The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
With a free pass, CRISPR-edited plants reach market in record time
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The false flax (C. sativa) exhibited enhanced omega-3 oil and was commercially released in the USA, showingrecord-breaking market space (Waltz, 2018).”
From Emerging applications of gene editing technologies for the development of climate-resilient crops (2025) · cites this paper as Waltz, 2018
Citations
Cites
Gene-edited CRISPR mushroom escapes US regulation
Waltz, E. (2016) · Nature · doi:10.1038/nature.2016.19754 · Cited by 549
Nonbrowning GM apple cleared for market
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt0415-326c · Cited by 87
Waltz, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2143 · Cited by 84
A face-lift for biotech rules begins
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt1215-1221 · Cited by 14
Scotts' GM grass grows free from regulation
Waltz, E. (2015) · Nature Biotechnology · doi:10.1038/nbt0315-223 · Cited by 4
Research works printed but not linked: 1
- 2015, Nat. Biotechnol., 33, 326
Cited by
Sorted by citations
Items 201–278 of 278
Market introduction of plant varieties and products with gene-edited traits
Lukasiewicz, J. M., & SMULDERS, M. J. M. (2026) · GM crops & food · doi:10.1080/21645698.2026.2684804 · Cited by 2
Lenka, B., Mohanty, P., Singh, P. K., Adhya, T. K., Mohapatra, R. K., & Mishra, S. (2026) · Indian Journal of Microbiology · doi:10.1007/s12088-026-01565-5 · Cited by 2
“Not only limited to lab but being translated to field-scale, CRISPR-engineered crops are considered ‘future crops’; Omega-3 oil-rich CRISPR C . sativa is popular in the US [104].”
Genome Editing Technologies for Plant Improvement: Advances, Applications and Challenges
Kumar, R., Nizampatnam, N. R., Alam, M., Thakur, T. K., & Kumar, A. (2021) · Springer eBooks · doi:10.1007/978-981-16-0831-5_10 · Cited by 2
Genomic Tools for Improving Tomato to Biotic Stress Resistance
Amoroso, C. G., Panthee, D. R., Andolfo, G., Ramìrez, F. P., & Ercolano, M. R. (2022) · Springer eBooks · doi:10.1007/978-3-030-97785-6_1 · Cited by 2
CRISPR: the Janus god of modern science
Khare, P., Mandal, S., Verma, A. K., Parashar, D., Jadhav, K., & Gupta, S. K. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91808-4.00006-7 · Cited by 2
Regulations of genome edited plants: notes from editors
Abd-Elsalam, K. A., & Ahmad, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18444-4.00007-7 · Cited by 2
HARNESSING POTENTIAL OF PLANT BREEDING STRATEGIES FOR CLIMATE SMART AGRICULTURE
(2023) · Trends in Biotechnology and Plant Sciences · doi:10.62460/tbps/2023.002 · Cited by 3
CRISPR-Cas and Its Applications in Food Production
Rai, N., Singh, N. A., Goyal, J., Upadhayay, P., & Jain, V. (2024) · Springer eBooks · doi:10.1007/978-981-99-8529-6_13 · Cited by 2
Commercialization of CRISPR-edited crops: Opportunities and challenges
Saxena, S., Sushmita, L. C., Babu, Y. M., Chavan, D. D., Venu, E., Mandal, S., Hurrah, I. M., Mohture, V. M., & Mishra, T. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13229-2.00031-4 · Cited by 4
CRISPR-Cas9 genome editing of crops: Food and nutritional security
Krishnan, R. R., Sivakumar, B., Jagannath, N., Rao, N. R., Suresh, N., Nagella, P., Al-Khayri, J. M., & Jain, S. M. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13229-2.00024-7 · Cited by 2
CRISPR applications in medicinal and aromatic plants
Saha, S. C., Mishra, T., Mandal, S., Prasanth, A., Mohture, V. M., & Mane, A. B. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13229-2.00015-6 · Cited by 2
CRISPER-Based Industrial Crop Improvements
Gohil, S. K., Kumari, A., Prakash, A., Shah, N., Bhutani, S., & Singh, M. (2024) · Interdisciplinary biotechnological advances · doi:10.1007/978-981-97-1003-4_5 · Cited by 2
Approaches to Enhance Abiotic and Biotic Stress Tolerance in Leguminous Crops and Microgreens
Sharma, P., & Kumari, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-75678-8_9 · Cited by 2
Parry, G., & Harrison, C. J. (2018) · New Phytologist · doi:10.1111/nph.15573 · Cited by 2
Kwiatek, M. T., Drozdowska, Z., Kurasiak‐Popowska, D., Noweiska, A., & Nawracała, J. (2021) · Journal of Applied Genetics · doi:10.1007/s13353-020-00600-5 · Cited by 2
“Recently, CRISPR-Cas9 system was harnessed to produce camelina breeding lines with increased oleic acid (Jiang et al. 2017; Morineau et al. 2017), decreased long-chain fatty acids (Ozseyhan et al. 2018), and increased oil content (Waltz 2018).”
BackgroundGenome editing: propelling the next generation of crop improvement
Angelotti-Mendonça, J., Koltun, A., de Oliveira, F. F., & Silva, N. V. E. (2021) · Colloquium Agrariae · doi:10.5747/ca.2021.v17.n4.a451 · Cited by 2
CRISPER/CAS: A potential tool for genomes editing
(2021) · Biomedical Letters · doi:10.47262//bl/7.2.20210711 · Cited by 2
“These SSNs can precisely cut DNA at a specific place, and the breaks are repaired by Non-Homologous End Joining (NHEJ) or Homology Directed Repair (HDR), resulting in insertion/deletion or substitution changes in target regions, respectively [3, 4] (Fig.”
BackgroundGenome Editing and CRISPR-Cas Technology for Enhancing Abiotic Stress Tolerance in Cereals
Chowdhury, N., Das, D., Sarki, Y. N., Sharma, M., Singha, D. L., & Chikkaputtaiah, C. (2022) · Springer eBooks · doi:10.1007/978-981-19-0140-9_11 · Cited by 2
Genomic Region Analysis and Genome Editing for Grain Quality Improvement in Cereals
Jangra, S., Priti, P., Chaudhary, V., Mishra, A., Yadav, R. C., & Yadav, N. R. (2022) · Springer eBooks · doi:10.1007/978-3-030-96925-7_14 · Cited by 2
Genome Editing: Mechanism and Utilization in Plant Breeding
Awan, M. J. A., Anjum, N., Pervaiz, K., Ijaz, M. U., Khan, M. Z., Amin, I. U., & Mansoor, S. (2023) · Springer eBooks · doi:10.1007/978-3-031-28146-4_16 · Cited by 2
Current progress and future needs of genetically engineered crop plants
Hull, R., Head, G., & Tzotzos, G. T. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818564-3.00003-2 · Cited by 2
Behera, L., Samal, K. C., Parmeswaran, C., Agrawal, P. K., Achary, V. M. M., Dash, M., Dwibedi, S. K., Bhol, R. K., Kherawat, B. S., Chung, S.-M., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3598516/v1 · Cited by 2
Consumer Evaluation of Novel Plant-Breeding Technologies: A Decision-Focused Research Agenda
Baum, C. M., Ladendorf, J. E., Bröring, S., & Steur, H. D. (2023) · Concepts and strategies in plant sciences · doi:10.1007/978-3-031-10721-4_5 · Cited by 1
Sirohi, U., Shruti, Yadav, M. K., & Kumar, M. (2025) · Discover Plants. · doi:10.1007/s44372-025-00101-x · Cited by 1
“Department of Agriculture (USDA) successfully edited the gene for the mushroom using the CRISPR-Cas9 system in 2016 [128].”
Application of Novel Breeding Methods to Achieve Rapid Genetic Gain in Oilseed Crops
Prasad, A. V. S. D. (2025) · Springer eBooks · doi:10.1007/978-981-97-7744-0_7 · Cited by 1
Varghese, R., Pachamuthu, K., Manickavasagam, M., Muthukaliannan, G. K., & Ramamoorthy, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-43920-9.00002-6 · Cited by 1
Plant Disease Resistance through CRISPR-Cas Genome Editing: Opportunities and Challenges
Hia, F. T., Kayess, M. O., & Islam, T. (2025) · CABI biotechnology series. · doi:10.1079/9781800627307.0024 · Cited by 1
Harnessing Nanotechnology for Enhanced CRISPR-Cas Plant Genome Editing
Shende, H., & Patil, R. (2025) · Springer eBooks · doi:10.1007/978-3-031-97544-8_11 · Cited by 1
CRISPR/Cas system and AI tools for effective gene editing in vegetable crops: a systematic review
Kumar, M., Chaudhary, V., Chaudhary, V., Kumar, R., Sirohi, U., Singh, R., Singh, D., & Teotia, S. (2026) · Discover Applied Sciences · doi:10.1007/s42452-026-08305-w · Cited by 1
Wahyuni, F. D., Fathoni, A., Sukma, D., Ardie, S. W., Zainuddin, I. M., Qi, B., & Sudarsono, S. (2026) · Current Research in Biotechnology · doi:10.1016/j.crbiot.2026.100384 · Cited by 1
Genetic modifications for disease resistance in crops
Ramesh, S., Mangrauthia, S. K., & Praveen, S. (2021) · doi:10.1071/9781486310913.bk07858_ch18 · Cited by 1
Machine Learning and Gene Editing at the Helm of a Societal Evolution
Zakaria, S., Marler, T., Cabling, M., Genc, S., Honich, A., Virdee, M., & Stockwell, S. (2023) · Rand health quarterly · doi:10.7249/rhq-11-02-05 · Cited by 1
Implementing Genome Editing in Barley Breeding
Jakobson, L., Öney-Birol, S., & Timofejeva, L. (2023) · Springer eBooks · doi:10.1007/978-3-031-46150-7_10 · Cited by 1
CRISPR-Cas: A History of Discovery and Innovation
Kumar, A., Yau, Y., & Kumar, V. R. (2024) · Springer eBooks · doi:10.1007/978-981-99-8529-6_1 · Cited by 1
CRISPR vegetables: Challenges and opportunities
Mandal, S., Hurrah, I. M., Khuntia, R. P., Saha, S. C., Sahoo, R. K., Mane, A. B., & Prasanth, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13229-2.00027-2 · Cited by 1
Behera, L., Samal, K. C., Parmeswaran, C., Agrawal, P. K., Achary, V. M. M., Dash, M., Dwibedi, S. K., Bhol, R. K., Kherawat, B. S., Chung, S.-M., et al. (2024) · Cereal Research Communications · doi:10.1007/s42976-024-00507-5 · Cited by 1
“Notably, plant varieties developed through CRISPR/Cas9 technology can now be introduced to the market in the USA without undergoing extensive regulatory monitoring (Waltz 2018).”
Genome engineering in maize using CRISPR/CAS9 system
Rafique, K., Gul, A., Ahmad, N., & Mushtaq, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-26614-0.00002-3 · Cited by 1
Revolutionary Genome Editing Tools for Crop Improvement
Saha, D., Dey, P., Sharma, A., & Parida, S. (2020) · International Journal of Current Microbiology and Applied Sciences · doi:10.20546/ijcmas.2020.907.252 · Cited by 1
Gen Transfer Teknolojisi ve Yağ asidi Kompozisyonlarına Katkısı- CRSPR/Cas Teknolojisi
Eren, B. (2021) · European Journal of Science and Technology · doi:10.31590/ejosat.853850 · Cited by 1
Accelerated Breeding for Brassica Crops
Ferrie, A. M. R., & Polowick, P. L. (2022) · Springer eBooks · doi:10.1007/978-3-030-81107-5_5 · Cited by 1
Nutritional Genomics - An Overview of CRISPR/Cas9 Genome Editing System on Nutraceuticals
Rudrabhatla, S. V. (2022) · Current Trends On Biotechnology & Microbiology Open Access Publishers · doi:10.32474/ctbm.2022.02.000145 · Cited by 1
CRISPR/Cas9: An evolutionary approach towards crops amelioration
Kapil, J., Fartyal, M., & Mathur, N. (2023) · LS International Journal of Life Sciences · doi:10.5958/2319-1198.2023.00004.0 · Cited by 1
A “CRISPY” tale on microalgal genome editing: featuring Nannochloropsis oceanica IMET1
Naduthodi, M. I. S. (2021) · doi:10.18174/555308 · Cited by 1
Synthetic biology tools for the study of relevant factors in the control of transgene expression
González, A. P. (2018) · UPM Digital Archive (Technical University of Madrid) · doi:10.20868/upm.thesis.52923
Synthetic Gene Circuits in Intestinal Bacteria: Biosensors and Pulse Counters
Naydich, A. D. (2019) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Cocoa pollination as a potential yield driver under changing management and climate
Toledo‐Hernández, M. (2020) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-8167
Genome Engineering Strategies for Quality Improvement in Tomato
Wang, T., Zhang, H., & Zhu, H. (2021) · Wiley eBooks · doi:10.1002/9781119672425.ch16
Genome editing and RNA interference technologies in plants
Tamang, T. M., Kakeshpour, T., Hu, Y., Peng, Z., & Wu, Q. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821120-5.00001-8
CRISPR-based genome editing: Catching impossibles for citrus improvements
Jagannadham, P. T. K., & Anbalagan, T. (2021) · International Journal of Agricultural and Applied Sciences · doi:10.52804/ijaas2021.212
“The United States Department of Agriculture (USDA) has already stated that CRISPR/Cas9 edited crops could be cultivated and sold free from any regulatory monitoring (Waltz, 2018), removing all apprehensions among public minds of any such reservation.”
BackgroundModern Techniques for Plant Breeding in Ornamentals
Chandler, S., & Tribe, D. E. (2021) · Springer eBooks · doi:10.1007/978-981-15-1554-5_19-1
Genomic Designing of Climate Smart TurmericPreprint
Shankar, A. (2021) · Preprints.org · doi:10.20944/preprints202111.0394.v1
Recent Progress on Genetic Modification in Floriculture
Ahn, C. H., Park, P. H., Park, P. M., An, H. R., Ramya, M., & Lee, S. Y. (2019) · Flower Research Journal · doi:10.11623/frj.2019.27.4.03
Biotechnological applications in fresh citrus fruit
Ladaniya, M. S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-99306-7.00018-9
Accomplishments in vegetable crop improvement through CRISPR/CAS9 gene editing system
Jyothsna, J., & Luthra, S. (2022) · Journal of Pharmacognosy and Phytochemistry · doi:10.22271/phyto.2022.v11.i4c.14461
Thakur, K., Salaria, N., Singh, B., Bhardwaj, V., Kukreja, S., & Goutam, U. K. (2023) · Plant Science Today · doi:10.14719/pst.2145
Edytowanie genomów roślin uprawnych. Minimum faktów, bez mitów
Orczyk, W. (2019) · Nauka · doi:10.24425/nauka.2019.129255
Kusjiarsih, R. P., Adinugraha, H. H., & Kathryn, M. (2023) · Sharia Oikonomia Law Journal · doi:10.55849/solj.v1i3.190
CRISPRized fruit, vegetable, and ornamental crops: A note from editors
Abd-Elsalam, K. A., Ahmed, A., & Munir, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13229-2.00005-3
Geneedited plants: achievements and prospects (review)
Волкова, Н. Е. (2024) · Plant varieties studying and protection · doi:10.21498/2518-1017.20.1.2024.300137
Bioengineering of Cannabis Plants from Lab to the Field: Challenges and Opportunities
Sayed, F., & Eisenreich, W. (2024) · Concepts and strategies in plant sciences · doi:10.1007/978-981-97-0176-6_24
Gavrilov, N. S., Ignatyeva, N. V., Medvedeva, E. V., & Timashev, P. S. (2024) · Genes and Cells · doi:10.17816/gc633492
Agro-Biotechnology: A Rescue Against World Hunger
Rafiqui, A. R., Mir, M. R., Khan, I., Sharma, R. K., Ganie, A. H., & Ayoub, O. B. (2024) · Springer eBooks · doi:10.1007/978-981-97-5177-8_24
Edición de Genes y CRISPR-Cas: Aplicaciones, Avances y Desafíos: Genes y CRISPR
Elizondo‐Luévano, J. H., Sotelo, L. A. G., Paredes, I. C., de Dios-Romero, V., Villanueva-Terán, C., & Kačániová, M. (2024) · doi:10.29105/agricolis.v1i2.11
Genetically engineered crops for climate resilient agriculture
Rajput, S., Johar, P., & Salgotra, R. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-38325-0.00005-8
Tamizi, A. A., Zainal‐Abidin, R., Md-Yusof, A. A., Mohd-Zim, N. A., Salleh, M. S., Azmi, N. S. A., Zainuddin, Z., Harun, S., Sekeli, R., & Samsulrizal, N. H. (2025) · Malaysian Applied Biology · doi:10.55230/mabjournal.v54i4.3226
“For example, CRISPR-edited mushrooms ( Agaricus bisporus ) and false flax ( Camelina sativa ) have been exempted from biosafety regulations by the US government (Waltz, 2016; Waltz, 2018; Spök et al., 2022).”
Zaidi, S. S., Mahas, A., Vanderschuren, H., & Mahfouz, M. M. (2020) · Figshare · doi:10.6084/m9.figshare.13310938
Nano-innovations for Enhancing Climate Resilience in Millets
Khedr, E. H., Khedr, N., Al‐Dossary, O., & Al-Khayri, J. M. (2026) · Sustainability Sciences in Asia and Africa · doi:10.1007/978-981-95-2754-0_11
Molina, A. N. R. (2026) · Actualidad Jurídica Ambiental · doi:10.56398/ajacieda.00458
Epifanio, L. E. S. (2026) · Actualidad Jurídica Ambiental · doi:10.56398/ajacieda.00459
Genome editing approaches using CRISPR/Cas for sustainable management of Fusarium wilt in crops
Sihag, A., Raj, S. N., Manju, K. G., Sanjana, Lakshmi, S., Prasad, M. N. N., Kotian, S. S., Shetty, S. S., Lakshmi, N. V., Ashok, P., et al. (2026) · Current Plant Biology · doi:10.1016/j.cpb.2026.100633
Dutt, A., Keithellakpam, A., Laskar, A., Kachari, A., Chikkaputtaiah, C., & Saikia, B. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44994-9.00011-0
DE–GE: Synergizing directed evolution and gene editing for precision crop improvement
Zhao, B., Zhou, M., Ren, W., Wang, Y., Liu, X., Li, H., Wang, R., Zhao, J., & Liu, Y. (2026) · The Crop Journal · doi:10.1016/j.cj.2026.07.017
Angon, P. B., Mondal, S., Roy, A. R., Das, A., Tithi, F. Y., Basak, A. R., Pallob, A. T., Chauhan, S., Sagar, J. F., Khan, M. S. U., et al. (2026) · Frontiers in Plant Physiology · doi:10.3389/fphgy.2026.1900397 · Cited by 1
AI and CRISPR: Biosafety, governance, and public perception of gene-edited organisms
Epifanio, L. E. S., Larrabe, J. U., & López, I. F. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44079-3.00016-4
Audu, I. G., Samuel, S., & Asaga, P. M. (2026) · Current Plant Biology · doi:10.1016/j.cpb.2026.100674
Metadata
- Authors
- Waltz, E.
- Corresponding author
- Waltz, Emily
- Venue
- Nature Biotechnology
- Published
- 2018-01
- Volume
- 36
- Issue
- 1
- Pages
- 6-7
- ISSN
- 0733-222X (ISSN-L)
- 1087-0156
- 1546-1696
- OpenAlex
- W2783502825
- Cited by
- 279
- References
- 5
- Citations by year
- 2026: 18 · 2025: 21 · 2024: 34 · 2023: 28 · 2022: 35 · 2021: 40 · 2020: 43 · 2019: 38 · 2018: 21
- Type
- other
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
- Keywords
- CRISPR gene editing, regulatory approval, commercialization, medicinal plants, plant biotechnology regulation
- MeSH terms
- Gene Editing, Genome, Plant, Camellia, Plants, Genetically Modified, CRISPR-Cas Systems
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review