Rational design of cationic lipids for siRNA delivery

Cited by (1,003)

Items 401–500 of 1,003

1. In vivo delivery of plasmid DNA by lipid nanoparticles: the influence of ionizable cationic lipids on organ-selective gene expression
   Azizah Algarni, Emily H. Pilkington, Estelle J. A. Suys, Hareth A. Al-Wassiti, Colin William Pouton, Nghia Phuoc Truong · 2022 · Biomaterials Science
2. Development of mRNA Lipid Nanoparticles: Targeting and Therapeutic Aspects
   Yaping Liu, Yingying Huang, Guantao He, Chun Guo, Jinhua Dong, Linping Wu · 2024 · International Journal of Molecular Sciences
3. CSF transthyretin neuroprotection in a mouse model of brain ischemia
   Sofia Duque Santos, Kate Lykke Lambertsen, Bettina Hjelm Clausen, Akin Akinc, Rene Alvarez, Bente R. Finsen, Maria João Saraiva · 2010 · Journal of Neurochemistry
4. Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA
   Tatsuaki Tagami, Yumi Uehara, Naoto Moriyoshi, Tatsuhiro Ishida, Hiroshi Kiwada · 2011 · Journal of Controlled Release
5. Development of RNAi technology for targeted therapy — A track of siRNA based agents to RNAi therapeutics
   Yinjian Zhou, Chunling Zhang, Wei Ping Liang · 2014 · Journal of Controlled Release
6. Chemistry and formulations for siRNA therapeutics
   Andrzej Gallas, Cameron Alexander, Martyn C. Davies, Sanyogitta Puri, Stephanie Allen · 2013 · Chemical Society Reviews
7. miRNA Delivery by Nanosystems: State of the Art and Perspectives
   Fernanda C. Moraes, Chantal Pichon, Didier Letourneur, Frédéric Chaubet · 2021 · Pharmaceutics
8. Bio-inspired pulmonary surfactant-modified nanogels: A promising siRNA delivery system
   Lynn De Backer, Kevin Braeckmans, Marc C. A. Stuart, Jo Demeester, Stefaan C. De Smedt, Koen Raemdonck · 2015 · Journal of Controlled Release
9. siRNA Delivery: From Lipids to Cell‐penetrating Peptides and Their Mimics
   Matt Gooding, Lorcan Browne, Filipa M. Quinteiro, David L. Selwood · 2012 · Chemical Biology & Drug Design
10. Design of functional nanoparticles by microfluidic platforms as advanced drug delivery systems for cancer therapy
    Antonio Fabozzi, Francesca Della Sala, Mario di Gennaro, Marco Barretta, Gennaro Longobardo, Nicola Solimando, Maurizio Pagliuca, Assunta Borzacchiello · 2023 · Lab on a Chip
11. Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations
    Xinmei Wang, Bo Yu, Wei Ren, Xiaokui Molly Mo, Chenguang Zhou, Hongyan He, HuLiang Jia, Lu Wang, Samson T. Jacob, Robert J. Lee et al. · 2013 · Journal of Controlled Release
12. N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver
    Hongxia Wang, Menghua Xiong, Yucai Wang, Jing Zhu, Jun Wang · 2012 · Journal of Controlled Release
13. Direct Cytosolic Delivery of siRNA Using Nanoparticle‐Stabilized Nanocapsules
    Ying Yan Jiang, Rui Tang, Bradley Duncan, Ziwen Jiang, Bo Yan, Rubul Mout, Vincent M. Rotello · 2014 · Angewandte Chemie International Edition
14. Evolution of nanomedicine formulations for targeted delivery and controlled release
    Sanyogitta Puri, Mariarosa Mazza, Gourgopal Roy, R. England, Liping Zhou, Saghar Nourian, J. Anand Subramony · 2023 · Advanced Drug Delivery Reviews
15. Frameworks for transformational breakthroughs in RNA-based medicines
    John R. Androsavich · 2024 · Nature Reviews Drug Discovery
16. Gene therapy clinical trials worldwide to 2023—an update
    Samantha L. Ginn, Mawj Mandwie, Ian E. Alexander, Michael L. Edelstein, Mohammad R. Abedi · 2024 · The Journal of Gene Medicine
17. Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma
    Sumitaka Yamanaka, Nathaniel R. Campbell, Fangmei An, Scot C. Kuo, James J. Potter, Esteban Mezey, Anirban Maitra, Florin M. Selaru · 2012 · Cell Cycle
18. CD 8 T‐cell priming upon mRNA vaccination is restricted to bone‐marrow‐derived antigen‐presenting cells and may involve antigen transfer from myocytes
    Sandra Lazzaro, Cinzia Giovani, Simona Mangiavacchi, Diletta Magini, Domenico Maione, Barbara C. Baudner, Andrew J. Geall, Ennio De Gregorio, Ugo D’Oro, Cecilia Buonsanti · 2015 · Immunology
19. Use of Nanotechnology to Develop Multi-Drug Inhibitors for Cancer Therapy
    Raghavendra Gowda · 2013 · Journal of Nanomedicine & Nanotechnology
20. Formulation Approaches to Short Interfering RNA and MicroRNA: Challenges and Implications
    Diana Guzman‐Villanueva, Ibrahim mohammed El-sherbiny, Dea Herrera‐Ruiz, Alexander V. Vlassov, Hugh D. C. Smyth · 2012 · Journal of Pharmaceutical Sciences
21. Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts
    Charlotte Julie Caroline Gehin, Javier Montenegro, Eun‐Kyoung Bang, Ana Cajaraville, Shota Takayama, H. Hirose, Shiroh Futaki, Stefan Matile, Howard Riezman · 2013 · Journal of the American Chemical Society
22. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells
    Yunfeng Yan, Li Liu, Hu Xiong, Jason B. Miller, Kejin Zhou, Petra Kós, Kenneth E. Huffman, Sussana A. Elkassih, John W. Norman, Ryan M. Carstens et al. · 2016 · Proceedings of the National Academy of Sciences
23. Recent Advances in Endogenous and Exogenous Stimuli-Responsive Nanocarriers for Drug Delivery and Therapeutics
    Hiroto Hatakeyama · 2017 · Chemical and Pharmaceutical Bulletin
24. Switchable Lipids: Conformational Change for Fast pH‐Triggered Cytoplasmic Delivery
    Warren Viricel, Amira Mbarek, Jeanne Leblond Chain · 2015 · Angewandte Chemie International Edition
25. Lactosylated gramicidin-based lipid nanoparticles (Lac-GLN) for targeted delivery of anti-miR-155 to hepatocellular carcinoma
    Mengzi Zhang, Xiaoju Zhou, Bo Wang, Bryant C. Yung, Ly J. Lee, Kalpana Ghoshal, Robert J. Lee · 2013 · Journal of Controlled Release
26. Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
    Justin B. Lee, Kaixin Zhang, Yuen Yi C. Tam, Ying K. Tam, Nathan M. Belliveau, Vanessa Y.C. Sung, Paulo J.C. Lin, Eric LeBlanc, Marco A. Ciufolini, Paul S. Rennie et al. · 2011 · International Journal of Cancer
27. MicroRNAs in kidney diseases: new promising biomarkers for diagnosis and monitoring
    Francesco Paolo Schena, Grazia Serino, Fabio Sallustio · 2013 · Nephrology Dialysis Transplantation
28. Dual-responsive polyplexes with enhanced disassembly and endosomal escape for efficient delivery of siRNA
    Jia Zhu, Mingxi Qiao, Qi Wang, Yuqing Ye, Shuang Ba, Jingjing Ma, Haiyang Hu, Xiuli Zhao, Dawei Chen · 2018 · Biomaterials
29. Ionizable amino lipid interactions with POPC: implications for lipid nanoparticle function
    Mohsen Ramezanpour, Miranda L. Schmidt, Iulia Bodnariuc, Jayesh A. Kulkarni, Sherry S.W. Leung, Pieter R. Cullis, Jenifer L. Thewalt, D. Peter Tieleman · 2019 · Nanoscale
30. A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer
    Lairong Ding, Junwei Li, Changrong Wu, Feng Yan, Xuemei Li, Shusheng Zhang · 2019 · Journal of Materials Chemistry B
31. Interface Engineering in Multiphase Systems toward Synthetic Cells and Organelles: From Soft Matter Fundamentals to Biomedical Applications
    Zhou Liu, Wen You Zhou, Qi Cheng, Tiantian Kong · 2020 · Advanced Materials
32. Recent progress in mRNA cancer vaccines
    Ruhui Yao, Chunyuan Xie, Xiaojun Xia · 2024 · Human Vaccines & Immunotherapeutics
33. Recent In Vivo Evidences of Particle-Based Delivery of Small-Interfering RNA (siRNA) into Solid Tumors
    Yi Wen, Wilson S. Meng · 2014 · Journal of Pharmaceutical Innovation
34. Novel lipid combination for delivery of plasmid DNA to immune cells in the spleen
    Seigo Kimura, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Hideyoshi Harashima · 2021 · Journal of Controlled Release
35. Bioinert, Stealth or Interactive: How Surface Chemistry of Nanocarriers Determines Their Fate In Vivo
    Julian David Friedl, Valeria Nele, Giuseppe De Rosa, Andreas Bernkop‐Schnürch · 2021 · Advanced Functional Materials
36. siRNA Functionalized Lipid Nanoparticles (LNPs) in Management of Diseases
    Tutu Kalita, Saba Abbasi Dezfouli, Lalit Mohan Pandey, Hasan Uludağ · 2022 · Pharmaceutics
37. Rational design and combinatorial chemistry of ionizable lipids for RNA delivery
    Yue Xu, Alex Golubovic, Shufen Xu, Anni Pan, Bowen Li · 2023 · Journal of Materials Chemistry B
38. Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo
    Sezin Aday, Inbal Hazan‐Halevy, Aránzazu Chamorro-Jorganes, Maryam Anwar, Meir Goldsmith, Nicholas Beazley‐Long, Susmita Sahoo, Navneet Dogra, Walid Sweaad, Francesco Catapano et al. · 2021 · Molecular Therapy
39. Tumor microenvironment-induced structure changing drug/gene delivery system for overcoming delivery-associated challenges
    Min Zhang, Xinli Guo, Mingfu Wang, Kehai Liu · 2020 · Journal of Controlled Release
40. An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates
    Manon Ripoll, Marie‐Clotilde Bernard, Céline Vaure, Emilie Bazin, Sylvie Commandeur, Vladimir Perkov, Katia Lemdani, Marie‐Claire Nicolaï, Patrick Bonifassi, Antoine Kichler et al. · 2022 · Biomaterials
41. mRNA lipid nanoparticle phase transition
    Marius F.W. Trollmann, Rainer A. Böckmann · 2022 · Biophysical Journal
42. Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery
    Lara M. Mollé, Cameron H. Smyth, Daniel Yuen, Angus P. R. Johnston · 2022 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
43. The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism
    Daria M. Strelkova Petersen, Namit Chaudhary, Mariah Lynn Arral, Ryan M. Weiss, Kathryn A. Whitehead · 2023 · European Journal of Pharmaceutics and Biopharmaceutics
44. Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery
    Haiyin Liu, Moore Z. Chen, Thomas J. Payne, Christopher J. H. Porter, Colin William Pouton, Angus P. R. Johnston · 2024 · Advanced Functional Materials
45. Localized, Targeted, and Sustained siRNA Delivery
    Melissa D. Krebs, Eben Alsberg · 2011 · Chemistry - A European Journal
46. Testing thousands of nanoparticles in vivo using DNA barcodes
    Melissa P. Lokugamage, Cory D. Sago, James E. Dahlman · 2018 · Current Opinion in Biomedical Engineering
47. Aggregating particles on the O/W interface: Tuning Pickering emulsion for the enhanced drug delivery systems
    Yali Ming, Yufei Xia, Guanghui Ma · 2022 · Aggregate
48. Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles
    Douglas W. Brown, Ping Wee, Prakash Bhandari, Amirali B. Bukhari, Liliya Grin, Héctor Vega, Maryam Hejazi, Deborah L. Sosnowski, Jailal Ablack, Eileen K. Clancy et al. · 2024 · Cell
49. Biomaterials in siRNA Delivery: A Comprehensive Review
    William Ho, Xue‐Qing Zhang, Xiaoyang Xu · 2016 · Advanced Healthcare Materials
50. RNA delivery biomaterials for the treatment of genetic and rare diseases
    Zhao, Weiyu, Hou, Xucheng, Vick, Olivia G., Dong, Yizhou · 2019 · Biomaterials
51. Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach
    Franziska Freitag, Ernst Wagner · 2020 · Advanced Drug Delivery Reviews
52. Lipid-Based Drug Delivery Nanoplatforms for Colorectal Cancer Therapy
    Chunhua Yang, Didier Merlin · 2020 · Nanomaterials
53. Expanding RNAi to Kidneys, Lungs, and Spleen via Selective ORgan Targeting (SORT) siRNA Lipid Nanoparticles
    Amogh Vaidya, Stephen Moore, Sumanta Chatterjee, Erick Damian Guerrero, Minjeong Kim, Lukas Farbiak, Sean A. Dilliard, Daniel J. Siegwart · 2024 · Advanced Materials
54. Lipid-based vectors for siRNA delivery
    Shubiao Zhang, Defu Zhi, Leaf Huang · 2012 · Journal of drug targeting
55. Regulation of p53‐targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma
    Michael W. Gordon, Fang Yan, Xiaoming Zhong, Pranab Behari Mazumder, Zijun Yidan Xu-Monette, Dehui Zou, Ken H. Young, Kenneth S. Ramos, Yong Li · 2014 · Molecular Carcinogenesis
56. Lung‐Endothelium‐Targeted Nanoparticles Based on a pH‐Sensitive Lipid and the GALA Peptide Enable Robust Gene Silencing and the Regression of Metastatic Lung Cancer
    Mahmoud M. Abd Elwakil, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Kenji Kusumoto, Yusuke Sato, Nour Shobaki, Yasuhiro Kon, Hideyoshi Harashima · 2019 · Advanced Functional Materials
57. Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA
    Xiaoxia Liu, Wei Wang, Dmitry A. Samarsky, Li Liu, Qian Xu, Wenqing Zhang, Guangzu Zhu, Ping Wu, Xialin Zuo, Houliang Deng et al. · 2014 · Nucleic Acids Research
58. Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles
    Rafał Krzysztoń, B. Salem, Dian-Jang Lee, Gerlinde Schwake, Ernst Wagner, Joachim Oskar Rädler · 2017 · Nanoscale
59. Toxicological profile of lipid-based nanostructures: are they considered as completely safe nanocarriers?
    Asaad Azarnezhad, Hadi Samadian, Mehdi Jaymand, Mahsa Sobhani, Amirhossein Ahmadi · 2020 · Critical Reviews in Toxicology
60. Lipid Nanoparticle Delivery Systems to Enable mRNA-Based Therapeutics
    Sean C. Semple, Robert D. Leone, Christopher Barbosa, Ying K. Tam, Paulo J.C. Lin · 2022 · Pharmaceutics
61. Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates
    Yuta Suzuki, Takayuki Miyazaki, Hiroki Muto, Kenji Kubara, Yohei Mukai, Ryuji Watari, Shinya Sato, Keita Kondo, Shin‐ichi Tsukumo, Koji Yasutomo et al. · 2022 · Molecular Therapy — Nucleic Acids
62. The role of helper lipids in optimising nanoparticle formulations of self-amplifying RNA
    Beatriz Dias Barbieri, David J. Peeler, Karnyart Samnuan, Suzanne Day, Kai Hu, Hadijatou Sallah, John S. Tregoning, Paul F. McKay, Robin J. Shattock · 2024 · Journal of Controlled Release
63. Lipid Nanoparticles Composed of Quaternary Amine–Tertiary Amine Cationic Lipid Combination (QTsome) for Therapeutic Delivery of AntimiR-21 for Lung Cancer
    Bryant C. Yung, Jilong Li, Mengzi Zhang, Xinwei Cheng, Hong Li, Elaine M. Yung, Kang Chen, Lauren E. Cosby, Yang Liu, Lesheng Teng et al. · 2016 · Molecular Pharmaceutics
64. Scaffolds as Structural Tools for Bone-Targeted Drug Delivery
    Riccardo Ferracini, Isabel Martínez-Herreros, Antonio Russo, Tommaso Casalini, Filippo Rossi, Giuseppe Perale · 2018 · Pharmaceutics
65. Self‐Assembled Nanomedicines for Anticancer and Antibacterial Applications
    Lingyun Zhou, Tian Autumn Qiu, Fengting Lv, Libing Liu, Jianming Ying, Shu Wang · 2018 · Advanced Healthcare Materials
66. In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
    Sumiyo T. Watanabe, Kotaro Hayashi, Kazuko Toh, Hyun Jin Kim, Xueying Liu, Hiroyuki Chaya, Shigeto Fukushima, Keisuke Katsushima, Yutaka Kondo, Satoshi Uchida et al. · 2019 · Nature Communications
67. Mechanistic Studies of an Automated Lipid Nanoparticle Reveal Critical Pharmaceutical Properties Associated with Enhanced mRNA Functional Delivery In Vitro and In Vivo
    Lili Cui, Morag Rose Hunter, Silvia Sonzini, Sara G. T. Pereira, Steven M. Romanelli, Kai Liu, Weimin Li, Lihuan Liang, Bin Yang, Najet Mahmoudi et al. · 2021 · Small
68. Chemical Approaches to Synthetic Drug Delivery Systems for Systemic Applications
    Daniel Braatz, Mariam Cherri, Michael Tully, Mathias Dimde, Guoxin Ma, Ehsan Mohammadifar, Felix Reisbeck, Vahid Ahmadi, Michael Schirner, Rainer Haag · 2022 · Angewandte Chemie International Edition
69. Pharmaceutical liposomal delivery—specific considerations of innovation and challenges
    Taoxing Peng, Weihua Xu, Qianqian Li, Yang Ding, Yongzhuo Huang · 2022 · Biomaterials Science
70. The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice
    Hiroto Hatakeyama, Manami Murata, Yusuke Sato, Mayumi M. Takahashi, Noriaki Minakawa, Akira Matsuda, Hideyoshi Harashima · 2013 · Journal of Controlled Release
71. Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands
    Zubao Gan, Melissa P. Lokugamage, Marine Z. C. Hatit, David Loughrey, Kalina Paunovska, Manaka Sato, Ana Cristian, James E. Dahlman · 2020 · Bioengineering & Translational Medicine
72. In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors
    Xuexiang Han, Junchao Xu, Ying Xu, Mohamad‐Gabriel Alameh, Lulu Xue, Ningqiang Gong, Rakan D. El-Mayta, Rohan Palanki, Claude C. Warzecha, Gan Zhao et al. · 2024 · Nature Communications
73. Co-delivery of small molecule hedgehog inhibitor and miRNA for treating liver fibrosis
    Virender Kumar, Goutam Mondal, Rinku Dutta, Ram I. Mahato · 2015 · Biomaterials
74. Biocompatible Mesoporous and Soft Nanoarchitectures
    Angelina Angelova, Borislav Angelov, Rada Mutafchieva, Sylviane Lesieur · 2014 · Journal of Inorganic and Organometallic Polymers and Materials
75. Efficient hepatic delivery and protein expression enabled by optimized mRNA and ionizable lipid nanoparticle
    Tongren Yang, Chunhui Li, Xiaoxia Wang, Deyao Zhao, Mengjie Zhang, Huiqing Cao, Zicai Liang, Haihua Xiao, Xing‐Jie Liang, Yuhua Weng et al. · 2020 · Bioactive Materials
76. Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
    Adam Bohr, Nicolas Tsapis, Camilla Foged, Ilaria Andreana, Mingshi Yang, Elias Fattal · 2020 · European Journal of Pharmaceutics and Biopharmaceutics
77. mRNA Cancer Vaccines: Construction and Boosting Strategies
    Xiaoqing Liu, Pei Huang, Rusen Yang, Hongzhang Deng · 2023 · ACS Nano
78. Design, preparation and application of nucleic acid delivery carriers
    Jun Yang, Hongmei Liu, Xin Zhang · 2013 · Biotechnology Advances
79. pH-Sensitive Nanomicelles for High-Efficiency siRNA Delivery in Vitro and in Vivo: An Insight into the Design of Polycations with Robust Cytosolic Release
    Junhui Zhou, Yidi Wu, Changrong Wang, Qiang Cheng, Shangcong Han, Xiaoxia Wang, Jianhua Zhang, Liandong Deng, Deyao Zhao, Lili Du et al. · 2016 · Nano Letters
80. Targeted Co‐delivery of PTX and TR3 siRNA by PTP Peptide Modified Dendrimer for the Treatment of Pancreatic Cancer
    Yang Li, Hebin Wang, Kai Wang, Qinglian Hu, Qi Zheng Yao, Youqing Shen, Guocan Yu, Guping Tang · 2016 · Small
81. A drug-self-gated and tumor microenvironment-responsive mesoporous silica vehicle: “four-in-one” versatile nanomedicine for targeted multidrug-resistant cancer therapy
    Wei Cheng, Chaoyu Liang, Xusheng Wang, Hsiang‐i Tsai, Gan Liu, Yunmei Peng, Junpeng Nie, Laiqiang Huang, Lin Mei, Xiaowei Zeng · 2017 · Nanoscale
82. Lipid Nanoparticles for Organ-Specific mRNA Therapeutic Delivery
    Magdalena M. Żak, Lior Zangi · 2021 · Pharmaceutics
83. Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing
    Matthew N. O’Brien, Antonio P. Costa, Yareli Maciel Cebrero, Johnson Joseph, Apoorva Sarode, Nanzhi Zang, Lee Joon Kim, Kate Hofmann, Shirley Wang, Alexandre Goyon et al. · 2023 · Molecular Pharmaceutics
84. Genetically engineered T cells bearing chimeric nanoconstructed receptors harboring TAG-72-specific camelid single domain antibodies as targeting agents
    Zahra Sharifzadeh, Fatemeh Rahbarizadeh, Mohammad Ali Shokrgozar, Davoud Ahmadvand, Fereidoun Mahboudi, Fatemeh Rahimi Jamnani, Seyed Moein Moghimi · 2012 · Cancer Letters
85. Enzyme-Catalyzed One-Step Synthesis of Ionizable Cationic Lipids for Lipid Nanoparticle-Based mRNA COVID-19 Vaccines
    Zhongyu Li, Xue‐Qing Zhang, William Ho, Fengqiao Li, Mingzhu Gao, Xin Bai, Xiaoyang Xu · 2022 · ACS Nano
86. Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery
    Zhao Gan, Lulu Xue, Hannah C. Geisler, Junchao Xu, Xinyuan Li, Michael J. Mitchell, Andrew E. Vaughan · 2024 · Proceedings of the National Academy of Sciences
87. Unlocking the Therapeutic Applicability of LNP-mRNA: Chemistry, Formulation, and Clinical Strategies
    Xiaonan Huang, Yishan Ma, Guanghui Ma, Yufei Xia · 2024 · Research
88. Nucleic acid therapeutics: Past, present, and future
    Sajid Naeem, Ju Zhang, Yang Zhang, Yu Wang · 2024 · Molecular Therapy — Nucleic Acids
89. Storage stability of optimal liposome–polyethylenimine complexes (lipopolyplexes) for DNA or siRNA delivery
    Alexander Ewe, Andreas Schaper, Sabine Barnert, Rolf Schubert, Achim Temme, Udo Bakowsky, Achim Michael Aigner · 2014 · Acta Biomaterialia
90. Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model
    Chunting Ye, Jang‐Gi Choi, Sojan Abraham, Haoquan Wu, Dolores Diaz, Daniel A. Terreros, Premlata Shankar, N. Manjunath · 2012 · Proceedings of the National Academy of Sciences
91. Non‐Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co‐Delivery of Cas9 mRNA and sgRNA
    Jason B. Miller, Shuyuan Zhang, Petra Kós, Hu Xiong, Kejin Zhou, Sofya S. Perelman, Hao Zhu, Daniel J. Siegwart · 2016 · Angewandte Chemie
92. Neuroblastoma-targeted Nanoparticles Entrapping siRNA Specifically Knockdown ALK
    Daniela Di Paolo, Chiara Brignole, Fabio Pastorino, Roberta Carosio, Alessia Zorzoli, Marzia Rossi, Monica Loi, Gabriella Pagnan, Laura Emionite, Michele Cilli et al. · 2011 · Molecular Therapy
93. Promising effects of nanomedicine in cancer drug delivery
    Rajesh R. Wakaskar · 2017 · Journal of drug targeting
94. Efficient delivery of VEGF-A mRNA for promoting diabetic wound healing via ionizable lipid nanoparticles
    Wenhui Zha, Ji Wang, Zongke Guo, Yanhao Zhang, Yang Wang, Shuo Dong, Chao Liu, Hanlei Xing, Xinsong Li · 2022 · International Journal of Pharmaceutics
95. Comparative analysis of lipid Nanoparticle-Mediated delivery of CRISPR-Cas9 RNP versus mRNA/sgRNA for gene editing in vitro and in vivo
    Johanna Walther, Deja Porenta, Danny Wilbie, Cornelis W. Seinen, Naomi Benne, Qiangbing Yang, Olivier G. de Jong, Zhiyong Lei, Enrico Mastrobattista · 2024 · European Journal of Pharmaceutics and Biopharmaceutics
96. Delivery Strategy to Enhance the Therapeutic Efficacy of Liver Fibrosis via Nanoparticle Drug Delivery Systems
    Liu, Jie, Liu, Jinhu, Mu, Weiwei, Ma, Qingping, Zhai, Xiangyu, Jin, Bin, Liu, Yongjun, Zhang, Na · 2024 · ACS Nano
97. Liposomal lipid nanoparticles for extrahepatic delivery of mRNA
    Miffy H. Y. Cheng, Yao Zhang, Kevin Fox, Jerry Leung, Colton Strong, Emma Kang, Yihang Chen, Michelle Tong, Hemashree Bommadevara, Eric Jan et al. · 2025 · Nature Communications
98. The influence of the polar head-group of synthetic cationic lipids on the transfection efficiency mediated by niosomes in rat retina and brain
    Edilberto Ojeda, Gustavo Puras, Mireia Agirre, Jon Zárate Sesma, Santiago Grijalvo, Ramón Eritja, Gema Martı́nez, Cristina Soto‐Sánchez, Ariadna Díaz‐Tahoces, Marcelino Avilés‐Trigueros et al. · 2015 · Biomaterials
99. One Size Does Not Fit All: The Effect of Chain Length and Charge Density of Poly(ethylene imine) Based Copolymers on Delivery of pDNA, mRNA, and RepRNA Polyplexes
    Anna K. Blakney, Gökhan Yilmaz, Paul F. McKay, C. Remzi Becer, Robin J. Shattock · 2018 · Biomacromolecules
100. Bottlebrush-architectured poly(ethylene glycol) as an efficient vector for RNA interference in vivo
     Dali Wang, Jiaqi Lin, Fei Jia, Xuyu Tan, Yuyan Wang, Xiaoya Sun, Xueyan Cao, Fangyuan Che, Hao Lü, Ximing Gao et al. · 2019 · Science Advances