The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Functional complexity and regulation through RNA dynamics
Open accessAbstract
Changes to the conformation of coding and non-coding RNAs form the basis of elements of genetic regulation and provide an important source of complexity, which drives many of the fundamental processes of life. Although the structure of RNA is highly flexible, the underlying dynamics of RNA are robust and are limited to transitions between the few conformations that preserve favourable base-pairing and stacking interactions. The mechanisms by which cellular processes harness the intrinsic dynamic behaviour of RNA and use it within functionally productive pathways are complex. The versatile functions and ease by which it is integrated into a wide variety of genetic circuits and biochemical pathways suggests there is a general and fundamental role for RNA dynamics in cellular processes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Spliceosome Structure and Function
Will, C. L., & Luhrmann, R. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003707 · Cited by 1,829
The Mechanism for Activation of GTP Hydrolysis on the Ribosome
Voorhees, R. M., Schmeing, T. M., Kelley, A. C., & Ramakrishnan, V. (2010) · Science · doi:10.1126/science.1194460 · Cited by 366
Abbink, T. E. M., Ooms, M., Haasnoot, P. C. J., & Berkhout, B. (2005) · Biochemistry · doi:10.1021/bi0502588 · Cited by 122
Cited by
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
Lu, Z., Zhang, Q. C., Lee, B., Flynn, R. A., Smith, M. A., Robinson, J. T., Davidovich, C., Gooding, A. R., Goodrich, K. J., Mattick, J. S., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.028 · Cited by 656
RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
Siegfried, N. A., Busan, S., Rice, G. M., Nelson, J. A. E., & Weeks, K. M. (2014) · Nature Methods · doi:10.1038/nmeth.3029 · Cited by 654
Briggs, J. A., Wolvetang, E. J., Mattick, J. S., Rinn, J. L., & Barry, G. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.045 · Cited by 447
Smola, M. J., Rice, G. M., Busan, S., Siegfried, N. A., & Weeks, K. M. (2015) · Nature Protocols · doi:10.1038/nprot.2015.103 · Cited by 398
Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity
Shabalina, S. A., Spiridonov, N. A., & Kashina, A. (2013) · Nucleic Acids Research · doi:10.1093/nar/gks1205 · Cited by 291
Metadata
- Authors
- Dethoff, E. A., Chugh, J., Mustoe, A. M., & Al-Hashimi, H. M.
- Venue
- Nature
- Published
- 2012-02-15
- Volume
- 482
- Issue
- 7385
- Pages
- 322-330
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2030394302
- Cited by
- 328
- References
- 3
- FWCI
- 13.13
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Functional complexity and regulation through RNA dynamics. https://app.cochat.ai/papers/10.1038/nature10885
- The paper
- Dethoff, E. A., Chugh, J., Mustoe, A. M., & Al-Hashimi, H. M. (2012). Functional complexity and regulation through RNA dynamics. Nature. https://doi.org/10.1038/nature10885
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
