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p16INK4a as a Second Effector of the Telomere Damage Pathway

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Homologous recombination and maintenance of genome integrity: Cancer and aging through the prism of human RecQ helicases

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Heart-Breaking Telomeres

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Compartmentalization of telomeres through DNA-scaffolded phase separation

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Telomere Disruption Results in Non-Random Formation of De Novo Dicentric Chromosomes Involving Acrocentric Human Chromosomes

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Discovery of high in vitro and in vivo antitumor activities of organometallic ruthenium( ii )–arene complexes with 5,7-dihalogenated-2-methyl-8-quinolinol

Meng, T., Qin, Q., Chen, Z., Zou, H., Wang, K., & Liang, F. (2019) · Dalton Transactions · doi:10.1039/c9dt00866g · Cited by 71

Human Rap1 modulates TRF2 attraction to telomeric DNA

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Telomere Length Dynamics and the Evolution of Cancer Genome Architecture

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Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV

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53BP1–shieldin-dependent DSB processing in BRCA1-deficient cells requires CST–Polα–primase fill-in synthesis

Mirman, Z., Sasi, N. K., King, A., Chapman, J. R., & de Lange, T. (2022) · Nature Cell Biology · doi:10.1038/s41556-021-00812-9 · Cited by 74

DNA-damage response and repair activities at uncapped telomeres depend on RNF8

Peuscher, M. H., & Jacobs, J. J. L. (2011) · Nature Cell Biology · doi:10.1038/ncb2326 · Cited by 74

Pot1 and cell cycle progression cooperate in telomere length regulation

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TRF2 inhibition triggers apoptosis and reduces tumourigenicity of human melanoma cells

Biroccio, A., Rizzo, A., Elli, R., Koering, C.-E., Belleville, A., Benassi, B., Leonetti, C., Stevens, M. F. G., D’Incalci, M., Zupi, G., et al. (2006) · European Journal of Cancer · doi:10.1016/j.ejca.2006.03.010 · Cited by 76

Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of TelomeresPreprint

Roake, C. M., & Artandi, S. E. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a026088 · Cited by 70

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1

Denchi, E. L., & de Lange, T. (2007) · Nature · doi:10.1038/nature06065 · Cited by 880

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage rsponse

Hoke, K., Mirzoeva, O. K., Bakkenist, C. J., Kastan, M. B., Petrini, J. H. J., & de Lange, T. (2004)

A two-step mechanism for TRF2-mediated chromosome-end protection

Okamoto, K., Bartocci, C., Ouzounov, I., Diedrich, J. K., Yates, J. R., & Denchi, E. L. (2013) · Nature · doi:10.1038/nature11873 · Cited by 251

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response

Karlseder, J., Hoke, K., Mirzoeva, O. K., Bakkenist, C. J., Kastan, M. B., Petrini, J. H. J., & de Lange, T. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020240 · Cited by 418

No Overt Nucleosome Eviction at Deprotected Telomeres

Wu, P. V., & de Lange, T. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01764-07 · Cited by 44