Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Baines, Christopher P., Kaiser, Robert A., Purcell, Nicole H., Blair, N. Scott, Osinska, Hanna, Hambleton, Michael A., Brunskill, Eric W., Sayen, M. Richard, Gottlieb, Roberta A., Dorn, Gerald W., Robbins, Jeffrey, Molkentin, Jeffery D.·2005·Nature
DOI 10.1038/nature03434

Cited by (1,002)

Items 801–900 of 1,002

  1. Mitochondrial Flash: Integrative Reactive Oxygen Species and pH Signals in Cell and Organelle Biology
    Wang Wang, Guohua Gong, Xianhua Wang, Lan Wei‐LaPierre, Heping Cheng, Robert T. Dirksen, Shey‐Shing Sheu · 2016 · Antioxidants and Redox Signaling
  2. Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis
    Zheng Yang, Chen Li, Yishi Wang, Jingrun Yang, Yue Yin, Manling Liu, Zhaoling Shi, Nan Mu, Lu Yu, Heng Ma · 2018 · Journal of Molecular and Cellular Cardiology
  3. Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming
    Zhongfu Ying, Ge Xiang, Lingjun Zheng, Haite Tang, Lifan Duan, Xiaobing Lin, Qiuge Zhao, Keshi Chen, Yi Wu, Guangsuo Xing et al. · 2018 · Cell Metabolism
  4. Regulation of cell death in the cardiovascular system
    Pooja Patel, Jason M. Karch · 2019 · International review of cytology
  5. Necroptosis: A Pathogenic Negotiator in Human Diseases
    Hitesh Singh Chaouhan, Ch. Vinod, Nikita Mahapatra, Shaohua Yu, I‐Kuan Wang, Kuen‐Bao Chen, Tung‐Min Yu, Chi‐Yuan Li · 2022 · International Journal of Molecular Sciences
  6. Pretreatment with the Cyclosporin Derivative, NIM811, Improves the Function of Synaptic Mitochondria following Spinal Cord Contusion in Rats
    Melanie L. McEwen, Patrick G. Sullivan, Joe E. Springer · 2007 · Journal of Neurotrauma
  7. Removal of H2O2 and generation of superoxide radical: Role of cytochrome c and NADH
    Murugesan Velayutham, Craig F. Hemann, Jay Louis Zweier · 2011 · Free Radical Biology and Medicine
  8. Cyclophilin D Modulates Mitochondrial Acetylome
    Tiffany Tuyen Minh Nguyen, Renee P. Wong, Sara Menazza, Junhui Sun, Yong Chen, Guanghui Wang, Marjan Guček, Charles Steenbergen, Michael N. Sack, Elizabeth Murphy · 2013 · Circulation Research
  9. Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle
    Irina A. Kramerova, Elena Kudryashova, Benjamin G. Wu, Sean A. Germain, Krista Vandenborne, Nadine Romain, Ronald G. Haller, M. Anthony Verity, Melissa J. Spencer · 2009 · Human Molecular Genetics
  10. Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis
    Jack J. J. J. Miller, Angus Z. Lau, Per Mose Nielsen, Giles McMullen-Klein, Andrew J. Lewis, Nichlas Riise Jespersen, Vicky Ball, Ferdia Aidan Gallagher, Carolyn A. Carr, Christoffer Laustsen et al. · 2017 · JACC. Cardiovascular imaging
  11. Mitochondrial factors with dual roles in death and survival
    W-C Cheng, Sarah Berman, Irena Lambrova Ivanovska, Ernesto A. Jonas, SoJung Lee, Yongqiang Chen, Leonard K. Kaczmarek, Fernando J. Pineda, J. Marie Hardwick · 2006 · Oncogene
  12. The end-effectors of preconditioning protection against myocardial cell death secondary to ischemia–reperfusion
    D GARCIADORADO, Antonio Rodríguez‐Sinovas, Marisol Ruiz‐Meana, Javier Inserte, Luís Agulló, Alberto Cabestrero · 2006 · Cardiovascular Research
  13. Regulation of calcium homeostasis in endoplasmic reticulum-mitochondria crosstalk: Implications for skeletal muscle atrophy
    Li, Xuexin, Zhao, Xin, Qin, Zhengshan, Li, Jie, Sun, Bowen, Liu, Li · 2025 · Cell Communication and Signaling
  14. Nuclear-encoded mitochondrial proteins and their role in cardioprotection
    Boengler, Kerstin, Heusch, Gerd, Schulz, Rainer · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  15. Dynamics of the mitochondrial permeability transition pore: Transient and permanent opening events
    Boyman, Liron, Coleman, Andrew K., Zhao, Guiling, Wescott, Andrew P., Joca, Humberto C., Greiser, B. Maura, Karbowski, Mariusz, Ward, Chris W., Lederer, W.J. · 2019 · Archives of Biochemistry and Biophysics
  16. Role of Endoplasmic Reticulum Stress in Atherosclerosis and Its Potential as a Therapeutic Target
    Shengjie Yang, Min Wu, Xiaoya Li, Ran Zhao, Yixi Zhao, Longtao Liu, Songzi Wang · 2020 · Oxidative Medicine and Cellular Longevity
  17. Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
    Byoung Heon Kang, Michele Tavecchio, Hira Lal Goel, C-C Hsieh, David S. Garlick, Christopher M. Raskett, Jane B. Lian, Gary S. Stein, Lucia R. Languino, Dario C. Altieri · 2011 · British Journal of Cancer
  18. Lithium Desensitizes Brain Mitochondria to Calcium, Antagonizes Permeability Transition, and Diminishes Cytochrome c Release
    Natalia Shalbuyeva, Tatiana Brustovetsky, Nickolay Brustovetsky · 2007 · Journal of Biological Chemistry
  19. Molecular Basis of Cardioprotective Effect of Antioxidant Vitamins in Myocardial Infarction
    Ramón Rodrigo, Matías Libuy, Felipe Feliú, Daniel Hasson · 2013 · BioMed Research International
  20. Muscle denervation promotes opening of the permeability transition pore and increases the expression of cyclophilin D
    Kristina Csukly, Alexis Ascah, Jimmy Matas, Phillip F. Gardiner, Eric M. Fontaine, Yan Burelle · 2006 · The Journal of Physiology
  21. Cyclosporine in acute ischemic stroke
    Norbert Nighoghossian, Yves Berthezène, Laura Mechtouff, Laurent Derex, Tae‐Hee Cho, Thomas Ritzenthaler, Sylvain Rheims, Fabien Chauveau, Yannick Béjot, Agnès Jacquin et al. · 2015 · Neurology
  22. Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis
    Emma R. Shore, Muhammad Awais, Neil M. Kershaw, Robert R. Gibson, Sravan R. Pandalaneni, Diane Latawiec, Wen Li, Muhammad Ahsan Javed, David Neil Criddle, Neil G. Berry et al. · 2016 · Journal of Medicinal Chemistry
  23. Mycobacterium abscessus glycopeptidolipids inhibit macrophage apoptosis and bacterial spreading by targeting mitochondrial cyclophilin D
    Jake Whang, Yong Woo Back, Kang-In Lee, Nagatoshi Fujiwara, Seungwha Paik, Chul Hee Choi, Jeong‐Kyu Park, Hwa‐Jung Kim · 2017 · Cell Death and Disease
  24. Mechanistic connections between mitochondrial biology and regulated cell death
    Jerry E. Chipuk, Jarvier N. Mohammed, Jesse D. Gelles, Yiyang Chen · 2021 · Developmental Cell
  25. The molecular identity of the mitochondrial Ca2+ sequestration system
    Anatoly A. Starkov · 2010 · FEBS Journal
  26. Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure
    Shiang Yong Lim, Derek John Hausenloy, Sapna Arjun, Anthony N. Price, Sean M. Davidson, Mark F. Lythgoe, Derek M. Yellon · 2010 · Journal of Cellular and Molecular Medicine
  27. The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia
    Marisol Ruiz‐Meana, Javier Inserte, Celia Fernández‐Sanz, Victor García-Hernando, Elisabet Miró‐Casas, Ignasi Barba, David Garcia-dorado A · 2011 · Basic Research in Cardiology
  28. The Mitochondrial Permeability Transition Regulates Cytochrome c Release for Apoptosis during Endoplasmic Reticulum Stress by Remodeling the Cristae Junction
    Dawei Zhang, Chao Lü, Matthew Whiteman, Britton Chance, Jeffrey S. Armstrong · 2007 · Journal of Biological Chemistry
  29. The consequences of mitochondrial amyloid β-peptide in Alzheimer's disease
    Kirsty E. A. Muirhead, Eva Borger, Laura Aitken, Stuart J. Conway, Frank J. Gunn‐Moore · 2010 · Biochemical Journal
  30. Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria after Traumatic Brain Injury and Are Protected by Cyclosporine A
    Jacqueline Renee Kulbe, Rachel L. Hill, Indrapal N. Singh, Juan A. Wang, Edward D. Hall · 2016 · Journal of Neurotrauma
  31. Excitotoxins, Mitochondrial and Redox Disturbances in Multiple Sclerosis
    Cecília Rajda, Dániel Pukoli, Zsuzsanna Bende, Zsófia Majláth, László Vécsei · 2017 · International Journal of Molecular Sciences
  32. Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo
    Moua Yang, Andaleb Kholmukhamedov, Marie L. Schulte, Brian C. Cooley, Na’il O. Scoggins, Jeremy P. Wood, Scott J. Cameron, Craig N. Morrell, Shawn M. Jobe, Roy L. Silverstein · 2018 · Blood Advances
  33. High Sensitivity of SIRT3 Deficient Hearts to Ischemia-Reperfusion Is Associated with Mitochondrial Abnormalities
    Rebecca Maria Parodi‐Rullán, Xavier R. Chapa‐Dubocq, Pedro J. Rullán, Sehwan Jang, Sabzali A. Javadov · 2017 · Frontiers in Pharmacology
  34. Endurance training reverts heart mitochondrial dysfunction.; permeability transition and apoptotic signaling in long-term severe hyperglycemia
    Lumini-Oliveira, José, Magalhães, José, Pereira, Cláudia V., Moreira, Ana C., Oliveira, Paulo J., Ascensão, António · 2011 · Mitochondrion
  35. Excitotoxicity Revisited: Mitochondria on the Verge of a Nervous Breakdown
    Nicoletta Plotegher, Riccardo Filadi, Paola Pizzo, Michael R. Duchen · 2021 · Trends in Neurosciences
  36. Necroptosis in heart disease: Molecular mechanisms and therapeutic implications
    Xiaoyun Guo, Yi Chen, Qinghang Liu · 2022 · Journal of Molecular and Cellular Cardiology
  37. Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS
    Kin Lung Siu, Christopher Lotz, Peipei Ping, Hua “Linda” Cai · 2014 · Journal of Molecular and Cellular Cardiology
  38. Mitochondrial Peroxiredoxin III is a Potential Target for Cancer Therapy
    In-Sung Song, Hyoung-Kyu Kim, Seung-Hun Jeong, Sungryul Lee, Nari Kim, Byoung Doo Rhee, Kyung Soo Ko, Jin Han · 2011 · International Journal of Molecular Sciences
  39. IP3, a small molecule with a powerful message
    Elke Decrock, Marijke De Bock, Nan Wang, Ashish Kumar Gadicherla, Mélissa Bol, Tinneke Delvaeye, Peter Vandenabeele, Mathieu Vinken, Geert Bultynck, Dmitri V. Krysko et al. · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  40. The Potential Role of Mitochondria in Pediatric Traumatic Brain Injury
    Courtney Robertson, Lucian Soane, Zachary Timothy Glynn Siegel, Gary M. Fiskum · 2006 · Developmental Neuroscience
  41. Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis
    Fanny Tzelepis, Julianna Blagih, Nargis Khan, Joshua Gillard, Laura Mendonca, Dominic Guy Roy, Eric H. Ma, Philippe Joubert, Russell G. Jones, Maziar Divangahi · 2018 · Science Immunology
  42. Activation of Mitochondrial Calcium-independent Phospholipase A2γ (iPLA2γ) by Divalent Cations Mediating Arachidonate Release and Production of Downstream Eicosanoids
    Sung Ho Moon, Christopher M. Jenkins, Xinping Liu, Shaoping Guan, David J. Mancuso, Richard W. Gross · 2012 · Journal of Biological Chemistry
  43. The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging
    Michael N. Sack · 2011 · Journal of Molecular and Cellular Cardiology
  44. The Oligomycin-Sensitivity Conferring Protein of Mitochondrial ATP Synthase: Emerging New Roles in Mitochondrial Pathophysiology
    Manuela Antoniel, Valentina Giorgio, Federico Fogolari, Gary D. Glick, Paolo Bernardi, Giovanna Lippe · 2014 · International Journal of Molecular Sciences
  45. A Mitochondriotropic Derivative of Quercetin: A Strategy to Increase the Effectiveness of Polyphenols
    Andrea Mattarei, Lucia Biasutto, Ester Marotta, Umberto De Marchi, Nicola Sassi A, Spiridione Garbisa, Mario Zoratti, Cristina Paradisi · 2008 · ChemBioChem
  46. Necroptosis: Who Knew There were so Many Interesting Ways to Die?
    S. M. Fayaz, V. S. Suvanish Kumar, Golgodu Krishnamurthy Rajanikant · 2014 · CNS & Neurological Disorders - Drug Targets
  47. Activation of mitochondrial calpain and increased cardiac injury: beyond AIF release
    Jeremy Thompson, Ying Hu, Edward Joseph Lesnefsky, Qun Chen · 2015 · American Journal of Physiology-Heart and Circulatory Physiology
  48. Sevoflurane preconditioning improves mitochondrial function and long-term neurologic sequelae after transient cerebral ischemia
    Ruidong Ye, Qianzi Yang, Xiangwei Kong, Nanlin Li, Yunxia Zhang, Junliang Han, Lize Xiong, Xinfeng Liu, Gang Zhao · 2012 · Critical Care Medicine
  49. Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis
    Xiaolei Wang, Heng Du, Shanshan Shao, Tao Bo, Chunxiao Yu, Wenbin Chen, Lifang Zhao, Qiu Li, Li Wang, Xiaojing Liu et al. · 2018 · Hepatology
  50. Cryopreservation induces mitochondrial permeability transition in a bovine sperm model
    F. Treulen, María Elena Arias, Luis Águila, Pamela Uribe, Ricardo N. Felmer · 2018 · Cryobiology
  51. Non-Thermal Atmospheric Pressure Bio-Compatible Plasma Stimulates Apoptosis via p38/MAPK Mechanism in U87 Malignant Glioblastoma
    Mahmuda Akter, Anshika Jangra, Seung Ah Choi, Eun Ha Choi, Ihn Han · 2020 · Cancers
  52. Purinergic Receptor-Stimulated IP3-Mediated Ca2+ Release Enhances Neuroprotection by Increasing Astrocyte Mitochondrial Metabolism during Aging
    Jun Wu, J. D. Holstein, G. Upadhyay, Da‐Ting Lin, Stuart J. Conway, E. Muller, James Donald Lechleiter · 2007 · Journal of Neuroscience
  53. The RISK pathway leading to mitochondria and cardioprotection: how everything started
    Derek M. Yellon, Siavash Beikoghli Kalkhoran, Sean M. Davidson · 2023 · Basic Research in Cardiology
  54. Regulation of mitochondrial ATP synthase in cardiac pathophysiology.
    Qinqiang Long, Kevin Yang, Qinglin Yang · 2015 · Europe PMC (PubMed Central)
  55. Blockade of electron transport during ischemia preserves bcl-2 and inhibits opening of the mitochondrial permeability transition pore
    Qun Chen, Edward Joseph Lesnefsky · 2011 · FEBS Letters
  56. What makes the mitochondria a killer? Can we condition them to be less destructive?
    Elizabeth Murphy, Charles Steenbergen · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  57. Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96‐Å resolution
    Kenji Kajitani, Masahiro Fujihashi, Yukiko Kobayashi, Shigeomi Shimizu, Yoshihide Tsujimoto, Kunio Miki · 2007 · Proteins Structure Function and Bioinformatics
  58. Dual Modulation of the Mitochondrial Permeability Transition Pore and Redox Signaling Synergistically Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells
    Sung Woo Cho, Jin‐Sung Park, Hye Jin Heo, Sang‐Wook Park, Sukhyun Song, Injune Kim, Yong‐Mahn Han, Jun K. Yamashita, Jae Boum Youm, Jin Han et al. · 2014 · Journal of the American Heart Association
  59. Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition
    Tiffany Greco, Gary M. Fiskum · 2010 · Journal of Bioenergetics and Biomembranes
  60. Superoxide flashes: Elemental events of mitochondrial ROS signaling in the heart
    Xianhua Wang, Chongshu Jian, Xing Zhang, Zhanglong Huang, Jiejia Xu, Tingting Hou, Wei H. Shang, Yi Ding, Wanrui Zhang, Meng Ouyang et al. · 2012 · Journal of Molecular and Cellular Cardiology
  61. Bovine lactoferrin regulates cell survival, apoptosis and inflammation in intestinal epithelial cells and preterm pig intestine
    Duc Ninh Nguyen, Pingping Jiang, Allan Stensballe, Emöke Bendixen, Per Torp Sangild, Dereck E. W. Chatterton · 2016 · Journal of Proteomics
  62. Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin
    Giuseppe Paradies, Valeria Paradies, Francesca Maria Ruggiero, Giuseppe Petrosillo · 2017 · Cellular and Molecular Life Sciences
  63. Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond
    Junxia Zhang, Dairu Liu, Mao Zhang, Yan Zhang · 2018 · British Journal of Pharmacology
  64. The Role of the Mitochondrial Apoptosis Induced Channel MAC in Cytochrome c Release
    Sonia Martinez‐Caballero, Laurent M. Dejean, Elizabeth Ann Jonas, Kathleen Walsh Kinnally · 2005 · Journal of Bioenergetics and Biomembranes
  65. Programmed cell death in cardiac myocytes: strategies to maximize post-ischemic salvage
    Kartik M. Mani · 2008 · Heart Failure Reviews
  66. Intertwined pathways of programmed cell death in immunity
    Stephen Μ. Hedrick, Irene L. Ch’en, Bryce N. Alves · 2010 · Immunological Reviews
  67. Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening
    Jyotsna Mishra, Ariea J Davani, Gayathri K. Natarajan, Wai‐Meng Kwok, David F. Stowe, Amadou K.S. Camara · 2019 · Cells
  68. Chapter 16 Novel Methods for Measuring Cardiac Autophagy In Vivo
    Cynthia N. Perry, Shiori Kyoi, Nirmala Hariharan, Hiromitsu Takagi, Junichi Sadoshima, Roberta A. Gottlieb · 2009 · Methods in enzymology on CD-ROM/Methods in enzymology
  69. Induction of the permeability transition and cytochrome c release by 15-deoxy-Δ12,14-prostaglandin J2 in mitochondria
    Aimee L. Landar, Sruti Shiva, Anna–Liisa Levonen, Joo‐Yeun Oh, Corinne Zaragoza, Michelle Smith Johnson, Victor M. Darley-Usmar · 2006 · Biochemical Journal
  70. Considering effects of nanosecond pulsed electric fields on proteins
    Stephen J. Beebe · 2014 · Bioelectrochemistry
  71. Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart
    Michael N. Sack · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
  72. Pharmacological strategies against cold ischemia reperfusion injury
    Mohamed Amine Zaoualí, Hassen Ben Abdennebi, Susagna Padrissa‐Altés, Asma Mahfoudh-Boussaid, Joan Roselló‐Catafau · 2010 · Expert Opinion on Pharmacotherapy
  73. Low-intensity aerobic interval training attenuates pathological left ventricular remodeling and mitochondrial dysfunction in aortic-banded miniature swine
    Craig A. Emter, Christopher P. Baines · 2010 · American Journal of Physiology-Heart and Circulatory Physiology
  74. Central role of mitochondrial injury in the pathogenesis of acute pancreatitis
    József Maléth, Zoltán Rakonczay, Viktória Venglovecz, Nick J. Dolman, Péter Jenő Hegyi · 2012 · Acta Physiologica
  75. Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
    Uğur Eskiocak, Vijayashree Ramesh, Jennifer G. Gill, Zhiyu Zhao, Stacy W. Yuan, Meng Wang, Travis W. Vandergriff, Mark J. Shackleton, Elsa Quintana, Arthur Edward Frankel et al. · 2016 · Nature Communications
  76. The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress
    Hakjoo Lee, Sylvia B. Smith, Shey‐Shing Sheu, Yisang Yoon · 2020 · Journal of Biological Chemistry
  77. “Simple but not simpler”: toward a unified picture of energy requirements in cell death
    Alberto Chiarugi · 2005 · The FASEB Journal
  78. Mitochondrial Transfer as a Therapeutic Strategy Against Ischemic Stroke
    Wei Chen, Jingjing Huang, Hu Y, Seyed Esmaeil Khoshnam, Alireza Sarkaki · 2020 · Translational Stroke Research
  79. Mitochondrial Permeability Transition: A Pore Intertwines Brain Aging and Alzheimer’s Disease
    Kun Jia, Heng Du · 2021 · Cells
  80. Cell Death and Exosomes Regulation After Myocardial Infarction and Ischemia-Reperfusion
    Xun Wu, Chukwuemeka Daniel Iroegbu, Jun Peng, Jianjun Guo, Jinfu Yang, Chengming Fan · 2021 · Frontiers in Cell and Developmental Biology
  81. New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer’s disease
    Sourav Samanta, Firoz Akhter, Anuradha Roy, Doris Chen, Benjamin Turner, Yongfu Wang, Nicolina Clemente, Chunyu Wang, Russell Howard Swerdlow, K.P. Battaile et al. · 2023 · Brain
  82. The role of hexokinase in cardioprotection – mechanism and potential for translation
    Andrew P. Halestrap, Gonçalo C. Pereira, Philippe Pasdois · 2014 · British Journal of Pharmacology
  83. Inhibition of Mitochondrial Membrane Permeability as a Putative Pharmacological Target for Cardioprotection
    Didier Morin, Rana Assaly, Stéphanie Paradis, Alain Berdeaux · 2009 · Current Medicinal Chemistry
  84. The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo
    Hal E. Broxmeyer, Heather A. O’Leary, Xinxin Huang, Charlie Mantel · 2015 · Current Opinion in Hematology
  85. Dysregulated mitochondrial Ca2+ and ROS signaling in skeletal muscle of ALS mouse model
    Jingsong Zhou, Ang Li, Xuejun Li, Jianxun Yi · 2019 · Archives of Biochemistry and Biophysics
  86. What is the nature of the mitochondrial permeability transition pore and What is it Not?
    Detlef Siemen, Mirjam Ziemer · 2013 · IUBMB Life
  87. Dexmedetomidine Ameliorates Hippocampus Injury and Cognitive Dysfunction Induced by Hepatic Ischemia/Reperfusion by Activating SIRT3-Mediated Mitophagy and Inhibiting Activation of the NLRP3 Inflammasome in Young Rats
    Wenli Yu, Jingshu Lyu, Lili Jia, Mingwei Sheng, Hongli Yu, Hongyin Du · 2020 · Oxidative Medicine and Cellular Longevity
  88. Integration of calcium with the signaling network in cardiac myocytes
    MARCUS C. SCHAUB, Martin A. Hefti, Michael Zaugg · 2006 · Journal of Molecular and Cellular Cardiology
  89. Mitochondrial Dysfunction and Permeability Transition in Osteosarcoma Cells Showing the Warburg Effect
    An‐Hoa Giang, Tamara Raymond, Paul S. Brookes, Karen L. de Mesy Bentley, Edward M. Schwarz, Regis J. O’Keefe, Roman A. Eliseev · 2013 · Journal of Biological Chemistry
  90. Chelerythrine Induces Apoptosis through a Bax/Bak-independent Mitochondrial Mechanism
    Kah Fei Wan, Shing Leng Chan, Sunil Kumar Sukumaran, Mei Lee, Victor Chun Kong Yu · 2008 · Journal of Biological Chemistry
  91. Postconditioning by Volatile Anesthetics: Salvaging Ischemic Myocardium at Reperfusion by Activation of Prosurvival Signaling
    Paul S. Pagel · 2008 · Journal of Cardiothoracic and Vascular Anesthesia
  92. MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium
    Baojun Zhang, Si-Qi Liu, Chaoran Li, Erik Allen Lykken, Shan Jiang, Elizabeth Wong, Zhihua Gong, Zhongfen Tao, Bo Zhu, Ying Wan et al. · 2016 · Immunity
  93. The Mitochondrial Permeability Transition Pore and ATP Synthase
    Gisela Beutner, Kambiz N. Alavian, Elizabeth Ann Jonas, George A. Porter · 2016 · Handbook of experimental pharmacology
  94. Deficiency of Mitochondrial Glycerol 3‐Phosphate Dehydrogenase Contributes to Hepatic Steatosis
    Yi Zheng, Hua Qu, Xin Xiong, Yuren Wang, Xiufei Liu, Linlin Zhang, Xiaoyu Liao, Qian Liao, Zheng Sun, Qin Ouyang et al. · 2019 · Hepatology
  95. MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer
    Jae Ho Seo, Young Chan Chae, Andrew V. Kossenkov, Yu Geon Lee, Hsin‐Yao Tang, Ekta Agarwal, Dmitry I. Gabrilovich, Lucia Raffaella Languino, David W. Speicher, Prashanth Krishna Shastrula et al. · 2019 · Cancer Research
  96. Translational issues for mitoprotective agents as adjunct to reperfusion therapy in patients with ST‐segment elevation myocardial infarction
    Hans Erik Bøtker, Héctor A. Cabrera-Fuentes, Marisol Ruiz‐Meana, Gerd Heusch, Michel Ovize · 2020 · Journal of Cellular and Molecular Medicine
  97. Mitochondria and heart failure: new insights into an energetic problem.
    Lei Chen, Anne A. Knowlton · 2010 · PubMed
  98. BH3-only proteins trigger cytochrome c release, but how?
    Georg Alexander Häcker, Arnim Weber · 2007 · Archives of Biochemistry and Biophysics
  99. From bioblasts to mitochondria: ever expanding roles of mitochondria in cell physiology
    Brian P O'Rourke · 2010 · Frontiers in Physiology
  100. Mitochondrial ion channels as targets for cardioprotection
    Derek John Hausenloy, Rainer Schulz, Henrique Girão, Brenda Renata Kwak, Diego De Stefani, Rosario Rizzuto, Paolo Bernardi, Fabio Di Lisa · 2020 · Journal of Cellular and Molecular Medicine