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Cited by 494

The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.

Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis

Open access
Jeffries, Thomas W, Grigoriev, Igor V, Grimwood, Jane, Laplaza, José M, Aerts, Andrea, Salamov, Asaf, Schmutz, Jeremy, Lindquist, Erika, Dehal, Paramvir, Shapiro, Harris, Jin, Yong-Su, Passoth, Volkmar, Richardson, Paul M·2007·Nature Biotechnology

Abstract

Xylose is a major constituent of plant lignocellulose, and its fermentation is important for the bioconversion of plant biomass to fuels and chemicals. Pichia stipitis is a well-studied, native xylose-fermenting yeast. The mechanism and regulation of xylose metabolism in P. stipitis have been characterized and genes from P. stipitis have been used to engineer xylose metabolism in Saccharomyces cerevisiae. We have sequenced and assembled the complete genome of P. stipitis. The sequence data have revealed unusual aspects of genome organization, numerous genes for bioconversion, a preliminary insight into regulation of central metabolic pathways and several examples of colocalized genes with related functions. The genome sequence provides insight into how P. stipitis regulates its redox balance while very efficiently fermenting xylose under microaerobic conditions.

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Crossref · 10.1038/nbt1290

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Metadata

Authors
Jeffries, T. W., Grigoriev, I. V., Grimwood, J., Laplaza, J. M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y.-S., Passoth, V., & Richardson, P. M.
Venue
Nature Biotechnology
Published
2007-03
Volume
25
Issue
3
Pages
319-326
ISSN
  • 0733-222X (ISSN-L)
  • 1087-0156
  • 1546-1696
OpenAlex
W1970871100
Cited by
494
References
61
FWCI
11.97
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. https://app.cochat.ai/papers/10.1038/nbt1290
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Jeffries, T. W., Grigoriev, I. V., Grimwood, J., Laplaza, J. M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y.-S., Passoth, V., & Richardson, P. M. (2007). Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nature Biotechnology. https://doi.org/10.1038/nbt1290

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.