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Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids
Open accessAbstract
Segregating hybrids and stable allopolyploids display morphological vigour, and Arabidopsis allotetraploids are larger than the parents Arabidopsis thaliana and Arabidopsis arenosa—the mechanisms for this are unknown. Circadian clocks mediate metabolic pathways and increase fitness in animals and plants. Here we report that epigenetic modifications of the circadian clock genes CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) and their reciprocal regulators TIMING OF CAB EXPRESSION 1 (TOC1) and GIGANTEA (GI) mediate expression changes in downstream genes and pathways. During the day, epigenetic repression of CCA1 and LHY induced the expression of TOC1, GI and downstream genes containing evening elements in chlorophyll and starch metabolic pathways in allotetraploids and F1 hybrids, which produced more chlorophyll and starch than the parents in the same environment. Mutations in cca1 and cca1 lhy and the daily repression of cca1 by RNA interference (RNAi) in TOC1::cca1(RNAi) transgenic plants increased the expression of downstream genes and increased chlorophyll and starch content, whereas constitutively expressing CCA1 or ectopically expressing TOC1::CCA1 had the opposite effect. The causal effects of CCA1 on output traits suggest that hybrids and allopolyploids gain advantages from the control of circadian-mediated physiological and metabolic pathways, leading to growth vigour and increased biomass.
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Cites
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
Initiative, T. A. G. (2000) · Nature · doi:10.1038/35048692 · Cited by 9,301
Cited by
Abbott, R., Albach, D., Ansell, S., Arntzen, J. W., Baird, S. J. E., Bierne, N., Boughman, J., Brelsford, A., Buerkle, C. A., Buggs, R., et al. (2013) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2012.02599.x · Cited by 2,194
Gene duplication and evolutionary novelty in plants
Flagel, L. E., & Wendel, J. F. (2009) · New Phytologist · doi:10.1111/j.1469-8137.2009.02923.x · Cited by 969
Global Epigenetic and Transcriptional Trends among Two Rice Subspecies and Their Reciprocal Hybrids
He, G., Zhu, X., Elling, A. A., Chen, L., Wang, X., Guo, L., Liang, M., He, H., Zhang, H., Chen, F., et al. (2010) · The Plant Cell · doi:10.1105/tpc.109.072041 · Cited by 561
Borland, A. M., Griffiths, H., Hartwell, J., & Smith, J. A. C. (2009) · Journal of Experimental Botany · doi:10.1093/jxb/erp118 · Cited by 371
Polyploidy, the Nucleotype, and Novelty: The Impact of Genome Doubling on the Biology of the Cell
Doyle, J. J., & Coate, J. E. (2019) · International Journal of Plant Sciences · doi:10.1086/700636 · Cited by 365
Metadata
- Authors
- Ni, Z., Kim, E.-D., Ha, M., Lackey, E., Liu, J., Zhang, Y., Sun, Q., & Chen, Z. J.
- Venue
- Nature
- Published
- 2008-11-23
- Volume
- 457
- Issue
- 7227
- Pages
- 327-331
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2040528706
- Cited by
- 677
- References
- 1
- FWCI
- 40.11
- Type
- journal article
- Language
- en
- Open access
- green
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- Ni, Z., Kim, E.-D., Ha, M., Lackey, E., Liu, J., Zhang, Y., Sun, Q., & Chen, Z. J. (2009). Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids. Nature. https://doi.org/10.1038/nature07523
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