Cited by 279CRISPR and Genetic EngineeringGenetically Modified Organisms ResearchTransgenic Plants and Applications

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

With a free pass, CRISPR-edited plants reach market in record time

Waltz, Emily·2018·Nature Biotechnology

DOI 10.1038/nbt0118-6b

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1038/nbt0118-6b

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Gene-edited CRISPR mushroom escapes US regulation
Waltz, E. (2016) · Nature · doi:10.1038/nature.2016.19754 · Cited by 549
Nonbrowning GM apple cleared for market
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt0415-326c · Cited by 87
Tiptoeing around transgenics
Waltz, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2143 · Cited by 84
A face-lift for biotech rules begins
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt1215-1221 · Cited by 14
Scotts' GM grass grows free from regulation
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt0315-223 · Cited by 4

Show all 5 references

Research works printed but not linked: 1

2015, Nat. Biotechnol., 33, 326

Sorted by citations

Items 101–200 of 278

Integrating CRISPR/Cas systems with programmable DNA nanostructures for delivery and beyond
Piskunen, P., Latham, R., West, C. E., Castronovo, M., & Linko, V. (2022) · iScience · doi:10.1016/j.isci.2022.104389 · Cited by 23
“To-date, therehavebeenconsiderableadvances in theapplicationof this technology, including agricultural CRISPR/Cas-edited products brought tomarket (Waltz, 2018, 2022), bacterialmetabolic engineering (Liu et al., 2020b) and, inmedicine, gene editing-based approaches are already being used to develop…”
CRISPR-Cas9 Application in Canadian Public and Private Plant Breeding
Gleim, S. W., Lubieniechi, S., & Smyth, S. J. (2020) · The CRISPR Journal · doi:10.1089/crispr.2019.0061 · Cited by 23
“16 Several other plant products produced with CRISPR have be conﬁrmed outside of USDA authority, including anti-browning mushrooms, drought-and salt-tolerant soybeans, and waxy corn.”
Foreign DNA detection by high-throughput sequencing to regulate genome-edited agricultural products
Itoh, T., Onuki, R., Tsuda, M., Oshima, M., Endo, M., Sakai, H., Tanaka, T., Ohsawa, R., & Tabei, Y. (2020) · Scientific Reports · doi:10.1038/s41598-020-61949-5 · Cited by 23
Fruit crops improvement using CRISPR/Cas9 system
Kaur, N., Awasthi, P., & Tiwari, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818140-9.00012-x · Cited by 22
Development and prospect of gene-edited fruits and vegetables
Zhang, S., & Zhu, H. (2023) · Food Quality and Safety · doi:10.1093/fqsafe/fyad045 · Cited by 22
Genome-Editing Products Line up for the Market: Will Europe Harvest the Benefits from Science and Innovation?
Polidoros, A. N., Nianiou‐Obeidat, I., Τσακιρπάλογλου, Ν., Petrou, N., Deligiannidou, E., & Makri, N.-M. (2024) · Genes · doi:10.3390/genes15081014 · Cited by 21
“Similarly, targeted disruptions of soybean genes involved in abiotic stress responses have resulted in increasing its tolerance to drought and salinity, making it more adaptable to climate change [61].”
Background
Nanotechnology and CRISPR/Cas9 system for sustainable agriculture
Khanna, K., Ohri, P., & Bhardwaj, R. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-26482-8 · Cited by 22
“…rule defining sustainable, ecological, consistent, uniform, responsible and efficient was recently introduced by the Department of Agriculture in 2020, which updated and streamlined various regulatory practices for sustainable and rapid innovations in genetic engineering of crops (Waltz 2018).”
Background
Modification of Fatty Acid Profile and Oil Contents Using Gene Editing in Oilseed Crops for a Changing Climate
Rauf, S., Fatima, S., & Ortiz, R. O. (2023) · GM crops & food · doi:10.1080/21645698.2023.2243041 · Cited by 20
“9,12 Figure 2 shows the process for gene editing using CRISP/ Cas9-mediated target gene mutation.”
Method
Improvement of Crop’s Stress Tolerance by Gene Editing CRISPR/CAS9 System
Singh, A. K., Roychowdhury, R., Singh, T., Wang, W., Yadav, D., Kumar, A., Modi, A. R., Rai, A. C., Ghughe, S., Kumar, A., et al. (2020) · Springer eBooks · doi:10.1007/978-3-030-45669-6_24 · Cited by 19
CRISPR genome engineering for retinal diseases
Kantor, A., McClements, M. E., Peddle, C. F., Fry, L. E., Salman, A., Cehajic‐Kapetanovic, J., Xue, K., & MacLaren, R. E. (2021) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2021.01.024 · Cited by 19
Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications
Clauer, P. R., Nou, A., Toth, T., Yu, Q., Chemla, Y., Boo, A., Yoon, K. S., & Voigt, C. A. (2026) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00687 · Cited by 21
Next-generation technologies for iron and zinc biofortification and bioavailability in cereal grains
Ibrahim, S., Saleem, B., Naeem, M. K., Arain, S. M., & Khan, M. R. (2021) · Australian Journal of Agricultural Research · doi:10.1071/cp20498 · Cited by 20
“Further, USDA stated that crops edited by CRISPR/Cas9 can be cultivated and commercialised without regulatory monitoring (Waltz 2018).”
Background
CRISPR/CAS9: A new paradigm for crop improvement revolutionizing agriculture
Kafle, S. (2022) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2022.100484 · Cited by 18
Benefit–Cost Analysis of Increased Funding for Agricultural Research and Development in the Global South
Rosegrant, M. W., Wong, B. A., Sulser, T. B., Dubosse, N., & Lybbert, T. J. (2023) · Journal of Benefit-Cost Analysis · doi:10.1017/bca.2023.27 · Cited by 18
“In addition, more effective regulatory and intellectual property rights systems that reduce the lag times from discovery to deployment of new varieties can also improve the efficiency of research, particularly in light of advanced breeding technologies (Waltz, 2018).”
Background
Gene editing for tolerance to temperature stress in plants: A review
Chakraborty, A., Choudhury, S., Kar, S. R., Deb, P., & Wylie, S. J. (2023) · Plant Gene · doi:10.1016/j.plgene.2023.100439 · Cited by 20
CRISPR/Cas9: an advanced platform for root and tuber crops improvement
Divya, K., Thangaraj, M., & Radhika, N. K. (2024) · Frontiers in Genome Editing · doi:10.3389/fgeed.2023.1242510 · Cited by 20
“The ef ﬁ ciency of CRISPR/ Cas9-induced knockout of the PPO to yield non-browning mushrooms and apples is evidenced in different studies (Halterman et al., 2016; Nishitani et al., 2016; Waltz, 2016; Waltz, 2018).”
Background
Updates and Applications of CRISPR/Cas Technology in Plants
Vidya, N., & Arun, M. (2023) · Journal of Plant Biology · doi:10.1007/s12374-023-09383-8 · Cited by 18
CRISPR-Cas Mediated Genome Editing: A Paradigm Shift towards Sustainable Agriculture and Biotechnology
Rehman, R. S., Zafar, S. A., Ali, M., Pasha, A. N., Naveed, M. S., Waseem, M., Ahmad, M., & Raza, A. (2022) · Asian Plant Research Journal · doi:10.9734/aprj/2022/v9i130197 · Cited by 16
“The United States Department of Agriculture has identified over 100 plant varieties generated by genetic modifications as not regulated, enabling commercial cultivation in the United States of America [69].”
Background
Woody Plant Transformation: Current Status, Challenges, and Future Perspectives
Maharjan, B., Islam, M. T., Muzaffar, A., Tschaplinski, T. J., Tuskan, G. A., Chen, J., & Yang, X. (2025) · Plants · doi:10.3390/plants14223420 · Cited by 21
“There are some edited crops that have already been approved for sale like the gene-edited CRISPR mushroom developed by [147] and Camelina sativa , or false flax, with enhanced omega-3 oil developed by [148].”
Approaches, Applicability, and Challenges for Development of Climate-Smart Soybean
Chaudhary, J., Shivaraj, S. M., Khatri, P., Ye, H., Zhou, L., Klepadlo, M., Dhakate, P., Kumawat, G., Patil, G., Sonah, H., et al. (2019) · Springer eBooks · doi:10.1007/978-3-319-93536-2_1 · Cited by 15
Metabolic engineering to increase crop yield: From concept to execution
Skraly, F. A., Ambavaram, M. M. R., Peoples, O. P., & Snell, K. D. (2018) · Plant Science · doi:10.1016/j.plantsci.2018.03.011 · Cited by 15
Socioeconomic Impact of Genome Editing on Agricultural Value Chains: The Case of Fungal-Resistant and Coeliac-Safe Wheat
Maaß, O., Consmüller, N., & Kehlenbeck, H. (2019) · Sustainability · doi:10.3390/su11226421 · Cited by 19
Rollout of high-priced cell and gene therapies forces payer rethink
Senior, M. (2018) · Nature Biotechnology · doi:10.1038/nbt0418-291a · Cited by 14
Light Dynamics of the Retinal‐Disease‐Relevant G90D Bovine Rhodopsin Mutant
Kubatova, N., Mao, J., Eckert, C. E., Saxena, K., Gande, S. L., Wachtveitl, J., Glaubitz, C., & Schwalbe, H. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202003671 · Cited by 12
Emerging Trends in Transgenic Technology for Phytoremediation of Toxic Metals and Metalloids
Ahmed, I., Sebastain, A., Prasad, M. N. V., & Kirti, P. B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814389-6.00003-1 · Cited by 12
Will gene-edited and other GM crops fail sustainable food systems?
Wilson, A. K. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816410-5.00013-x · Cited by 14
Estimating worldwide benefits from improved bananas resistant to Fusarium Wilt Tropical race 4
Silva, F. D. F., Kaplan, S. M., Magdama, F., Potts, M. D., Espinel, R., & Zilberman, D. (2023) · Journal of the Agricultural and Applied Economics Association · doi:10.1002/jaa2.41 · Cited by 12
Perceptions of plant breeding methods–from ‘phenotypic selection’ to ‘genetic modification’ and ‘new breeding technologies’
Caradus, J. R. (2023) · New Zealand Journal of Agricultural Research · doi:10.1080/00288233.2023.2187425 · Cited by 12
Genome Editing and Abiotic Stress Tolerance in Crop Plants
Surabhi, G., Badajena, B., & Sahoo, S. K. (2019) · Springer eBooks · doi:10.1007/978-3-030-21687-0_2 · Cited by 12
CRISPR-Cas Technology: A Genome-Editing Powerhouse for Molecular Plant Breeding
Mohan, C., Satish, L., Muthubharathi, B. C., Selvarajan, D., Easterling, M., & Yau, Y. (2022) · Springer eBooks · doi:10.1007/978-981-16-9001-3_32 · Cited by 13
Precision harvest: path to genetically modified organism-free crops with CRISPR by 2035
Ahmar, S., Zhang, R., Pouramini, P., Janeczko, A., Shafique, M. S., Rapacz, M., Reis, R. S., Zhu, Q., Hensel, G., & Pociecha, E. (2026) · Trends in Plant Science · doi:10.1016/j.tplants.2025.12.014 · Cited by 11
Regulatory framework of CRISPR-edited crops in the United States
Sagawa, C. H. D., Assis, R. D. A. B., & Zaini, P. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18444-4.00004-1 · Cited by 11
Novel biotechnological approaches to produce biological compounds: challenges and opportunities for science communication
Pei, L., & Schmidt, M. R. (2018) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2018.08.012 · Cited by 13
Patents and technology transfer in CRISPR technology
Grobler, L., Suleman, E., & Raj, D. B. T. G. (2021) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2021.01.009 · Cited by 12
Regulation of CRISPR edited food and feed: legislation and future
Ghouri, M. Z., Munawar, N., Aftab, S. O., & Ahmad, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-823903-2.00004-4 · Cited by 11
CRISPR/Cas techniques: a new method for RNA interference in cereals
Fiaz, S., Khan, S. A., Anis, G. B., Gaballah, M. M., & Riaz, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821910-2.00032-1 · Cited by 10
Genetic Engineering in the United States: Regulation of Crops and Their Food Products
Grossman, M. R. (2019) · Springer eBooks · doi:10.1007/978-3-030-17119-3_7 · Cited by 10
Emergent challenges for CRISPR: biosafety, biosecurity, patenting, and regulatory issues
Braddick, D., & Ramarohetra, R. F. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818140-9.00021-0 · Cited by 10
Achieving highly efficient gene transfer to the bladder by increasing the molecular weight of polymer-based nanoparticles
Li, G., He, S., Schätzlein, A. G., Weiss, R. M., Martin, D. T., & Uchegbu, I. F. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.02.007 · Cited by 10
CRISPER/Cas in Plant Natural Product Research: Therapeutics as Anticancer and other Drug Candidates and Recent Patents
Dey, A., & Nandy, S. (2021) · Recent Patents on Anti-Cancer Drug Discovery · doi:10.2174/1574892816666210706155602 · Cited by 10
Rethinking gene-edited crop regulation: advancing a Principle-based framework for modern biotechnology governance
Vengadesen, S., Aziz, M. F. B. A., & Jones, M. G. K. (2025) · GM crops & food · doi:10.1080/21645698.2025.2576734 · Cited by 9
“25 While such advances hold great promise to support sustainable agriculture and global food security, they also raise issues for existing national regulatory frameworks.”
Integrated approach for the molecular characterization of edited plants obtained via Agrobacterium tumefaciens-mediated gene transfer
Costa, L. D., Vinciguerra, D., Giacomelli, L., Salvagnin, U., Piazza, S., Spinella, K., Malnoy, M., Moser, C., & Marchesi, U. (2021) · European Food Research and Technology · doi:10.1007/s00217-021-03881-0 · Cited by 9
“Some genome edited plants, like the Calyxt Soybean with higher oleic acid content, is already cultivated and commercialized in the USA under conventional regulation [1, 2].”
Background
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Associated Proteins (Cas) [CRISPR–Cas]: An Emerging Technique in Plant Disease Detection and Management
Ghosh, S. K., & Chatterjee, T. (2024) · Springer eBooks · doi:10.1007/978-981-99-8529-6_22 · Cited by 10
To become more sustainable organic agriculture needs genome editing technology
Fernandes, P. M. B., Favaratto, L., Fernandes, A. A. R., Vicién, C., Capalbo, D. M. F., & Júnior, F. M. Z. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.912793 · Cited by 9
“The CRISPR-Cas9 technique made gene editing possible with the purpose of inducing important properties in plant development without necessarily introducing an exogenous gene (Waltz 2016a, 2016b; Nishitani et al., 2016; Shi et al., 2017; Waltz 2018; Jansing et al., 2019; Lyzenga et al., 2019; Gramazio et al., 2020; Cai…”
BackgroundMethod
Biotechnological advances in combating Fusarium wilt of banana: from pathogen biology to sustainable disease management
Ali, M. M., Cheng, X., Zhang, J., Zheng, Y., Li, X., & Liu, J. (2025) · Horticultural Plant Journal · doi:10.1016/j.hpj.2025.08.017 · Cited by 8
Biolistic DNA Delivery and Its Applications in Sorghum bicolor
Liu, G., Massel, K., Tabet, B., & Godwin, I. D. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0356-7_10 · Cited by 8
Breeding Finger Millet for Abiotic Stress Tolerance: Strategies and Challenges
Nair, V. D., & Devi, R. (2024) · Springer eBooks · doi:10.1007/978-981-99-7232-6_11 · Cited by 10
Key Applications of CRISPR/Cas for Yield and Nutritional Improvement
Mubarik, M. S., Khan, S. H., & Sajjad, M. (2021) · Springer eBooks · doi:10.1007/978-981-15-7142-8_7 · Cited by 8
Available Toolkits for CRISPR/CAS Genome Editing in Plants
Mikhaylova, E. V., Khusnutdinov, E., Chemeris, A. V., & Кулуев, Б. Р. (2022) · Russian Journal of Plant Physiology · doi:10.1134/s1021443722010137 · Cited by 8
To win at gene therapy, companies pick viruses with production credentials
Sheridan, C. (2019) · Nature Biotechnology · doi:10.1038/nbt0119-5 · Cited by 8
CRISPR and RNA interference: revolutionary tools for extending food shelf life and ensuring safety
Sidhu, A. K., Sharma, M., Shah, P., & Sandhu, S. K. (2025) · Frontiers in Food Science and Technology · doi:10.3389/frfst.2025.1609948 · Cited by 8
“Countries such as the United States and Brazil have comparatively lenient rules, with gene-edited crops that do not contain foreign DNA not categorised as genetically modi ﬁ ed organisms (GMOs) and so exempt from severe regulatory scrutiny (Waltz, 2018).”
Quelles performances pour les animaux de demain ? Objectifs et méthodes de sélection
Roy, P. L., Alain Ducos, A., & Phocas, F. (2019) · INRAE Productions Animales · doi:10.20870/productions-animales.2019.32.2.2466 · Cited by 7
Modern Techniques for Plant Breeding in Ornamentals
Chandler, S. F., & Tribe, D. E. (2022) · Springer eBooks · doi:10.1007/978-981-15-3518-5_19 · Cited by 7
GM Food Regulations in the EU
Schuler, L., Zust, D., Vybiral, D., & Hau, P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-08-100596-5.22609-7 · Cited by 7
CRISPR off-target analysis platforms
Xu, C. L., Ruan, M. Z., Ragi, S. D., & Tsang, S. H. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2651-1_26 · Cited by 6
Recent Advances in CRISPR/Cas9 Technology for Engineering Disease Resistance in Plants
Bhalerao, S., Okoń, S., Rai, M., Jadhav, P., & Prokisch, J. (2025) · Acta Agrobotanica · doi:10.5586/aa/201389 · Cited by 6
Advances in CRISPR/Cas systems for engineering abiotic stress tolerance in plants: mechanisms and future prospects
Farooq, M., Khan, A., Hassan, A., & Shah, M. M. (2026) · Planta · doi:10.1007/s00425-026-04942-y · Cited by 6
Biotechnological Approaches for Enhancing Disease Resistance and Crop Quality in Horticultural Plants
Abas, A., Huded, S., Reddy, K. J., Panigrahi, C. K., Padamini, R., Diwan, S., Tyagi, V., & Saiyad, M. Y. (2024) · PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY · doi:10.56557/pcbmb/2024/v25i9-108829 · Cited by 6
Current status on the modification of the scope for GMO regulation on the gene edited plants with no remnants of inserted foreign DNA fragments
Lee, S.-W. (2019) · Journal of Plant Biotechnology · doi:10.5010/jpb.2019.46.3.137 · Cited by 6
“나머지 3건은 식물 병･해충(plant pest) 또는 유해 잡초(noxious weeds) 인자를 내 포하고 있지 않으므로 규제대상에서 제외하였다(Waltz 2018; OECD 2019).”
Genome Editing and miRNA-Based Approaches in Cereals under Abiotic Stress
Premnath, A., Ramalingam, A. P., Ramasamy, S. P., Karnatam, K. S., & Ramadoss, B. R. (2022) · Springer eBooks · doi:10.1007/978-981-19-5121-3_25 · Cited by 6
Applications of Genome Editing Techniques for the Improvement of Medicinal Plants
Mishra, R., Agarwal, P., & Mohanty, A. (2022) · Springer eBooks · doi:10.1007/978-981-19-5779-6_22 · Cited by 6
Genetically Modified Crops and Crop Species Adapted to Global Warming in Dry Regions
Das, A., Mahanta, M., Pramanik, B., & Purkayastha, S. (2023) · Springer eBooks · doi:10.1007/978-981-19-9159-2_19 · Cited by 6
First edible cottonseed go-ahead
Waltz, E. (2018) · Nature Biotechnology · doi:10.1038/nbt1218-1126 · Cited by 6
Comparing the effects of regulating new genomic techniques on investment decisions in the European Union
Kardung, M., Ambrogio, Y., Cingiz, K., Consmüller, N., Unkel, K., Purnhagen, K. P., & Wesseler, J. (2026) · European Review of Agricultural Economics · doi:10.1093/erae/jbag004 · Cited by 5
Impact of Climate Change on Agricultural Ecosystem
Ayilara, M. S., Fasusi, S. A., Ajakwe, S. O., Akinola, S. A., Ayilara-Adewale, O. A., Ajakaye, A. E., Ayilara, O. A., & Babalola, O. O. (2025) · Springer eBooks · doi:10.1007/978-3-031-71164-0_22-1 · Cited by 5
CRISPR-based pathogenic fungal genome editing for control of infection and disease
Arazoe, T. (2021) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2020.12.016 · Cited by 5
CRISPR-CAS UYGULAMALARI, POTANSİYEL RİSKLER VE YASAL DÜZENLEMELER
TOSUN, Ö. K., & Kesmen, Z. (2022) · Helal ve Etik Araştırmalar Dergisi · doi:10.51973/head.1209563 · Cited by 4
CRISPR/Cas techniques used in plant disease management
Saraswat, P., Singh, D., Singh, A., Mathur, S., Waswani, H., & Ranjan, R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15199-6.00007-5 · Cited by 5
Updates on Global Status of Transgenic and Genome-Edited Crops
Koul, B., Pudhuvai, B., Bhanot, M., & Tiwari, S. (2024) · Springer eBooks · doi:10.1007/978-981-97-3119-0_19 · Cited by 5
Molecular Mechanism of Plant Adaptation and Tolerance to Cold Stress
Gupta, D., Gupta, A., Yadav, K., & Ranjan, R. (2020) · Springer eBooks · doi:10.1007/978-981-15-2172-0_4 · Cited by 5
CHALLENGES TO THE ADOPTION OF MODERN CROP BIOTECHNOLOGY: INSIGHTS FROM INDIAN AND MALAYSIAN GM REGULATORY FRAMEWORKS
SINGH, J. K. D., Jalaluddin, N. S. M., Mishra, N. S., & Harikrishna, J. A. (2020) · Malaysian Applied Biology · doi:10.55230/mabjournal.v49i5.1632 · Cited by 5
Scaling Banana Bacterial Wilt Management Through Single Diseased Stem Removal in the Great Lakes Region
Kikulwe, E., Asindu, M., Ocimati, W., Ajambo, S., Tinzaara, W., Iradukunda, F., & Blomme, G. (2022) · Springer eBooks · doi:10.1007/978-3-030-92022-7_10 · Cited by 5
Achievements, Challenges, and Prospects in the Production of Nontransgenic, Genome-Edited Plants
Miroshnichenko, D. N., Shulga, O. А., Timerbaev, V. R., & Dolgov, S. V. (2019) · Applied Biochemistry and Microbiology · doi:10.1134/s0003683819090047 · Cited by 5
Biotechnological Advancements in Phytoremediation
Chunduri, V., Kapoor, P., Kumari, A., Kumar, A., Sharma, S., Sharma, N., Kaur, S., & Garg, M. (2023) · Wiley eBooks · doi:10.1002/9781119989318.ch11 · Cited by 5
An Analysis of Global Policies and Regulation on Genome Editing in Plants
Kumawat, T., Agarwal, A., Saxena, S., & Arora, S. (2024) · Springer eBooks · doi:10.1007/978-981-99-8529-6_27 · Cited by 4
Identification, charectrization and genetic transformation of lignin and pectin polysaccharides through CRISPR/Cas9 in Nicotiana tobacum
Ahmed, R. I., Ren, A., Alshaya, D. S., Fiaz, S., Kong, Y., Liaqat, S., Ali, N., Saddique, M. A. B., Attia, K. A., & Taga, M. U. H. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01472-2 · Cited by 4
“Genome modified crops can be utilized in breeding programs as they carry the edited DNA with efficient manner than the conventional transgenic crops (Malzahn et al. 2017; Waltz 2018).”
Advancements in CRISPR/Cas technology for generating herbicide tolerant crops: a comprehensive review
Sreekanth, D., Pawar, D. V., Sahadeo, I. K., Kumar, R., Basavaraj, P. S., Mahesh, S., Chethan, C. R., Mangrauthia, S. K., Sondhia, S., Singh, P. K., et al. (2025) · Journal of Plant Biochemistry and Biotechnology · doi:10.1007/s13562-025-00984-7 · Cited by 6
“In the USA, over 100 genome-edited plants, including high-oil camelina and powdery mildew-resistant wheat, have been deemed non-regulated (Waltz 2018).”
The CRISPR Revolution: Unraveling the mysteries of Life’s genetic code
Harsij, Z., Ghafoorzadeh, Z., & Goharian, E. (2023) · Gene · doi:10.1016/j.gene.2023.147870 · Cited by 5
Commercialization of CRISPR-Cas technology: issues and impact
Kharkwal, G. B., Kundu, M. G., Verma, D., & Mishra, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91808-4.00002-x · Cited by 4
Trends and developments in vegetable research In India — A review
Pandey, S., Sagar, V. R., Nagendran, K., Devi, J., Yadav, P. S., & Kujur, S. N. (2024) · Current Horticulture · doi:10.5958/2455-7560.2024.00035.5 · Cited by 4
Nanocarriers in Plant Genetic Engineering
Ogidi, O. I., Okara, E., & Barwant, M. M. (2025) · IGI Global eBooks · doi:10.4018/979-8-3693-9869-2.ch004 · Cited by 4
Contribution of Omics and Systems Biology to Plant Biotechnology
Dalio, R. J. D., Litholdo, C. G., Arena, G., Magalhães, D. M., & Machado, M. A. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-80352-0_10 · Cited by 4
CRISPR/Cas9 for soybean improvement: A review
Kar, S. R., Choudhury, S., & Chakraborty, A. (2022) · Asia-Pacific Journal of Molecular Biology and Biotechnology · doi:10.35118/apjmbb.2022.030.3.05 · Cited by 4
“Moreover, the regulatory evaluation has been lifted for edited drought-tolerant soybean by the US Department of Agriculture (USDA) (Waltz 2018).”
Advances in forest restoration management and technology
Stanturf, J. A., Dumroese, R. K., Elliott, S., Ivetić, V., Khokthong, W., Kleine, M., Lang, M., Löf, M., Madsen, P., Prescott, C. E., et al. (2024) · Oxford University Press eBooks · doi:10.1093/9780197683958.003.0011 · Cited by 7
26. New plant breeding technologies: US Department of Agriculture policy
Grossman, M. R. (2019) · European Institute for Food Law series · doi:10.3920/978-90-8686-885-8_26 · Cited by 4
Vegetable Crop Improvement Using CRISPR/Cas9
Gonzalez, F. F. N. D. C., & Franco, D. D. L. M. (2020) · Concepts and strategies in plant sciences · doi:10.1007/978-3-030-42022-2_6 · Cited by 4
Transduction of gluconeogenic enzymes prolongs cone photoreceptor survival and function in models of retinitis pigmentosaPreprint
Chinchore, Y., Begaj, T., Guillermeir, C., Steinhauser, M. L., Punzo, C., & Cepko, C. L. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/569665 · Cited by 4
Application of Genome Engineering Methods for Quality Improvement in Important Crops
Fiaz, S., Khan, S. A., Anis, G. B., Ali, H., Ali, M., Ali, K., Noor, M. A., Ahmad, S., & Asad, B. A. (2021) · Wiley eBooks · doi:10.1002/9781119672425.ch3 · Cited by 5
Genomic Interventions for Improving Crop Yield and Resilience
Barmukh, R., Thakur, N. R., & Shah, P. (2024) · Advances in plant breeding strategies · doi:10.1007/978-3-031-68586-6_3 · Cited by 3
Comprehensive approaches to design efficient gRNA for SDN1-CRISPR/Cas9 genome editing in wheat
Singh, T., Mamrutha, H. M., Rajender, S., Jaiswal, J. P., Wadhwa, Z., Kumar, R., Singh, O., Ahlawat, O. P., & Tiwari, R. (2025) · Frontiers in Genome Editing · doi:10.3389/fgeed.2025.1579165 · Cited by 4
“Many of their products are under ﬁ eld testing in different countries, and several have been commercially released (Abdul Aziz et al., 2022; Waltz, 2018; Menz et al., 2020; Sprink et al., 2022; Bruetschy, 2019).”
CRISPR and RNAi technology for crop improvements in the developing countries
Hameed, A., & Awais, M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821910-2.00034-5 · Cited by 3
DNA-free genome editing
Gao, H., Ran, Q., Hu, X., & Zhu, Q. (2020) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/tb-2020-0891 · Cited by 2
Looking for Maize Genes Involved in Cold Response: Producing Knockouts for Arabidopsis Homologs of Maize Candidate Genes Using a CRISPR/Cas9 Approach
Hillmann, K. (2019) · Digital Commons - Hamline (Hamline University) · Cited by 3
Genetic Modification of Pest and Beneficial Insects for Pest Management Programs
Hoy, M. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815230-0.00014-5 · Cited by 3
Transgenic horticultural crops for combating abiotic stresses
Tiwari, V., & Charuvi, D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822849-4.00006-1 · Cited by 3
Light Dynamics of the Retinal‐Disease‐Relevant G90D Bovine Rhodopsin Mutant
Kubatova, N., Mao, J., Eckert, C. E., Saxena, K., Gande, S. L., Wachtveitl, J., Glaubitz, C., & Schwalbe, H. (2020) · Angewandte Chemie · doi:10.1002/ange.202003671 · Cited by 3
Regulation of Genetically Modified and Gene-Edited Foods: An Overview
Martin, A. (2022) · Springer eBooks · doi:10.1007/978-981-16-8125-7_23 · Cited by 3
Creating an Improved Diatoxanthin Production Line by Knocking Out CpSRP54 in the zep3 Background in the Marine Diatom Phaeodactylum tricornutum
Volpe, C., Bartošová, Z., Kissen, R., Winge, P., & Nymark, M. (2025) · Marine Drugs · doi:10.3390/md23110419 · Cited by 2
“…since gene-edited organisms without foreign DNA are excluded from GMO regulations in a range of different countries outside of the EU, such as the UK, USA, Brazil, Argentina, Australia, Israel, India, and Japan [63], making commercialization of products from such mutants more accessible [64,65].”
CRISPR-Cas9 editing of agricultural crops and medicinal plants: toward a cornucopia of natural products
Hefferon, K. L., Venkataraman, S., Alok, A., Moiketsi, B. N., Malik, S., Masisi, K., Rantong, G., Kwape, T. E., Gaobotse, G., & Makhzoum, A. B. (2025) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2025.2577956 · Cited by 2
“…are grown elsewhere. in canada and the USA, cRiSPR/cas9-edited crops are excluded from regulatory measures for cultivation and sale (waltz 2016, waltz 2018). in these countries, genome-edited crops are evaluated on an individual basis, irrespective of the tools used for generating these crops…”
Early Plant Development as a Systems-Level Trait: Integrating Omics, Artificial Intelligence, and Emerging Biotechnologies
Al-Sawa’eer, A. S., Al-Samydai, A., Odeh, L., Ahmad, F. H., Obekh, R., Elqader, Y. M. A., Khaleel, A., Alathamneh, A., Gabriele, M., Simone, S. C. D., et al. (2026) · Plants · doi:10.3390/plants15050787 · Cited by 2

Authors: Waltz, E.
Corresponding author: Waltz, Emily
Venue: Nature Biotechnology
Publisher: Springer Science and Business Media LLC
Published: 2018-01
Volume: 36
Issue: 1
Pages: 6-7
ISSN: 0733-222X (ISSN-L)
1087-0156
1546-1696
DOI: 10.1038/nbt0118-6b
OpenAlex: W2783502825
Cited by: 279
References: 5
Citations by year: 2026: 18 · 2025: 21 · 2024: 34 · 2023: 28 · 2022: 35 · 2021: 40 · 2020: 43 · 2019: 38 · 2018: 21
Type: other
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Biotechnology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
Keywords: CRISPR gene editing, regulatory approval, commercialization, medicinal plants, plant biotechnology regulation
MeSH terms: Gene Editing, Genome, Plant, Camellia, Plants, Genetically Modified, CRISPR-Cas Systems

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

With a free pass, CRISPR-edited plants reach market in record time

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks