Memory, navigation and theta rhythm in the hippocampal-entorhinal system
Open accessAbstract
Theories on the functions of the hippocampal system are based largely on two fundamental discoveries: the amnestic consequences of removing the hippocampus and associated structures in the famous patient H.M. and the observation that spiking activity of hippocampal neurons is associated with the spatial position of the rat. In the footsteps of these discoveries, many attempts were made to reconcile these seemingly disparate functions. Here we propose that mechanisms of memory and planning have evolved from mechanisms of navigation in the physical world and hypothesize that the neuronal algorithms underlying navigation in real and mental space are fundamentally the same. We review experimental data in support of this hypothesis and discuss how specific firing patterns and oscillatory dynamics in the entorhinal cortex and hippocampus can support both navigation and memory.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Theta oscillations are not necessary for the emergence of the place code but play a major role in organizing place cell activity into temporal sequences that map available space and episodic events.
“Theta oscillations—although not necessary for the emergence of the place code21,22—play a major role in organizing place cell activity into temporal sequences that map the available space (and, similarly, episodic events4,23,24).”
From Place and behavioral modulation of hippocampal neurons during immobility (2026) · cites this paper as [23]
In “Challenges and questions” (page unavailable), the paper describes place and grid cells without apparent theta modulation, supporting the point that theta is not necessary for a place code. “The multiple-timescale organization of neuronal assemblies” describes theta-organized place-cell sequences representing past, current and future positions. For episodic events, however, “Temporal organization of exploration and episodic memory” says the authors *suggest* that theta-enabled assembly organization could support episodic recall; the claim presents that proposed role more definitively. (LLM, conf=0.82)
Experimental — accuracy not yet measuredIn mammals, allocentric navigation involves an extended cortico-hippocampal network that conveys highly processed visual and multisensory information to hippocampal circuits for transformation into 'world-centered' relational spatial representations.
“In mammals, allocentric navigation is thought to involve the operation of an extended cortico-hippocampal network that conveys highly processed visual and multisensory information to the hippocampal circuits for further processing and transformation into “world-centered” relational spatial representations [74,76,79,188,189,190,191,192].”
From Spatial Cognition in Teleost Fish: Strategies and Mechanisms (2021) · cites this paper as [188]
The Abstract describes allocentric navigation as using spatial relationships among landmarks, and ‘Allocentric maps and semantic memory’ describes entorhinal–hippocampal circuits representing spatial relationships. ‘Challenges and questions’ says the entorhinal cortex drives hippocampal circuits during navigation partly using external cues. Our copy does not establish the more specific claim that an extended cortical network conveys highly processed visual and multisensory information to those circuits. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe observation that CA1 pyramidal cell activity is systematically biased by the animal's location supports the view that space is a fundamental dimension encoded within the hippocampal cognitive map.
“This observation supports the view that space is a fundamental dimension encoded within the hippocampal cognitive map23,80.”
From Place and behavioral modulation of hippocampal neurons during immobility (2026) · cites this paper as [23]
The hippocampus supports goal-directed learning and behaviour and also supports other advanced cognitive abilities that require prospection.
“The ability of the hippocampus to support goal-directed learning and behaviour has been studied principally in spatial navigation (Buzsáki and Moser, 2013), but evidence suggests that this area also supports other advanced cognitive abilities that require prospection, such as imagination of fictive scenarios (Hassabis and Maguire, 2009).”
From Active Inference, homeostatic regulation and adaptive behavioural control (2015) · cites this paper as Buzsáki and Moser, 2013
In some simple models, targeted navigation in the hippocampus is achieved via the dynamics of bump attractors or propagating waves in a place cell network with Hebbian plasticity and adaptation.
“In some simple models, targeted navigation in the hippocampus is achieved via the dynamics of “bump attractors” or propagating waves in a place cell network with Hebbian plasticity and adaptation (Hopfield, 2009; Buzsáki and Moser, 2013; Ponulak and Hopfield, 2013)”
From Toward an integration of deep learning and neuroscience (2016) · cites this paper as Buzsáki and Moser, 2013
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
(1978) · UA Campus Repository (The University of Arizona) · Cited by 8,010 · see citing works
LOSS OF RECENT MEMORY AFTER BILATERAL HIPPOCAMPAL LESIONS
Scoville, W. B., & Milner, B. (1957) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.20.1.11 · Cited by 7,322 · see citing works
Construal-level theory of psychological distance.
Trope, Y., & Liberman, N. (2010) · Psychological Review · doi:10.1037/a0018963 · Cited by 6,618 · see citing works
Neuronal Oscillations in Cortical Networks
Buzsáki, G., & Draguhn, A. (2004) · Science · doi:10.1126/science.1099745 · Cited by 6,576 · see citing works
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
Squire, L. R. (1992) · Psychological Review · doi:10.1037/0033-295x.99.2.195 · Cited by 5,376 · see citing works
McClelland, J. L., McNaughton, B. L., & O'Reilly, R. C. (1995) · Psychological Review · doi:10.1037/0033-295x.102.3.419 · Cited by 5,256 · see citing works
Microstructure of a spatial map in the entorhinal cortex
Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., & Moser, E. I. (2005) · Nature · doi:10.1038/nature03721 · Cited by 4,068 · see citing works
Self-citationMechanisms of Gamma Oscillations
Buzsáki, G., & Wang, X.-J. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150444 · Cited by 2,796 · see citing works
Self-citationBuckner, R. L., & Carroll, D. C. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.11.004 · Cited by 2,691 · see citing works
High Gamma Power Is Phase-Locked to Theta Oscillations in Human Neocortex
Canolty, R. T., Edwards, E., Dalal, S. S., Soltani, M., Nagarajan, S. S., Kirsch, H. E., Berger, M. S., Barbaro, N. M., & Knight, R. T. (2006) · Science · doi:10.1126/science.1128115 · Cited by 2,650 · see citing works
Phase relationship between hippocampal place units and the EEG theta rhythm
O'Keefe, J. M., & Recce, M. L. (1993) · Hippocampus · doi:10.1002/hipo.450030307 · Cited by 2,561 · see citing works
The human hippocampus and spatial and episodic memory
Burgess, N., Maguire, E. A., & O'Keefe, J. (2002) · Neuron · doi:10.1016/s0896-6273(02)00830-9 · Cited by 2,401 · see citing works
Dynamics of the Hippocampal Ensemble Code for Space
Wilson, M. A., & McNaughton, B. L. (1993) · Science · doi:10.1126/science.8351520 · Cited by 2,350 · see citing works
The evolution of foresight: What is mental time travel, and is it unique to humans?
Suddendorf, T., & Corballis, M. C. (2007) · Behavioral and Brain Sciences · doi:10.1017/s0140525x07001975 · Cited by 2,031 · see citing works
Path integration and the neural basis of the 'cognitive map'
McNaughton, B. L., Battaglia, F. P., Jensen, O., Moser, E. I., & Moser, M.-B. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1932 · Cited by 2,024 · see citing works
Self-citationInvariant visual representation by single neurons in the human brain
Quiroga, R. Q., Reddy, L., Kreiman, G., Koch, C., & Fried, I. (2005) · Nature · doi:10.1038/nature03687 · Cited by 1,988 · see citing works
Place Cells, Grid Cells, and the Brain's Spatial Representation System
Moser, E. I., Kropff, E., & Moser, M.-B. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.061307.090723 · Cited by 1,934 · see citing works
Self-citationMemory consolidation, retrograde amnesia and the hippocampal complex
Nadel, L., & Moscovitch, M. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80010-4 · Cited by 1,924 · see citing works
Principles of Frontal Lobe Function
Stuss, D. T. (2002) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195134971.001.0001 · Cited by 1,708 · see citing works
Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus
Leutgeb, J. K., Leutgeb, S., Moser, M.-B., & Moser, E. I. (2007) · Science · doi:10.1126/science.1135801 · Cited by 1,601 · see citing works
Self-citationThe effects of changes in the environment on the spatial firing of hippocampal complex-spike cells
Muller, R., & Kubie, J. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-07-01951.1987 · Cited by 1,581 · see citing works
Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat
Bragin, A., Jando, G., Nadasdy, Z., Hetke, J., Wise, K., & Buzsaki, G. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00047.1995 · Cited by 1,527 · see citing works
Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex
Sargolini, F., Fyhn, M., Hafting, T., McNaughton, B. L., Witter, M. P., Moser, M.-B., & Moser, E. I. (2006) · Science · doi:10.1126/science.1125572 · Cited by 1,485 · see citing works
Self-citationStorage of 7 +/- 2 short-term memories in oscillatory subcycles
Lisman, J. E., & Idiart, M. A. P. (1995) · Science · doi:10.1126/science.7878473 · Cited by 1,471 · see citing works
Frequency of gamma oscillations routes flow of information in the hippocampus
Colgin, L. L., Denninger, T., Fyhn, M., Hafting, T., Bonnevie, T., Jensen, O. B., Moser, M., & Moser, E. I. (2009) · Nature · doi:10.1038/nature08573 · Cited by 1,425 · see citing works
Self-citationInternally Generated Cell Assembly Sequences in the Rat Hippocampus
Pastalkova, E., Itskov, V., Amarasingham, A., & Buzsáki, G. (2008) · Science · doi:10.1126/science.1159775 · Cited by 1,301 · see citing works
Neural syntax: cell assemblies, synapsembles, and readers
Buzsáki, G. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.023 · Cited by 1,289 · see citing works
Self-citationComputational analysis of the role of the hippocampus in memory
Treves, A., & Rolls, E. T. (1994) · Hippocampus · doi:10.1002/hipo.450040319 · Cited by 1,272 · see citing works
Representation of Geometric Borders in the Entorhinal Cortex
Solstad, T., Boccara, C. N., Kropff, E., Moser, M.-B., & Moser, E. I. (2008) · Science · doi:10.1126/science.1166466 · Cited by 1,213 · see citing works
Self-citationHippocampal ‘time cells’ bridge the gap in memory for discontiguous events
MacDonald, C. J., Lepage, K. Q., Eden, U. T., & Eichenbaum, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.012 · Cited by 1,193 · see citing works
Geometric determinants of the place fields of hippocampal neurons
O'Keefe, J., & Burgess, N. (1996) · Nature · doi:10.1038/381425a0 · Cited by 1,166 · see citing works
Radical embodiment: neural dynamics and consciousness
Thompson, E., & Varela, F. J. (2001) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01750-2 · Cited by 1,144 · see citing works
McNaughton, B. L., Barnes, C. A., & O'Keefe, J. (1983) · Experimental Brain Research · doi:10.1007/bf00237147 · Cited by 1,071 · see citing works
The Hippocampus, Memory, and Place Cells
Eichenbaum, H., Dudchenko, P., Wood, E., Shapiro, M., & Tanila, H. (1999) · Neuron · doi:10.1016/s0896-6273(00)80773-4 · Cited by 1,064 · see citing works
Neural ensembles in CA3 transiently encode paths forward of the animal at a decision point
Johnson, A., & Redish, A. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3761-07.2007 · Cited by 1,003 · see citing works
Wood, E. R., Dudchenko, P. A., Robitsek, R. J., & Eichenbaum, H. (2000) · Neuron · doi:10.1016/s0896-6273(00)00071-4 · Cited by 992 · see citing works
Inhibition-based rhythms: experimental and mathematical observations on network dynamics
Whittington, M. A., Traub, R. D., Kopell, N., Ermentrout, B., & Buhl, E. (2000) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(00)00173-2 · Cited by 953 · see citing works
Cross-frequency coupling supports multi-item working memory in the human hippocampus
Axmacher, N., Henseler, M. M., Jensen, O. B., Weinreich, I., Elger, C. E., & Fell, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911531107 · Cited by 929 · see citing works
Theta-gamma coupling increases during the learning of item-context associations
Tort, A. B. L., Komorowski, R. W., Manns, J. R., Kopell, N. J., & Eichenbaum, H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911331106 · Cited by 919 · see citing works
Choice-specific sequences in parietal cortex during a virtual-navigation decision task
Harvey, C. D., Coen, P., & Tank, D. W. (2012) · Nature · doi:10.1038/nature10918 · Cited by 916 · see citing works
Deciphering The Hippocampal Polyglot: the Hippocampus as a Path Integration System
McNaughton, B. L., Barnes, C. A., Gerrard, J. L., Gothard, K. M., Jung, M. W., Knierim, J. J., Kudrimoti, H. S., Qin, Y., Skaggs, W. E., Suster, M. S., et al. (1996) · Journal of Experimental Biology · doi:10.1242/jeb.199.1.173 · Cited by 900 · see citing works
Buzsáki, G. (2005) · Hippocampus · doi:10.1002/hipo.20113 · Cited by 872 · see citing works
Self-citationOrganization of cell assemblies in the hippocampus
Harris, K. D., Csicsvari, J. L., Hirase, H., Dragoi, G., & Buzsáki, G. (2003) · Nature · doi:10.1038/nature01834 · Cited by 869 · see citing works
Self-citationNakashiba, T., Cushman, J. D., Pelkey, K. A., Renaudineau, S., Buhl, D. L., McHugh, T. J., Barrera, V. R., Chittajallu, R., Iwamoto, K. S., McBain, C. J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.01.046 · Cited by 805 · see citing works
Distinct Ensemble Codes in Hippocampal Areas CA3 and CA1
Leutgeb, S., Leutgeb, J. K., Treves, A., Moser, M., & Moser, E. I. (2004) · Science · doi:10.1126/science.1100265 · Cited by 774 · see citing works
Self-citationFinite scale of spatial representation in the hippocampus
Kjelstrup, K. B., Solstad, T., Brun, V. H., Hafting, T., Leutgeb, S., Witter, M. P., Moser, E. I., & Moser, M.-B. (2008) · Science · doi:10.1126/science.1157086 · Cited by 760 · see citing works
Self-citationThe hippocampal CA3 network: An in vivo intracellular labeling study
Li, X. ‐., Somogyi, P., Ylinen, A., & Buzsáki, G. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903390204 · Cited by 751 · see citing works
Self-citationHippocampal remapping and grid realignment in entorhinal cortex
Fyhn, M., Hafting, T., Treves, A., Moser, M.-B., & Moser, E. I. (2007) · Nature · doi:10.1038/nature05601 · Cited by 749 · see citing works
Self-citationTrajectory Encoding in the Hippocampus and Entorhinal Cortex
Frank, L. M., Brown, E. N., & Wilson, M. A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00018-0 · Cited by 731 · see citing works
Control of timing, rate and bursts of hippocampal place cells by dendritic and somatic inhibition
Royer, S., Zemelman, B. V., Losonczy, A., Kim, J., Chance, F., Magee, J. C., & Buzsáki, G. (2012) · Nature Neuroscience · doi:10.1038/nn.3077 · Cited by 728 · see citing works
Self-citationTemporal Encoding of Place Sequences by Hippocampal Cell Assemblies
Dragoi, G., & Buzsáki, G. (2006) · Neuron · doi:10.1016/j.neuron.2006.02.023 · Cited by 727 · see citing works
Self-citationMizuseki, K., Sirota, A., Pastalkova, E., & Buzsáki, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.037 · Cited by 718 · see citing works
Self-citationThe entorhinal grid map is discretized
Stensola, H., Stensola, T., Solstad, T., Frøland, K., Moser, M., & Moser, E. I. (2012) · Nature · doi:10.1038/nature11649 · Cited by 706 · see citing works
Self-citationBehavior-dependent short-term assembly dynamics in the medial prefrontal cortex
Fujisawa, S., Amarasingham, A., Harrison, M. T., & Buzsáki, G. (2008) · Nature Neuroscience · doi:10.1038/nn.2134 · Cited by 679 · see citing works
Self-citationThe hippocampus and memory for orderly stimulus relations
Dusek, J. A., & Eichenbaum, H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.13.7109 · Cited by 610 · see citing works
Relating Hippocampal Circuitry to Function
Lisman, J. E. (1999) · Neuron · doi:10.1016/s0896-6273(00)81085-5 · Cited by 607 · see citing works
Grid cells in pre- and parasubiculum
Boccara, C. N., Sargolini, F., Thoresen, V. H., Solstad, T., Witter, M. P., Moser, E. I., & Moser, M. (2010) · Nature Neuroscience · doi:10.1038/nn.2602 · Cited by 527 · see citing works
Self-citationGothard, K., Skaggs, W. E., Moore, K. L., & McNaughton, B. L. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00823.1996 · Cited by 488 · see citing works
Recognition memory and the human hippocampus.
Manns, J., Hopkins, R., Reed, J. M., Kitchener, E. G., & Squire, L. (2003) · Neuron · doi:10.1016/s0896-6273(02)01147-9 · Cited by 472 · see citing works
Hippocampal sequence-encoding driven by a cortical multi-item working memory buffer
Jensen, O. B., & Lisman, J. E. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.12.001 · Cited by 467 · see citing works
Long-term plasticity in hippocampal place-cell representation of environmental geometry
Lever, C., Wills, T., Cacucci, F., Burgess, N., & O'Keefe, J. (2002) · Nature · doi:10.1038/416090a · Cited by 465 · see citing works
The Role of the Hippocampus in Prediction and Imagination
Buckner, R. L. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163508 · Cited by 419 · see citing works
Human hippocampal theta activity during virtual navigation
Ekstrom, A. D., Caplan, J. B., Ho, E. V., Shattuck, K., Fried, I., & Kahana, M. J. (2005) · Hippocampus · doi:10.1002/hipo.20109 · Cited by 411 · see citing works
Grid cells without theta oscillations in the entorhinal cortex of bats
Yartsev, M. M., Witter, M. P., & Ulanovsky, N. (2011) · Nature · doi:10.1038/nature10583 · Cited by 398 · see citing works
Contextual variability and serial position effects in free recall.
Howard, M. W., & Kahana, M. J. (1999) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037//0278-7393.25.4.923 · Cited by 393 · see citing works
The hippocampus as a cognitive graph.
Muller, R. U., Stead, M., & Pach, J. (1996) · The Journal of general physiology · doi:10.1085/jgp.107.6.663 · Cited by 391 · see citing works
Object and Place Memory in the Macaque Entorhinal Cortex
SUZUKI, W. A., Miller, E. K., & Desimone, R. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.2.1062 · Cited by 383 · see citing works
The Spatial Periodicity of Grid Cells Is Not Sustained During Reduced Theta Oscillations
Koenig, J., Linder, A. N., Leutgeb, J. K., & Leutgeb, S. (2011) · Science · doi:10.1126/science.1201685 · Cited by 378 · see citing works
Neuronal code for extended time in the hippocampus
Mankin, E. A., Sparks, F. T., Slayyeh, B., Sutherland, R. J., Leutgeb, S., & Leutgeb, J. K. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1214107109 · Cited by 371 · see citing works
Theta-paced flickering between place-cell maps in the hippocampus
Jezek, K., Henriksen, E. J., Treves, A., Moser, E. I., & Moser, M.-B. (2011) · Nature · doi:10.1038/nature10439 · Cited by 359 · see citing works
Self-citationKumaran, D., & McClelland, J. L. (2012) · Psychological Review · doi:10.1037/a0028681 · Cited by 358 · see citing works
Segmentation of spatial experience by hippocampal theta sequences
Gupta, A. S., van der Meer, M. A. A., Touretzky, D. S., & Redish, A. D. (2012) · Nature Neuroscience · doi:10.1038/nn.3138 · Cited by 352 · see citing works
Distinct Representations and Theta Dynamics in Dorsal and Ventral Hippocampus
Royer, S., Sirota, A., Patel, J., & Buzsáki, G. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4681-09.2010 · Cited by 351 · see citing works
Self-citationFragmentation of grid cell maps in a multicompartment environment
Derdikman, D., Whitlock, J. R., Tsao, A., Fyhn, M., Hafting, T., Moser, M.-B., & Moser, E. I. (2009) · Nature Neuroscience · doi:10.1038/nn.2396 · Cited by 330 · see citing works
Self-citationOn the directional firing properties of hippocampal place cells
Muller, R., Bostock, E., Taube, J., & Kubie, J. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-12-07235.1994 · Cited by 322 · see citing works
Cognitive Memory: Cellular and Network Machineries and Their Top-Down Control
Miyashita, Y. (2004) · Science · doi:10.1126/science.1101864 · Cited by 314 · see citing works
Contextual variability and serial position effects in free recall.
Howard, M. W., & Kahana, M. J. (1999) · Journal of Experimental Psychology Learning Memory and Cognition · doi:10.1037/0278-7393.25.4.923 · Cited by 313 · see citing works
Knierim, J. J., Kudrimoti, H. S., & McNaughton, B. L. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.425 · Cited by 297 · see citing works
An Experimental Study of Graph Connectivity for Unsupervised Word Sense Disambiguation
Roberto Navigli, A., & Lapata, M. (2009) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.2009.36 · Cited by 288 · see citing works
Hippocampal cellular and network activity in freely moving echolocating bats
Ulanovsky, N., & Moss, C. F. (2007) · Nature Neuroscience · doi:10.1038/nn1829 · Cited by 283 · see citing works
Neural encoding of individual words and faces by the human hippocampus and amygdala
Heit, G., Smith, M. E., & Halgren, E. (1988) · Nature · doi:10.1038/333773a0 · Cited by 281 · see citing works
Hippocampal place cell assemblies are speed-controlled oscillators
Geisler, C. E., Robbe, D., Zugaro, M., Sirota, A., & Buzsáki, G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610121104 · Cited by 273 · see citing works
Self-citationIntegrating what and when across the primate medial temporal lobe
Naya, Y., & Suzuki, W. A. (2011) · Science · doi:10.1126/science.1206773 · Cited by 257 · see citing works
A Brief History of Time (Constants)
Koch, C., Rapp, M., & Segev, I. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.2.93 · Cited by 233 · see citing works
Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons
Mizuseki, K., Royer, S., Diba, K., & Buzsáki, G. (2012) · Hippocampus · doi:10.1002/hipo.22002 · Cited by 221 · see citing works
Self-citationModels of place and grid cell firing and theta rhythmicity
Burgess, N., & O'Keefe, J. M. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.07.002 · Cited by 193 · see citing works
Neural Representations of Location Composed of Spatially Periodic Bands
Krupic, J., Burgess, N., & O’Keefe, J. (2012) · Science · doi:10.1126/science.1222403 · Cited by 182 · see citing works
Chronesthesia: Conscious Awareness of Subjective Time
Tulving, E. (2002) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195134971.003.0020 · Cited by 176 · see citing works
How we remember: brain mechanisms of episodic memory
(2012) · Choice Reviews Online · doi:10.5860/choice.49-5040 · Cited by 147 · see citing works
Diba, K., & Buzsáki, G. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3824-08.2008 · Cited by 145 · see citing works
Self-citationGeisler, C. E., Diba, K., Pastalkova, E., Mizuseki, K., Royer, S., & Buzsáki, G. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0912478107 · Cited by 142 · see citing works
Self-citationBuhl, E. H., Szil�gyi, T., Halasy, K., & Somogyi, P. (1996) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:3 · Cited by 138 · see citing works
Bees travel novel homeward routes by integrating separately acquired vector memories
Menzel, R., Geiger, K., Joerges, J., Müller, U., & Chıttka, L. (1998) · Animal Behaviour · doi:10.1006/anbe.1997.0574 · Cited by 136 · see citing works
Maurer, A. P., Cowen, S. L., Burke, S. N., Barnes, C. A., & McNaughton, B. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2882-06.2006 · Cited by 129 · see citing works
Shrager, Y., Kirwan, C. B., & Squire, L. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0805414105 · Cited by 109 · see citing works
Griesmayr, B., Gruber, W. R., Klimesch, W., & Sauseng, P. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.09.013 · Cited by 82 · see citing works
Webs, cell assemblies, and chunking in neural nets: Introduction.
Wickelgren, W. A. (1999) · Canadian Journal of Experimental Psychology/Revue canadienne de psychologie expérimentale · doi:10.1037/h0087304 · Cited by 66 · see citing works
Theta-Mediated Dynamics of Spatial Information in Hippocampus
Itskov, V., Pastalkova, E., Mizuseki, K., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5262-07.2008 · Cited by 62 · see citing works
The Interaction of Rhinal Cortex and Hippocampus in Human Declarative Memory Formation
Fell, J., Klaver, P., Elger, C. E., & Fernández, G. (2002) · Reviews in the Neurosciences · doi:10.1515/revneuro.2002.13.4.299 · Cited by 55 · see citing works
Hasselmo, M. E. (2011) · The MIT Press eBooks · doi:10.7551/mitpress/9780262016353.001.0001 · Cited by 40 · see citing works
Hasselmo, M. E. (2007) · Learning & Memory · doi:10.1101/lm.686607 · Cited by 35 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Hippocampal sharp wave-ripple: A cognitive biomarker for episodic memory and planning
Buzsáki, G. (2015) · Hippocampus · doi:10.1002/hipo.22488 · Cited by 1,759 · see citing works
Self-citationFunctional organization of the hippocampal longitudinal axis
Strange, B. A., Witter, M. P., Lein, E. S., & Moser, E. I. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3785 · Cited by 1,738 · see citing works
Self-citationThe Molecular and Systems Biology of Memory
Kandel, E. R., Dudai, Y., & Mayford, M. R. (2014) · Cell · doi:10.1016/j.cell.2014.03.001 · Cited by 1,134 · see citing works
Episodic memory and beyond: the hippocampus and neocortex in transformation
Moscovitch, M., Cabeza, R., Winocur, G., & Nadel, L. (2016) · Annual Review of Psychology · doi:10.1146/annurev-psych-113011-143733 · Cited by 1,062 · see citing works
Long-axis specialization of the human hippocampus
Poppenk, J., Evensmoen, H. R., Moscovitch, M., & Nadel, L. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.03.005 · Cited by 1,100 · see citing works
Organizing conceptual knowledge in humans with a gridlike code
Constantinescu, A. O., O’Reilly, J. X., & Behrens, T. E. J. (2016) · Science · doi:10.1126/science.aaf0941 · Cited by 937 · see citing works
The cognitive map in humans: spatial navigation and beyond
Epstein, R. A., Patai, E. Z., Julian, J. B., & Spiers, H. J. (2017) · Nature Neuroscience · doi:10.1038/nn.4656 · Cited by 921 · see citing works
Basso, J. C., & Suzuki, W. A. (2016) · Brain Plasticity · doi:10.3233/bpl-160040 · Cited by 911 · see citing works
Time cells in the hippocampus: a new dimension for mapping memories
Eichenbaum, H. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3827 · Cited by 843 · see citing works
Viewpoints: how the hippocampus contributes to memory, navigation and cognition
Lisman, J., Buzsáki, G., Eichenbaum, H., Nadel, L., Ranganath, C., & Redish, A. D. (2017) · Nature Neuroscience · doi:10.1038/nn.4661 · Cited by 851 · see citing works
Self-citationMapping of a non-spatial dimension by the hippocampal-entorhinal circuit
Aronov, D., Nevers, R., & Tank, D. W. (2017) · Nature · doi:10.1038/nature21692 · Cited by 773 · see citing works
Shared memories reveal shared structure in neural activity across individuals
Chen, J., Leong, Y. C., Honey, C. J., Yong, C. H., Norman, K. A., & Hasson, U. (2017) · Nature Neuroscience · doi:10.1038/nn.4450 · Cited by 645 · see citing works
What Learning Systems do Intelligent Agents Need? Complementary Learning Systems Theory Updated
Kumaran, D., Hassabis, D., & McClelland, J. L. (2016) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2016.05.004 · Cited by 736 · see citing works
Navigating cognition: Spatial codes for human thinking
Bellmund, J. L. S., Gärdenfors, P., Moser, E. I., & Doeller, C. F. (2018) · Science · doi:10.1126/science.aat6766 · Cited by 643 · see citing works
Self-citationActive Inference, homeostatic regulation and adaptive behavioural control
Pezzulo, G., Rigoli, F., & Friston, K. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.09.001 · Cited by 650 · see citing works
“The ability of the hippocampus to support goal-directed learning and behaviour has been studied principally in spatial navigation (Buzsa´ki and Moser, 2013), but evidence suggests that this area also supports other advanced cognitive abilities that require prospection, such as imagination of fictive…”
The Restless Engram: Consolidations Never End
Dudai, Y. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150500 · Cited by 644 · see citing works
Spatial representation in the hippocampal formation: a history
Moser, E. I., Moser, M.-B., & McNaughton, B. L. (2017) · Nature Neuroscience · doi:10.1038/nn.4653 · Cited by 560 · see citing works
Self-citationDirect recordings of grid-like neuronal activity in human spatial navigation
Jacobs, J., Weidemann, C. T., Miller, J. F., Solway, A., Burke, J. F., Wei, X.-X., Suthana, N., Sperling, M. R., Sharan, A. D., Fried, I., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3466 · Cited by 564 · see citing works
Human replay spontaneously reorganizes experience
Liu, Y., Dolan, R. J., Kurth-Nelson, Z., & Behrens, T. E. J. (2019) · Cell · doi:10.1016/j.cell.2019.06.012 · Cited by 497 · see citing works
The hippocampal sharp wave-ripple in memory retrieval for immediate use and consolidation
Joo, H. R., & Frank, L. M. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0077-1 · Cited by 430 · see citing works
The role of the hippocampus in navigation is memory
Eichenbaum, H. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00005.2017 · Cited by 430 · see citing works
Inhibition-induced theta resonance in cortical circuits
Stark, E., Eichler, R., Roux, L., Fujisawa, S., Rotstein, H. G., & Buzsáki, G. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.033 · Cited by 326 · see citing works
Self-citationOscillatory multiplexing of population codes for selective communication in the mammalian brain
Akam, T., & Kullmann, D. M. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3668 · Cited by 327 · see citing works
The evolution of episodic memory
Allen, T. A., & Fortin, N. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1301199110 · Cited by 350 · see citing works
CA1 pyramidal cell diversity enabling parallel information processing in the hippocampus
Soltesz, I., & Losonczy, A. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0118-0 · Cited by 333 · see citing works
How the hippocampus preserves order: the role of prediction and context
Davachi, L., & DuBrow, S. (2015) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2014.12.004 · Cited by 328 · see citing works
Franjic, D., Skarica, M., Ma, S., Arellano, J. I., Tebbenkamp, A. T. N., Choi, J., Xu, C., Li, Q., Morozov, Y. M., Andrijevic, D., et al. (2022) · Neuron · doi:10.1016/j.neuron.2021.10.036 · Cited by 308 · see citing works
Gating of hippocampal activity, plasticity, and memory by entorhinal cortex long-range inhibition
Basu, J., Zaremba, J. D., Cheung, S. K., Hitti, F. L., Zemelman, B. V., Losonczy, A., & Siegelbaum, S. A. (2016) · Science · doi:10.1126/science.aaa5694 · Cited by 274 · see citing works
Sublayer-Specific Coding Dynamics during Spatial Navigation and Learning in Hippocampal Area CA1
Danielson, N. B., Zaremba, J. D., Kaifosh, P., Bowler, J., Ladow, M., & Losonczy, A. (2016) · Neuron · doi:10.1016/j.neuron.2016.06.020 · Cited by 288 · see citing works
Identification of a brainstem circuit regulating visual cortical state in parallel with locomotion
Lee, A. M., Hoy, J. L., Bonci, A., Wilbrecht, L., Stryker, M. P., & Niell, C. M. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.031 · Cited by 282 · see citing works
Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice
Ittner, A., Chua, S. W., Bertz, J., Volkerling, A., van der Hoven, J., Gladbach, A., Przybyla, M., Bi, M., van Hummel, A., Stevens, C. H., et al. (2016) · Science · doi:10.1126/science.aah6205 · Cited by 263 · see citing works
Ekstrom, A. D., Arnold, A. E. G. F., & Iaria, G. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00803 · Cited by 263 · see citing works
Memory: organization and control.
Eichenbaum, H. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-010416-044131 · Cited by 257 · see citing works
Diehl, G. W., Hon, O. J., Leutgeb, S., & Leutgeb, J. K. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.004 · Cited by 204 · see citing works
Planning and navigation as active inference
Kaplan, R., & Friston, K. J. (2018) · Biological Cybernetics · doi:10.1007/s00422-018-0753-2 · Cited by 203 · see citing works
Bezaire, M. J., Raikov, I., Burk, K., Vyas, D., & Soltesz, I. (2016) · eLife · doi:10.7554/elife.18566 · Cited by 198 · see citing works
Perea, G., Gómez, R., Mederos, S., Covelo, A., Ballesteros, J. J., Schlosser, L., Hernández-Vivanco, A., Martín-Fernández, M., Quintana, R., Rayan, A., et al. (2016) · eLife · doi:10.7554/elife.20362 · Cited by 194 · see citing works
Mechanisms of Hypnosis:<i>Toward the Development of a Biopsychosocial Model</i>
Jensen, M. P., Adachi, T., Tomé-Pires, C., Lee, J., Osman, Z. J., & Miró, J. (2015) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2014.961875 · Cited by 202 · see citing works
Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
Yanovsky, Y., Ciatipis, M., Draguhn, A., Tort, A. B. L., & Brankačk, J. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.5287-13.2014 · Cited by 175 · see citing works
Social and novel contexts modify hippocampal CA2 representations of space
Alexander, G. M., Farris, S., Pirone, J. R., Zheng, C., Colgin, L. L., & Dudek, S. M. (2016) · Nature Communications · doi:10.1038/ncomms10300 · Cited by 191 · see citing works
Buzsáki, G., & Llinás, R. (2017) · Science · doi:10.1126/science.aan8869 · Cited by 175 · see citing works
Self-citationTheta Oscillations in the Human Medial Temporal Lobe during Real-World Ambulatory Movement
M. Aghajan, Z., Schuette, P., Fields, T. A., Tran, M. E., Siddiqui, S. M., Hasulak, N. R., Tcheng, T. K., Eliashiv, D., Mankin, E. A., Stern, J., et al. (2017) · Current Biology · doi:10.1016/j.cub.2017.10.062 · Cited by 186 · see citing works
Grid-like processing of imagined navigation
Horner, A. J., Bisby, J. A., Zotow, E., Bush, D., & Burgess, N. (2016) · Current Biology · doi:10.1016/j.cub.2016.01.042 · Cited by 173 · see citing works
EEG and functional ultrasound imaging in mobile rats
Sieu, L.-A., Bergel, A., Tiran, E., Deffieux, T., Pernot, M., Gennisson, J.-L., Tanter, M., & Cohen, I. (2015) · Nature Methods · doi:10.1038/nmeth.3506 · Cited by 158 · see citing works
Brandon, M. P., Koenig, J., Leutgeb, J. K., & Leutgeb, S. (2014) · Neuron · doi:10.1016/j.neuron.2014.04.013 · Cited by 145 · see citing works
Running rewires the neuronal network of adult-born dentate granule cells
Vivar, C., Peterson, B. D., & van Praag, H. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.11.031 · Cited by 143 · see citing works
Lensjø, K. K., Christensen, A. C., Tennøe, S., Fyhn, M., & Hafting, T. (2017) · eneuro · doi:10.1523/eneuro.0379-16.2017 · Cited by 133 · see citing works
Toward an integration of deep learning and neuroscience
Marblestone, A. H., Wayne, G., & Kording, K. P. (2016) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2016.00094 · Cited by 119 · see citing works
Low-dimensional and monotonic preparatory activity in mouse anterior lateral motor cortex
Inagaki, H. K., Inagaki, M., Romani, S., & Svoboda, K. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.3152-17.2018 · Cited by 111 · see citing works
“Such sequences have been reported during motor planning and other kinds of short-term memory in the premotor cortex, the mPFC, the posterior parietal cortex, and the hippocampus of rodents (Harvey et al., 2012; Buzsáki and Moser, 2013; Murakami et al., 2014; Schmitt et al., 2017).”
BackgroundHippocampo-cortical circuits for selective memory encoding, routing, and replay
Harvey, R. E., Robinson, H. L., Liu, C., Oliva, A., & Fernandez-Ruiz, A. (2023) · Neuron · doi:10.1016/j.neuron.2023.04.015 · Cited by 101 · see citing works
Savelli, F., & Knierim, J. J. (2019) · Journal of Experimental Biology · doi:10.1242/jeb.188912 · Cited by 93 · see citing works
Vinepinsky, E., Cohen, L., Perchik, S., Ben-Shahar, O., Donchin, O., & Segev, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-71217-1 · Cited by 87 · see citing works
Neurophysiology of Remembering
Buzsáki, G., McKenzie, S., & Davachi, L. (2022) · Annual Review of Psychology · doi:10.1146/annurev-psych-021721-110002 · Cited by 84 · see citing works
Self-citationBonasia, K., Blommesteyn, J., & Moscovitch, M. (2016) · Hippocampus · doi:10.1002/hipo.22539 · Cited by 84 · see citing works
Control of locomotor speed, arousal, and hippocampal theta rhythms by the nucleus incertus
Lu, L., Ren, Y., Yu, T., Liu, Z., Wang, S., Tan, L., Zeng, J., Feng, Q., Lin, R., Liu, Y., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-14116-y · Cited by 84 · see citing works
Environmental deformations dynamically shift the grid cell spatial metric
Keinath, A. T., Epstein, R. A., & Balasubramanian, V. (2018) · eLife · doi:10.7554/elife.38169 · Cited by 67 · see citing works
Hippocampal network oscillations at the interplay between innate anxiety and learned fear
Çalışkan, G., & Stork, O. (2019) · Psychopharmacology · doi:10.1007/s00213-018-5109-z · Cited by 72 · see citing works
Ma, T. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15541 · Cited by 55 · see citing works
Generating meaning: active inference and the scope and limits of passive AI
Pezzulo, G., Parr, T., Cisek, P., Clark, A., & Friston, K. (2024) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.10.002 · Cited by 80 · see citing works
Bosch, C., Masachs, N., Exposito-Alonso, D., Martínez, A., Teixeira, C. M., Fernaud, I., Pujadas, L., Ulloa, F., Comella, J. X., DeFelipe, J., et al. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw216 · Cited by 70 · see citing works
Linking hippocampal multiplexed tuning, Hebbian plasticity and navigation
Moore, J. J., Cushman, J. D., Acharya, L., Popeney, B., & Mehta, M. R. (2021) · Nature · doi:10.1038/s41586-021-03989-z · Cited by 69 · see citing works
Linking Social Cognition to Learning and Memory
Leblanc, H., & Ramirez, S. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.1280-20.2020 · Cited by 69 · see citing works
Saxena, K., Singh, P., Sahoo, P., Sahu, S., Ghosh, S., Ray, K., Fujita, D., & Bandyopadhyay, A. (2020) · Fractal and Fractional · doi:10.3390/fractalfract4020011 · Cited by 71 · see citing works
Cell types for our sense of location: where we are and where we are going
Hardcastle, K., Ganguli, S., & Giocomo, L. M. (2017) · Nature Neuroscience · doi:10.1038/nn.4654 · Cited by 59 · see citing works
Spatial Cognition in Teleost Fish: Strategies and Mechanisms
Rodríguez, F., Quintero, B., Amores, L., Madrid, D., Salas-Peña, C., & Salas, C. (2021) · Animals · doi:10.3390/ani11082271 · Cited by 59 · see citing works
Mental navigation and the neural mechanisms of insight
Aru, J., Drüke, M., Pikamäe, J., & Larkum, M. E. (2023) · Trends in Neurosciences · doi:10.1016/j.tins.2022.11.002 · Cited by 38 · see citing works
Zhang, H., Chen, Z., Zhong, Z., Gong, W., & Li, J. (2018) · Brain and Behavior · doi:10.1002/brb3.1127 · Cited by 37 · see citing works
Baseline brain activity predicts response to neuromodulatory pain treatment
Jensen, M. P., Sherlin, L. H., Fregni, F., Gianas, A., Howe, J. D., & Hakimian, S. (2014) · Pain Medicine · doi:10.1111/pme.12546 · Cited by 35 · see citing works
Stoiljkovic, M., Leventhal, L., Chen, A., Chen, T., Driscoll, R., Flood, D., Hodgdon, H., Hurst, R., Nagy, D., Piser, T., et al. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.006 · Cited by 29 · see citing works
The mnemonic functions of episodic memory
Boyle, A. (2022) · Philosophical Psychology · doi:10.1080/09515089.2021.1980520 · Cited by 27 · see citing works
Lu, H.-C., Pollack, H., Lefante, J. J., Mills, A. A., & Tian, D. (2019) · Sleep · doi:10.1093/sleep/zsy253 · Cited by 22 · see citing works
Differential Impact of Acute and Chronic Stress on CA1 Spatial Coding and Gamma Oscillations
Tomar, A., Polygalov, D., & McHugh, T. J. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.710725 · Cited by 21 · see citing works
Farkhondeh Tale Navi, F., Heysieattalab, S., Ramanathan, D. S., Raoufy, M. R., & Nazari, M. A. (2022) · Neuroscience · doi:10.1016/j.neuroscience.2021.12.004 · Cited by 19 · see citing works
Dunn, S. L. S., Town, S. M., Bizley, J. K., & Bendor, D. (2022) · Nature Communications · doi:10.1038/s41467-022-33507-2 · Cited by 17 · see citing works
Linking neuronal structure to function in rodent hippocampus: a methodological prospective
Preston-Ferrer, P., & Burgalossi, A. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2732-7 · Cited by 11 · see citing works
Generating Meaning: Active Inference and the Scope and Limits of Passive AI
Pezzulo, G., Parr, T., Cisek, P., Clark, A., & Friston, K. (2023) · doi:10.31234/osf.io/8xgzv · Cited by 8 · see citing works
Enhancing spatial navigation performance through boundary cues in the virtual environment
Wang, J., Li, Y., Li, Y., Hu, X., & Song, X. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.105283 · Cited by 2 · see citing works
Long-term Memory Reorganization of Navigational Episodes
Iggena, D., Schmelter, T., Maier, P. M., Reguieg, K., Finke, C., Hildebrand, K., & Ploner, C. J. (2026) · Nature Human Behaviour · doi:10.1038/s41562-026-02472-x
“This information includes the paths we travel, the landmarks we encounter and the spatial relationships between these landmarks and ourselves 1–4 .”
Place and behavioral modulation of hippocampal neurons during immobility
Sartorato, N., Zouridis, I. S., Narantsatsralt, U.-U., Blanco-Hernández, E., & Burgalossi, A. (2026) · Nature Communications · doi:10.1038/s41467-026-75492-w · Cited by 1 · see citing works
“Theta oscillations — although not necessary for the emergence of the place code 21,22 — play a major role in organizing place cellactivityintotemporalsequencesthatmaptheavailablespace(and, similarly, episodic events 4,23,24 ).”
- Authors
- Buzsáki, G., & Moser, E. I.
- Affiliations
- New York University (US)
- Norwegian University of Science and Technology (NO)
- Corresponding author
- Buzsáki, György
- Venue
- Nature Neuroscience
- Published
- 2013-01-28
- Volume
- 16
- Issue
- 2
- Pages
- 130-138
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC4079500
- OpenAlex
- W2072843066
- Cited by
- 1,847
- References
- 102
- Citations by year
- 2026: 126 · 2025: 159 · 2024: 174 · 2023: 176 · 2022: 175 · 2021: 152 · 2020: 137 · 2019: 141 · 2018: 142 · 2017: 114 · 2016: 120 · 2015: 97 · 2014: 80 · 2013: 48 · 2012: 1
- FWCI
- 9.86
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH054671, MH54671)
- National Institute of Neurological Disorders and Stroke (NS074015, R01NS034994, R01NS074015, NS-34994)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Physical Sciences › Engineering › Automotive Engineering › Spatial Cognition and Navigation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- hippocampus, entorhinal cortex, spatial memory, spatial navigation, theta oscillations, planning, hippocampal oscillations
- MeSH terms
- Animals, Hippocampus, Humans, Memory, Models, Neurological, Neural Pathways, Neurons, Space Perception, Spatial Behavior, Theta Rhythm, Entorhinal Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
