The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
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Citations
Cites
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., et al. (1999) · Science · doi:10.1126/science.286.5440.735 · Cited by 3,876 · cited 1×
“In support of this conclusion: (1) lithium reduces Ab production in cultured cells and in the brains of mice that overproduce Ab peptides; (2) kenpaullone, an alternative GSK-3a inhibitor, also inhibits Ab production; (3) RNAi-mediated depletion of GSK-3a reduces Ab production; and (4) moderate overexpression of GSK-3…”
ResultDeficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., & Van Leuven, F. (1998) · Nature · doi:10.1038/34910 · Cited by 1,818
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
Weggen, S., Eriksen, J. L., Das, P., Sagi, S. A., Wang, R., Pietrzik, C. U., Findlay, K. A., Smith, T. E., Murphy, M. P., Bulter, T., et al. (2001) · Nature · doi:10.1038/35102591 · Cited by 1,388
The specificities of protein kinase inhibitors: an update
BAIN, J., McLAUCHLAN, H., ELLIOTT, M., & COHEN, P. (2003) · Biochemical Journal · doi:10.1042/bj20021535 · Cited by 1,369 · cited 1×
“To test the hypothesis that lithium reduces Aβ production through inhibition of GSK-3, we treated CHO-APP 695 cells with the structurally unrelated GSK-3 inhibitor kenpaullon”
MethodSiman, R., Reaume, A. G., Savage, M. J., Trusko, S., Lin, Y.-G., Scott, R. W., & Flood, D. G. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-23-08717.2000 · Cited by 133
Cited by
Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders
Ballatore, C., Lee, V. M.-Y., & Trojanowski, J. Q. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2194 · Cited by 2,174
Self-citationGlycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Beurel, E., Grieco, S. F., & Jope, R. S. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.11.016 · Cited by 1,768
WNT and β-catenin signalling: diseases and therapies
Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1427 · Cited by 1,763
Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics
Tiwari, S., Atluri, V., Kaushik, A., Yndart, A., & Nair, M. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s200490 · Cited by 1,308
Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo
Cirrito, J. R., Yamada, K. A., Finn, M. B., Sloviter, R. S., Bales, K. R., May, P. C., Schoepp, D. D., Paul, S. M., Mennerick, S., & Holtzman, D. M. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.028 · Cited by 1,265
Metadata
- Authors
- Phiel, C. J., Wilson, C. A., Lee, V. M.-Y., & Klein, P. S.
- Venue
- Nature
- Published
- 2003-05
- Volume
- 423
- Issue
- 6938
- Pages
- 435-439
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1567624342
- Cited by
- 1,196
- References
- 5
- FWCI
- 36.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: GSK-3α regulates production of Alzheimer's disease amyloid-β peptides. https://app.cochat.ai/papers/10.1038/nature01640
- The paper
- Phiel, C. J., Wilson, C. A., Lee, V. M.-Y., & Klein, P. S. (2003). GSK-3α regulates production of Alzheimer's disease amyloid-β peptides. Nature. https://doi.org/10.1038/nature01640
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
