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Biological Approaches to Therapy of Pancreatic Cancer

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It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53

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Inhibition of MDM2 by RG7388 confers hypersensitivity to X-radiation in xenograft models of childhood sarcoma

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Silencing Fibronectin Extra Domain A Enhances Radiosensitivity in Nasopharyngeal Carcinomas Involving an FAK/Akt/JNK Pathway

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Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function

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From tumor prevention to therapy: Empowering p53 to fight back

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Low-dose arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation

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Tyrosine Kinase Inhibitors Protect the Salivary Gland from Radiation Damage by Inhibiting Activation of Protein Kinase C-δ

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p53 status dictates responses of B lymphomas to monotherapy with proteasome inhibitors

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Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis

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Impaired Mitochondrial Metabolism and Mammary Carcinogenesis

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Multiple CT Scans Extend Lifespan by Delaying Cancer Progression in Cancer-Prone Mice

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Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity

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Virtual screening of p53 mutants reveals Y220S as an additional rescue drug target for PhiKan083 with higher binding characteristics

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RNA polymerase III transcription is repressed in response to the tumour suppressor ARF

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Global Effect of Inauhzin on Human p53-Responsive Transcriptome

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A Chemical Modulator of p53 Transactivation that Acts as a Radioprotective Agonist

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LCN2 Is a Potential Biomarker for Radioresistance and Recurrence in Nasopharyngeal Carcinoma

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The Estrogen Receptor Fusion System in Mouse Models: A Reversible SwitchPreprint

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p53 regulates diverse tissue-specific outcomes to endogenous DNA damage in mice

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Loss of function tp53 mutations do not accelerate the onset of myc‐induced T‐cell acute lymphoblastic leukaemia in the zebrafish

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Histone Chaperone Jun Dimerization Protein 2 (JDP2): Role in Cellular Senescence and Aging

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Lysines in the tetramerization domain of p53 selectively modulate G1 arrest

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Tumor Suppression by p53 in the Absence of Atm

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AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation

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Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4–NFκB signalling

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p53 as the main traffic controller of the cell signaling network

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Signaling Pathways in Cancer

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UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity

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An extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancer

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ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2

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Gastric cancer with breast metastasis: Clinical features and prognostic factors

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Pifithrin-α as a Potential Cytoprotective Agent in Radiotherapy: Protection of Normal Tissue without Decreasing Therapeutic Efficacy in Glioma Cells

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Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

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Targeting mutant p53 shows promise for sunscreens and skin cancer

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Elevated Ornithine Decarboxylase Levels Activate Ataxia Telangiectasia Mutated–DNA Damage Signaling in Normal Keratinocytes

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GFI1 Is Repressed by p53 and Inhibits DNA Damage-Induced Apoptosis

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Expression of DNA damage response genes indicate progressive breast tumors

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ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma

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COX‐2 inhibitor NS‐398 suppresses doxorubicin‐induced p53 accumulation through inhibition of ROS‐mediated Jnk activation

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Engaging the p53 metabolic brake drives senescence

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Alterations in the p53 Pathway and p16INK4a Expression Predict Overall Survival in Metastatic Melanoma Patients Treated with Dacarbazine

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Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons

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Can less be more for p53?

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PUMA Kills Stem Cells to Stall Cancer?

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Association of Angiogenesis Markers With Lymph Node Metastasis in Early Colorectal Cancer

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p73 Loss Triggers Conversion to Squamous Cell Carcinoma Reversible upon Reconstitution with TAp73α

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