical Development
Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones cultivated at high cell density
Chun Fang Shen, Sonia Tremblay, Catherine Sabourin-Poirier, Elodie Burney, Sophie Broussau, Aziza P. Manceur, Anja Rodenbrock, Robert Voyer, Martin Loignon, Sven Ansorge et al. · 2022 · Bioprocess and Biosystems Engineering
Exploring nutrient supplementation and bioprocess optimization to improve the production of lentiviral vectors in serum‐free medium suspension cultures
Tiago André Gonçalves Vaz, Ana F. Rodrigues, Ana Sofia Coroadinha · 2023 · Biotechnology Journal
Selecting a Cell Engineering Methodology During Cell Therapy Product Development
Lauren M. Timmins, Alexandra Burr, Kristina Carroll, Robert Keefe, Matthew Teryek, L J Cantolupo, Johannes C.M. van der Loo, Thomas R.J. Heathman, Adam J. Gormley, David W. Smith et al. · 2021 · Cell Transplantation
A review of the underlying genetics and emerging therapies for canine cardiomyopathies
Leping Shen, Amara H. Estrada, Kathryn M. Meurs, M. Sleeper, Chris D. Vulpe, Christopher Joseph Martyniuk, Christina A. Pacak · 2021 · Journal of Veterinary Cardiology
Development of novel lipoplex formulation methodologies to improve large-scale transient transfection for lentiviral vector manufacture
Thomas Williams-Fegredo, Lee Davies, Carol Knevelman, Kyriacos A. Mitrophanous, James Miskin, Qasim A. Rafiq · 2024 · Molecular Therapy — Methods & Clinical Development
Retroviral Vector Technology for Gene Therapy: History, Current Landscape, and Future Prospects
Soumeya Ali Jaballah, Lizna Mohamed Ali, Mohammad Abdullah Jehad, Shaima Akhlaq, Tahir Aziz Rizvi, Farah Mustafa · 2025 · Journal of Molecular Biology
Enhancing recombinant protein and viral vector production in mammalian cells by targeting the YTHDF readers of N6‐methyladenosine in mRNA
Nga Thi Lao, Niall Barron · 2023 · Biotechnology Journal
Liter-scale manufacturing of shelf-stable plasmid DNA/PEI transfection particles for viral vector production
Yizong Hu, Brendan A. Eder, Jinghan Lin, Sixuan Li, Yining Zhu, Tza‐Huei Wang, Ting Guo, Hai‐Quan Mao · 2024 · Molecular Therapy — Methods & Clinical Development
Protection of Lymphocytes Against HIV using Lentivirus Vector Carrying a Combination of TRIM5α-HRH Genes and microRNA Against CCR5
Denis O. Omelchenko, Dina Viktorovna Glazkova, Elena Vladimirovna Bogoslovskaya, Ф. А. Урусов, Ю.А. Жогина, Г. М. Цыганова, German Alexandrovich Shipulin · 2018 · Molecular Biology
Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing
Leila Mekkaoui, Jose G. Tejerizo, Sara Abreu, Lydie Rubat, Aleksandra Nikoniuk, William Macmorland, Claire Horlock, Sofia Matsumoto, Sarah Williams, Koval Smith et al. · 2022 · Molecular Therapy — Methods & Clinical Development
Cancer Gene Therapy: Development and Production of Lentiviral Vectors for Gene Therapy
Ana Sofia Coroadinha · 2022 · Methods in molecular biology
Developing a process of lentivirus purification from recombinant fluids using peptide affinity ligands
Eduardo Barbieri, Gina N. Mollica, Sobhana Alekhya Sripada, Shrirarjun Shastry, Yuxuan Wu, Arianna Minzoni, William Kojo Smith, Elena Wüstenhagen, Annika Aldinger, Heiner Graalfs et al. · 2025 · Bioengineering & Translational Medicine
CAMTA1–PPP3CA–NFATc4 multi-protein complex mediates the resistance of colorectal cancer to oxaliplatin
Ruijun Pan, Zhou Zhang, Hongtao Jia, Junjun Ma, Chao Wu, Pei Xue, Wei Cai, Xiaoping Zhang, Jing Ping Sun · 2022 · Cell Death Discovery
Optimizing and developing a scalable, chemically defined, animal component-free lentiviral vector production process in a fixed-bed bioreactor
Carme Ripoll Fiol, Marie-Laure Collignon, John Welsh, Qasim A. Rafiq · 2023 · Molecular Therapy — Methods & Clinical Development
Stable Expression by Lentiviral Transduction of Cells
Natascha Gödecke, H. Häuser, Dagmar Wirth · 2018 · Methods in molecular biology
Generation of High-Titer Pseudotyped Lentiviral Vectors
Shuang Hu, Mingjie Li, Ramesh Akkina · 2019 · Methods in molecular biology
Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT
Pennapa Thongararm, Bogdan I. Fedeles, Sakunchai Khumsubdee, Amanda L. Armijo, Lina Kim, Apinya Thiantanawat, Jeerawan Promvijit, Panida Navasumrit, Mathuros Ruchirawat, Robert G. Croy et al. · 2019 · Chemical Research in Toxicology
Production of High-Titer Lentiviral Particles for Stable Genetic Modification of Mammalian Cells
Michael R. Larcombe, Jan Manent, Joseph Chen, Ketan Mishra, Xiaodong Liu, Christian Maximilian Nefzger · 2019 · Methods in molecular biology
Development of a laboratory scalable process for enhancing lentivirus production by transient transfection of HEK293 adherent cultures
Yoon Khei Ho, Heng‐Phon Too · 2020 · Gene Therapy
Engineering a Synthesis-Friendly Constitutive Promoter for Mammalian Cell Expression
Chee Ka Candice Lam, Kevin Truong · 2020 · ACS Synthetic Biology
Quasi-perfusion studies for intensified lentiviral vector production using a continuous stable producer cell line
Dale J. Stibbs, Pedro Silva Couto, Yasuhiro Takeuchi, Qasim A. Rafiq, Nigel B. Jackson, Andrea C. M. E. Rayat · 2024 · Molecular Therapy — Methods & Clinical Development
Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1
Shuo Wang, Xigong Li, Tianjiao Wang, Zeyu Sun, Erwei Feng, Yongming Jin · 2024 · Communications Biology
Challenges in lentiviral vector production: retro-transduction of producer cell lines
Maximilian Klimpel, Christin Obert, Monica Cristina Terrão, Parameswari Singh, Haiyan Wei, Chao‐Guang Chen, Andreas Gille, Silke Wissing, Holger Laux · 2025 · Frontiers in Bioengineering and Biotechnology
Membrane adsorber design for lentiviral vector recovery
George Pamenter, Danyal H Rahim, Ciaran M. Lamont, Maria Kapanidou, Kirstie Pemberton, Rui Sanches, Anurag Kulkarni, Oliver Charles Goodyear, Carol Knevelman, Kyriacos A. Mitrophanous et al. · 2025 · Molecular Therapy — Methods & Clinical Development
Challenges and Opportunities in Lentivirus Viral Vector Manufacturing for In Vivo Applications
Eduardo Barbieri, Caryn L. Heldt · 2026 · Biomedicines
Transition from serum-supplemented monolayer to serum-free suspension lentiviral vector production for generation of chimeric antigen receptor T cells
Mariane Cariati Tirapelle, Ana Luiza Oliveira Lomba, Renata Nacasaki Silvestre, Amanda Mizukami, Dimas Tadeu Covas, Virgínia Picanço‐Castro, Kamilla Swiech · 2022 · Cytotherapy
Efficient and simple genetic engineering of enteroids using mouse isolated crypts for investigating intestinal functions
Shuya Ohira, Yuki Yokoi, Tokiyoshi Ayabe, Kiminori Nakamura · 2022 · Biochemical and Biophysical Research Communications
Pseudotyped Viruses for Retroviruses
Magan Solomon, Chen Liang · 2023 · Advances in experimental medicine and biology
Overview of Current Downstream Processing for Modern Viral Vectors
Paul Cashen, Katy A. McLaughlin · 2023 · Springer eBooks
Uncertainty quantification for gene delivery methods: A roadmap for pDNA manufacturing from phase I clinical trials to commercialization
Niki Triantafyllou, Miriam Sarkis, Aikaterina Krassakopoulou, Nilay Shah, Maria M. Papathanasiou, Cleo Kontoravdi · 2023 · Biotechnology Journal
Chemo‐small extracellular vesicles released in cisplatin‐resistance ovarian cancer cells are regulated by the lysosomal function
Cristóbal Cerda‐Troncoso, Felipe Grünenwald, Eloísa Arias‐Muñoz, Viviana A. Cavieres, Albano Cáceres‐Verschae, Sergio Hernández, Belén Gaete‐Ramírez, Francisca Álvarez‐Astudillo, Rodrigo A. Acuña, Matías Ostrowski et al. · 2024 · Journal of Extracellular Biology
Scale-up of lentiviral vectors for gene therapy: advances and challenges
Alexandra McCarron, Martin Donnelley, David Parsons · 2017 · Cell and Gene Therapy Insights
In vivo CAR T cell generation using retargeted and functionalized lentiviral vectors with reduced immunogenicity
Kyrellos E. Ibrahim, Kepler S. Mears, Peter M. Allen, Jordan M. Chinai, Omar I. Avila, Audrey J. Muscato, Sarah Kate Lane-Reticker, Alexánder Rojas, Nelson H. Knudsen, Chun‐Cheih Chao et al. · 2026 · Nature Communications
An efficient low cost means of biophysical gene transfection in primary cells
Shudi Huang, Tyler R. Henderson, Chesarahmia Dojo Soeandy, Anastasiya Lezhanska, Jeffrey Theodore Henderson · 2024 · Scientific Reports
Non‐industrial production of therapeutic lentiviral vectors: How to provide vectors to academic CAR‐T
Viktoriya V. Keyer, Laura Syzdykova, Bakytkali Ingirbay, Elena S. Sedova, Gulzat Zauatbayeva, Tolganay Kulatay, Alexandr Shevtsov, Alexandr V. Shustov · 2024 · Biotechnology and Bioengineering
Investigating Ultrafiltration Membranes and Operation Modes for Improved Lentiviral Vector Processing
Jennifer J. Labisch, Maria Evangelopoulou, T. Schleuß, Andreas Pickl · 2025 · Engineering in Life Sciences
Viral Vectors for Gene Therapy
Clévio Nóbrega, Liliana S. Mendonça, Carlos A. Matos · 2020 · Springer eBooks
Gene-modified, cell-based therapies—an overview
Allison B. Powell, Kiara Williams, Carolina Colli Cruz · 2016 · Cytotherapy
Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury
Ciara Shortiss, Linda Howard, Siobhán S. McMahon · 2021 · Cells
Lentiviral Vector Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells
Aline Do Minh, Michelle Yen Tran, Amine Kamen · 2019 · Methods in molecular biology
Depth filtration for clarification of intensified lentiviral vector suspension cell culture
Mukesh Mayani, Srinivas Nellimarla, Ratish Mangalathillam, Hema Rao, Susannah L. Patarroyo-White, Junfen Ma, Bruno Figueroa · 2023 · Biotechnology Progress
Gene Delivery via Octadecylamine-Based Nanoparticles for iPSC Generation from CCD1072-SK Fibroblast Cells
Hanife Sevgi Varlı, Meryem Akkurt Yıldırım, Kadriye Kızılbey, Nelisa Türkoğlu Laçin · 2024 · Current Issues in Molecular Biology
Enhancing titers of therapeutic lentiviral vectors using PKC agonists
Charles Moore-Kelly, Rajesh Reddem, B. M. Alberts, Jordan Wright, T. Evans, Anurag Kulkarni, Nicholas G. Clarkson, D. Farley, K. Mitrophanous, Rui André Saraiva Raposo · 2025 · Molecular Therapy: Methods & Clinical Development
Serum-free lentiviral vector production is compatible with medium-resident nuclease activity arising from adherent HEK293T host cells engineered with a nuclease-encoding transgene
Sadfer Ali, Milena Rivera, John Maxim Ward, Eli Keshavarz‐Moore, Chris Mason, Darren Nesbeth · 2023 · Heliyon
Phase I/II Manufacture of Lentiviral Vectors Under GMP in an Academic Setting
Anindya Dasgupta, Stuart L. Tinch, Kathleen Szczur, Rebecca Ernst, Nathaniel Shryock, Courtney Kaylor, Kendall Lewis, Eric Day, Timmy Truong, William P. Swaney · 2019 · Methods in molecular biology
Identification of ADAR1 p150 and p110 Associated Edit Sites
Tony Sun, Brad R. Rosenberg, Hachung Chung, Charles M. Rice · 2023 · Methods in molecular biology
Production of Therapeutic Enzymes by Lentivirus Transgenesis
María Celeste Rodríguez, Natalia Ceaglio, Sebastián Antuña, María Belén Tardivo, Marina Etcheverrigaray, Claudio C. Prieto · 2019 · Advances in experimental medicine and biology
Real-time transfer of lentiviral particles by producer cells using an engineered coculture system
Lauren M. Timmins, Riya S. Patel, Matthew Teryek, Biju Parekkadan · 2019 · Cytotechnology
Development of Lentiviral Packaging Cells and Scale Up of Production to Meet the Growing Demand in Cell and Gene Therapy
Yasemin van Heuvel, Jörn Stitz · 2025 · Current Gene Therapy
A novel pseudotype derived of the canine distemper virus for adapter-mediated lentiviral transduction in vivo
Nora Winter, Carolin Kolbe, Shima Ferdos, Larissa Steiner, Nils Bartelsen, Dominik Lock, Fabian Engert, Boris Engels, Mario Assenmacher, Michael Schindler et al. · 2025 · Molecular Therapy — Methods & Clinical Development
Enhancing lentiviral production for WAS gene therapy: a comparative analysis of stable producer cell lines evaluating flatware system and adherent bioreactors in perfusion mode
Parameswari Singh, Nikki Indresh Lal, Monica Cristina Terrão, Sarah Schwingal, Martina Biserni, Florian Aeschimann, Andrea Strauch, Herbert Dersch, Angel Jaramillo, Andreas Gille et al. · 2025 · Frontiers in Bioengineering and Biotechnology
Nano-Bio Interfaces: Pioneering Targeted Approaches for Disease Treatment and Prevention
Dilpreet Singh · 2024 · Journal of Macromolecular Science Part B
High yield process for the production of active human α‐galactosidase a in CHO‐K1 cells through lentivirus transgenesis
María Celeste Rodríguez, Natalia Ceaglio, Sebastián Antuña, María Belén Tardivo, Marina Etcheverrigaray, Claudio C. Prieto · 2017 · Biotechnology Progress
A standard procedure for lentiviral‐mediated labeling of murine mesenchymal stromal cells in vitro
Ana‐Mihaela Lupan, Mihai Bogdan Preda, Alexandrina Burlacu · 2019 · Biotechnology and Applied Biochemistry
Advancing a rapid, high throughput screening platform for optimization of lentivirus production
Sneha Gopal, Adam Osborne, Lindsay A. Hock, Jill M. Zemianek, Kun Fang, Gretchen V. Gee, Ronit Ghosh, David McNally, Steven M. Cramer, Jonathan S. Dordick · 2021 · Biotechnology Journal
Effective Transduction of Brain Neurons with Lentiviral Vectors Purified via Ion-Exchange Chromatography
Elizaveta V. Shaburova, Dmitriy A. Lanshakov · 2021 · Applied Biochemistry and Microbiology
Hitching a Ride: Enhancing Nucleic Acid Delivery into Target Cells Through Nanoparticles
Alekhya Penumarthi, Preetam Basak, Peter M. Smooker, Ravi Shukla · 2020 · Environmental chemistry for a sustainable world
Packaging of Single-Stranded RNA in Viruses and Virus-Like Particles
Rees F. Garmann, William M. Gelbart · 2026 · Annual Review of Biochemistry
DC-targeting lentivectors for cancer immunotherapy
Ester Gea‐Mallorquí, Sarah Rowland‐Jones · 2023 · Immunotherapy Advances
Engineered CAR-T cells: An immunotherapeutic approach for cancer treatment and beyond
Purva Khodke, Bajarang Vasant Kumbhar · 2024 · Advances in protein chemistry and structural biology
Bioprocess Development and Bioreactor Scale-Up for the Production of Recombinant Lentiviral Viral Vectors in HEK293 Suspension Cell Culture
Julien Robitaille, Aziza P. Manceur, Anja Rodenbrock, Martin Loignon · 2024 · Biochemistry
The ecto-enzyme CD38 modulates CD4T cell immunometabolic responses and participates in HIV pathogenesis
Fernando Díaz-Basilio, Moises Vergara‐Mendoza, Jessica Romero-Rodríguez, Sharik Hernández-Rizo, Alejandro Escobedo‐Calvario, L. Leon-Fuentes, Santiago Pérez-Patrigeón, Akio Murakami-Ogasawara, María Gómez-Palacio, Gustavo Reyes‐Terán et al. · 2024 · Journal of Leukocyte Biology
Comprehensive untargeted lipidomic profiling of third generation lentiviral vectors and packaging cells
Joshua A Roberts, Elena Godbout, Jocelyn A. Menard, Christopher N. C. Boddy, Jean‐Simon Diallo, Jeffrey C. Smith · 2024 · Molecular Omics
Overcoming lentiviral delivery limitations in hard-to-transduce suspension cells for genome-wide CRISPR screening
Antonino Napoleone, Ivy Rose Sebastian, Federico De Marco, Alexander Molin, Mohamed Hussein, Lovro Kramer, Thomas Jostock, Thomas Kelly, Nicole Borth · 2026 · Molecular Therapy Advances
Foamy Virus Integrase in Development of Viral Vector for Gene Therapy
Jin‐Sun Kim, Ga‐Eun Lee, Cha‐Gyun Shin · 2020 · Journal of Microbiology and Biotechnology
Process for production of chimeric antigen receptor-transducing lentivirus particles using infection with replicon particles containing self-replicating RNAs
Laura Syzdykova, Gulzat Zauatbayeva, Viktoriya V. Keyer, Yerlan Ramanculov, Roman Arsienko, Alexandr V. Shustov · 2023 · Biochemical Engineering Journal
Anti-tumor Efficacy of CD19 CAR-T in a Raji B Cell Xenografted Mouse Model
Qian Xiao, Xiaolei Su · 2023 · BIO-PROTOCOL
PE-STOP: A versatile tool for installing nonsense substitutions amenable for precise reversion
Ziguo Song, Guiquan Zhang, Shuhong Huang, Yao Liu, Guanglei Li, Xianhui Zhou, Jiayuan Sun, Pengfei Gao, Yulin Chen, Xingxu Huang et al. · 2023 · Journal of Biological Chemistry
Present Situation of Viral Vector Manufacturing and Ways to Overcome Potential Barriers in View of the Routine Large Scale Production and Use of Viral Vectors
O-W Merten · 2017 · Current Trends in Biomedical Engineering & Biosciences
Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. V: Manufacture and quality control
Gil Cunha De Santis, Dante Mário Langhi, Andreza Feitoza, Alfredo Mendrone, José Mauro Kutner, Dimas Tadeu Covas, Samuel Campanelli Freitas Couto, Renato Cunha, Maristela Delgado Orellana, Silvia Renata Cornélio Parolin Rizzo · 2021 · Hematology Transfusion and Cell Therapy
Parallel CD19/CD20 CAR-Activated T-Cells Are More Effective for Refractory B-Cell Lymphoma In Vitro and In Vivo
Yuzhen Yin, Pengchao Zhang, Ling He, Xianling Guo, Hui Wang, Jun Li, Qing Xu · 2022 · Evidence-based Complementary and Alternative Medicine · Retracted
Improvement of De Novo Cholesterol Biosynthesis Efficiently Promotes the Production of Human Immunodeficiency Virus Type 1-Derived Lentiviral Vectors
Nathalie Holic, Sophie Frin, Ababacar K. Seye, Anne H. M. Galy, David Fenard · 2017 · Human Gene Therapy Methods