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DNA Damage Signaling Downstream of ATM

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Cell Cycle and DNA Damage Response in Postmitotic Neurons

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DNA Repair and Cell Cycle Regulation After Ionizing Irradiation

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Non homologous end joining-mediated DNA break repair is impaired in B lymphocytes of aging mice

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Insight into the DNA repair mechanism operating during cell cycle checkpoints in eukaryotic cells

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DNA Damage and Repair in the Brain: Implications for Seizure-Induced Neuronal Injury, Endangerment, and Neuroprotection

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Triple-negative breast cancer

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Diverse Dealings of the Werner Helicase/Nuclease

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Establishment of a Cell-Free System to Study the Activation of Chk2

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Mechanisms of genome instability in Hutchinson-Gilford progeria

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SRSF3-TRIM28-MDC1 prevents DNA damage caused by R-loops in fatty liver disease in mice

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Cell Cycle, DNA Replication, Centrosomes, Centrioles and Cell Division

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Livin Regulates H2A.XY142 Phosphorylation and Promotes Autophagy in Colon Cancer Cells via a Novel Kinase Activity

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BRCA1 and BRCA2 Mutations - Diagnostic and Therapeutic Implications

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Chromatin-Associated SIN3B Protects Cancer Cells from Genotoxic Stress-Induced Apoptosis and Dictates DNA Damage Repair Pathway Choice

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RNF126, 168 and CUL1: The Potential Utilization of Multi-Functional E3 Ubiquitin Ligases in Genome Maintenance for Cancer Therapy

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Fusion of histone variants to Cas9 suppresses non-homologous end joining

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Dimerization, but not phosphothreonine binding, is conserved between the forkhead‐associated domains of Drosophila MU2 and human MDC1

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Expression, fermentation and purification of a predicted intrinsically disordered region of the transcription factor, NFAT5

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The Fanconi Anemia Pathway and Interstrand Cross-Link Repair

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Localization of the kinase Ataxia Telangiectasia Mutated to Adenovirus E4 mutant DNA replication centers is important for its inhibitory effect on viral DNA accumulation

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The impact of TP53BP1 and MLH1 on metastatic capability in cases of locally advanced prostate cancer and their usefulness in clinical practice

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Structure and Function of Rad50/SMC Protein Complexes in Chromosome Biology

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Megabase-scale detachment of genome-nuclear lamina interactions is required for efficient repair of double stranded breaksPreprint

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Slx4 and Fun30/SMARCAD1 coordinate S-phase checkpoint regulation and replication fork protection in response to Top1–DNA crosslinks

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Novel Variants in MDC1 are Associated With Severe Oligoasthenoteratozoospermia

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TIPIN coordinates ATM-dependent checkpoint and NF-κB signaling to counteract DNA replication damage from topoisomerase inhibition

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Cell cycle-related biomarker lineage promotes the malignant progression of recurrent IDH wild-type glioma

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Somatic-germline cross talk coordinates sexual differentiation in an oyster with sexual plasticity

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The Cell Biology of Mitotic Recombination in Saccharomyces Cerevisiae

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ROLE OF γ-H2AX IN DNA-DAMAGE RESPONSE AND ITS POSSIBLE CLINICAL APPLICATIONS

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Exploring ATM and Methylation in Cancer: Emphasizing on Brain Tumors

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Evelyn Witkin and Stephen Elledge share the 2015 Lasker Basic Medical Award

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Checkpoint Control Following Radiation Exposure

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DNA Damage Foci on Metaphase Chromosomes

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DNA Damage: Sensing

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Targeting ATM/ATR in the DNA Damage Checkpoint

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Regulatory network nodes of check point factors in DNA repair pathways

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Chromatin: The Entry to and Exit from DNA Repair

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A novel role of DNA fragmentation factor as a tumor suppressor through maintaining genomic stability

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Chapter 3

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Chromatin Modifications and Orchestration of Checkpoint Response in Cancer

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O papel da proteína SET no perfil de metilação do miR-9 e no reparo de DNA em células humanas de carcinoma espinocelular oral

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CHK2 is Negatively Regulated by Protein Phosphatase 2A

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Implications of BRCA1 mutations in basal-like breast cancer development and treatment

Gu, Y. (2015) · Työväentutkimus Vuosikirja

Roles of Homologous Recombination in Processing DNA Lesions

Tafel, A. A. (2007) · RePub (Erasmus University Rotterdam)

Double Strand Break Signaling in Health and Diseases

Halaby, M., & Hakem, R. (2011) · InTech eBooks · doi:10.5772/22148

O-GlcNAc Misregulation and Aneuploidy in Breast Cancer

Mueller, A. C. (2009) · Defense Technical Information Center (DTIC) · doi:10.21236/ada506322

ATM Deficiency -- A Multifaceted Defect in Lymphocyte Development

Helmink, B. A. (2012) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7k07291

Involvement of Histone PTMs in DNA Repair Processes in Relation to Age-Associated Neurodegenerative Disease

Wang, C., Pi, E., Zhan, Q., & Ngai, S. M. (2011) · InTech eBooks · doi:10.5772/22225

A Proteomic Approach to Identify Phosphorylation-Dependent Targets of BRCT Domains

Songyang, Z. (2006) · Defense Technical Information Center (DTIC) · doi:10.21236/ada458980

Regulation of cellular signalling pathways by Adenovirus

Forrester, N. A. (2012) · University of Birmingham Institutional Research Archive (University of Birmingham)

A New Pathway Responsible For 53BP1 Loss in Breast Cancer and Laminopathies

Grotsky, D. A. (2012) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7s180hg

Drugs, Genomic Response Signatures, and Customized Cancer Therapy

Rosell, R., Morán, T., & Tarón, M. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9781139021500.028

A theoretical investigation of protein recruitment during the DNA damage response and of the dynamics of DNA replication

Löb, D. (2013) · Technischen Universität Darmstadt · doi:10.26083/tuprints-00003556

Modifying the function of DNA repair nanomachines for therapeutic benefit

Dynan, W. S., Takeda, Y., & Li, S. (2006) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2006.04.004

Growth of IR-induced foci and G1 checkpoint

Yamauchi, M., Suzuki, K., Kodama, S., & Watanabe, M. (2007) · International Congress Series · doi:10.1016/j.ics.2006.10.016

Investigating the role of the JAK/STAT and MAPK pathways in ischaemia/reperfusion injury and inflammation

Barry, S. P. (2009) · UCL Discovery (University College London)

Effect of nucleotide binding on Rad50 conformational state, multimeric state, and DNA binding ability

Estrin, E. (2017) · Texas ScholarWorks (Texas Digital Library) · doi:10.15781/t2f766p45

p53 and DNA damage checkpoint responses in the human prostate

af Hällström, T. (2007)

LIF Insensitivity and Expression of Proteins Activated by DNA Damage Response in Teratoma-Isolated Cells Derived from Mouse Embryonic Stem Cells

Santana, A., Vicente-Salar, N., Freire, R., Reig, J. A., & Roche, E. (2013) · CYTOLOGIA · doi:10.1508/cytologia.78.195

ROLE OF LATENT EBV GENES IN THE INDUCTION OF GENOMIC INSTABILITY IN BURKITT'S LYMPHOMA

Gruhne, B. (2009) · Figshare

Protein Dynamics in Mammalian Genome Maintenance

Zotter, A. (2008) · RePub (Erasmus University Rotterdam)

Characterization of the mechanisms of ATM activation by the MRN complex and DNA

Lee, J. H. (2005) · Texas ScholarWorks (Texas Digital Library)

Cell Cycle: Regulation

McAndrew, C. W., Gastwirt, R. F., & Donoghue, D. J. (2008) · Wiley eBooks · doi:10.1002/9780470048672.wecb057

Mechanisms that control the growth of cells in the presence of replication stress

Pascual, Á. M. (2013) · e_Buah

The identification of novel methylated proteins in DNA damage response

Salim, A. (2010) · doi:10.82308/40431

ROLE OF TYROSYL-DNA PHOSPHODIESTERAS E (TDP 1) ON REPAIR

Compass, V. S. (2012)

Ubiquitination — An Evolving Role in DNA Repair

Boutou, E., Louka, M. A., Pappa, V., Stürzbecher, H.-W., Knippschild, U., Vlachodimitropoulos, D. G., & Vorgias, C. E. (2015) · InTech eBooks · doi:10.5772/61582

Diagnostic, Prognostic, and Therapeutic Value of Gene Signatures in Non-Small Cell Lung Cancer

Rosell, R., Tarón, M., Rolfo, C. D., Rodríguez‐Abreu, D., & Wei, J. (2011) · Humana Press eBooks · doi:10.1007/978-1-61779-358-5_6

Characterisation of the human DNA damage response and replication protein Topoisomerase IIβ Binding Protein 1 (TopBP1)

Reini, K. (2006)

Aberrations of DNA Damage in Checkpoints in Cancer

Laiho, M. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-200-7_5

DNA damage signaling in response to etoposide

Siponen, M. I. (2005) · Libraries and Cultural Resources (University of Calgary) · doi:10.11575/prism/17380

Selective targeting of cancer cells through inhibition of Checkpoint kinase 1

Hasvold, G. (2012) · NORA - Norwegian Open Research Archives

Distribution and dynamics of charged particle-induced DNA double-strand breaks

Splinter, J. (2010) · GSI Repository (German Federal Government) · doi:10.26083/tuprints-00002228

Defining a role for TPX2 in the nucleus – Regulation of the DNA damage response

Neumayer, G. (2013) · Libraries and Cultural Resources (University of Calgary) · doi:10.5072/prism/25537

Live-cell visualisation of chromatin for the study of radiation-induced chromosome aberrations

Malis, G. (2011) · Brunel University Research Archive (BURA) (Brunel University London)

Nachweis geringer strahleninduzierter DNA-Schäden mittels automatisierter Quantifizierung von γH2AX

Stangassinger, M., Physiologie, L. F., & München, L.-M.-U. (2009)

Enzyme and Protein Families that Regulate Histone Modifications and Crosstalk

Rutledge, C. E., & Turner, B. M. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781782628484-00020

Analysis of cell cycle’s correlation of γ-H2AX

Yue, Y., Zhu, Z., Yu, D., Deng, Y., Huang, D., Li, X., Xiao, W., Tao, D., Hu, J., & Gong, J. (2008) · The Chinese-German Journal of Clinical Oncology · doi:10.1007/s10330-008-0093-0

DNA Repair during Class Switch Recombination

Ramachandran, S., & Martín, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-374279-7.05016-5

Analysis of the epigenetics of meiotic silencing and its role in germ cell loss

Cloutier, J. M. (2016) · UCL Discovery (University College London)

Histone c-H2AX Involvement in DNA Double-Strand Break Repair Pathways

Rogakou, N. A. A. B. A. E. P. (2005) · doi:10.1201/9780849352683-41

Chapter 6 Chromatin Modifications and Orchestration of Checkpoint Response in Cancer

Nakanishi, M. (2009)

Discovery of Small Molecule and Peptide-based Ligands for the Methyl-Lysine Binding Proteins 53BP1 and PHF1/PHF19

Perfetti, M. T. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/r5bz-a487

The interaction between Rad9 and Tousled-like kinase 1 in the cell cycle and the DNA damage response

Kelly, R. M. (2013) · QSpace (Queen's University Library)

DEVELOPMENT OF A FUNCTIONAL ASSAY FOR DETERMINATION OF BRCA1 CARRIER STATUS

Bathurst, L. (2014) · QSpace (Queen's University Library)

Mediator of damage checkpoint

Weitzman, J. B. (2003) · Genome biology · doi:10.1186/gb-spotlight-20030303-01

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

Stucki, M., & Jackson, S. P. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.03.007 · Cited by 113

MDC1 is required for the intra-S-phase DNA damage checkpoint

Goldberg, M., Stucki, M., Falck, J., D'Amours, D., Rahman, D., Pappin, D., Bartek, J., & Jackson, S. P. (2003) · Nature · doi:10.1038/nature01445 · Cited by 506

Mediator of DNA Damage Checkpoint Protein 1 Regulates BRCA1 Localization and Phosphorylation in DNA Damage Checkpoint Control

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MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

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