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Investigation of PP2A and Its Endogenous Inhibitors in Neuroblastoma Cell Survival and Tumor Growth

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Altering MYC phosphorylation in the epidermis increases the stem cell population and contributes to the development, progression, and metastasis of squamous cell carcinoma

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Defeating MYC with drug combinations or dual-targeting drugs

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NSD3S stabilizes MYC through hindering its interaction with FBXW7

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CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms

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The Prolyl Isomerase Pin1 Modulates Development of CD8+ cDC in Mice

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Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation

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Calcineurin-mediated dephosphorylation enhances the stability and transactivation of c-Myc

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Pim Kinase Inhibitors Increase Gilteritinib Cytotoxicity in FLT3-ITD Acute Myeloid Leukemia Through GSK-3β Activation and c-Myc and Mcl-1 Proteasomal Degradation

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MYC Promotes Tyrosine Kinase Inhibitor Resistance in ROS1 -Fusion-Positive Lung Cancer

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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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Prolyl Isomerase Pin1 Regulates Transcription Factor LSF (TFCP2) by Facilitating Dephosphorylation at Two Serine-Proline Motifs

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Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2

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Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway

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DNA-based Animal Models of Human Disease: from Genotype to Phenotype

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Pin1-catalyzed conformational regulation after phosphorylation: A distinct checkpoint in cell signaling and drug discovery

Lu, K. P., & Zhou, X. Z. (2024) · Science Signaling · doi:10.1126/scisignal.adi8743 · Cited by 12

EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression

Wolin, A. R., Vincent, M. Y., Hotz, T. J., Purdy, S. C., Rosenbaum, S. R., Hughes, C. J., Hsu, J. Y., Oliphant, M. U. J., Armstrong, B. A., Wessells, V. M., et al. (2023) · Neuro-Oncology · doi:10.1093/neuonc/noad128 · Cited by 11

Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod)

Buddaseth, S., Göttmann, W., Blasczyk, R., & Huyton, T. (2013) · Cancer Biology & Therapy · doi:10.4161/cbt.27307 · Cited by 11

Sphingosine metabolism as a therapeutic target in cutaneous melanoma

Dany, M. (2017) · Translational research · doi:10.1016/j.trsl.2017.04.005 · Cited by 12

The expression of MYC is strongly dependent on the circular PVT1 expression in pure Gleason pattern 4 of prostatic cancer

Umemori, M., Kurata, M., Yamamoto, A., Yamamoto, K., Ishibashi, S., Ikeda, M., Tashiro, K., Kimura, T., Sato, S., Takahashi, H., et al. (2020) · Medical Molecular Morphology · doi:10.1007/s00795-020-00243-9 · Cited by 11

H-Ras induces Nrf2-Pin1 interaction: Implications for breast cancer progression

Saeidi, S., Kim, S., Han, H., Kim, S. H., Zheng, J., Lee, H., Han, W., Noh, D., Na, H., & Surh, Y. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115121 · Cited by 11

RAS and PP2A activities converge on epigenetic gene regulation

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Intranasal Immunization of Lambs with Serine/Threonine Phosphatase 2A against Gastrointestinal Nematodes

Fawzi, E. M., Bustos, T. C., Gómez-Samblás, M., González-González, G., Solano, J., González-Sánchez, M. E., Pablos, L. M. D., Corral, M. J., Cuquerella, M., Osuna, A., et al. (2013) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00336-13 · Cited by 11

Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth

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SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML

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TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation

Shao, F., Wang, R., Li, X., Hu, Y., Zhang, Z., Cai, J., Yang, J.-R., Feng, X., Ren, S., Huang, Z., et al. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07663-4 · Cited by 10

Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene

Jiang, Y., Saga, K., Miyamoto, Y., & Kaneda, Y. (2016) · Oncotarget · doi:10.18632/oncotarget.9105 · Cited by 10

SWATH-MS proteomics of PANC-1 and MIA PaCa-2 pancreatic cancer cells allows identification of drug targets alternative to MEK and PI3K inhibition

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Oncogenic signaling pathways in pancreatic ductal adenocarcinoma

Agrawal, R., & Natarajan, K. N. (2023) · Advances in cancer research · doi:10.1016/bs.acr.2023.02.006 · Cited by 10

MYC function and regulation in flies: how Drosophila has enlightened MYC cancer biology

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Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer

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Relationship between CIP2A expression, and prognosis and MDR-related proteins in patients with advanced gastric cancer.

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Prolyl isomerase Pin1 is required sperm production by promoting mitosis progression of spermatogonial stem cells

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Detection of Post-translational Modifications on MYC

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Recent insights into Protein Phosphatase 2A structure and regulation: the reasons why PP2A is no longer considered as a lazy passive housekeeping enzyme

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PIM1 is a potential therapeutic target for the leukemogenic effects mediated by JAK/STAT pathway mutations in T-ALL/LBL

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The KLF16/MYC feedback loop is a therapeutic target in bladder cancer

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AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration

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TRAF4 is crucial for ST2+ memory Th2 cell expansion in IL-33–driven airway inflammation

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p27kip1 Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation

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Genetic Modeling of Ras‐Induced Human Rhabdomyosarcoma

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Lysine-52 stabilizes the MYC oncoprotein through an SCFFbxw7-independent mechanism

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Coupled intra- and interdomain dynamics support domain cross-talk in Pin1

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Rules for PP2A-controlled phosphosignalling and drug responsesPreprint

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PIN1 Prolyl Isomerase Promotes Initiation and Progression of Bladder Cancer through the SREBP2-Mediated Cholesterol Biosynthesis Pathway

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MYC at the tumor–immune interface: mechanisms of immune escape and immunotherapy resistance

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A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen

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The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squamous cell carcinoma

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Pin1 : une peptidyl-prolylcis-transisomérase multifonctionnelle et une cible anticancéreuse prometteuse

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Dynamic modeling of folliculogenesis signaling pathways in the presence of miRNAs expression

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Cellular localization of CIP 2A determines its prognostic impact in superficial spreading and nodular melanoma

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Cell Growth Inhibition by Okadaic Acid Involves Gut-Enriched Kruppel-like Factor–Mediated Enhanced Expression of c-Myc

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Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivoPreprint

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Smad7-Skp2 complex orchestrates c-Myc stability, impacting on the cytostatic effect of TGF-β

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Biochemical characterization of the Eya and PP2A-B55α interaction

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The expression of cancerous inhibitor protein phosphatase 2A in chronic rhinosinusitis with nasal polyps

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PINning down the c-Myc oncoprotein

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Abstract IA10: Post-translational regulation of MYC's oncogenic activity

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Abstract A89: Targeting the MYC activation and degradation pathway for the treatment of pancreatic cancer

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Switching of the c-Myc protein degradation pathway depending on the PP2A-B55α complex levels

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SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62

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