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N6-methyladenosine marks primary microRNAs for processing

Alarcón, Claudio R., Lee, Hyeseung, Goodarzi, Hani, Halberg, Nils, Tavazoie, Sohail F.·2015·Nature

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Research works printed but not linked: 22

  1. Gregory, R. I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235–240 (2004) · DOI
  2. Han, J. et al. The Drosha–DGCR8 complex in primary microRNA processing. Genes Dev. 18, 3016–3027 (2004) · DOI
  3. Landthaler, M., Yalcin, A. & Tuschl, T. The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14, 2162–2167 (2004) · DOI
  4. Han, J. et al. Molecular basis for the recognition of primary microRNAs by the Drosha–DGCR8 complex. Cell 125, 887–901 (2006) · DOI
  5. Elemento, O., Slonim, N. & Tavazoie, S. A universal framework for regulatory element discovery across all genomes and data types. Mol. Cell 28, 337–350 (2007) · DOI
  6. Wei, C. M. & Moss, B. Nucleotide sequences at the N6-methyladenosine sites of HeLa cell messenger ribonucleic acid. Biochemistry 16, 1672–1676 (1977) · DOI
  7. Dominissini, D. et al. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature 485, 201–206 (2012) · DOI · Paper page
  8. Bokar, J. A., Shambaugh, M. E., Polayes, D., Matera, A. G. & Rottman, F. M. Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase. RNA 3, 1233–1247 (1997)
  9. Sibbritt, T., Patel, H. R. & Preiss, T. Mapping and significance of the mRNA methylome. RNA 4, 397–422 (2013)
  10. Camper, S. A., Albers, R. J., Coward, J. K. & Rottman, F. M. Effect of undermethylation on mRNA cytoplasmic appearance and half-life. Mol. Cell. Biol. 4, 538–543 (1984) · DOI · Paper page
  11. Carroll, S. M., Narayan, P. & Rottman, F. M. N6-methyladenosine residues in an intron-specific region of prolactin pre-mRNA. Mol. Cell. Biol. 10, 4456–4465 (1990) · DOI
  12. Thorvaldsdóttir, H., Robinson, J. T. & Mesirov, J. P. Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief. Bioinform. 14, 178–192 (2013) · DOI · Paper page
  13. Bujnicki, J. M., Feder, M., Radlinska, M. & Blumenthal, R. M. Structure prediction and phylogenetic analysis of a functionally diverse family of proteins homologous to the MT-A70 subunit of the human mRNA:m6A methyltransferase. J. Mol. Evol. 55, 431–444 (2002) · DOI
  14. Chi, S. W., Zang, J. B., Mele, A. & Darnell, R. B. Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps. Nature 460, 479–486 (2009) · DOI · Paper page
  15. Pollard, K. S., Hubisz, M. J., Rosenbloom, K. R. & Siepel, A. Detection of nonneutral substitution rates on mammalian phylogenies. Genome Res. 20, 110–121 (2010) · DOI · Paper page
  16. Lee, Y. & Kim, V. N. In vitro and In vivo assays for the activity of Drosha complex. Methods Enzymol. 427, 87–106 (2007) · DOI
  17. Auyeung, V. C., Ulitsky, I., McGeary, S. E. & Bartel, D. P. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell 152, 844–858 (2013) · DOI · Paper page
  18. Tavazoie, S. F. et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451, 147–152 (2008) · DOI
  19. Giannopoulou, E. G. & Elemento, O. An integrated ChIP-seq analysis platform with customizable workflows. BMC Bioinformatics 12, 277 (2011) · DOI
  20. Zhang, C. & Darnell, R. B. Mapping in vivo protein–RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nature Biotechnol. 29, 607–614 (2011) · DOI
  21. Kim, S. W. et al. A sensitive non-radioactive northern blot method to detect small RNAs. Nucleic Acids Res. 38, e98 (2010) · DOI
  22. Batista, P. J. et al. m6A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell 15, 707–719 (2014) · DOI · Paper page

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Metadata

Authors
Alarcón, C. R., Lee, H., Goodarzi, H., Halberg, N., & Tavazoie, S. F.
Venue
Nature
Published
2015-03
Volume
519
Issue
7544
Pages
482-485
ISSN
  • 0028-0836
  • 1476-4687
Cited by
1,315
References
4
Language
en

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CoChat. (2026). Citation check: N6-methyladenosine marks primary microRNAs for processing. https://app.cochat.ai/papers/10.1038/nature14281
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Alarcón, C. R., Lee, H., Goodarzi, H., Halberg, N., & Tavazoie, S. F. (2015). N6-methyladenosine marks primary microRNAs for processing. Nature. https://doi.org/10.1038/nature14281

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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