The DOI matches its Crossref record; 98 of the 99 references it cites were found in a registry or an index.
Ageing, neurodegeneration and brain rejuvenation
Open accessAbstract
Although systemic diseases take the biggest toll on human health and well-being, increasingly, a failing brain is the arbiter of a death preceded by a gradual loss of the essence of being. Ageing, which is fundamental to neurodegeneration and dementia, affects every organ in the body and seems to be encoded partly in a blood-based signature. Indeed, factors in the circulation have been shown to modulate ageing and to rejuvenate numerous organs, including the brain. The discovery of such factors, the identification of their origins and a deeper understanding of their functions is ushering in a new era in ageing and dementia research.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Aging leads to dramatic changes in cognitive and neuronal function, the decline of which contributes to the development of neurological disorders1.”
From MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity (2025) · cites this paper as [1]
Experimental — accuracy not yet measuredIn the citing paper
“The removal of circulating pro-ageing factors also holds the potential to revitalize the brain in animal studies.391”
From Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances (2025) · cites this paper as [391]
In the citing paper
“Furthermore, the ability of interventions not only to slow the rate of aging but actually to rejuvenate cells and tissues seemingly by reversing aging processes expands the spectrum of healthspan-promoting treatments.79,80,81,82,83”
From Asynchronous, contagious and digital aging (2021) · cites this paper as [81]
In the citing paper
“Given that cell non-autonomous changes are also known to regulate aging-dependent changes 2,3 , we also detail ligand-receptor interactions among nearly all the cell types in the brain that are modified by aging.”
From Single-cell transcriptomic profiling of the aging mouse brain (2019) · cites this paper as [2]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,526
DNA methylation age of human tissues and cell types
Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075
Neuroinflammation in Alzheimer's disease
Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226
Self-citationMeta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease
(EADI), E. A. D. I., Lambert, J.-C., (GERAD), G. A. E. R. I. A. D., Alzheimer's Disease Genetic Consortium (ADGC), (CHARGE), C. F. H. A. A. R. I. G. E., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., et al. (2013) · Nature Genetics · doi:10.1038/ng.2802 · Cited by 4,336
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Franceschi, C., & Campisi, J. (2014) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glu057 · Cited by 3,891
TREM2 Variants in Alzheimer's Disease
Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Jonsson, T., Stefansson, H., Steinberg, S., Jonsdottir, I., Jonsson, P. V., Snaedal, J., Bjornsson, S., Huttenlocher, J., Levey, A. I., Lah, J. J., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211103 · Cited by 2,558
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature · doi:10.1038/nature03260 · Cited by 2,287
Initiative, T. A. D. N., Hollingworth, P., CHARGE consortium, EADI1 consortium, Harold, D., Sims, R., Gerrish, A., Lambert, J.-C., Carrasquillo, M. M., Abraham, R., et al. (2011) · Nature Genetics · doi:10.1038/ng.803 · Cited by 1,997
Cited by
Sorted by citations
Items 801–900 of 1,000
Vázquez‐Roque, R. A., Pacheco‐Flores, M., Penagos-Corzo, J. C., Flores, G., Aguilera, J., Treviño, S., Guevara, J., Díaz, A., & Venegas, B. (2020) · Synapse · doi:10.1002/syn.22193 · Cited by 4
Ishola, I. O., Afolayan, O., Odutola, I. O., Faniyan, O., & Adeyemi, O. O. (2021) · Nigerian Journal of Physiological Sciences · Cited by 4
Gezici, S., & Koçum, D. (2021) · Türk doğa ve fen dergisi :/Türk doğa ve fen dergisi · doi:10.46810/tdfd.977356 · Cited by 4
Ge, M., Jiang, J., Yang, L., Yang, X., He, Y., Li, G., & Kong, Q. (2022) · Genes · doi:10.3390/genes13050749 · Cited by 4
Chen, M., Zhu, Y., Li, H., Zhang, Y., & Han, M. (2022) · Brain Sciences · doi:10.3390/brainsci12060690 · Cited by 4
Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy
Fernández‐Albarral, J. A., Salobrar‐García, E., Matamoros, J. A., Fernández‐Mendívil, C., del Sastre, E., Chen, L., de Hoz, R., López‐Cuenca, I., Sánchez-Puebla, L., Ramirez, J. M., et al. (2022) · Antioxidants · doi:10.3390/antiox11112151 · Cited by 4
CRISPR: a tool with potential for genomic reprogramming in neurological disorders
Dhuriya, Y. K., & Naik, A. A. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-08136-z · Cited by 4
Papadimitriou, C., Coşacak, M. İ., Mashkaryan, V., Çelikkaya, H., Bray, L. J., Bhattarai, P., Hollak, H., Chen, X., He, S., Antos, C. L., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/225243 · Cited by 4
Identification of biological processes and potential inhibitors for aging skinPreprint
Wang, J., & Gu, H. (2021) · Research Square · doi:10.21203/rs.3.rs-1104916/v1 · Cited by 4
Umeda, T., Sakai, A., Uekado, R., Shigemori, K., Nakajima, R., Yamana, K., & Tomiyama, T. (2024) · eLife · doi:10.7554/elife.100737.2 · Cited by 5
Jofré‐Saldía, E., Ojeda, Á. H., Arriagada-Molina, J., Villalobos-Gorigoitía, Á., Valladares-Ide, D., & Bravo, M. (2024) · International Journal of Morphology · doi:10.4067/s0717-95022024000200437 · Cited by 3
Min, W. Z., & Tang, Z. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2024.112503 · Cited by 3
Parallel Gene Expression Changes in Ventral Midbrain Dopamine and GABA Neurons during Normal Aging
Drumond‐Bock, A. L., Blankenship, H. E., Pham, K. D., Carter, K. A., Freeman, W. M., & Beckstead, M. J. (2025) · eNeuro · doi:10.1523/eneuro.0107-25.2025 · Cited by 3
Tau seeding activity in Alzheimer's disease: Characteristics, factors, and applications
Liu, Y., Chen, Y., Chen, Z., Wan, H., & Wu, C. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251378772 · Cited by 4
Biological aging and gout risk in hyperuricemia: a UK Biobank cohort study
Li, N., Chen, Z., Han, M., Shang, A., Zhou, J., Sun, Y. X., Li, Y., Sun, J., Shen, A., Yang, Y., et al. (2025) · International Journal of Surgery · doi:10.1097/js9.0000000000003948 · Cited by 3
ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration
Pourshafie, N., Alexander, D. C., Xu, H. W., Yang, K., Donahue, G., Lei, X., Zhang, S., Shcherbakova, O., Hogan, C., Gilbert, M., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2503834122 · Cited by 4
Immune Aging as a Failure of Programmed Cell Death Coordination
Lee, H.-M., Kim, E.-J., Hasan, A., & Kang, T. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27031554 · Cited by 3
Ding, M., Chen, B., Xiao, J., Rong, J., Feng, Y., Gao, C., Du, D., Tu, Y., & Peng, F. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2520119123 · Cited by 3
Ma, J., Yang, B., Jiang, X., Wang, L., Wei, W., Cao, Y., & Li, H. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113177 · Cited by 4
Rejili, M., Al‐kuraishy, H. M., Shokr, M. M., & Batiha, G. E. (2026) · Biogerontology · doi:10.1007/s10522-026-10457-6 · Cited by 3
Free ubiquitin: a novel therapeutic target for neurodegenerative diseases
Park, C.-W., & Ryu, K. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.306075 · Cited by 3
The neural economics of brain aging
Kosyakovsky, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-91621-5 · Cited by 3
Zhao, Y., Xu, J., Feng, Z., & Wang, J. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2021.721427 · Cited by 3
Fast and functionally specific cortical thickness changes induced by visual stimulation
Zaretskaya, N., Fink, E., Arsenovic, A., & Ischebeck, A. K. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac244 · Cited by 4
Aronia melanocarpa:A Review of Potential Antioxidants on Neuroprotection and Cognitive Performance
Sultana, R. (2021) · doi:10.52816/jdvat.2021.1301 · Cited by 3
Anti-aging strategies, plant bioactives, and drug development: current insights
Sripanidkulchai, B., Suttajit, M., & Ratanavalachai, T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90581-7.00013-x · Cited by 3
Innate immunity in brain aging and neurodegeneration
Pai, S. K. (2024) · Aging Brain · doi:10.1016/j.nbas.2024.100108 · Cited by 3
Blood-based therapies to combat neurodegenerative diseases
Jy, L., Lim, M. C. X., Koh, R. Y., Tsen, M. T., & Chye, S. M. (2024) · Metabolic Brain Disease · doi:10.1007/s11011-024-01368-x · Cited by 3
Yan, Y., Hu, M., He, X., Xu, Y., Sun, X., Peng, J., Zhao, F., & Shao, Y. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121040 · Cited by 3
Machado, H., Machado, J. P., Alves, C., Soares, C. M. D., Grosso, C., Rodrigues, J. M., & Criado, M. B. (2025) · Nutraceuticals · doi:10.3390/nutraceuticals5030020 · Cited by 3
Fazio, C. D., & Palermo, S. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.114842 · Cited by 5
Aneuploidy is Linked to Neurological Phenotypes Through Oxidative Stress
Islam, A., Shaukat, Z., Hussain, R., Ricos, M. G., Dibbens, L. M., & Gregory, S. L. (2024) · Journal of Molecular Neuroscience · doi:10.1007/s12031-024-02227-1 · Cited by 3
Juber, N. F., Hofbauer, L. M., & Rodriguez, F. S. (2024) · Journal of Asthma · doi:10.1080/02770903.2024.2361785 · Cited by 3
Zou, C., Cai, R., Li, Y., Yu, X., Zhang, G., Alitongbieke, G., Pan, Y., & Zhang, S. Q. (2024) · iScience · doi:10.1016/j.isci.2024.110766 · Cited by 3
Yang, Y., Lu, S., Xu, Q., Yu, J. Z., Wang, Z., Zhang, B.-S., & Hong, K. (2024) · World Journal of Psychiatry · doi:10.5498/wjp.v14.i12.1925 · Cited by 3
Human DDIT4L intron retention contributes to cognitive impairment and amyloid plaque formation
Li, K., Shi, H., Li, Z., You, P., Pan, J., Cai, Y.-C., Li, J.-W., Ma, X.-F., Zhang, S., Diao, L., et al. (2025) · Cell Discovery · doi:10.1038/s41421-024-00759-9 · Cited by 3
Revisiting the advance of age-dependent α-synuclein propagation and aggregation
Song, D., & Li, J. (2025) · Ageing and Neurodegenerative Diseases · doi:10.20517/and.2024.44 · Cited by 4
Voronina, N. A., Kucheryanu, V. G., Капица, И. Г., & Воронина, Т. А. (2019) · Nauchno-prakticheskii zhurnal «Patogenez» · doi:10.25557/2310-0435.2019.04.57-62 · Cited by 3
Patil, S. B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822522-6.00012-6 · Cited by 3
Review on various factors responsible for neurodegenerative disorders
Tembhurnikar, H. J., Thool, N. D., Patil, R. J., & Das, R. K. (2021) · GSC Biological and Pharmaceutical Sciences · doi:10.30574/gscbps.2021.16.1.0203 · Cited by 3
Minghinelli, F. E., Devoto, P. R., Anzorena, A. M. S., Carvallo, L. J., Baldoncini, M., Bonilla, G., & Recalde, R. J. (2022) · World Neurosurgery · doi:10.1016/j.wneu.2022.01.090 · Cited by 3
Guzzo, S., BONIS, P. D., Pavan, B., & Fadiga, L. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.346054 · Cited by 3
Li, Z., Cai, K., Sun, Y., Zhou, D., Yan, J., Luo, S., Huang, G., Gao, Y., & Li, W. (2023) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2022-0111 · Cited by 3
Ibrahim, J., Aitken, G., & Ranson, D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781316823040.003 · Cited by 3
Microbiota: Current Research and Emerging Trends
Salazar, N., González Solares, S., Nogacka, A., Rios-Covián, D., Arboleya, S., Fernández, M. G., & González de los Reyes-Gavilán, C. (2018) · Caister Academic Press eBooks · doi:10.21775/9781910190937 · Cited by 3
Pribut, H. J., Vázquez, D., Wei, A. D., Tennyson, S. S., Davis, I. R., Roesch, M. R., & Li, X. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0916-21.2021 · Cited by 4
Deciphering Adult Neural Stem Cells with Single-Cell Sequencing
Liu, Y., Zhu, Y., Shi, Y., Liu, X., Su, W., & Zhuo, Y. (2023) · Stem Cells and Development · doi:10.1089/scd.2022.0234 · Cited by 3
Zolezzi, J. M., Candia, S. B., & Inestrosa, N. C. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.86167 · Cited by 3
Role of Antioxidant Nutraceuticals in Neurodegenerative Diseases
Rajadurai, M., Paramasivam, A., & Chandrashekar, L. A. (2022) · Nutritional neurosciences · doi:10.1007/978-981-16-8158-5_15 · Cited by 3
Kaur, G., Poljak, A., & Sachdev, P. S. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.30.478370 · Cited by 3
Canevelli, M., & Marsili, L. (2022) · Wiley eBooks · doi:10.1002/9781119484288.ch6 · Cited by 3
Advanced Polymeric Nanoparticles for the Treatment of Neurodegenerative Diseases
Ferrão, R., & Rai, A. (2024) · Wiley eBooks · doi:10.1002/9783527837021.ch27 · Cited by 3
Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders
Sarkar, P., Kumar, A. A., Behera, P. S., & Thirumurugan, K. (2023) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2023.02.013 · Cited by 2
Ayurveda: Ayurvedic herbs against neurological disorders: are they golden nuggets?
Muralidhara, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-19084-1.00022-3 · Cited by 2
Ghanbari, A., Rad, F., Shahraki, M. H., Hosseini, E., Barmak, M. J., & Zibara, K. (2024) · Neuroscience Letters · doi:10.1016/j.neulet.2024.137951 · Cited by 2
Yu, K., Yang, S., Song, H., Sun, Z., Wang, K., Zhu, Y., Yang, C., Hao, R., & Cao, Y. (2025) · Biosensors · doi:10.3390/bios15040242 · Cited by 2
Lo, J. S.-I., Wang, J., Tran, D., Nemeh, G., Liu, B., Shin, S. H., Athertya, J., Schiehser, D. M., Ma, Y., & Du, J. (2025) · NeuroImage Clinical · doi:10.1016/j.nicl.2025.103801 · Cited by 2
Oat Bran Hydrolysates Alleviate Oxidative Stress and Inflammation in d ‐Galactose‐Induced Aging Mice
Ma, H., Wang, R., Sun, M., Ma, S., & Zhang, M. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70433 · Cited by 2
Liao, Y., Xu, F., Yan, Y., Zhou, S., Liu, N., Dou, B., Srinivasan, N., Wang, W., Zhu, X., Ye, J., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1455994 · Cited by 2
Tian, S. L., Ye, T., Tian, C., Zhang, Y., He, L., Shen, H., Xu, Y., & Cheng, X. (2025) · Immunity & Ageing · doi:10.1186/s12979-025-00528-6 · Cited by 2
Huang, S., Zhou, Y., Liu, J., Sun, S., Zhang, T., Ma, L., Liu, S., Deng, D., Shu, S., Wang, Y., et al. (2025) · Perioperative Medicine · doi:10.1186/s13741-025-00565-1 · Cited by 2
Rodríguez‐Fernández, B., González‐Escalante, A., Genius, P., Evans, T. E., Ortiz-Romero, P. L., Minguillón, C., Kollmorgen, G., Ashton, N. J., Zetterberg, H., Blennow, K., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105886 · Cited by 2
Integration of Genetic Information to Improve Brain Age Gap Estimation Models in the UK Biobank
Mohite, A., Ardila, K., Charatpangoon, P., Munro, E., Zhang, Q., Long, Q., Curtis, C. F., & MacDonald, M. E. (2025) · Human Brain Mapping · doi:10.1002/hbm.70331 · Cited by 2
Qansuwa, E. M., Atalah, H. N., & Salama, M. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.09.050 · Cited by 2
Shamsi, A., Alrouji, M., AlOmeir, O., Tasqeruddin, S., Khuzin, D., & Zuberi, A. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1681891 · Cited by 2
Träuble, J., Hiscox, L. V., Johnson, C. L., Avilés-Rivero, A. I., Schönlieb, C., & Schierle, G. S. K. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2025.105996 · Cited by 2
Biscetti, L., Gambuzza, M. E., Princiotto, M., Sabbatinelli, J., Olivieri, F., Fiorillo, M., Chinigò, C., Muglia, L., Cozza, A., Beccacece, A., et al. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119326 · Cited by 2
Assessing the potential molecular mechanism of arsenite-induced skin cell senescence
Du, S., Yang, F., Wu, L., Hu, D., Zhang, Y., Gong, M., Yang, Y., Yang, X., & Zeng, Q. (2023) · Toxicology Research · doi:10.1093/toxres/tfad075 · Cited by 2
Wibawa, T. H. A., Rattyananda, B. S., Setiadi, Y., Widyasari, E. M., Sriyani, M. E., Wongso, H., Febrian, . B., Mahendra, I., Kurniawan, A., Halimah, I., et al. (2024) · E3S Web of Conferences · doi:10.1051/e3sconf/202450303001 · Cited by 2
Envejecimiento humano: un análisis integral desde la perspectiva de la medicina interna
Alvear, M. E. C., Plaza, G. R. R., Tobar, J. C. Y., & Avilés, M. E. I. (2024) · RECIAMUC · doi:10.26820/reciamuc/8.(1).ene.2024.297-319 · Cited by 3
Zhao, R., Yuan, H., Chen, S., Xu, K., Zhang, T., Liu, Z., Jiang, Y., Suo, C., & Chen, X. (2024) · International Journal of Cancer · doi:10.1002/ijc.35161 · Cited by 2
Guo, H., Liu, Y., Yang, R., Li, X., Teng, Y., Wei, W., & Zhang, D. (2025) · BMC Public Health · doi:10.1186/s12889-025-24534-x · Cited by 2
Reproductive Hormones and Dementia
Naftolin, F. N., Silva, I., & Orley, A. (2018) · Reproductive medicine for clinicians · doi:10.1007/978-3-319-78009-2_16 · Cited by 2
Circulating Biomarkers of Aging
Zhang, H., Wang, B. Z., & Jin, K. (2019) · Healthy ageing and longevity · doi:10.1007/978-3-030-24970-0_21 · Cited by 2
Targeting Mitochondria and Redox Dyshomeostasis in Brain Ageing: An Update
Cardoso, S., & Moreira, P. I. (2021) · Healthy ageing and longevity · doi:10.1007/978-3-030-84965-8_8 · Cited by 2
Tundis, R., Acquaviva, R., Bonesi, M., Malfa, G. A., Tomasello, B., & Loizzo, M. R. (2019) · Springer eBooks · doi:10.1007/978-981-13-1745-3_9-1 · Cited by 2
Premorbid factors of early post-stroke cognitive impairment
Grishina, A. А., Tynterova, A. M., & Skalin, Y. E. (2022) · V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY · doi:10.31363/2313-7053-2022-56-3-48-56 · Cited by 2
Ma’arif, B., Tamara, Y., Al-Azzam, F. A. S., Azzahara, R., Rizki, F., Sugihantoro, H., Maulina, N., & Agil, M. (2023) · RASAYAN Journal of Chemistry · doi:10.31788/rjc.2023.1628342 · Cited by 2
Saini, S., Medda, N., Pramanik, S. D., Pathak, T., & Roy, P. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-19084-1.00005-3 · Cited by 2
Aziz, N., Vinod, Y. R., Sarkar, D., Wal, A., Verma, V., & Wal, P. (2023) · Current Traditional Medicine · doi:10.2174/2215083810666230912150053 · Cited by 2
Sinvani, L., & Mendelson, D. A. (2024) · Springer eBooks · doi:10.1007/978-3-030-74720-6_15 · Cited by 2
Ojeda, Á. H., Jofré‐Saldía, E., Barahona-Fuentes, G. D. F., Yeomans‐Cabrera, M., & Bravo, M. (2024) · Health Science Reports · doi:10.1002/hsr2.1890 · Cited by 2
Olfactory Function as a Potential Predictor of Cognitive Impairment in Men and Women
Masala, C., Loy, F., Pinna, I., Manis, N. A., Ercoli, T., & Solla, P. (2024) · Biology · doi:10.3390/biology13070503 · Cited by 2
Khalili, R., Kehayia, E., & Roig, M. (2024) · Canadian Geriatrics Journal · doi:10.5770/cgj.27.707 · Cited by 2
Effects of Formaldehyde on Protein (Tau) Aggregation and Cytotoxicity
He, R. (2017) · Springer eBooks · doi:10.1007/978-94-024-1177-5_7 · Cited by 2
A quantitative proteomics analysis for small molecule Stemazole’s effect on human neural stem cells
Li, H., Zhang, Y., Zhang, J., Zhao, C., Zhu, Y., & Han, M. (2020) · Proteome Science · doi:10.1186/s12953-020-00168-2 · Cited by 2
Chochkova, M. G., Rusew, R., Kalfin, R. E., Tancheva, L. P., Lazarova, M. I., Sbirkova-Dimitrova, H. I., Popatanasov, А., Tasheva, K. N., Shivachev, B. L., Petek, N., et al. (2022) · Crystals · doi:10.3390/cryst12111518 · Cited by 2
PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders
Shang, D., Lan, T., Wang, Y., Li, X., Liu, Q., Dong, H., Xu, B., Cheng, H., & Zhou, R. (2022) · Cell & Bioscience · doi:10.1186/s13578-022-00925-0 · Cited by 2
Oxides, oxidative stress, and cellular aging
Yadav, S., Deepika, & Maurya, P. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90538-1.00007-8 · Cited by 2
Regenerative nanomedicine applications for neurodegenerative diseases of central nervous system
Alkhalifa, H., Alshebber, E., & Taurin, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820466-5.00012-0 · Cited by 2
Bourbakis, N. G., Michalopoulos, K., Antonakakis, M., & Zervakis, M. (2022) · International Journal of Neural Systems · doi:10.1142/s012906572250006x · Cited by 2
Neurodegenerative Diseases and the Gut Microbiota
Cabré, S., O’Riordan, K. J., & Cryan, J. F. (2022) · Progress in inflammation research · doi:10.1007/978-3-030-91051-8_11 · Cited by 2
Gao-Zi-Yao improves learning and memory function in old spontaneous hypertensive rats
Han, M., Jiang, W.-Y., Jiang, Y., Wang, L., Xue, R., Zhang, G., & Chen, J. (2022) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-022-03630-0 · Cited by 2
Chen, C., Chen, P., Tung, Y.-H., Hsu, Y., & Tseng, W. I. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.23.309369 · Cited by 2
The caloric restriction fallacy, rodent diet aids and the tumor suppression theory of agingPreprint
Wolf, A. M. (2021) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/a2689 · Cited by 2
Bernard, M., Shine, J. P., Bičanski, A., & Wolbers, T. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.11.24.690256 · Cited by 2
Polyphenols and Neuroprotection: The Role of Adenosine Receptors
Sánchez-Melgar, A., Albasanz, J. L., & Martı́n, M. (2019) · Journal of Caffeine and Adenosine Research · doi:10.1089/caff.2019.0007 · Cited by 1
Romera, C., Riba, M., Alsina, R., Sartorio, M., Vilaplana, J., Pelegrı́, C., & del Valle, J. (2024) · Immunity & Ageing · doi:10.1186/s12979-024-00460-1 · Cited by 1
Nutraceuticals as an Intervention for Healthy Brain Ageing
Sah, P., Tomtheelnganbee, E., Syiem, D., & Sharma, R. (2024) · Healthy ageing and longevity · doi:10.1007/978-3-031-68513-2_13 · Cited by 1
Ozawa, M. Y., Saito, R., Konno, T., Kuroha, Y., Ikeda, T., Yokoseki, A., Tani, T., Sato, T., Idezuka, J., Koide, R., et al. (2025) · Brain Pathology · doi:10.1111/bpa.70016 · Cited by 1
Metadata
- Authors
- Wyss-Coray, T.
- Venue
- Nature
- Published
- 2016-11
- Volume
- 539
- Issue
- 7628
- Pages
- 180-186
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC5172605
- OpenAlex
- W2549552700
- Cited by
- 1,147
- References
- 99
- Citations by year
- 2026: 88 · 2025: 127 · 2024: 133 · 2023: 156 · 2022: 162 · 2021: 143 · 2020: 122 · 2019: 91 · 2018: 79 · 2017: 44
- FWCI
- 10.25
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- National Institute on Aging (P50AG047366, R01AG045034)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- brain aging, neurodegeneration, dementia, brain rejuvenation, circulating factors, blood-based biomarkers
- MeSH terms
- Aging, Animals, Brain, Cell Communication, Humans, Inflammation, Rejuvenation, Neurodegenerative Diseases, Proteome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
