The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Choice-specific sequences in parietal cortex during a virtual-navigation decision task
Open accessAbstract
The posterior parietal cortex (PPC) has an important role in many cognitive behaviours; however, the neural circuit dynamics underlying PPC function are not well understood. Here we optically imaged the spatial and temporal activity patterns of neuronal populations in mice performing a PPC-dependent task that combined a perceptual decision and memory-guided navigation in a virtual environment. Individual neurons had transient activation staggered relative to one another in time, forming a sequence of neuronal activation spanning the entire length of a task trial. Distinct sequences of neurons were triggered on trials with opposite behavioural choices and defined divergent, choice-specific trajectories through a state space of neuronal population activity. Cells participating in the different sequences and at distinct time points in the task were anatomically intermixed over microcircuit length scales (<100 micrometres). During working memory decision tasks, the PPC may therefore perform computations through sequence-based circuit dynamics, rather than long-lived stable states, implemented using anatomically intermingled microcircuits.
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Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
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Using goal-driven deep learning models to understand sensory cortex
Yamins, D. L. K., & DiCarlo, J. J. (2016) · Nature Neuroscience · doi:10.1038/nn.4244 · Cited by 1,621
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A Cortical Circuit for Gain Control by Behavioral State
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“Recent advances in mouse genetics and in vivo imaging technology now allow one to characterize the responses of different types of inhibitory neurons in the mouse V1 in awake animals that are free to run (Dombeck et al., 2010; Harvey et al., 2012; Taniguchi et al., 2011).”
Background
Metadata
- Authors
- Harvey, C. D., Coen, P., & Tank, D. W.
- Venue
- Nature
- Published
- 2012-03-14
- Volume
- 484
- Issue
- 7392
- Pages
- 62-68
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1977906889
- Cited by
- 931
- References
- 50
- FWCI
- 25.95
- Type
- journal article
- Language
- en
- Open access
- green
- Licence
- www.springer.com/tdm (tdm)
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