Kalluri, Raghu

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin‐Smith, G. K., et al. (2018) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 11,099

The biology , function , and biomedical applications of exosomes

Kalluri, R., & LeBleu, V. S. (2020) · Science

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 10,770

The basics of epithelial-mesenchymal transition

Kalluri, R., & Weinberg, R. A. (2009) · Journal of Clinical Investigation

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 10,196

Fibroblasts in cancer

Kalluri, R., & Zeisberg, M. (2006) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 4,538

The biology and function of fibroblasts in cancer

Kalluri, R. (2016) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 4,366

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., LeBleu, V. S., Mittendorf, E. A., Weitz, J., Rahbari, N., et al. (2015) · Nature

Extracellular vesicles in diseaseCancer Genomics and Diagnostics

Cited by 2,880

B cells and tertiary lymphoid structures promote immunotherapy response

Helmink, B. A., Reddy, S. M., Gao, J., Zhang, S., Basar, R., Thakur, R., Yizhak, K., Sade-Feldman, M., Blando, J., Han, G., et al. (2020) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 2,731

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

Özdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C.-C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V., et al. (2014) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 2,681

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Kamerkar, S., LeBleu, V. S., Sugimoto, H., Yang, S., Ruivo, C. F., Melo, S. A., Lee, J. J., & Kalluri, R. (2017) · Nature

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 2,639

Guidelines and definitions for research on epithelial-mesenchymal transition

Yang, J., Antin, P., Berx, G., Blanpain, C., Brabletz, T., Bronner, M., Campbell, K., Cano, A., Casanova, J., Christofori, G., et al. (2020) · Nature Reviews Molecular Cell Biology

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 2,226

EMT in cancer

Brabletz, T., Kalluri, R., Nieto, M. A., & Weinberg, R. A. (2018) · Nature Reviews Cancer

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 1,961

Clinical and therapeutic relevance of cancer-associated fibroblasts

Chen, Y., McAndrews, K. M., & Kalluri, R. (2021) · Nature Reviews Clinical Oncology

Cancer Cells and MetastasisPancreatic and Hepatic Oncology Research

Cited by 1,230

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

Zeisberg, E. M., Potenta, S., Xie, L., Zeisberg, M., & Kalluri, R. (2007) · Cancer Research

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 1,011

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

Carstens, J. L., Correa de Sampaio, P., Yang, D., Barua, S., Wang, H., Rao, A., Allison, J. P., LeBleu, V. S., & Kalluri, R. (2017) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 633

The origin of fibroblasts and mechanism of cardiac fibrosis

Krenning, G., Zeisberg, E. M., & Kalluri, R. (2010) · Journal of Cellular Physiology

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 601

Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

Chen, Y., Kim, J., Yang, S., Wang, H., Wu, C.-J., Sugimoto, H., LeBleu, V. S., & Kalluri, R. (2021) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 566

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

Melo, C. A., Drost, J., Wijchers, P. J., van de Werken, H., de Wit, E., Vrielink, J. A. F. O., Elkon, R., Melo, S. A., Léveillé, N., Kalluri, R., et al. (2013) · Molecular Cell

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 544

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

Cooke, V. G., LeBleu, V. S., Keskin, D., Khan, Z., O'Connell, J. T., Teng, Y., Duncan, M. B., Xie, L., Maeda, G., Vong, S., et al. (2012) · Cancer Cell

Angiogenesis and VEGF in CancerCancer Cells and Metastasis

Cited by 530

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

Affo, S., Nair, A., Brundu, F., Ravichandra, A., Bhattacharjee, S., Matsuda, M., Chin, L., Filliol, A., Wen, W., Song, X., et al. (2021) · Cancer Cell

Cholangiocarcinoma and Gallbladder Cancer StudiesLiver physiology and pathology

Cited by 416

Mechanisms associated with biogenesis of exosomes in cancer

McAndrews, K. M., & Kalluri, R. (2019) · Molecular Cancer

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 394

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

Kanasaki, K., Palmsten, K., Sugimoto, H., Ahmad, S., Hamano, Y., Xie, L., Parry, S., Augustin, H. G., Gattone, V. H., Folkman, J., et al. (2008) · Nature

Pregnancy and preeclampsia studiesNeurological Complications and Syndromes

Cited by 381

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Bhattacharjee, S., Hamberger, F., Ravichandra, A., Miller, M., Nair, A., Affo, S., Filliol, A., Chin, L., Savage, T. M., Yin, D., et al. (2021) · Journal of Clinical Investigation

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 367

VEGF-A and Tenascin-C produced by S100A4 + stromal cells are important for metastatic colonization

O'Connell, J. T., Sugimoto, H., Cooke, V. G., MacDonald, B. A., Mehta, A. I., LeBleu, V. S., Dewar, R., Rocha, R. M., Brentani, R. R., Resnick, M. B., et al. (2011) · Proceedings of the National Academy of Sciences

S100 Proteins and AnnexinsCancer Cells and Metastasis

Cited by 348

Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

Chen, Y., Yang, S., Tavormina, J., Tampe, D., Zeisberg, M., Wang, H., Mahadevan, K. K., Wu, C.-J., Sugimoto, H., Chang, C.-C., et al. (2022) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 289