Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

The central role of the propensity score in observational studies for causal effects

ROSENBAUM, P. R., & RUBIN, D. B. (1983) · Biometrika · doi:10.1093/biomet/70.1.41 · Cited by 31,241

Molecular Chaperone Functions in Protein Folding and Proteostasis

Kim, Y., Hipp, M. S., Bracher, A., Hayer-Hartl, M. K., & Hartl, F. U. (2013) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060208-092442 · Cited by 1,545

Target identification using drug affinity responsive target stability (DARTS)

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Introduction to Danish (nationwide) registers on health and social issues: Structure, access, legislation, and archiving

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Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26 S Proteasome

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RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

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Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

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Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity

Chen, D., Cui, Q. C., Yang, H., & Dou, Q. P. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-2126 · Cited by 683

Cell death assays for drug discovery

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Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice

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Repurposing rosmarinic acid as an anti-colorectal cancer agent through bolstering T cell anti-tumor immunity by enhancing activation of MEK1-mediated TCR signaling

Kang, Z., Li, X., Ma, X., Yan, F., & Wang, Z. (2026) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-026-04366-3 · Cited by 1

Emerging mechanistic insights into cuproptosis in cancer: Metabolic rewiring and therapeutic targeting

Sun, Y., Wei, R., Asiedu, R. K. F., (43671), B. L., & Hu, M. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119615 · Cited by 1

Targeting Copper in Cancer: Chelators to Counteract Cuproplasia and Ionophores to Promote Cuproptosis

Castellano, S., Tosco, A., Milite, C., Viviano, M., Marzo, T., Taliani, S., & Sbardella, G. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6c00884 · Cited by 2

Novel Disulfiram-Loaded Metal–Organic Nanoparticles Inhibit Tumor Growth and Induce Immunogenic Cell Death of Triple-Negative Breast Cancer Cells

Huang, C.-H., Kang, X., Zhou, L., Wang, J., Wu, S.-Y., Sun, P., Wang, Q., Keeton, A. B., Chen, P., & Piazza, G. A. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17111448 · Cited by 1

A Site-Specific Self-Association of a Protein Hub Drives Its Phase Separation

Ahmad, M., Wang, Y.-X., Krishnan, S., Imran, A., Aksimentiev, A., & Movileanu, L. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.5c00424 · Cited by 1

A phase 1b open-label, dose-escalating study of safety and efficacy of disulfiram, copper and vinorelbine in advanced solid tumors

Eefsen, R. L., Stenvang, J., Bartek, J., Pfeiffer, P., Tarpgaard, L. S., Theile, S., Brünner, N., & Nielsen, D. L. (2026) · BMC Cancer · doi:10.1186/s12885-026-15743-7 · Cited by 1

A copper-based ascorbic acid-activatable gel for postoperative glioblastoma therapy

Liu, Y., Chen, Y., Huang, Z., Liu, Z., Wang, C., Lin, H., Zhang, M., & Zhao, C. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114904 · Cited by 1

Targeting programmed cell death: a novel therapeutic paradigm for cancer based on mode-of-death classification

Qiao, X., Ye, T., Wu, T., Han, X., Sun, T., Wang, H., Jia, J., Dai, Y., Yun, R., Jiang, S., et al. (2026) · APOPTOSIS · doi:10.1007/s10495-026-02324-z · Cited by 1

Cold winter, desperate heart: Experience of Great Famine and drinks

Liu, B., Shu, M., Liu, F., Wang, S., 田菁, & Ai, Z. (2026) · Economics & Human Biology · doi:10.1016/j.ehb.2026.101619 · Cited by 1

X-ray-Triggered Prodrug Activation in a Nanoscale Metal–Organic Framework for Spatially Confined Chemoradiotherapy

Xiong, Y., Mao, Y., Deng, C., Wang, C. Y., Li, J., Zhou, Z., & Lin, W. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.6c03407 · Cited by 1

ATP-independent unfolding of ubiquitin by Ufd1 initiates Cdc48/p97-mediated substrate processing

Wang, Y., Zhang, Z., He, W., Wang, P., Du, J., Pan, J., Feng, S., Huang, J., & Ji, Z. (2026) · Nature Structural & Molecular Biology · doi:10.1038/s41594-026-01884-7 · Cited by 1

Retinoic acid in health and disease

Angelis, M. T. D., Dattilo, V., Vono, N., Lise, V., Reda, M., Marco, C. D., Rizzuto, A., Trapasso, F., Viglietto, G., & Santamaria, G. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-03055-y · Cited by 1

Toxicity of disulfiram, a therapeutic agent for chronic alcoholism, to mouse spleen cells

Han, Y. P., & Joo, H. (2018) · Journal of Preventive Veterinary Medicine · doi:10.13041/jpvm.2018.42.4.177 · Cited by 1

Evaluation of the effects of disulfiram, an alcohol-aversive agent with anti-cancer activity, on mouse bone marrow cells

Park, S.-R., & Joo, H. (2022) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2022.26.3.157 · Cited by 1

Disulfiram's journey from rubber vulcanization to T‐cell activation

Dosset, M., & Zanetti, M. (2022) · The EMBO Journal · doi:10.15252/embj.2022111862 · Cited by 2

Design, Synthesis, Biological Evaluation and Molecular Docking Studies of 5-fluorouracil-dithiocarbamate Conjugates

Zhan, Y., Wang, Y., Wang, P., Zhu, H., Guo, H., Sun, H., & Liu, M. (2023) · Letters in Drug Design & Discovery · doi:10.2174/1570180820666230203113746 · Cited by 1

Bioorthogonal Delivery of Carbon Disulfide in Living Cells

Zhao, R., Chen, Y., & Liang, Y. F. (2024) · Angewandte Chemie · doi:10.1002/ange.202400020 · Cited by 1

Bioinformatics prediction and experimental verification identify a cuproptosis-related gene signature as prognosis biomarkers of hepatocellular carcinoma

Wang, W., He, Z., Jia, H., Zhang, J., & Qi, F. (2024) · Translational Cancer Research · doi:10.21037/tcr-23-1561 · Cited by 1

Review of Drug Repositioning in Cancer Therapeutics

Kharwade, S. B., Ruikar, D. B., Manekar, S. S., & Shahane, N. P. (2024) · Asian Journal of Research in Chemistry · doi:10.52711/0974-4150.2024.00042 · Cited by 1

[64Cu]Cu(DDC)2 NPs: A Novel PET Probe for Noninvasive Visualization of NPL4 Expression in Tumors In Vivo

Huang, S., Xiang, L., Shi, D., Chen, X., Ye, S., Liu, X., Yang, Y., Zou, Y., Hu, H., & Wu, H. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.4c01002 · Cited by 1

Repurposing alcohol-abuse drug disulfiram for the treatment of KSHV-infected primary effusion lymphoma by activating antiviral innate immunity

Wang, L., Liu, Z., Xu, Z., Wang, W., Yang, J., Zhang, J., He, S., Liang, Q., & Li, T. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1012957 · Cited by 1

Disulfiram alone regulates the radiosensitivity of lung cancer through NF-κB pathway and regulates the immune microenvironment after radiotherapy by targeting PD-L1 through c-Myc

Cui, Y., Zhang, M., Zhang, S., Cai, Y., 曲延刚, & Luo, L. (2025) · Advances in Cancer Biology - Metastasis · doi:10.1016/j.adcanc.2025.100149 · Cited by 1

The curious case of repurposed remedies

Nelson, B. (2018) · Cancer Cytopathology · doi:10.1002/cncy.22043 · Cited by 1

Structure-activity relationships of novel dithiocarbamates containing α,β-unsaturated ketone fragment as potent anticancer agents

Wang, Y., Li, R., Zhang, H., Zhang, Z., Wang, X., Ge, Z., & Li, R. (2019) · Medicinal Chemistry Research · doi:10.1007/s00044-019-02356-y · Cited by 1

Development of Ubiquitin Tools for Studies of Complex Ubiquitin Processing Protein Machines

Sui, X., & Li, Y. (2019) · Current Organic Chemistry · doi:10.2174/1385272823666191113161511 · Cited by 1

The progression of hepatocyte pyroptosis exacerbates radiation-induced liver disease via the gasdermin D/signal transducer and activator of transcription 5a/CXCL1 axisPreprint

Peng, Z., Dong, A., Wei, G., Liang, Z., Di, Y., Tang, Y., Ling, Y., Li, S., Chen, Y., Zhou, Y., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3161881/v1 · Cited by 1

The rules often neglected in current medicinal chemistry

Cvek, B. (2025) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2025.2465370 · Cited by 1

Faf2/Ubx2 potentiates p97/Cdc48 segregase activity via functional priming and reinforcement of the UT3 domain in Ufd1Preprint

Ren, Y. T., Zheng, Q., Duan, Y., Xu, Z., Qu, Q., Weng, Y., Cui, S. P., Yu, Y., Pan, M., & Liu, L. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.26.708172 · Cited by 1

Anticancer effects of alcohol abuse drug

Crunkhorn, S. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2018.10

Repurposing existing medications in oncology and their potential role in oral cancer

Basile, J., & Czerninski, R. (2018) · Oral Diseases · doi:10.1111/odi.12862

Targeting vulnerabilities through inhibiting the valosin-containing protein (VCP/p97) in ovarian cancer

Bastola, P. (2018) · ProQuest Demo Repository

Disulfiram facilitates ataxin-3 nuclear translocation and potentiates the cytotoxicity in a cell model of SCA3

Wang, Z. (2019) · The Journal of Toxicological Sciences · doi:10.2131/jts.44.535

In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer

Butcher, K. (2019) · Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton)

Why disulfiram is not a panacea?Preprint

Cvek, B. (2020) · doi:10.22541/au.160391342.27202298/v1

Cytochrome P450 Inhibition

Coleman, M. D. (2020) · Wiley eBooks · doi:10.1002/9781119658016.ch5

Developing New Cancer Nanomedicines by Repurposing Old Drugs

Yang, B., & Shi, J. (2020) · Angewandte Chemie · doi:10.1002/ange.202004317

Injectable Hydrogels as a Stem Cell Delivery Platform for Wound Healing

Xu, Q., Sigen, A., & Wang, W. (2022) · Wiley eBooks · doi:10.1002/9783527825820.ch14

Mouse pharmacokinetics and metabolism of the phenylurea thiocarbamate NSC 161128

Koubek, E. J., Kudgus, R. A., Walden, C. A., McGovern, R. M., Covey, J. M., Ames, M. M., & Reid, J. M. (2022) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-022-04440-4

Disulfiram Exerts anti-pulmonary Fibrosis Effect by Activating PGE2 SynthesisPreprint

Pei, X., Zheng, F., Li, Y., Lin, Z., Zhang, Y., Han, X., Feng, Y., Li, F., Yang, J., Li, T., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.04.16.537099

Dual agonism of sodium iodide symporter function in vivoPreprint

Brookes, K., Thornton, C. E. M., Zha, L., Kim, J., Small, B., Manivannan, S., Nieto, H. R., Adcock, H. V., Bottegoni, G., Cox, L. R., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.27.582332

Synthesis, Supramolecular Self-Organization, and Thermal Behavior of the Double Three-Dimensional Pseudo-Polymer Complex [Au{S2CN(CH2)6}2]4[Ag5Cl9] Comprising the New Type Silver(I) Anion

Корнеева, Е. В., Лосева, О. В., Smolentsev, A. I., & Ivanov, A. V. (2024) · Russian Journal of Coordination Chemistry · doi:10.1134/s1070328423600572

Synthesis, Supramolecular Self-Organization, and Thermal Behavior of the Double 3D Pseudo-Polymer Complex [Au{S2CN(CH2)6}2]4[Ag5Cl9] Comprising the New Type Silver(I) Anion

Корнеева, Е. В., Лосева, О. В., Smolentsev, A. I., & Ivanov, A. V. (2024) · Координационная химия · doi:10.31857/s0132344x24010052

Hollow Mesoporous Copper Sulfide Nanoparticles for Cancer Phototherapy

Chu, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-4220-2_7

Clinical Implications of Dually Targeting the Sodium Iodide Symporter in Canonical and Non-Canonical SettingsPreprint

Brookes, K., Thornton, C. E. M., Zha, L., Kim, J., Small, B., Fear, J. S., Nieto, H. R., Adcock, H. V., Jones, A., Pham, T., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4996070

Antioxidant Treatments

Bardaweel, S. K., Banihani, S. A., & Al-Barghouthy, E. (2024) · Springer eBooks · doi:10.1007/978-3-031-69962-7_13

Activation of the NF-κB/ALDH1A1 signaling promotes non-mutational resistance to EGFR-TKIs in non-small cell lung cancer

Zhang, L., Weng, G., Liu, C., Li, Q., Li, J., Wang, Y., Huang, C., Lin, W., Zheng, D., & Ye, Y. (2026) · Oncogene · doi:10.1038/s41388-026-03907-5

Fabrication of calcium phosphate nanoparticles immobilizing copper nanoclusters for in situ synthesis of an anti-cancer agent

Inose, T., Nakamura, M., Wang, X., & Oyane, A. (2025) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2025.136940

DDTC-Cu(I) inhibits human osteosarcoma cells growth by repressing MET/PI3K/AKT signaling pathway

Zhou, R., Yan, L., Zhang, K., Chen, S., Yang, Y. P., Wei, X., Pan, Y., Xu, C., Sun, X., Lv, Z., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-06748-6

Innovative horizons: harnessing drug repositioning for targeted therapeutics in colorectal cancer

Tarin, M., Oryani, M. A., Attarian, F., Sajjadi, S. S., Mehri, A., & Karimi‐Shahri, M. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04289-3

ISLR as a Cuproptosis-Related Predictor and Therapeutic Target in Heart Failure: A Multi-Omics and Bioinformatics Approach

Huang, K., Ding, S., Xu, X., Wang, C., & Han, L. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s490041

Spatial-isolated oil-water biphasic Pickering emulsions inhibit premature disulfiram-copper interaction for enhanced chemo-cuproptosis synergy

Chen, Y., Zhang, J., Ye, H., Shen, S., Wang, J., Wang, J., Li, X., Luo, X., Tao, L., Hu, W. (., et al. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.112187

Additional file 1 of Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells

Cao, H.-Z., Yang, W.-T., & Zheng, P. (2022) · Figshare · doi:10.6084/m9.figshare.19738688

Additional file 3 of Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells

Cao, H.-Z., Yang, W.-T., & Zheng, P. (2022) · Figshare · doi:10.6084/m9.figshare.19738694

Additional file 1 of Co-delivery of nanoparticle and molecular drug by hollow mesoporous organosilica for tumor-activated and photothermal-augmented chemotherapy of breast cancer

Zhang, H., Song, F., Dong, C., Yu, L., Chang, C., & Chen, Y. (2021) · Figshare · doi:10.6084/m9.figshare.16689770

Additional file 1 of LIFU/MMP-2 dual-responsive release of repurposed drug disulfiram from nanodroplets for inhibiting vasculogenic mimicry and lung metastasis in triple-negative breast cancer

Liu, Y., Tang, R., Cao, Y., Wu, N., Qin, Q., Chen, Y., Wei, X., Ren, J., Sun, Y., Zhou, H., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25698198

Additional file 2 of Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells

Cao, H.-Z., Yang, W.-T., & Zheng, P. (2022) · Figshare · doi:10.6084/m9.figshare.19738691

Disulfiram and copper radiosensitizes chordoma by targeting chordoma cancer stem cells and senescent cells

Chen, F., Liu, L., Choy, E., Wang, E., Sadagopan, A., Chen, Y.-L. E., Wang, D., Yang, J., Kizielewicz, N., Yu, L., et al. (2026) · ESMO rare cancers. · doi:10.1016/j.esmorc.2026.100494

Stimuli‐Responsive Heterobimetallic Prodrug Platform Enables In Situ Copper Complex Synthesis and Photosensitizer Activation for Targeted Chemo‐Photodynamic‐Immunotherapy

Huang, Z., Wang, J., Liu, Y., Zheng, D., Lin, H., Li, P., Dai, Y., Luo, Y., Zhang, M., Xu, X., et al. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202529655

METABOLOMIC SIGNATURES IN THE PROGRESSION AND TREATMENT OF SUBSTANCE USE DISORDERS: A BIBLIOMETRIC ANALYSIS

Misnan, E., Rashid, R. B. A., Maw, S. S., & Shah, A. M. (2025) · International Journal of Innovation and Industrial Revolution · doi:10.35631/ijirev.723028

Disulfiram metabolite Cu(DDC)2 enhances radionuclide uptake in vivo revealing insights into tumoural ablation resistance

Brookes, K., Fear, J. S., Thornton, C. E. M., Zha, L., Kim, J., Small, B., Wongsanit, S., Nieto, H. R., Adcock, H. V., Jones, A. P., et al. (2026) · EBioMedicine · doi:10.1016/j.ebiom.2026.106165

Design, Synthesis, and Antitumor Activity of D‐13 Derivatives

Wang, X., Hao, H., Gao, Z., Wang, W., Ma, S., Zhao, Y., & Ji, J. (2026) · ChemistrySelect · doi:10.1002/slct.202506961

When ‘Dirty’ Drugs Become Useful: Peptide-Guided Exposure Engineering for the Repurposing of Cancer Drugs

Marchiò, S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27052400

Self-amplifying RNA therapy encoding CNTF with disulfiram co-delivery promotes optic nerve repair through microglial pyroptosis inhibition and RGC axonal regeneration

Zhang, Q., Liu, Y. K., Wei, Q., Song, M., Liu, S., Zhang, H., Deng, T., Zhang, C., Tan, K., Huang, R., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04272-x

A Magnetic Resonance Imaging Reportable Strategy for In Situ CuET and Mn 2+ Generation to Boost Antitumor Immunity

Zhang, Z., Zhao, Q., Deng, Q., Xu, Q., Lin, H., Zhao, Y., Zelepukin, I. V., Deyev, S. M., Yang, X., & Li, Z. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202526812

CuET Radiosensitizes FAP-Targeted Radioligand Therapy in Lung Cancer by inhibiting DNA RepairPreprint

Xie, J., Zou, Y., Zheng, Y., Shi, D., Zhou, W., Tian, Y., Wang, L., & Wu, H. (2026) · Research Square · doi:10.21203/rs.3.rs-9032718/v1

Etude de la dissémination du cancer colorectal

Belthier, G. (2020) · theses.fr (ABES) · doi:10.70675/041d8f10zf4bcz416bz92b5zc99057a94d09

Bioorthogonal-Inspired In Situ Hydrogel for Nattokinase-Assisted Enhancement of Photothermal-Chemotherapy of Tumors

Liu, J., Xu, D., Wang, Q., Sun, X., Gu, X., Han, B., Zhu, J., Chen, X., Du, F., Chen, H., et al. (2026) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6c00741

In situ generation of copper complex and multivalent CXCR4 inhibitor via ROS-responsive nanoplatform suppresses breast cancer metastasis

Lin, H., Liu, Y., Liu, Z., Luo, Y., Wang, C., Ding, Y., Huang, Z., & Zhao, C. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.05.010

CDCA7–CD44 target pair drives precision elimination of drug-tolerant persister cells in breast cancer

Wu, J., Tang, Z., Liu, J., Liao, B., Liu, W. T., Ma, Z., Ql, M., Zhou, Y., Kong, W., Chen, Q., et al. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.05.015

Repurposing copper diethyldithiocarbamate (CuET) in a polymeric nanofibrous patch for topical therapy of psoriasis

Guo, X., Meng, Q., Liu, W., Rui, H., Ruan, X., Guan, T., Dai, A., Liu, Y., Su, J., & Duan, C. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.127016

Therapeutic potential of drug repurposing in reversing chemoresistance

Panwar, V., & -, A. R. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45717-3.00014-3

Visible-Light-Driven Alkylation of Cycloalkyl Peroxides with Tetrasulfides for the Synthesis of Unsymmetrical Disulfides

Li, W.-J., Li, H., Yang, L., Rao, W., Shen, S.-S., Yang, Z., & Wang, S. (2026) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.6c00834

Disulfiram Alleviates Metabolic Dysfunction-Associated Steatohepatitis in Mice via Inhibiting Aurora Kinase A and Restoring Autophagy

Zhou, Z., Zeng, X., Guo, Y., Tan, Z., Zhang, X., Liu, X., Zheng, S., Liu, W. T., Wang, H. F., & Qi, J. (2026) · Antioxidants · doi:10.3390/antiox15070867

Engineering cuproptosis with nanomedicine: Design, combination therapy, and translation in cancer

Fan, D., Liu, J., Ren, F., Wang, L., Wei, J., Qin, D., Zhou, X., Wu, J., Zou, X., & Wu, A. (2026) · Materials Today Bio · doi:10.1016/j.mtbio.2026.103466

Güncel Biyokimya Çalışmaları X

Şen, M. B., Erikçi, A., DOĞAN, N., Atıcı, Y., Emre, H. Ö., Yurt, E. F., Alpdemir, M., Alpdemir, M. F., Saka, B., Doğan, T., et al. (2026) · Akademisyen Kitabevi eBooks · doi:10.37609/akya.4266

Programmable tumor-selective cuproptosis for in situ cancer vaccination

Song, S., Huang, Z., Zhou, H., Zhang, S., Zhang, Y., Dai, Y., Luo, Z., & Wang, L. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.179635

Design of an activatable unimolecular multicargo prodrug to deliver diethyldithiocarbamate and copper for targeted ovarian cancer therapy

Zhang, M., Huang, Z., Chen, Y., Ding, Y., Lin, H., Zheng, D., Luo, Y., Liu, Y., & Zhao, C. (2026) · Chemical Communications · doi:10.1039/d6cc03070j

AI-Driven Drug Repurposing Strategies for Precision Therapy in Breast Cancer

Jakkula, B. K., & Shyam, P. (2026) · Pharmaceutical science. · doi:10.5772/intechopen.1016336

FAF1 cofactor enhances UFD1/NPL4-p97 unfolding efficiency across ubiquitin chain lengths independent of SUMO2Preprint

Lemmon, A. A., & Lima, C. D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.31.742138

Copper homeostasis and cuproptosis in tumor biology: mechanistic insights and clinical perspectives

Wang, Z. D., Xie, J., Han, Y., Zhang, X., Song, J., Xing, Y., Hou, B., Han, C., & Sui, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1908734

Overcoming Resistance: Targeting Survivin-Driven Apoptotic Resistance Restores Irinotecan Sensitivity in TP53-Mutant Colorectal Cancer

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High-Content Screening Identifies Dithiocarbamates As A Class Of Chemicals That Disrupts TDP-43 ProteostasisPreprint

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