High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

Pattanayak, Vikram, Lin, Steven, Guilinger, John P, Ma, Enbo, Doudna, Jennifer A, Liu, David R·2013·Nature Biotechnology

Cited by (1,002)

Items 401–500 of 1,002

  1. Functional validation of mouse tyrosinase non-coding regulatory DNA elements by CRISPR–Cas9-mediated mutagenesis
    Davide Seruggia, Almudena Fernández, Marta Cantero, Paweł Pelczar, Lluı́s Montoliu · 2015 · Nucleic Acids Research
  2. Off-Target Analysis in Gene Editing and Applications for Clinical Translation of CRISPR/Cas9 in HIV-1 Therapy
    Andrew Atkins, Cheng-Han Chung, Alexander G. Allen, Will Dampier, Theodore E. Gurrola, Ilker Kudret Sariyer, Michael R. Nonnemacher, Brian L. Wigdahl · 2021 · Frontiers in Genome Editing
  3. CRISPR/Cas9 in lepidopteran insects: Progress, application and prospects
    Jiangjie Li, Yan Shi, Jinan Wu, Hao Li, Guy J. Smagghe, Tong‐Xian Liu · 2021 · Journal of Insect Physiology
  4. Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus
    Kun Xu, Chonghua Ren, Zhongtian Liu, Tao Zhang, Tingting Zhang, Duo Li, Ling Wang, Qiang Yan, Lijun Guo, Juncen Shen et al. · 2014 · Cellular and Molecular Life Sciences
  5. Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update
    Lin, Fan-Li, Wang, Peng-Yuan, Chuang, Yu-Fan, Wang, Jiang-Hui, Wong, Vickie H.Y., Bui, Bang V., Liu, Guei-Sheung · 2020 · Molecular Therapy
  6. Direct Injection of CRISPR/Cas9-Related mRNA into Cytoplasm of Parthenogenetically Activated Porcine Oocytes Causes Frequent Mosaicism for Indel Mutations
    Masahiro Sato, Miyu Koriyama, Satoshi Watanabe, Masato Ohtsuka, Takayuki Sakurai, Emi Inada, Issei Saitoh, Shingo Nakamura, K. Miyoshi · 2015 · International Journal of Molecular Sciences
  7. CRISPR-Cas9 technology: applications and human disease modelling
    Raúl Torres-Ruiz, Sandra Rodríguez · 2016 · Briefings in Functional Genomics
  8. CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects
    César de la Fuente‐Núñez, Timothy K. Lu · 2016 · Integrative Biology
  9. Strategies for In Vivo Genome Editing in Nondividing Cells
    Fatemeharefeh Nami, Mohsen Basiri, Leila Satarian, Cameron Curtiss, Hossein Baharvand, Catherine M. Verfaillie · 2018 · Trends in biotechnology
  10. Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?
    Alex M. Zimmer, Yihang Kevin Pan, Theanuga Chandrapalan, Raymond W. M. Kwong, Steve F. Perry · 2019 · Journal of Experimental Biology
  11. Evaluation and rational design of guide RNAs for efficient CRISPR/Cas9-mediated mutagenesis in Ciona
    Shashank Gandhi, Maximilian Haeussler, Florian Razy‐Krajka, Lionel Christiaen, Alberto Stolfi · 2017 · Developmental Biology
  12. Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPR/Cas9-Induced Homology-Directed Repair in Zygotes
    Xiaoyang Zhou, Lulu Wang, Yinan Du, Fei Xie, Liang Li, Yu Liu, Chuanhong Liu, Shi‐Qiang Wang, Shi‐Bing Zhang, Xingxu Huang et al. · 2015 · Human Mutation
  13. DNA Nanostructure‐Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides
    Qinqin Hu, Sheng Wang, Lihua Wang, Hongzhou Gu, Chunhai Fan · 2018 · Advanced Healthcare Materials
  14. Detection of target DNA with a novel Cas9/sgRNAs-associated reverse PCR (CARP) technique
    Beibei Zhang, Qiao Wang, Xinhui Xu, Qiang Xia, Feifei Long, Weiwei Li, Yingchun Shui, Xinyi Xia, Jinke Wang · 2018 · Analytical and Bioanalytical Chemistry
  15. Distinct patterns of Cas9 mismatch tolerancein vitroandin vivo
    Becky Xu Hua Fu, Robert P. St.Onge, Andrew Z. Fire, Justin Smith · 2016 · Nucleic Acids Research
  16. Single and multiple gene knockouts by CRISPR–Cas9 in maize
    Doll, Nicolas M., Gilles, Laurine M., Gérentes, Marie-France, Richard, Christelle, Just, Jeremy, Fierlej, Yannick, Borrelli, Virginia M. G., Gendrot, Ghislaine, Ingram, Gwyneth C., Rogowsky, Peter M. et al. · 2019 · Plant Cell Reports
  17. Class 2 CRISPR–Cas RNA-guided endonucleases: Swiss Army knives of genome editing
    Stefano Stella, Pablo Alcón, Guillermo Montoya · 2017 · Nature Structural & Molecular Biology
  18. Applicability of the EFSA Opinion on site‐directed nucleases type 3 for the safety assessment of plants developed using site‐directed nucleases type 1 and 2 and oligonucleotide‐directed mutagenesis
    EFSA Panel on Genetically Modified Organisms (EFSA GMO Panel), Hanspeter Naegeli, JL Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M. Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejátko, Francisco Javier Moreno et al. · 2020 · EFSA Journal
  19. Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment
    Seung-Hun Kang, Wi-jae Lee, Ju-Hyun An, Jong‐Hee Lee, Young-Hyun Kim, Hanseop Kim, Yeounsun Oh, Young‐Ho Park, Yeung Bae Jin, Bong‐Hyun Jun et al. · 2020 · Nature Communications
  20. Targeting Non-Coding RNAs in Plants with the CRISPR-Cas Technology is a Challenge yet Worth Accepting
    Jolly Basak, Chandran Nithin · 2015 · Frontiers in Plant Science
  21. Production of hypoallergenic milk from DNA-free beta-lactoglobulin (BLG) gene knockout cow using zinc-finger nucleases mRNA
    Zhaolin Sun, Ming Wang, Shiwen Han, Shuangyu Ma, Zhiyuan V. Zou, Fangrong Ding, Xinrui Li, Ling Li, Bo Tang, Haiping Wang et al. · 2018 · Scientific Reports
  22. Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
    Jenny Shapiro, Ortal Iancu, Ashley M. Jacobi, Matthew McNeill, Rolf Turk, Garrett R. Rettig, Ido Amit, Adi Tovin, Zohar Yakhini, Mark A. Behlke et al. · 2020 · Molecular Therapy — Methods & Clinical Development
  23. New prospects on the horizon: Genome editing to engineer plants for desirable traits
    Zahra Iqbal, Mohammed Shariq Iqbal, Ausaf Ahmad, Anjuman Gul Memon, Mohammad Israil Ansari · 2020 · Current Plant Biology
  24. Current Bioinformatics Tools to Optimize CRISPR/Cas9 Experiments to Reduce Off-Target Effects
    Naeem, Muhammad, Alkhnbashi, Omer S. · 2023 · International Journal of Molecular Sciences
  25. Determining the Specificities of TALENs, Cas9, and Other Genome-Editing Enzymes
    Vikram Pattanayak, John P. Guilinger, David R. Liu · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
  26. New breeding technique “genome editing” for crop improvement: applications, potentials and challenges
    Supriya Babasaheb Aglawe, Kalyani Makarand Barbadikar, Satendra Kumar Mangrauthia, Maganti Sheshu Madhav · 2018 · 3 Biotech
  27. Mutation at Different Sites of Metal Transporter Gene OsNramp5 Affects Cd Accumulation and Related Agronomic Traits in Rice (Oryza sativa L.)
    Tiankang Wang, Yixing Li, Yuefeng Fu, Hongjun Xie, Shufeng Song, Mudan Qiu, Jiong Wen, Muwen Chen, Ge Chen, Yan Tian et al. · 2019 · Frontiers in Plant Science
  28. CRISPR/Cas9 gene-editing strategies in cardiovascular cells
    Eva Vermersch, Charlène Jouve, Jean‐Sébastien Hulot · 2019 · Cardiovascular Research
  29. Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep
    Rui Zhang, Yan Li, Kun Jia, Xueling Xu, Yao Li, Yue Zhao, Xiaosheng Zhang, Jinlong Zhang, Guoshi Liu, Shoulong Deng et al. · 2020 · Cell Death and Disease
  30. CRISPR–Cas system: a powerful tool for genome engineering
    Liang Liu, Xiu-Duo Fan · 2014 · Plant Molecular Biology
  31. RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing?
    Giedrius Gasiūnas, Virginijus Šikšnys · 2013 · Trends in Microbiology
  32. Expansion of the CRISPR–Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs
    Vinod Jaskula-Ranga, Karl J. Wahlin, Julien Maruotti, Donald J. Zack · 2014 · Nature Communications
  33. Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection
    Benjamin Steyer, Qian Bu, Evan Cory, Keer Jiang, Stella Duong, Divya Sinha, Stephanie S. Steltzer, David M. Gamm, Qiang Chang, Krishanu Saha · 2018 · Stem Cell Reports
  34. Fine-Tuning Next-Generation Genome Editing Tools
    Chidananda Nagamangala Kanchiswamy, Massimo Emilio Maffei, Mickaël Malnoy, Riccardo Velasco, Jin‐Soo Kim · 2016 · Trends in biotechnology
  35. Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls
    Dina Simkin, Vasileios Papakis, Bernabé I. Bustos, Christina M. Ambrosi, Steven J. Ryan, Valeriya Baru, Luis A. Williams, Graham T. Dempsey, Owen B. McManus, John E. Landers et al. · 2022 · Stem Cell Reports
  36. DNase H Activity of Neisseria meningitidis Cas9
    Yan Zhang, Rakhi Rajan, H. Steven Seifert, Alfonso Mondragón, Erik J. Sontheimer · 2015 · Molecular Cell
  37. Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management
    Khaled S. Allemailem, Mohammed A. Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan · 2022 · 癌症:英文版
  38. Resources for Functional Genomics Studies in Drosophila melanogaster
    Stephanie Elizabeth Mohr, Yanhui Hu, Kevin Kim, Benjamin E. Housden, Norbert Perrimon · 2014 · Genetics
  39. A comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies
    Luke Hoberecht, Pirunthan Perampalam, Aaron T. L. Lun, Jean‐Philippe Fortin · 2022 · Nature Communications
  40. Metabolic Engineering of Yarrowia lipolytica for Terpenoid Production: Tools and Strategies
    Tang-Lei Zhang, Hongwei Yu, Lidan Ye · 2023 · ACS Synthetic Biology
  41. Efficient generation of genome-modified mice via offset-nicking by CRISPR/Cas system
    Wataru Fujii, Asuka Onuma, Koji Sugiura, Kunihiko Naito · 2014 · Biochemical and Biophysical Research Communications
  42. Landscape of target:guide homology effects on Cas9-mediated cleavage
    Becky Xu Hua Fu, Loren L Hansen, Karen L. Artiles, Michael L. Nonet, Andrew Z. Fire · 2014 · Nucleic Acids Research
  43. A morphospace for synthetic organs and organoids: the possible and the actual
    Aina Ollé-Vila, Salva Duran‐Nebreda, Núria Conde Pueyo, Raúl Montañez, Ricard V. Solé · 2016 · Integrative Biology
  44. Bioethanol production from cereal crops and lignocelluloses rich agro-residues: prospects and challenges
    S. P. Jeevan Kumar, N. S. Sampath Kumar, Anjani Devi Chintagunta · 2020 · SN Applied Sciences
  45. CRISPR/Cas9 for Sickle Cell Disease: Applications, Future Possibilities, and Challenges
    Selami Demirci, Alexis Kristine Leonard, Juan J. Haro‐Mora, Naoya Uchida, John F. Tisdale · 2019 · Advances in experimental medicine and biology
  46. Genome editing in cardiovascular diseases
    Indra Mani · 2021 · Progress in molecular biology and translational science
  47. Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
    Xiaoqiang Huang, Dongshan Yang, Jifeng Zhang, Jie Xu, Y. Eugene Chen · 2022 · Cells
  48. From bench to bedside: cutting-edge applications of base editing and prime editing in precision medicine
    Weihui Xu, Shiyao Zhang, Huan Qin, Kai Yao · 2024 · Journal of Translational Medicine
  49. The iCRISPR Platform for Rapid Genome Editing in Human Pluripotent Stem Cells
    Zeng‐Rong Zhu, Federico Gonzãlez, Danwei Huangfu · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
  50. Nuclease‐mediated genome editing: At the front‐line of functional genomics technology
    Tetsushi Sakuma, Knut Woltjen · 2014 · Development Growth & Differentiation
  51. Carbon Nitride Nanosheet-Supported Porphyrin: A New Biomimetic Catalyst for Highly Efficient Bioanalysis
    Shengyuan Deng, Pei-Xin Yuan, Xubo Ji, Dan Shan, Xueji Zhang · 2014 · ACS Applied Materials & Interfaces
  52. Cas9 cleavage assay for pre-screening of sgRNAs using nicking triggered isothermal amplification
    Kaixiang Zhang, Ruijie Deng, Yue Li, Ling Zhang, Jinghong Li · 2016 · Chemical Science
  53. Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancers
    Rui Lopes, Gözde Korkmaz, Reuven Agami · 2016 · Nature Reviews Molecular Cell Biology
  54. Biomolecular condensates: Formation mechanisms, biological functions, and therapeutic targets
    Xin Niu, Lei Zhang, Yuchen Wu, Zhi Zong, Bin Wang, Jisheng Liu, Long Zhang, Fangfang Zhou · 2023 · MedComm
  55. Application of CRISPR/Cas9 genome editing to the study and treatment of disease
    Andrea Pellagatti, Hamid Dolatshad, Simona Valletta, Jacqueline Boultwood · 2015 · Archives of Toxicology
  56. Designed nucleases for targeted genome editing
    Junwon Lee, Jae‐Hee Chung, Ho Min Kim, Seokjoong Kim, Seokjoong Kim · 2015 · Plant Biotechnology Journal
  57. The genome editing revolution: A CRISPR‐Cas TALE off‐target story
    Stefano Stella, Guillermo Montoya · 2016 · BioEssays
  58. Precision genetic modifications: a new era in molecular biology and crop improvement
    Franziska Fichtner, Reynel Urrea-Castellanos, Bekir Ülker · 2014 · Planta
  59. Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies
    Nadia Sukusu Nielsen, Ebbe Toftgaard Poulsen, Marie Vestergaard Lukassen, Connie Chao-Shern, Emilie Hage Mogensen, Christian Enrico Rusbjerg-Weberskov, Larry DeDionisio, Leif Schauser, Tara Moore, Daniel E. Otzen et al. · 2020 · Progress in Retinal and Eye Research
  60. Prophages are associated with extensive CRISPR–Cas auto-immunity
    Franklin L. Nóbrega, Hielke Walinga, Bas E. Dutilh, Stan J. J. Brouns · 2020 · Nucleic Acids Research
  61. Error-corrected next generation sequencing – Promises and challenges for genotoxicity and cancer risk assessment
    Francesco Marchetti, Renato Cardoso, Connie L. Chen, George R. Douglas, Joanne M. Elloway, Patricia A. Escobar, Tod A. Harper, Robert H. Heflich, Darren Kidd, Anthony M. Lynch et al. · 2023 · Mutation Research/Reviews in Mutation Research
  62. Off‐target assessment of CRISPR ‐ C as9 guiding RNA s in human i PS and mouse ES cells
    E‐Pien Tan, Yilong Li, Martin Del Castillo Velasco‐Herrera, Kosuke Yusa, Allan Bradley · 2014 · genesis
  63. Gene-knocked out chimeric antigen receptor (CAR) T cells: Tuning up for the next generation cancer immunotherapy
    Hamid Reza Mirzaei, Hossein Pourghadamyari, Majid Rahmati, Abbas Mohammadi, Javid Sadri Nahand, Abbas Rezaei, Hamed Mirzaei, Jamshid Hadjati · 2018 · Cancer Letters
  64. Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS
    Han‐Xiang Deng, Hong Zhai, Yong Shi, Guoxiang Liu, Jessica Lowry, Bin Liu, Éanna B. Ryan, Jianhua Yan, Yi Yang, Nigel Zhang et al. · 2021 · Communications Biology
  65. ON-Target Adverse Events of CRISPR-Cas9 Nuclease: More Chaotic than Expected
    Julian Boutin, David Cappellen, Juliette Rosier, Samuel Amintas, Sandrine Dabernat, Aurélie Bedel, François Moreau‐Gaudry · 2022 · The CRISPR Journal
  66. CRISPR nuclease off-target activity and mitigation strategies
    Beeke Wienert, M. Kyle Cromer · 2022 · Frontiers in Genome Editing
  67. Exploiting CRISPR / C as systems for biotechnology
    Timothy Robert Sampson, David S. Weiss · 2013 · BioEssays
  68. Genome Editing with CRISPR-Cas9: Can It Get Any Better?
    Maximilian Haeussler, Jean‐Paul Concordet · 2016 · Journal of genetics and genomics/Journal of Genetics and Genomics
  69. Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells
    B. Madison, Deepak Patil, Maximilian Richter, Xianghong Li, Min Tong, S. Cranert, Xin-Xin Wang, Renata M. Martin, Hai-Bin Xi, Yening Tan et al. · 2022 · Molecular Therapy: Nucleic Acids
  70. Redesign of extensive protein–DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization
    Ryo Takeuchi, Michael Y. Choi, Barry L. Stoddard · 2014 · Proceedings of the National Academy of Sciences
  71. Towards a CRISPR view of early human development: applications, limitations and ethical concerns of genome editing in human embryos
    Álvaro Plaza Reyes, Fredrik Lanner · 2017 · Development
  72. Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems
    Akihiro Yasue, Silvia Naomi Mitsui, Takahito Watanabe, Tetsushi Sakuma, Seiichi Oyadomari, Takashi Yamamoto, Sumihare Noji, Taro Mito, Eiji I. Tanaka · 2014 · Scientific Reports
  73. Staying on target with CRISPR-Cas
    Dana Carroll · 2013 · Nature Biotechnology
  74. Endonucleases: new tools to edit the mouse genome
    Tobias Wijshake, Darren J. Baker, Bart van de Sluis · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  75. Essential RNA-Based Technologies and Their Applications in Plant Functional Genomics
    Sachin Teotia, Deepali Singh, Xiaoqing Tang, Guiliang Tang · 2016 · Trends in biotechnology
  76. Delivery Approaches for Therapeutic Genome Editing and Challenges
    Ilayda Ates, Tanner Rathbone, Callie Stuart, P. Hudson Bridges, Renee N. Cottle · 2020 · Genes
  77. CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities
    Bhaskar Roy, Jing Crystal Zhao, Chao Yang, Wen Luo, Teng Xiong, Yong Li, Xiaodong Fang, Guanjun Gao, Chabungbam Orville Singh, Lise Madsen et al. · 2018 · Frontiers in Genetics
  78. Evaluation of mutation rates, mosaicism and off target mutations when injecting Cas9 mRNA or protein for genome editing of bovine embryos
    Sadie L. Hennig, Joseph R. Owen, Jason Ching‐Yao Lin, Amy E Young, Pablo J. Ross, Alison Louise Van Eenennaam, James D. Murray · 2020 · Scientific Reports
  79. Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement
    Evan A. Boyle, Winston R. Becker, Hua Bai, Janice S. Chen, Jennifer A. Doudna, William James Greenleaf · 2021 · Science Advances
  80. Evolution and Application of Genome Editing Techniques for Achieving Food and Nutritional Security
    Sajid Fiaz, Sunny Ahmar, Sajjad Saeed, Aamir Riaz, Freddy Mora, Ki‐Hong Jung · 2021 · International Journal of Molecular Sciences
  81. Current trends of clinical trials involving CRISPR/Cas systems
    Song‐Yang Zhang, Yidi Wang, Dezhi Mao, Yue Wang, Hong Zhang, Yihan Pan, Yuezeng Wang, Shuzhi Teng, Ping Huang · 2023 · Frontiers in Medicine
  82. Engineering strategies to safely drive CAR T-cells into the future
    Matteo Rossi, Eytan Breman · 2024 · Frontiers in Immunology
  83. Precision genome editing: A small revolution for glycobiology
    Catharina Steentoft, Eric Bennett, Katrine T.-B. G. Schjoldager, Sergey Y. Vakhrushev, Hans Heugh Wandall, Henrik Clausen · 2014 · Glycobiology
  84. Discovering and validating cancer genetic dependencies: approaches and pitfalls
    Ann Lin, Jason M. Sheltzer · 2020 · Nature Reviews Genetics
  85. Biallelic Editing of the LOB1 Promoter via CRISPR/Cas9 Creates Canker-Resistant ‘Duncan’ Grapefruit
    Hongge Jia, Ahmad A. Omar, Vladimir Orbović, Nian Wang · 2021 · Phytopathology
  86. Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs
    John C. Rose, Nicholas A. Popp, Chris D. Richardson, Jason J. Stephany, Julie Mathieu, Cindy T. Wei, Jacob E. Corn, Dustin J. Maly, Douglas M. Fowler · 2020 · Nature Communications
  87. Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy
    Divya Sinha, Benjamin Steyer, Pawan Kumar Shahi, Katherine P. Mueller, Rasa Valiauga, Kimberly L. Edwards, Cole Bacig, Stephanie S. Steltzer, Sandhya Srinivasan, Amr A. Abdeen et al. · 2020 · The American Journal of Human Genetics
  88. Recent advances in therapeutic gene-editing technologies
    Dongqi Liu, Di Cao, Renzhi Han · 2025 · Molecular Therapy
  89. Advances in genome editing technology and its promising application in evolutionary and ecological studies
    Lei Chen, Linyi Tang, Hui Xiang, Lijun Jin, Qiye Li, Yang Dong, Wen Wang, Guojie Zhang · 2014 · GigaScience
  90. Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases
    Johnny H. Hu, Kevin M Davis, David R. Liu · 2016 · Cell chemical biology
  91. Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing
    Arnold Park, Patrick W.-P. Hong, Sohui T. Won, Patricia A. Thibault, Frédéric Vigant, Kasopefoluwa Y. Oguntuyo, Justin D. Taft, Benhur Lee · 2016 · Molecular Therapy — Methods & Clinical Development
  92. The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches
    B. Motta, P. Pramstaller, A. Hicks, A. Rossini · 2017 · Stem Cells International
  93. Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout
    Yvonne Knopp, Franziska K. Geis, Dirk Heckl, Stefan Horn, Thomas Neumann, Johannes Kuehle, Janine Meyer, Boris Fehse, Christopher Baum, Michael Alexander Morgan et al. · 2018 · Molecular Therapy — Nucleic Acids
  94. Stem Cells on the Brain: Modeling Neurodevelopmental and Neurodegenerative Diseases Using Human Induced Pluripotent Stem Cells
    Priya Srikanth, Tracy L. Young‐Pearse · 2014 · Journal of Neurogenetics
  95. CRISPR-based gene expression control for synthetic gene circuits
    Javier Santos‐Moreno, Yolanda Schaerli · 2020 · Biochemical Society Transactions
  96. The Role of Recombinant AAV in Precise Genome Editing
    Swati Bijlani, Ka Ming Pang, Venkatesh Sivanandam, Amanpreet Singh, Saswati Chatterjee · 2022 · Frontiers in Genome Editing
  97. The application of genome editing in studying hearing loss
    Bing Zou, Rahul Mittal, M’hamed Grati, Zhongmin Lu, Yilai Shu, Yong Tao, Youg Feng, Dinghua Xie, Weijia Kong, Shiming Yang et al. · 2015 · Hearing Research
  98. Harnessing “A Billion Years of Experimentation”: The Ongoing Exploration and Exploitation of CRISPR–Cas Immune Systems
    Sanne E. Klompe, Samuel H. Sternberg · 2018 · The CRISPR Journal
  99. CRISPR-Based Tools in Immunity
    Dimitre R. Simeonov, Alexander Marson · 2019 · Annual Review of Immunology
  100. Molecular mechanisms, off‐target activities, and clinical potentials of genome editing systems
    Nannan Zheng, Liyang Li, Xiangdong Wang · 2020 · Clinical and Translational Medicine