Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

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2. Serotonin-estrogen interactions: What can we learn from pregnancy?
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3. Cytokines, angiogenic, and antiangiogenic factors and bioactive lipids in preeclampsia
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4. Role of corin and atrial natriuretic peptide in preeclampsia
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5. Effect of Prenatal Hypoxia in Transgenic Mouse Models of Preeclampsia and Fetal Growth Restriction
   Christian F. Rueda‐Clausen, Joanna L. Stanley, D. F. Thambiraj, Rajan Poudel, Sandra Thomas Davidge, Philip Newton Baker · 2013 · Reproductive Sciences
6. CDKN1C Mutations in HELLP/Preeclamptic Mothers of Beckwith–Wiedemann Syndrome (BWS) Patients
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7. Comparison of Immune Cell Recruitment and Function in Endometrium During Development of Epitheliochorial (Pig) and Hemochorial (Mouse and Human) Placentas
   Barbara Anne Croy, Jocelyn M. Wessels, Nicola F. Linton, Chandrakant Tayade · 2008 · Placenta
8. Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice
   Megumi Kanasaki, Swayam Prakash Srivastava, Fan Yang, Ling Xu, Sumiyo Kudoh, Munehiro Kitada, Norikazu Ueki, Hyoh Kim, Jinpeng Li, Satoru Takeda et al. · 2017 · Scientific Reports
9. Maternal care boosted by paternal imprinting in mammals
   Hugo Creeth, Gráinne I. McNamara, Simon J. Tunster, Raquel Boqué-Sastre, Bridget Allen, Lorna A. Sumption, Jessica B Eddy, Anthony R Isles, Rosalind M. John · 2018 · PLoS Biology
10. Molecular Mechanisms of Preeclampsia
    N. Vitoratos, Dimitrios Hassiakos, Christos R Iavazzo · 2012 · Journal of Pregnancy
11. Hypothesis: Preeclampsia is a venous disease secondary to an increased intra-abdominal pressure
    Harvey J. Sugerman · 2011 · Medical Hypotheses
12. Estrogen and Preeclampsia: Potential of Estrogens as Therapeutic Agents in Preeclampsia
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13. Inflammation-induced fetal growth restriction in rats is associated with increased placental HIF-1α accumulation
    Kevin P. Robb, Tiziana Cotechini, Camille Allaire, Arissa Sperou, Charles H. Graham · 2017 · PLoS ONE
14. AMP-Activated Protein (AMPK) in Pathophysiology of Pregnancy Complications
    Asako Kumagai, Atsuo Itakura, Daisuke Koya, Keizo Kanasaki · 2018 · International Journal of Molecular Sciences
15. Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice
    Szalai, Gabor, Romero, Roberto, Chaiworapongsa, Tinnakorn, Xu, Yi, Wang, Bing, Ahn, Hyunyoung, Xu, Zhonghui, Chiang, Po Jen, Sundell, Birgitta, Wang, Rona et al. · 2015 · PLoS ONE
16. Estrogen Actions in Placental Vascular Morphogenesis and Spiral Artery Remodeling: A Comparative View between Humans and Mice
    Mariam Rusidzé, Adrien Gargaros, Chanaëlle Fébrissy, Charlotte Dubucs, Ariane Weyl, Jessie Ousselin, Jacqueline Aziza, Jean‐François Arnal, Françoise Lenfant · 2023 · Cells
17. Understanding the Link Between the Placenta and Future Cardiovascular Disease
    Nausheen Siddiqui, Michelle Hladunewich · 2011 · Trends in Cardiovascular Medicine
18. Potential targets for the treatment of preeclampsia
    Charlotte Oyston, Joanna L. Stanley, Philip Newton Baker · 2015 · Expert Opinion on Therapeutic Targets
19. Role of 2-methoxyestradiol, an Endogenous Estrogen Metabolite, in Health and Disease
    Alexis Parada‐Bustamante, Cecilia Valencia, Patricia Reuquén, Patrícia Silva Diaz, Ramiro Javier Rincón‐Rodríguez, Pedro A. Orihuela · 2015 · Mini-Reviews in Medicinal Chemistry
20. Network analysis of the genomic basis of the placebo effect
    Rui‐Sheng Wang, Kathryn Tayo Hall, Franco Giulianini, Dani Passow, Ted Jack Kaptchuk, Joseph Loscalzo · 2017 · JCI Insight
21. The role of genetics in pre-eclampsia and potential pharmacogenomic interventions
    Paula Juliet Williams, Morgan · 2012 · Pharmacogenomics and Personalized Medicine
22. Mice Overexpressing Both Human Angiotensinogen and Human Renin as a Model of Superimposed Preeclampsia on Chronic Hypertension
    Stéphanie Falcao, Ékatherina Stoyanova, Guy Cloutier, Roch Listz Maurice, Jolanta Gutkowska, Julie L. Lavoie · 2009 · Hypertension
23. G protein-coupled receptor 30 regulates trophoblast invasion and its deficiency is associated with preeclampsia
    Chao Tong, Xiang Feng, Jun Chen, Xingchen Qi, Liyuan Zhou, Shuming Shi, Kamana Kc, Joanna L. Stanley, Philip Newton Baker, Hua Zhang · 2016 · Journal of Hypertension
24. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum
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25. The human placenta and its role in reproductive outcomes revisited
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26. Polymorphisms in Catechol- O -Methyltransferase Modify Treatment Effects of Aspirin on Risk of Cardiovascular Disease
    Kathryn Tayo Hall, Christopher P. Nelson, Roger B. Davis, Julie E. Buring, Irving Kirsch, Murray A. Mittleman, Joseph Loscalzo, Nilesh J. Samani, Paul M. Ridker, Ted Jack Kaptchuk et al. · 2014 · Arteriosclerosis Thrombosis and Vascular Biology
27. Redox-Sensitive Transcription Factor NRF2 Enhances Trophoblast Differentiation via Induction of miR-1246 and Aromatase
    Sribalasubashini Muralimanoharan, Youn-Tae Kwak, Carole R. Mendelson · 2018 · Endocrinology
28. Circulating and Vascular Bioactive Factors During Hypertension in Pregnancy
    Alain F. Tanbe, Raouf A. Khalil · 2010 · Current Bioactive Compounds
29. Estradiol-17β and its Cytochrome P450- and Catechol-O-Methyltransferase–Derived Metabolites Selectively Stimulate Production of Prostacyclin in Uterine Artery Endothelial Cells
    Sheikh O. Jobe, Jayanth Ramadoss, Andrew J. Wargin, Ronald R. Magness · 2013 · Hypertension
30. Angiogenesis factors and preeclampsia
    Ralf Dechend, Friedrich Cameron Luft · 2008 · Nature Medicine
31. Decreased Maternal Serum 2-Methoxyestradiol Levels are Associated with the Development of Preeclampsia
    Zhijun Shen, Yanming Wu, Xiao Chen, Xinwen Chang, Qian Zhou, Jian Zhou, Hao Ying, Jing Juan Zheng, Tao Duan, Kai Wang · 2014 · Cellular Physiology and Biochemistry
32. Endothelial growth factor therapy improves preeclampsia-like manifestations in a murine model induced by overexpression of sVEGFR-1
    Julio Mateus, Egle Bytautiene, Fangxian Lu, Esther H. Tamayo, Ancizar Betancourt, Gary D.V. Hankins, Monica Longo, George Robert Saade · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
33. Estrogen metabolism pathways in preeclampsia and normal pregnancy
    David E. Cantonwine, Thomas Frederick McElrath, Britton L. Trabert, Xia Xu, Joshua Neil Sampson, James Michael Roberts, Robert N. Hoover, Rebecca J. Troisi · 2019 · Steroids
34. Hypoxia-induced Downregulation of SRC-3 Suppresses Trophoblastic Invasion and Migration Through Inhibition of the AKT/mTOR Pathway: Implications for the Pathogenesis of Preeclampsia
    Chengjin He, Nan Shan, Ping A. Xu, Huisheng Ge, Yu Jing Yuan, Yangming Liu, Pu Zhang, Li Wen, Fumei Zhang, Liling Xiong et al. · 2019 · Scientific Reports
35. Placental HtrA3 Is Regulated by Oxygen Tension and Serum Levels Are Altered during Early Pregnancy in Women Destined to Develop Preeclampsia
    Ying Li, Michelle A. Puryer, E. Lin, Kathryn Hale, Lois A. Salamonsen, Ursula Manuelpillai, Stephen Y. C. Tong, Weng Chan, Euan Morrison Wallace, Guiying Nie · 2010 · The Journal of Clinical Endocrinology & Metabolism
36. Current State of Preeclampsia Mouse Models: Approaches, Relevance, and Standardization
    Christopher A. Waker, Melissa R. Kaufman, Thomas L. Brown · 2021 · Frontiers in Physiology
37. Metabolic Pathways Involved in 2-Methoxyestradiol Synthesis and Their Role in Preeclampsia
    Alejandra Pérez‐Sepúlveda, Pedro P. España-Perrot, Errol R. Norwitz, Sebastian Enrique Illanes · 2013 · Reproductive Sciences
38. Molecular determinants of microvascular dysfunction in hypertensive pregnancy and preeclampsia
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39. Safety Evaluation of Tadalafil Treatment for Fetuses with Early-Onset Growth Restriction (TADAFER): Results from the Phase II Trial
    Shintaro Maki, Hiroaki Tanaka, Makoto Tsuji, Fumi H. Furuhashi, Shoichi Magawa, Michiko K. Kaneda, Masafumi Nii, Kayo Tanaka, Eiji Kondo, Satoshi Tamaru et al. · 2019 · Journal of Clinical Medicine
40. Hypoxia and the integrated stress response promote pulmonary hypertension and preeclampsia: Implications in drug development
    Xiang‐Qun Hu, Li Zhang · 2021 · Drug Discovery Today
41. Putting pressure on pre-eclampsia
    Samir M. Parikh, S. Ananth Karumanchi · 2008 · Nature Medicine
42. Quantification of Gestational Changes in the Uteroplacental Vascular Tree Reveals Vessel Specific Hemodynamic Roles During Pregnancy in Mice
    Monique Y. Rennie, Kathie J. Whiteley, S. Lee Adamson, John G. Sled · 2016 · Biology of Reproduction
43. The Synthesis and Metabolism of Steroid Hormones
    Jerome F. Strauss · 2009 · Elsevier eBooks
44. Association of oxidative stress-related genes with idiopathic recurrent miscarriage
    Maryam B. Khadzhieva, N. N. Lutcenko, Ilya V. Volodin, K. V. Morozova, Lyubov E. Salnikova · 2014 · Free Radical Research
45. Effect of Oxidative Stress on the Estrogen-NOS-NO-KCa Channel Pathway in Uteroplacental Dysfunction: Its Implication in Pregnancy Complications
    Xiang‐Qun Hu, Rui Song, Li Zhang · 2019 · Oxidative Medicine and Cellular Longevity
46. Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay
    April M. Bobenchik, Jae‐Yeon Choi, Arunima Mishra, Iulian N. Rujan, Bing Hao, Dennis R. Voelker, Jeffrey C. Hoch, Choukri Ben Mamoun · 2010 · BMC Biochemistry
47. Levels of Key Enzymes of Methionine-Homocysteine Metabolism in Preeclampsia
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48. Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17 in preeclampsia
    Ji Hyae Lim, Shin Young Kim, Do-Jin Kim, So Yeon Park, Ho Won Han, Jung Yeol Han, Si Won Lee, Jae Hyug Yang, Hyun Mee Ryu · 2010 · Pharmacogenetics and Genomics
49. Role of 2-methoxyestradiol as inhibitor of arthritis and osteoporosis in a model of postmenopausal rheumatoid arthritis
    Alexandra Stubelius, Emil Andréasson, Anna Karlsson, Claes Ohlsson, Åsa Tivesten, Ulrika Islander, Hans Carlsten · 2011 · Clinical Immunology
50. New insight into the role of long non-coding RNAs in the pathogenesis of preeclampsia
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51. Severe Early-Onset Preeclampsia Is Not Associated with a Change in Placental Catechol O-Methyltransferase (COMT) Expression
    Kirsten Rebecca Palmer, Burcu Sağlam, Clare L. Whitehead, Owen Stock, Martha Lappas, Stephen Y. C. Tong · 2011 · American Journal Of Pathology
52. Plasma level of hydroxysteroid (17-β) dehydrogenase 1 in the second trimester is an independent risk factor for predicting preeclampsia after adjusting for the effects of mean blood pressure, bilateral notching and plasma level of soluble fms-like tyrosine kinase 1/placental growth factor ratio
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53. Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin II
    Norikazu Ueki, Keizo Kanasaki, Megumi Kanasaki, Satoru Takeda, Daisuke Koya · 2017 · Hypertension
54. Establishing life is a calcium-dependent TRiP: Transient receptor potential channels in reproduction
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55. Low 2‐methoxyestradiol levels at the first trimester of pregnancy are associated with the development of pre‐eclampsia
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56. Inhibition of rat aortic smooth muscle contraction by 2-methoxyestradiol
    Yu Gui, Xi‐Long Zheng, Jie Zheng, Michael P. Walsh · 2008 · American Journal of Physiology-Heart and Circulatory Physiology
57. Placental Vasculogenesis Is Regulated by Keratin-Mediated Hyperoxia in Murine Decidual Tissues
    Cornelia Kröger, Preethi Vijayaraj, Ursula Reuter, Reinhard Windoffer, David G. Simmons, Lukas Carl Heukamp, Rudolf E. Leube, Thomas Michael Magin · 2011 · American Journal Of Pathology
58. Green Tea Extract Inhibition of Human Leiomyoma Cell Proliferation Is Mediated via Catechol-O-Methyltransferase
    Dong Zhang, Veera S. Rajaratnam, Omar Al-Hendy, Sunil K. Halder, Ayman A. Al-Hendy · 2014 · Gynecologic and Obstetric Investigation
59. Pregnancy-associated homeostasis and dysregulation: lessons from genetically modified animal models
    Junji Ishida, T. Matsuoka, Tomoko Saito‐Fujita, S. Inaba, Satoshi Kunita, Fumihiro Sugiyama, Ken-ichi YAGAMI, Akiyoshi Fukamizu · 2011 · The Journal of Biochemistry
60. Current model systems for the study of preeclampsia
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61. Higher Estrogen Levels During Pregnancy in Andean Than European Residents of High Altitude Suggest Differences in Aromatase Activity
    Charles, Shelton M., Julian, Colleen G., Vargas, Enrique, Moore, Lorna G. · 2014 · The Journal of Clinical Endocrinology & Metabolism
62. MicroRNAs: key regulators of the trophoblast function in pregnancy disorders
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63. The Placenta in Normal Pregnancy and Preeclampsia
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64. Development of GC–MS/MS method with programmable temperature vaporization large volume injection for monitoring of 17β-estradiol and 2-methoxyestradiol in plasma
    Andreas K. Tsakalof, Dimitrios C. Gkagtzis, GEORGE N. KOUKOULIS, Christos S. Hadjichristodoulou · 2011 · Analytica Chimica Acta
65. Association Between Val158Met Functional Polymorphism in the COMT Gene and Risk of Preeclampsia in a Chinese Population
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66. Alleviation of preeclampsia-like symptoms through PlGF and eNOS regulation by hypoxia- and NF-κB-responsive miR-214-3p deletion
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68. Dopamine in the Pathophysiology of Preeclampsia and Gestational Hypertension: Monoamine Oxidase (MAO) and Catechol-O-methyl Transferase (COMT) as Possible Mechanisms
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69. Obstructive sleep apnea, gestational hypertension and preeclampsia
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70. Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome
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71. Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase
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72. The Relevance of the Renin-Angiotensin System in the Development of Drugs to Combat Preeclampsia
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73. 2-Methoxyestradiol Plasma Levels Are Associated With Clinical Severity Indices and Biomarkers of Preeclampsia
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74. The placental programming hypothesis: Placental endocrine insufficiency and the co-occurrence of low birth weight and maternal mood disorders
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75. The impact of micronutrient deficiency on pregnancy complications and development origin of health and disease
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76. HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2
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77. Evaluation of MutS and Mut+ Pichia pastoris Strains for Membrane-Bound Catechol-O-Methyltransferase Biosynthesis
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78. Mechanisms of Uterine Artery Dysfunction in Pregnancy Complications
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79. Systems Pharmacogenomics – Gene, Disease, Drug and Placebo Interactions: A Case Study in COMT
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80. Melatonin in Health and Disease: A Perspective for Livestock Production
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81. Mouse models for preeclampsia: disruption of redox-regulated signaling
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82. Change of Genes in Calcium Transport Channels Caused by Hypoxic Stress in the Placenta, Duodenum, and Kidney of Pregnant Rats1
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83. PHYSIOLOGY AND ENDOCRINOLOGY SYMPOSIUM: Alterations in uteroplacental hemodynamics during melatonin supplementation in sheep and cattle1
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85. Bone-marrow-derived endothelial progenitor cells contribute to vasculogenesis of pregnant mouse uterus†
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86. 2-Methoxyestradiol Induces Vasodilation by Stimulating NO Release via PPARγ/PI3K/Akt Pathway
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87. DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol
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