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The Connection Between Cell Fate and Telomere

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Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells

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Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition

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Arabidopsis thaliana telomeric DNA-binding protein 1 is required for telomere length homeostasis and its Myb-extension domain stabilizes plant telomeric DNA binding

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Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response

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BRCA1 and CtIP promote alternative non‐homologous end‐joining at uncapped telomeres

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RADX prevents genome instability by confining replication fork reversal to stalled forks

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Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6

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Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension

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Shelterin and the replisome: at the intersection of telomere repair and replication

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The fission yeast MRN complex tethers dysfunctional telomeres for NHEJ repair

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Arsenic exposure, genetic susceptibility and leukocyte telomere length in an Italian young adult population

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Multiple Actions of Telomerase Reverse Transcriptase in Cell Death Regulation

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Telomere dysfunction in human diseases: the long and short of it!

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Dual roles of telomere dysfunction in initiation and suppression of tumorigenesis

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Structure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteins

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Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis

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Roles For Nuclear Organization In The Maintenance Of Genome Stability

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How do telomeres and NHEJ coexist?

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PHF11 promotes DSB resection, ATR signaling, and HRPreprint

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TERRA: Long Noncoding RNA at Eukaryotic Telomeres

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Telomeres in toxicology: Occupational health

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Functions of ADP-ribose transferases in the maintenance of telomere integrity

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Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma

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LMP1 and Dynamic Progressive Telomere Dysfunction: A Major Culprit in EBV-Associated Hodgkin’s Lymphoma

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ZNF365 Promotes Stability of Fragile Sites and Telomeres

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Telomere protein RAP1 levels are affected by cellular aging and oxidative stress

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TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends

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SMCHD1 promotes ATM‐dependent DNA damage signaling and repair of uncapped telomeres

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Essential role for the TRF 2 telomere protein in adult skin homeostasis

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Defending the end zone: Studying the players involved in protecting chromosome ends

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Cellular senescence, telomere recombination and maintenance

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Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana

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Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

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Telomere and Subtelomere R-loops and Antigenic Variation in Trypanosomes

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Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery

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Fission yeast Cactin restricts telomere transcription and elongation by controlling Rap1 levels

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Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein–Protein Interaction in the Shelterin Complex

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Mammalian Rap1 widens its impact

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Telomere-associated genes and telomeric lncRNAs are biomarker candidates in lung squamous cell carcinoma (LUSC)

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ATM Inhibition Potentiates Death of Androgen Receptor-inactivated Prostate Cancer Cells with Telomere Dysfunction

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The Leishmania amazonensis TRF (TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres

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Structural and functional association of androgen receptor with telomeres in prostate cancer cells

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53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response

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H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres

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Protection of DNA Ends by Telomeric 3′ G-Tail Sequences

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Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells

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Recruitment of TRF2 to laser-induced DNA damage sites

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The DNA damage response at dysfunctional telomeres, and at interstitial and subtelomeric DNA double-strand breaks

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What telomeres teach us about MS

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Telomeres do the (un)twist: Helicase actions at chromosome termini

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TRF1 uses a noncanonical function of TFIIH to promote telomere replicationPreprint

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Double-stranded telomeric DNA binding proteins: Diversity matters

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SUV39h‐ and A‐type lamin‐dependent telomere nuclear rearrangement

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Telomerase recruitment to telomeres

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TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress

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Association of a Platinum Complex to a G-Quadruplex Ligand Enhances Telomere Disruption

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Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells

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The Caenorhabditis elegans Rad17 Homolog HPR-17 Is Required for Telomere Replication

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High Mobility Group A2 protects cancer cells against telomere dysfunction

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Holding it together: DNA end synapsis during non-homologous end joining

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Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres

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Molecular and chemical genetic approaches to developmental origins of aging and disease in zebrafish

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TRF2 recruits ORC through TRFH domain dimerization

Higa, M., Kushiyama, T., Kurashige, S., Kohmon, D., Enokitani, K., Iwahori, S., Sugimoto, N., Yoshida, K., & Fujita, M. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.11.004 · Cited by 20

Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics

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The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response

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DNA-PK controls Apollo’s access to leading-end telomeres

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Biology of telomeres: importance in etiology of esophageal cancer and as therapeutic target

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Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell‐based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase activation therapies

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Disruption of direct 3D telomere–TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed–Sternberg cells

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Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

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The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function

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Immunodeficiency, radiosensitivity, and the XCIND syndrome

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Are Mouse Telomeres Going to Pot?

Baumann, P. (2006) · Cell · doi:10.1016/j.cell.2006.06.027 · Cited by 19

ssDNA fragments induce cell senescence by telomere uncapping

Tsolou, A., Passos, J. F., Nelson, G., Arai, Y., & Zglinicki, T. V. (2008) · Experimental Gerontology · doi:10.1016/j.exger.2008.08.043 · Cited by 18

Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity

Qin, Q., Qin, J.-L., Meng, T., Yang, G.-A., Wei, Z., Liu, Y., Liang, H., & Chen, Z. (2016) · Scientific Reports · doi:10.1038/srep37644 · Cited by 18

Roles of NOLC1 in cancers and viral infection

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The role of shelterin in maintaining telomere integrity

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Expression of Telomere-Associated Proteins is Interdependent to Stabilize Native Telomere Structure and Telomere Dysfunction by G-Quadruplex Ligand Causes TERRA Upregulation

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Consecutive Formation of G‐Quadruplexes in Human Telomeric‐Overhang DNA: A Protective Capping Structure for Telomere Ends

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Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos

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Telomere dynamics and reproduction

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ZNF524 directly interacts with telomeric DNA and supports telomere integrity

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Telomere maintenance and the DNA damage response: a paradoxical alliance

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Mitosis, double strand break repair, and telomeres: A view from the end

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