The role of exercise and PGC1α in inflammation and chronic disease

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

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Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

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Exercise builds brain health: key roles of growth factor cascades and inflammation

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Transcriptome Analysis Reveals That Alfalfa Promotes Rumen Development Through Enhanced Metabolic Processes and Calcium Transduction in Hu Lambs

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Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1 α and irisin in a rat model of type 2 diabetes mellitus

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Low-intensity exercise in the acute phase of lipopolysaccharide-induced sepsis improves lipid metabolism and survival in mice by stimulating PGC-1α expression

Irahara, T., Sato, N., Inoue, K., Otake, K., Ohtsuru, S., Koike, K., Fushiki, T., & Yokota, H. (2016) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000001023 · Cited by 18

Overall and abdominal obesity and risks of all-cause and cause-specific mortality in Korean adults: a pooled analysis of three population-based prospective cohorts

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Secreted Protein Acidic and Rich in Cysteine (SPARC)—Mediated Exercise Effects: Illustrative Molecular Pathways against Various Diseases

Ghanemi, A., Yoshioka, M., & St‐Amand, J. (2023) · Diseases · doi:10.3390/diseases11010033 · Cited by 17

Editor's Choice -- Exercise Therapy for Chronic Symptomatic Peripheral Artery Disease: A Clinical Consensus Document of the European Society of Cardiology Working Group on Aorta and Peripheral Vascular Diseases in Collaboration With the European Society of Vascular Medicine and the European Society for Vascular Surgery

Mazzolai, L., Belch, J. J. F., Venermo, M. A., Aboyans, V., Brodmann, M., Bura-Rivière, A., Debus, S., Espinola–Klein, C., Harwood, A. E., Hawley, J. A., et al. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.01.009 · Cited by 17

Wheat seedlings extract ameliorates sarcopenia in aged mice by regulating protein synthesis and degradation with anti-inflammatory and mitochondrial biogenesis effects

Han, J.-W., Shin, S., Bae, H. R., Lee, H., Moon, S. Y., Seo, W. D., & Kwon, E. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.155747 · Cited by 17

Increased 24-hour ad libitum food intake is associated with lower plasma irisin concentrations the following morning in adult humans

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Evolving therapies for non-alcoholic steatohepatitis

Tilg, H., & Moschen, A. R. (2014) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2014.911283 · Cited by 18

Altered irisin/BDNF axis parallels excessive daytime sleepiness in obstructive sleep apnea patients

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Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs

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Anti-inflammatory effects of exercise training. A systematic review

Onu, I., Iordan, D. A., Codreanu, C. M., Daniela, M., & Galaction, A. (2021) · Balneo and PRM Research Journal · doi:10.12680/balneo.2021.473 · Cited by 17

Does the Microbiota Composition Influence the Efficacy of Colorectal Cancer Immunotherapy?

Lin, Y., Kong, D.-X., & Zhang, Y.-N. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.852194 · Cited by 17

Altered muscle oxidative phenotype impairs exercise tolerance but does not improve after exercise training in multiple sclerosis

Spaas, J., Goulding, R. P., Keytsman, C., Fonteyn, L., van Horssen, J., Jaspers, R. T., Eijnde, B. O., & Wüst, R. C. I. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13050 · Cited by 17

Effect of exercise on concentrations of irisin in overweight individuals: A systematic review

Andrade, P. A., Silveira, B. K. S., Rodrigues, A. C., da Silva, F. M. O., Rosa, C. O. B., & Alfenas, R. D. C. G. (2018) · Science & Sports · doi:10.1016/j.scispo.2017.11.002 · Cited by 17

Association of Circulating Irisin Concentrations with Weight Loss after Roux-en-Y Gastric Bypass Surgery

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BPCO et inflammation: mise au point d’un groupe d’experts. Les mécanismes de l’inflammation et du remodelage

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Predicting healthspan and disease risks through biological age

Li, G., Cheng, L., Wong, I. N., Yin, Y., Chen, J., Liu, L., & Zhang, K. (2025) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2025.10.006 · Cited by 16

Revisiting Skeletal Muscle Dysfunction and Exercise in Chronic Obstructive Pulmonary Disease: Emerging Significance of Myokines

Han, L., Li, P., He, Q., Yang, C. G., Jiang, M., Wang, Y., Cao, Y., Han, X., Liu, X., & Wu, W. (2023) · Aging and Disease · doi:10.14336/ad.2023.1125 · Cited by 17

Parkinson disease-induced upregulation of apoptotic mediators could be attenuated in the skeletal muscle following chronic exercise training

Al-Jarrah, M. D., & Erekat, N. S. (2017) · Neurorehabilitation · doi:10.3233/nre-172196 · Cited by 16

Pathophysiological significance of hepatokine overproduction in type 2 diabetes

Misu, H. (2018) · Diabetology International · doi:10.1007/s13340-018-0368-9 · Cited by 16

Functional genomics applications and therapeutic implications in sarcopenia

Melouane, A., Ghanemi, A., Yoshioka, M., & St‐Amand, J. (2019) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2019.04.003 · Cited by 16

Vascular endothelial growth factor B inhibits lipid accumulation in C2C12 myotubes incubated with fatty acids

Li, L.-J., Ma, J., Li, S., Chen, X., & Zhang, J. (2019) · Growth Factors · doi:10.1080/08977194.2019.1626851 · Cited by 16

Aerobic exercise and lipolysis: A review of the β-adrenergic signaling pathways in adipose tissue

Rodrigues, A. C., Prímola‐Gomes, T. N., Pelúzio, M. D. C. G., Hermsdorff, H. H. M., & Natali, A. J. (2020) · Science & Sports · doi:10.1016/j.scispo.2020.04.006 · Cited by 16

Sex‐based differences after a single bout of exercise on PGC1α isoforms in skeletal muscle: A pilot study

Damico, D. C. S., Marino, A., Macaluso, F., Paladino, L., Scalia, F., Spinoso, G., Dimauro, I., Caporossi, D., Cappello, F., Felice, V. D., et al. (2021) · The FASEB Journal · doi:10.1096/fj.202002173r · Cited by 17

Antioxidants and Exercise: A Redox-Informed Framework for Training Adaptation, Performance, and Recovery

Mănescu, D. C., Tudor, A. C., Mănescu, A. M., Mărgărit, I. R., Mănescu, C. O., Prisăcaru, C., Păun, L., & Tudor, V. (2026) · Antioxidants · doi:10.3390/antiox15040456 · Cited by 15

The regulating pathway of creatine on muscular protein metabolism depends on the energy state

Sun, M., Jiao, H., Wang, X., Li, H., Zhou, Y., Zhao, J., & Lin, H. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00447.2021 · Cited by 17

Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism

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Aging‐associated decrease of PGC ‐1α promotes pain chronification

Wu, X., Yang, L., Li, Z., Gu, C., Jin, K., Luo, A., Rasheed, N. F., Fiutak, I., Chao, K., Chen, A., et al. (2024) · Aging Cell · doi:10.1111/acel.14177 · Cited by 15

Relationship among muscle strength, muscle endurance, and skeletal muscle oxygenation dynamics during ramp incremental cycle exercise

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Linoleic Acid Promotes Mitochondrial Biogenesis and Alleviates Acute Lung Injury

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Inspiratory training increases insulin sensitivity in elderly patients

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Treating the Systemic Effects of Chronic Obstructive Pulmonary Disease

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Acute Effect of Different Patterns of Exercise on Mood, Anxiety and Cortical Activity

Guimarães, T. T., da Costa, B. M., Cerqueira, L. S., Serdeiro, A. D. C. A., Pompeu, F. A. M. S., Moraes, H., Santos, T. M., & Deslandes, A. C. (2014) · Archives of Neuroscience · doi:10.5812/archneurosci.18781 · Cited by 15

Role of Biomarkers in Medicine

Wang, M., & Witzmann, F. A. (2016) · InTech eBooks · doi:10.5772/61449 · Cited by 16

Blind Spot for Sedentarism: Redefining the Diseasome of Physical Inactivity in View of Circadian System and the Irisin/BDNF Axis

Zsuga, J., Móré, C. E., Erdei, T., Papp, C., Harsányi, S., & Gesztelyi, R. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00818 · Cited by 16

Salvianolic acid B ameliorates liver injury in a murine aGvHD model by decreasing inflammatory responses via upregulation of HO-1

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Randomized Trial: D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans

Hirvonen, O. P., Kyröläinen, H., Lehti, M., & Kainulainen, H. (2021) · Frontiers in Aging · doi:10.3389/fragi.2021.752636 · Cited by 15

Prospective Real-World Analysis of Asthma Patients With Preserved and Reduced Physical Activity

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Implications of Pericardial, Visceral and Subcutaneous Adipose Tissue on Vascular Inflammation Measured Using 18FDG-PET/CT

Hong, H. C., Hwang, S. Y., Park, S., Ryu, J. Y., Choi, H. Y., Yoo, H. J., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135294 · Cited by 15

Modulation of Cardiovascular Toxicity in Hodgkin Lymphoma: Potential Role and Mechanisms of Aerobic Training

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Associations with Physical Activity, Chronic Disease, Depression, and Health-Related Quality of Life

Park, S. Y. (2014) · Korean Journal of Sport Science · doi:10.24985/kjss.2014.25.2.249 · Cited by 15

Understanding mitochondrial biogenesis through energy sensing pathways and its translation in cardio-metabolic health

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Reducción del riesgo cardiovascular en mujeres adultas mediante ejercicio físico de sobrecarga

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Skeletal muscle innervation: Reactive oxygen species as regulators of neuromuscular junction dynamics and motor unit remodeling

Guzman, S. D., & Brooks, S. V. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.01.053 · Cited by 14

The combination of oral quercetin supplementation and exercise prevents brain mitochondrial biogenesis

Casuso, R. A., López, E. J. M., Hita‐Contreras, F., Camiletti‐Moirón, D., Martínez‐Romero, R., Cañuelo, A., & Martínez‐Amat, A. (2014) · Genes & Nutrition · doi:10.1007/s12263-014-0420-8 · Cited by 14

Molecular dynamics simulation and steered molecular dynamics simulation on irisin dimers

Gao, Q., Lu, C., Wang, X., Zhang, J., Song, Y., & Xue, Y. Y. (2018) · Journal of Molecular Modeling · doi:10.1007/s00894-018-3609-8 · Cited by 14

Skeletal muscle: not simply an organ for locomotion and energy storage

Lancaster, G. I., & Febbraio, M. A. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.165753 · Cited by 14

Expression of Adenine Nucleotide Translocase (ANT) Isoform Genes Is Controlled by PGC‐1α Through Different Transcription Factors

Gavaldà‐Navarro, A., Villena, J. A., Planavila, A., Viñas, O., & Mampel, T. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24671 · Cited by 14

Pathological and Behavioral Risk Factors for Higher Serum C-Reactive Protein Concentrations in Free-Living Adults—a Brazilian Community-Based Study

Moreto, F., de Oliveira, E. P., Manda, R. M., Torezan, G. A., Teixeira, O., Michelin, E., & Burini, R. C. (2012) · Inflammation · doi:10.1007/s10753-012-9515-9 · Cited by 14

Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation

Song, Z., Cooper, D. K. C., Cai, Z., & Mou, L. (2018) · BioMed Research International · doi:10.1155/2018/2983908 · Cited by 14

SnapShot: NR Coregulators

McKenna, N. J., & O’Malley, B. W. (2010) · Cell · doi:10.1016/j.cell.2010.09.032 · Cited by 14

Distinct Roles of Zmynd17 and PGC1α in Mitochondrial Quality Control and Biogenesis in Skeletal Muscle

Yoshioka, K., Fujita, R., Seko, D., Suematsu, T., Miura, S., & Ono, Y. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00330 · Cited by 14

Small peptides: Could they have a big role in metabolism and the response to exercise?

Atakan, M. M., Türkel, İ., Özerkliğ, B., Koşar, Ş. N., Taylor, D. F., Yan, X., & Bishop, D. J. (2024) · The Journal of Physiology · doi:10.1113/jp283214 · Cited by 13

Targeting Sarcopenia in CKD: The Emerging Role of GLP-1 Receptor Agonists

Llinares-Arvelo, V., Martínez‐Alberto, C. E., González-Luis, A., Macía-Heras, M., Siverio-Morales, O., Navarro‐González, J. F., & Donate‐Correa, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26168096 · Cited by 14

Impact of exercise on immune cell infiltration in muscle tissue: implications for muscle repair and chronic disease

Su, Y., & Su, Z. (2025) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01852-3 · Cited by 13

Chronic voluntary wheel running exercise ameliorates metabolic dysfunction via PGC-1α expression independently of FNDC5/irisin pathway in high fat diet-induced obese mice

Cho, C., Ji, M., Cho, E., Yi, S., Kim, J. G., & Lee, S. (2023) · The Journal of Physiological Sciences · doi:10.1186/s12576-023-00864-6 · Cited by 14

The Function and Mechanism of Anti-Inflammatory Factor Metrnl Prevents the Progression of Inflammatory-Mediated Pathological Bone Osteolytic Diseases

Liu, N., Dong, J., Li, L., Zhou, D., & Liu, F. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s455790 · Cited by 13

Effects triggered in the periphery by acupuncture

Lund, I., & Lundeberg, T. (2015) · Acupuncture and Related Therapies · doi:10.1016/j.arthe.2015.08.002 · Cited by 13

Common traits between the beige fat-inducing stimuli

Stojanović, O., Kieser, S., & Trajkovski, M. (2018) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2018.05.011 · Cited by 13

BST204, a Rg3 and Rh2 Enriched Ginseng Extract, Upregulates Myotube Formation and Mitochondrial Function in TNF-α-Induced Atrophic Myotubes

Lee, S.-J., Im, M., Park, S. K., Kim, J. Y., So, E. Y., Liang, O. D., Kang, J., & Bae, G. (2020) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x20500329 · Cited by 13

Exercise therapy for chronic symptomatic peripheral artery disease

Mazzolai, L., Belch, J. J. F., Venermo, M. A., Aboyans, V., Brodmann, M., Bura-Rivière, A., Debus, S., Espinola–Klein, C., Harwood, A. E., Hawley, J. A., et al. (2024) · VASA · doi:10.1024/0301-1526/a001112 · Cited by 13

Changes in malondialdehyde and C-reactive protein concentrations after lifestyle modification are related to different metabolic syndrome-associated pathophysiological processes

Moreto, F., Kano, H. T., Torezan, G. A., de Oliveira, E. P., Manda, R. M., Teixeira, O., Michelin, E., Corrêa, C. R., & Burini, R. C. (2015) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2015.04.008 · Cited by 13

Association of Irisin Circulating Level with Diabetic Retinopathy: A Case-Control Study

Tarboush, N. A., Yaghi, N. E. A., Ejeilat, L. H. A., Wahed, R. K. A., & Jeris, I. N. (2018) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-0723-3749 · Cited by 13

Decreased PGC-1α Post-Cardiopulmonary Bypass Leads to Impaired Oxidative Stress in Diabetic Patients

Mahmood, E., Jeganathan, J., Feng, R., Saraf, M., Khabbaz, K. R., Mahmood, F., Senthilnathan, V., Liu, D., Chu, L. M., Parikh, S. M., et al. (2018) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2018.08.009 · Cited by 13

Mechanisms Through Which Some Mitochondria-Generated Metabolites Act as Second Messengers That Are Essential Contributors to the Aging Process in Eukaryotes Across Phyla

Dakik, P., Medkour, Y., Mohammad, K., & Titorenko, V. I. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00461 · Cited by 13

Physical Exercise Exacerbates Acute Kidney Injury Induced by LPS via Toll-Like Receptor 4

Húngaro, T. G. R., Freitas‐Lima, L. C., Gregnani, M. F., Perilhão, M. S., Alves-Silva, T., Arruda, A. C., Barrera‐Chimal, J., Estrela, G. R., & Araújo, R. C. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00768 · Cited by 13

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases

Svensson, K., & Handschin, C. (2014) · Drug Discovery Today · doi:10.1016/j.drudis.2014.02.013 · Cited by 13

Tryptophan-Kynurenine Metabolites in Exercise and Mental Health

Valente‐Silva, P., & Ruas, J. L. (2017) · Research and perspectives in endocrine interactions · doi:10.1007/978-3-319-72790-5_7 · Cited by 13

Late-onset megaconial myopathy in mice lacking group I Paks

Joseph, G. A., Hung, M., Goel, A. J., Hong, M., Rieder, M.-K., Beckmann, N. D., Serasinghe, M. N., Chipuk, J. E., Devarakonda, P. M., Goldhamer, D. J., et al. (2019) · Skeletal Muscle · doi:10.1186/s13395-019-0191-4 · Cited by 13

Objectively assessed physical activity, adiposity, and inflammatory markers in people with type 2 diabetes

Hamer, M., Hackett, R. A., Bostock, S., Lazzarino, A. I., Carvalho, L. A., & Steptoe, A. (2014) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2014-000030 · Cited by 12

Prevalence and risk factors of musculoskeletal pain in patients with chronic obstructive pulmonary disease: A systematic review

Latiers, F., Vandenabeele, M., Poncin, W., & Reychler, G. (2021) · The Clinical Respiratory Journal · doi:10.1111/crj.13443 · Cited by 12

Stress and Kynurenine-Inflammation Pathway in Major Depressive Disorder

Mingoti, M. E. D., Bertollo, A. G., de Oliveira, T., & Ignácio, Z. M. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-7376-5_8 · Cited by 12

Decoding the Gut-Brain Axis: A Journey toward Targeted Interventions for Disorders-of-Gut-Brain Interaction

Holtmann, G., Moniruzzaman, M., & Shah, A. (2025) · Digestive Diseases · doi:10.1159/000543845 · Cited by 12

Consecutive skeletal muscle PGC-1α overexpression: A double-edged sword for mitochondrial health in the aging brain

Zhou, L., Mozaffaritabar, S., Koltai, E., Giannopoulou, S., Kolonics, A., Gu, Y., Pinho, R. A., Miklóssy, I., Boldogh, I. R., & Radak, Z. O. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167851 · Cited by 12

Are There Limitations to Exercise Benefits in Peripheral Arterial Disease?

Zakari, M. O., Alsahly, M. B., Koch, L. G., Britton, S. L., Katwa, L. C., & Lust, R. M. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00173 · Cited by 12

Effect of 3-week preoperative rehabilitation on pain and daily physical activities in patients with severe osteoarthritis undergoing total knee arthroplasty

Ohno, C., Ogawa, T., Taniguchi, T., Kinoshita, T., Fujita, Y., Nishimura, Y., Yamada, H., & Tajima, F. (2022) · British Journal of Pain · doi:10.1177/20494637221084190 · Cited by 12

Effects of Low-Intensity and Long-Term Aerobic Exercise on the Psoas Muscle of mdx Mice: An Experimental Model of Duchenne Muscular Dystrophy

Sigoli, E., Antão, R. A., Guerreiro, M. P., de Araújo, T. O. P., dos Santos, P. K., da Roza, D. L., Rassier, D. E., & Cornachione, A. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094483 · Cited by 13

Mitochondrial dynamics: roles in exercise physiology and muscle mass regulation

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Correlation between frailty and reduction in cortical thickness in patients with chronic obstructive pulmonary disease

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An essential role for E wing sarcoma gene ( EWS ) in early white adipogenesis

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In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice†

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Transcriptional modulation of mitochondria biogenesis pathway at and above critical speed in mice

Mille-Hamard, L., Breuneval, C., Rousseau, A., Grimaldi, P. A., & Billat, V. L. (2015) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-015-2413-3 · Cited by 13

Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation

Haralampieva, D., Salemi, S., Dinulović, I., Sulser, T., Ametamey, S. M., Handschin, C., & Eberli, D. (2017) · Cell Transplantation · doi:10.3727/096368917x694868 · Cited by 12

Cancer Immunoprevention and Public Health

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Mild-cold water swimming does not exacerbate white adipose tissue browning and brown adipose tissue activation in mice

da Silva, J. T., Cella, P. S., Testa, M. T. D. J., Perandini, L. A., Festuccia, W. T., Deminice, R., & Chimin, P. (2020) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-020-00771-z · Cited by 12

Extended Sedentary Time Increases the Risk of All-Cause Death and New Cardiovascular Events in Patients With Diabetic Kidney Disease

Tamiya, H., Tamura, Y., Mochi, S., Akazawa, Y., Mochi, Y., Banba, N., Nakatani, Y., Hoshiai, M., Ueno, A., Nagao, M., et al. (2020) · Circulation Journal · doi:10.1253/circj.cj-20-0407 · Cited by 12

Exercise-modulated IL-6 in cancer cachexia: molecular mechanisms and therapeutic potential

Wei, S., Lv, X., Xu, Y., & Ding, S. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07690-5 · Cited by 12

Synthetic Activators of Autophagy

Guseva, E. A., Pavlova, J. A., Dontsova, O. А., & Владимирович, С. П. (2024) · Biochemistry (Moscow) · doi:10.1134/s0006297924010024 · Cited by 11

Fully printed multimodal sensing system for continuous health monitoring during exercise

Zhu, B., Zhu, L., Wang, H., Li, X., Zhao, Z., Zhou, L., Gao, Z., Hu, N., & Su, B. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117840 · Cited by 11

Microvascular Adaptations to Exercise: Protective Effect of PGC-1 Alpha

Kadlec, A. O., Barnes, C. A., Durand, M. J., & Gutterman, D. D. (2017) · American Journal of Hypertension · doi:10.1093/ajh/hpx162 · Cited by 12

The Pivotal Role of Adipocyte-Na K peptide in Reversing Systemic Inflammation in Obesity and COVID-19 in the Development of Heart Failure

Xie, Z.-J., Novograd, J., Itzkowitz, Y., Sher, A., Buchen, Y. D., Sodhi, K., Abraham, N. G., & Shapiro, J. I. (2020) · Antioxidants · doi:10.3390/antiox9111129 · Cited by 11

Citrus hassaku Extract Powder Increases Mitochondrial Content and Oxidative Muscle Fibers by Upregulation of PGC-1α in Skeletal Muscle

Akashi, S., Morita, A., Mochizuki, Y., Shibuya, F., Kamei, Y., & Miura, S. (2021) · Nutrients · doi:10.3390/nu13020497 · Cited by 11

The Effect of 8 Weeks of Carob Supplementation and Resistance Training on Lipid Profile and Irisin in Obese Men

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VMHdm/cSF-1 neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive

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Peroxisome proliferator-activated receptor gamma co-activator 1 gene Gly482Ser polymorphism is associated with the response of low-density lipoprotein cholesterol concentrations to exercise training in elderly Japanese

Tobina, T., Mori, Y., Doi, Y., Nakayama, F., Kiyonaga, A., & Tanaka, H. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0491-y · Cited by 12

Frailty in Trauma Patients: An Emerging Geriatric Syndrome

Khan, M., & Joseph, B. A. (2017) · Current Surgery Reports · doi:10.1007/s40137-017-0193-2 · Cited by 11

The Molecular Mechanisms and Prevention Principles of Muscle Atrophy in Aging

Zhang, Y., Pan, X., Sun, Y., Geng, Y., Yu, X., & Li, Y. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1435-3_16 · Cited by 11

Effects of aerobic exercise on the inflammatory cytokine profile and expression of lipolytic and thermogenic genes in β1-AR−/− mice adipose tissue

Rodrigues, A. C., Leal, T. F., Costa, A., Silva, F. D. J., Soares, L. L., Brum, P. C., Hermsdorff, H. H. M., Pelúzio, M. D. C. G., Prímola‐Gomes, T. N., & Natali, A. J. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.02.031 · Cited by 11

Effect of Eight Weeks of Aerobic Progressive Training with Capsaicin on Changes in PGC-1α and UPC-1 Expression in Visceral Adipose Tissue of Obese Rats With Diet

Mostafavian, M., Abdi, A., Mehrabani, J., & Barari, A. (2020) · Complementary Medicine Journal · doi:10.32598/cmja.10.2.627.4 · Cited by 11

Exercise and PGC-1α in inflammation and chronic disease

Furrer, R., & Handschin, C. (2015) · German Journal of Sports Medicine · doi:10.5960/dzsm.2015.185 · Cited by 3

PGC-1α-mediated adaptations in skeletal muscle

Olesen, J., Kiilerich, K., & Pilegaard, H. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-010-0834-0 · Cited by 244

Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α

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The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells

Eisele, P. S., Salatino, S., Sobek, J., Hottiger, M. O., & Handschin, C. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.375253 · Cited by 187

Peroxisome proliferator‐activated receptor‐γ coactivator‐1α in muscle links metabolism to inflammation

Handschin, C. (2009) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2009.05275.x · Cited by 39