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Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

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Oxidation as a Post-Translational Modification that Regulates Autophagy

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Regulation of Autophagy by Kinases

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The complex interplay between autophagy and NF-κB signaling pathways in cancer cells.

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The multifaceted regulation and functions of PKM2 in tumor progression

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All-you-can-eat: autophagy in neurodegeneration and neuroprotection

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Protein misfolding and disease: from the test tube to the organism

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Autophagy in the cardiovascular system

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Chaperone-assisted degradation: multiple paths to destruction

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Nutrient-dependent regulation of autophagy through the target of rapamycin pathway

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The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

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Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways

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Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases

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Lysosomal storage diseases as disorders of autophagy

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Atg7 Induces Basal Autophagy and Rescues Autophagic Deficiency in CryAB R120G Cardiomyocytes

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Aggresomes and Pericentriolar Sites of Virus Assembly: Cellular Defense or Viral Design?

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Cellular and Molecular Mechanisms of Prion Disease

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Autophagy genes and ageing

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Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease: Current Evidence and Future Perspectives

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Degradation of tau protein by autophagy and proteasomal pathways

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Autophagy in tumor suppression and cancer therapy

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Autophagy in Protein and Organelle TurnoverPreprint

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The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders

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Small molecule enhancers of autophagy for neurodegenerative diseases

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Free Radicals in Human Health and Disease

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Biophysical and Mechanistic Models for Disease-Causing Protein Variants

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Increased Lysosomal Exocytosis Induced by Lysosomal Ca 2+ Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity

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Membrane Orientation and Subcellular Localization of Transmembrane Protein 106B (TMEM106B), a Major Risk Factor for Frontotemporal Lobar Degeneration

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Heme Oxygenase 1 in the Nervous System: Does It Favor Neuronal Cell Survival or Induce Neurodegeneration?

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Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila

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mTOR's role in ageing: protein synthesis or autophagy?

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Copper: from neurotransmission to neuroproteostasis

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Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms

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BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta

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Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis

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The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides

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UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration

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Small Molecule Enhancers of Rapamycin-Induced TOR Inhibition Promote Autophagy, Reduce Toxicity in Huntington’s Disease Models and Enhance Killing of Mycobacteria by Macrophages

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Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes

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Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux

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The association between Parkinson's disease and melanoma

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Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus

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A Nucleus-based Quality Control Mechanism for Cytosolic Proteins

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Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis

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Parkinson's disease and cancer: two wars, one front

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Recent Advancements of Nanomedicine in Neurodegenerative Disorders Theranostics

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Autophagic control of cell ‘stemness’

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The ubiquitin-proteasome pathway and synaptic plasticityPreprint

Hegde, A. N. (2010) · Learning & Memory · doi:10.1101/lm.1504010 · Cited by 156

REGγ, a proteasome activator and beyond?

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Redox Reactions Induced by Nitrosative Stress Mediate Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

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Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

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Desmin-related cardiomyopathy: an unfolding story

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Neuronal death: where does the end begin?

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Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies

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Proteasome activation by small molecules

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The Amyloid Phenomenon and Its Links with Human DiseasePreprint

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Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens

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Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain

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CSPα knockout causes neurodegeneration by impairing SNAP‐25 function

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Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein

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The cell biology of autophagy in metazoans: a developing story

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Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin–proteasomal and autophagy systems

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Large-Scale Discovery of Non-conventional Peptides in Maize and Arabidopsis through an Integrated Peptidogenomic Pipeline

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Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice

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Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A

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Nanowired Bioelectric Interfaces

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The regulation of aging: does autophagy underlie longevity?

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Pathophysiology of neuropathic lysosomal storage disorders

Bellettato, C. M., & Scarpa, M. (2010) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-010-9075-9 · Cited by 141

Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy

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Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle

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Impaired Protein Aggregate Handling and Clearance Underlie the Pathogenesis of p97/VCP-associated Disease

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Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling

Son, S. M., Jung, E. S., Shin, H. J., Byun, J., & Mook‐Jung, I. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.09.039 · Cited by 142

Oxidized/misfolded superoxide dismutase‐1: the cause of all amyotrophic lateral sclerosis?

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Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders

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Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice

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Astroglial atrophy in Alzheimer’s disease

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HDAC6 a new cellular stress surveillance factor

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Autophagy and misfolded proteins in neurodegeneration

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Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra‐Muscle Fiber Multi‐Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation

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Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity

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Strategies for the Inhibition of Protein Aggregation in Human Diseases

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Characterization of the brain 26S proteasome and its interacting proteins

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The Role of Chaperone-Mediated Autophagy in Huntingtin Degradation

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Accumulation and distribution of α-synuclein and ubiquitin in the CNS of Gaucher disease mouse models

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Autophagy Is Induced by UVA and Promotes Removal of Oxidized Phospholipids and Protein Aggregates in Epidermal Keratinocytes

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