The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes
Open accessAbstract
We compared the ability of short hairpin RNA (shRNA) and CRISPR/Cas9 screens to identify essential genes in the human chronic myelogenous leukemia cell line K562. We found that the precision of the two libraries in detecting essential genes was similar and that combining data from both screens improved performance. Notably, results from the two screens showed little correlation, which can be partially explained by the identification of distinct essential biological processes with each technology.
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Cites
An integrated encyclopedia of DNA elements in the human genome
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Genome-scale CRISPR-Cas9 knockout screening in human cells
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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
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Expression profiling reveals off-target gene regulation by RNAi
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Cited by
Marschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2019) · doi:10.1101/722827 · Cited by 1,414
Self-citationMarschallinger, J., Iram, T., Zardeneta, M., Lee, S. E., Lehallier, B., Haney, M. S., Pluvinage, J. V., Mathur, V., Hahn, O., Morgens, D. W., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0566-1 · Cited by 1,384
Self-citationPrioritization of cancer therapeutic targets using CRISPR–Cas9 screens
Behan, F. M., Iorio, F., Picco, G., Gonçalves, E., Beaver, C. M., Migliardi, G., Santos, R., Rao, Y., Sassi, F., Pinnelli, M., et al. (2019) · Nature · doi:10.1038/s41586-019-1103-9 · Cited by 1,338
Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening
Joung, J., Konermann, S., Gootenberg, J. S., Abudayyeh, O. O., Platt, R. J., Brigham, M. D., Sanjana, N. E., & Zhang, F. (2017) · Nature Protocols · doi:10.1038/nprot.2017.016 · Cited by 1,243
Interferon-Stimulated Genes: What Do They All Do?
Schoggins, J. W. (2019) · Annual Review of Virology · doi:10.1146/annurev-virology-092818-015756 · Cited by 1,036
Metadata
- Authors
- Morgens, D. W., Deans, R. M., Li, A., & Bassik, M. C.
- Venue
- Nature Biotechnology
- Published
- 2016-05-09
- Volume
- 34
- Issue
- 6
- Pages
- 634-636
- ISSN
- 0733-222X (ISSN-L)
- 1087-0156
- 1546-1696
- OpenAlex
- W2346643793
- Cited by
- 401
- References
- 41
- FWCI
- 22.57
- Type
- journal article
- Language
- en
- Open access
- green
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