The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
The gene cortex controls mimicry and crypsis in butterflies and moths
Open accessAbstract
Abstract A major challenge in evolutionary biology is to understand the origins of novel structures. The wing patterns of butterflies and moths are derived phenotypes unique to the Lepidoptera. Here we identify a gene that we name poikilomousa ( poik ), which regulates colour pattern switches in the mimetic Heliconius butterflies. Strong associations between phenotypic variation and DNA sequence variation are seen in three different Heliconius species, in addition to associations between gene expression and colour pattern. Colour pattern variants are also associated with differences in splicing of poik transcripts. poik is a member of the conserved fizzy family of cell cycle regulators. It belongs to a faster evolving subfamily, the closest functionally characterised orthologue being the cortex gene in Drosophila, a female germ-line specific protein involved in meiosis. poik appears to have adopted a novel function in the Lepidoptera and become a major target for natural selection acting on colour and pattern variation in this group.
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Cited by
Repeatable phenotypic but not genetic response to selection on body size in the black soldier fly
Generalovic, T. N., Zhou, W., Zhao, L. C., Leonard, S., Warren, I. A., Pipan, M., & Jiggins, C. D. (2025) · doi:10.1101/2025.02.25.640052 · Cited by 6
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Metadata
- Authors
- Nadeau, N. J., Pardo-Diaz, C., Whibley, A., Supple, M. A., Saenko, S. V., Wallbank, R. W. R., Wu, G. C., Maroja, L., Ferguson, L., Hanly, J. J., Hines, H., Salazar, C., Merrill, R. M., Dowling, A. J., ffrench-Constant, R. H., Llaurens, V., Joron, M., McMillan, W. O., & Jiggins, C. D.
- Venue
- Nature
- Published
- 2016-06-01
- Volume
- 534
- Issue
- 7605
- Pages
- 106-110
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2413031428
- Cited by
- 264
- References
- 72
- FWCI
- 21.04
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Nadeau, N. J., Pardo-Diaz, C., Whibley, A., Supple, M. A., Saenko, S. V., Wallbank, R. W. R., Wu, G. C., Maroja, L., Ferguson, L., Hanly, J. J., Hines, H., Salazar, C., Merrill, R. M., Dowling, A. J., ffrench-Constant, R. H., Llaurens, V., Joron, M., McMillan, W. O., & Jiggins, C. D. (2016). The gene cortex controls mimicry and crypsis in butterflies and moths. Nature. https://doi.org/10.1038/nature17961
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
