PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Geisler, Sven, Holmström, Kira M., Skujat, Diana, Fiesel, Fabienne C., Rothfuss, Oliver C., Kahle, Philipp J., Springer, Wolfdieter·2010·Nature Cell Biology

DOI 10.1038/ncb2012

Cited by (1,015)

Items 801–900 of 1,015

Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection
Mark W. Pellegrino, Cole M. Haynes · 2015 · BMC Biology
Perturbed mitochondrial Ca2+signals as causes or consequences of mitophagy induction
Alessandro Rimessi, Massimo Bonora, Saverio Marchi, Simone Patergnani, Carlo Marya Thomas Marobbio, Francesco Massimo Lasorsa, Paolo Pinton · 2013 · Autophagy
Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation
Ying Dai, Kangni Zheng, Joanne Clark, Russell Howard Swerdlow, Stefan M. Pulst, James P. Sutton, Leslie A. Shinobu, David K. Simon · 2013 · Human Molecular Genetics
Autophagy in the Fight Against Tuberculosis
Carla F. Bento, Nuno Empadinhas, V. Mendes · 2015 · DNA and Cell Biology
Mechanisms linking mitochondrial mechanotransduction and chondrocyte biology in the pathogenesis of osteoarthritis
Weizhou Jiang, Huan Liu, Rongxue Wan, Yanjiao Wu, Zhanjun Shi, Wenhua Huang · 2021 · Ageing Research Reviews
Multiple Layers of Regulation on Leaf Senescence: New Advances and Perspectives
Yuemei Zhang, Pengru Guo, Xinli Xia, Hongwei Guo, Zhonghai Li · 2021 · Frontiers in Plant Science
Protein interaction networks in neurodegenerative diseases: From physiological function to aggregation
Gaetano Calabrese, Cristen M. Molzahn, Thibault Mayor · 2022 · Journal of Biological Chemistry
Autophagy machinery in the context of mammalian mitophagy
Saori R. Yoshii, Noboru Mizushima · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
The role of mitochondrial DNA damage in the development of atherosclerosis
Emma Yu, Martin R. Bennett · 2016 · Free Radical Biology and Medicine
Enhancing autophagy in Alzheimer's disease through drug repositioning
Eshraghi, Mehdi, Ahmadi, Mazaher, Afshar, Saeid, Lorzadeh, Shahrokh, Adlimoghaddam, Aida, Rezvani Jalal, Nahid, West, Ryan, Dastghaib, Sanaz, Igder, Somayeh, Torshizi, Seyed Reza Naeimi et al. · 2022 · Pharmacology & Therapeutics
Mutations in the Intellectual Disability Gene Ube2a Cause Neuronal Dysfunction and Impair Parkin-Dependent Mitophagy
Dominik Haddad, Sven Vilain, Melissa Harju Vos, Giovanni Esposito, Samer Matta, Vera M. Kalscheuer, Katleen Craessaerts, Maarten Leyssen, Rafaella M.P. Nascimento, Angela Maria Vianna‐Morgante et al. · 2013 · Molecular Cell
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1−/− zebrafish
Smijin K. Soman, Marcus Keatinge, Mahsa Moein, Marc Da Costa, Heather Mortiboys, Alexander Skupin, Sreedevi Sugunan, Michał A. Bazała, Jacek Kuźnicki, Oliver Bandmann · 2016 · European Journal of Neuroscience
Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy
Simone Buraschi, Thomas Neill, Renato V. Iozzo · 2017 · Matrix Biology
Mitophagy in the Pathogenesis of Liver Diseases
Po‐Yuan Ke · 2020 · Cells
PINK1/Parkin-mediated mitophagy in cardiovascular disease: From pathogenesis to novel therapy
Yanze Wu, Ting Jiang, Jinghai Hua, Zhiping Xiong, Kai Dai, Hui Chen, Lei Li, Jingtian Peng, Xiaoping Peng, Zeqi Zheng et al. · 2022 · International Journal of Cardiology
Mitochondrial Dysfunction, Oxidative Stress, and Inter-Organ Miscommunications in T2D Progression
Rajakrishnan Veluthakal, Diana Esparza, Joseph M. Hoolachan, Rekha Balakrishnan, Miwon Ahn, Eunjin Oh, Chathurani S. Jayasena, Debbie C. Thurmond · 2024 · International Journal of Molecular Sciences
Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD
A. Raquel Esteves, Daniela M. Arduíno, Diana Filipa Silva, Catarina Resende Oliveira, Sandra M. Cardoso · 2011 · Parkinson s Disease
Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine
Ljubica M. Vucicevic, Maja Misirkic-Marjanovic, Verica Paunović, Tamara Kravic‐Stevovic, Tamara Martinović, Darko Ćirić, Nadja P. Marić, Sasa M. Petricevic, Ljubica M. Harhaji-Trajkovic, Vladimir Z. Bumbasirevic et al. · 2014 · Autophagy
Mechanisms, pathophysiological roles and methods for analyzing mitophagy – recent insights
Jessica A. R. Williams, Wen‐Xing Ding · 2017 · Biological Chemistry
Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin: HUMAN MUTATION
Fiesel, Fabienne C., Caulfield, Thomas R., Moussaud-Lamodière, Elisabeth L., Ogaki, Kotaro, Dourado, Daniel F.A.R., Flores, Samuel C., Ross, Owen A., Springer, Wolfdieter · 2015 · Human Mutation
Genetic mouse models for Parkinson's disease display severe pathology in glial cell mitochondria
S. Schmidt, Bettina Linnartz‐Gerlach, Sonja Mendritzki, Teresa Sczepan, Michael Lübbert, Christine C. Stichel, Hermann Lübbert · 2011 · Human Molecular Genetics
Cell death mechanisms: Cross-talk and role in disease
Boris Zhivotovsky, Sten Orrenius · 2010 · Experimental Cell Research
The landscape of Parkin variants reveals pathogenic mechanisms and therapeutic targets in Parkinson’s disease
Wei Yi, Emma J. MacDougall, Matthew Y. H. Tang, Andrea I. Krahn, Ziv Gan‐Or, Jean‐François Trempe, Edward A. Fon · 2019 · Human Molecular Genetics
K63-linked ubiquitination and neurodegeneration
Kah‐Leong Lim, Grace G.Y. Lim · 2010 · Neurobiology of Disease
Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate
Alejandro Vázquez‐Martín, Chris Van den Haute, Sílvia Cufí, Bruna Corominas-Faja, Elisabet Cuyàs, Eugeni López‐Bonet, Esther Rodríguez‐Gallego, Salvador Fernández‐Arroyo, Jorge Joven, Veerle Baekelandt et al. · 2016 · Aging
Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP
Zuriñe Antón, Ane Landajuela, Javier H. Hervás, Lidia Ruth Montes, Sonia Hernández‐Tiedra, Guillermo Velasco, Félix M. Goñi, Alicia Alonso · 2016 · Autophagy
Mitochondrial dynamics in cancer-induced cachexia
van der Ende, Miranda, Grefte, Sander, Plas, Rogier, Meijerink, Jocelijn, Witkamp, Renger F., Keijer, Jaap, van Norren, Klaske · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
Pontus Klein, Anne Kathrin Müller-Rischart, Elisa Motori, Cornelia Schönbauer, Frank Schnorrer, Konstanze F. Winklhofer, Rüdiger Klein · 2014 · The EMBO Journal
Chloroplast Degradation: Multiple Routes Into the Vacuole
Xiaohong Zhuang, Liwen Jiang · 2019 · Frontiers in Plant Science
miR‐181a/b downregulation exerts a protective action on mitochondrial disease models
Alessia Indrieri, Sabrina Carrella, Alessia Romano, Alessandra Spaziano, Elena Marrocco, Erika Fernández‐Vizarra, Sara Barbato, Mariateresa Pizzo, Yulia Ezhova, Francesca M Golia et al. · 2019 · EMBO Molecular Medicine
Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury
Wenju Li, Zhidan Xiang, Yuexian Xing, Li Shen, Shaolin Shi · 2022 · Cell Death and Disease
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells
Brian G. Coon, Sushma Timalsina, Matteo Astone, Zhenwu Zhuang, Jennifer Shea‐Ying Fang, Jinah Han, Jurgen Themen, Minhwan Chung, Young Joo Yang-Klingler, Mukesh K. Jain et al. · 2022 · The Journal of Cell Biology
Mitochondria in endothelial cells angiogenesis and function: current understanding and future perspectives
Zhen Luo, Jianbo Yao, Zhe Wang, Jianxiong Xu · 2023 · Journal of Translational Medicine
Autophagy in adipose tissue biology
Yongqing Zhang, Xiangang Zeng, Shengkan V. Jin · 2012 · Pharmacological Research
Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling
Kristi L. Norris, Rui Hao, Liangfu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J. Shaughnessy, Dennis Chou, Jin Yan, J. Paul Taylor, Simone Engelender et al. · 2015 · Journal of Biological Chemistry
Mitochondrial quality control and neurological disease: an emerging connection
Inês Pimenta de Castro, L. Miguel Martins, Roberta Tufi · 2010 · Expert Reviews in Molecular Medicine
Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases
Sheng-Fang Wang, Ming-Yue Wu, Cui-Zan Cai, Min Li, Jiahong Lu · 2016 · Journal of Ethnopharmacology
Autophagy in mammalian cells
Kadija Abounit, Tiziano Maria Scarabelli, Roy B. McCauley · 2012 · World Journal of Biological Chemistry
Hsp90 regulates autophagy and plays a role in cancer therapy
Benli Wang, Zongyan Chen, Feifei Yu, Qiao Chen, Yuxi Tian, Shumei Ma, Tiejun Wang, Xiaodong Liu · 2015 · Tumor Biology
Genetic mutations and functions of PINK1
Sumihiro Kawajiri, Shinji Saiki, Shigeto Sato, Nobutaka Hattori · 2011 · Trends in Pharmacological Sciences
Aloe Vera extract-based composite nanofibers for wound dressing applications
Raul Barbosa, Alexa Villarreal, Cristóbal Rodríguez, Heriberto De Leon, Robert Gilkerson, Karen Lozano · 2021 · Materials Science and Engineering C
Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
Angara Sureshbabu, Vineet Bhandari · 2013 · Frontiers in Physiology
Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: Functional analysis of p62 and autophagy in hypoxic neuronal cells
Tanabe, Fumito, Yone, Kazunori, Kawabata, Naoya, Sakakima, Harutoshi, Matsuda, Fumiyo, Ishidou, Yasuhiro, Maeda, Shingo, Abematsu, Masahiko, Komiya, Setsuro, Setoguchi, Takao · 2011 · Autophagy
SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance
Huan Min Yang, Hongtao Shen, Jing Li, Lian-Wang Guo · 2019 · Autophagy
Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson’s Disease
Daniel Aghaie Madsen, Sissel Ida Schmidt, Morten Blaabjerg, Morten Meyer · 2021 · Cells
Receptor protein complexes are in control of autophagy
Dalibor Mijaljica, Taras Y. Nazarko, John Hunter Brumell, Wei‐Pang Huang, Masaaki Komatsu, Mark Prescott, Anne Simonsen, Ai Yamamoto, Hong Zhang, Daniel J. Klionsky et al. · 2012 · Autophagy
The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy
Joe H. Pogson, Rachael M. Ivatt, Álvaro Sánchez-Martínez, Roberta Tufi, Emma Louise Wilson, Heather Mortiboys, Alexander J. Whitworth · 2014 · PLoS Genetics
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons
Giuseppina Amadoro, Veronica Corsetti, Fulvio Florenzano, Anna Atlante, M. T. Ciotti, Maria Patrizia Mongiardi, Rossana Bussani, Vanessa Nicolin, Stefania Lucia Nori, Michelangelo Campanella et al. · 2013 · Neurobiology of Disease
The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy
Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu · 2013 · Journal of Diabetes Research
Mitochondrial control of cell bioenergetics in Parkinson’s disease
Raquel Requejo-Aguilar, Juan Pedro Bolaños · 2016 · Free Radical Biology and Medicine
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
Sylvia Torres-Odio, Jana Key, Hans-Hermann Hoepken, Júlia Canet-Pons, Lucie Valek, Bastian Roller, Michael J. Walter, Blas Morales-Gordo, David Meierhofer, Patrick N. Harter et al. · 2017 · Journal of Neuroinflammation
Dichloroacetate induces autophagy in colorectal cancer cells and tumours
Gigin Lin, Deborah K. Hill, Gabriela Andrejeva, Jessica K.R. Boult, Helen Troy, A-C L F W T Fong, Matthew R. Orton, Rafał Panek, Harold G. Parkes, Maysam M Jafar et al. · 2014 · British Journal of Cancer
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang · 2021 · Acta Pharmaceutica Sinica B
Toxicity, biodegradation, and nutritional intervention mechanism of zearalenone
Peiran Cai, Shiqi Liu, Yuang Tu, Tizhong Shan · 2023 · The Science of The Total Environment
Mitochondrial quality control in the myocardium: Cooperation between protein degradation and mitophagy
Babette C. Hammerling, Åsa B. Gustafsson · 2014 · Journal of Molecular and Cellular Cardiology
Receptor-mediated mitophagy
Osamu Yamaguchi, Tomokazu Murakawa, Kazuhiko Nishida, Kinya Otsu · 2016 · Journal of Molecular and Cellular Cardiology
Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin
Yang Wang, Kairong Shi, Li Zhang, Guanlian Hu, Jingyu Wan, Jiajing Tang, Sheng Yin, Jiandong Duan, Ming Qin, Neng Wang et al. · 2016 · Autophagy
Regulation of autophagy by mitochondrial phospholipids in health and diseases
Paul Hsu, Yuguang Shi · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
The Role of ESX-1 in Mycobacterium tuberculosis Pathogenesis
Ka‐Wing Wong · 2017 · Microbiology Spectrum
Artesunate-induced mitophagy alters cellular redox status
Jianbin Zhang, Xin Sun, Liming Wang, Yin Kwan Wong, Yew Mun Lee, Chao Zhou, Guoqing Wu, Tongwei Zhao, Yang Liu, Liqin Lu et al. · 2018 · Redox Biology
Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice
Rogers, Robert S., Tungtur, Sudheer, Tanaka, Tomohiro, Nadeau, Lisa L., Badawi, Yomna, Wang, Hua, Ni, Hong-Min, Ding, Wen-Xing, Nishimune, Hiroshi · 2017 · Frontiers in Neuroscience
Molecular Insights into Parkinson's Disease
Jean‐Christophe Rochet, Bruce A. Hay, Ming Guo · 2012 · Progress in molecular biology and translational science
Mitochondrial dismissal in mammals, from protein degradation to mitophagy
Silvia Campello, Flavie Strappazzon, Francesco Cecconi · 2013 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Akt Phosphorylates NQO1 and Triggers its Degradation, Abolishing Its Antioxidative Activities in Parkinson's Disease
Shilin Luo, Seong Su Kang, Zhi-Hao Wang, Xia Liu, Julia X. Day, Zhiping Wu, Junmin Peng, Daxiong Xiang, Wolfdieter Springer, Keqiang Ye · 2019 · Journal of Neuroscience
Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice
Yu Sun, Fanghao Lu, Xiangjing Yu, Bingzhu Wang, Jian Chen, Fangping Lu, Shuo Peng, Xiaojiao Sun, Miao Yu, He Chen et al. · 2020 · Aging and Disease
Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb
Lisa Glasl, Karina Kloos, Florian Giesert, Anne Henriette Janice Röthig, Barbara Di Benedetto, Ralf Kühn, Jingzhong Zhang, Ulrich Hafen, Julia Zerle, Andreas Hofmann et al. · 2012 · Experimental Neurology
Molecular machinery of macroautophagy and its deregulation in diseases
Alan S.L. Wong, Zelda H. Cheung, Nancy Y. Ip · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease
Lynette Lim, Vernice R. Jackson-Lewis, Loo Chin Wong, Guanghou Shui, Angeline XH Goh, Sashi Kesavapany, Andrew M. Jenner, Marc L. Fivaz, Serge Przedborski, Markus Rene Wenk · 2011 · Cell Death and Differentiation
Mitochondrial function in vascular endothelial cell in diabetes
Meenal Pangare, Ayako Makino · 2012 · Journal of Smooth Muscle Research
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
Aitor Martinez, Benoit Louis Philippe Lectez, Juanma Ramírez, Oliver Popp, James David Sutherland, Sylvie Urbé, Gunnar Dittmar, Michael J. Clague, Ugo Mayor · 2017 · Molecular Neurodegeneration
Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease
Rosa, Alexandra I., Fonseca, Inês, Nunes, Maria João, Moreira, Sara, Rodrigues, Elsa, Carvalho, Andreia Neves, Rodrigues, Cecília M.P., Gama, Maria João, Castro-Caldas, Margarida · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
PINK1/Parkin mediated mitophagy ameliorates palmitic acid-induced apoptosis through reducing mitochondrial ROS production in podocytes
Xu-shun Jiang, Xuemei Chen, Wei Hua, Junling He, Ting Liu, Xun-jia Li, Jiang‐min Wan, Hua Gan, Xiaogang Du · 2020 · Biochemical and Biophysical Research Communications
Selective autophagy as a therapeutic target for neurological diseases
Weilin Xu, Umut Ocak, Liansheng Gao, Sheng Tu, Cameron Lenahan, Jianmin Zhang, Anwen Shao · 2020 · Cellular and Molecular Life Sciences
Multitasking guardian of mitochondrial quality: Parkin function and Parkinson’s disease
Iryna Kamienieva, Jerzy Duszyński, Joanna Szczepanowska · 2021 · Translational Neurodegeneration
Mitochondrial Dysfunction is a Converging Point of Multiple Pathological Pathways in Amyotrophic Lateral Sclerosis
Ping Shi, Yanming Wei, Jia Yu Zhang, József Gál, Haining Zhu · 2010 · Journal of Alzheimer s Disease
A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity
Michael Lamar Seibenhener, Yifeng Du, Maria Teresa Díaz-Meco, Jorge Moscat, Michael C. Wooten, Marie W. Wooten · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Integrating multiple aspects of mitochondrial dynamics in neurons: Age-related differences and dynamic changes in a chronic rotenone model
Beth A. Arnold, Steven J. Cassady, Victor S. Van Laar, Sarah B. Berman · 2010 · Neurobiology of Disease
Parkin Plays a Role in Sporadic Parkinson's Disease
Ted M. Dawson, Valina Lynn Dawson · 2013 · Neurodegenerative Diseases
SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria
Hitoshi Murata, Masakiyo Sakaguchi, Ken Kataoka, Nam-ho Huh · 2013 · Molecular Biology of the Cell
Parkin Regulation and Neurodegenerative Disorders
Chengwu Zhang, Liting Hang, Tso‐Pang Yao, Kah‐Leong Lim · 2016 · Frontiers in Aging Neuroscience
Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels
Guobing� Li, Ruoqiu Fu, Han‐Ming Shen, Jing Zhou, Xiaoye Hu, Yan‐Xia Liu, Yu-Nong Li, Hongwei Zhang, Xin Bo Liu, Yan-Hao Zhang et al. · 2017 · Oncotarget
VPS34 stimulation of p62 phosphorylation for cancer progression
Xiaofei Jiang, Y Bao, Hongrui Liu, Xinhui Kou, Zhaoyun Zhang, Fanghui Sun, Zhong‐Ming Qian, Zhuofeng Lin, X Li, Xiaoqiang Liu et al. · 2017 · Oncogene
Extracellular Signal-Regulated Kinase/Nuclear Factor-Erythroid2-like2/Heme Oxygenase-1 Pathway-Mediated Mitophagy Alleviates Traumatic Brain Injury-Induced Intestinal Mucosa Damage and Epithelial Barrier Dysfunction
Yinlong Liu, Zhongyuan Bao, Xiupeng Xu, Honglu Chao, Chao Lin, Zheng Li, Yan Liu, Xiaoming Wang, Yongping You, Ning Liu et al. · 2017 · Journal of Neurotrauma
Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases
Mafalda Escobar‐Henriques, Mariana Joaquim · 2019 · Frontiers in Physiology
Mitophagy and Innate Immunity in Infection.
Dong‐Hyung Cho, Jin Kyung Kim, Eun‐Kyeong Jo · 2020 · Europe PMC (PubMed Central)
Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases
Albin A John, Aaron Kubosumi, P. Hemachandra Reddy · 2020 · Cells
Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC
Yiting Liu, Danielle A. Sliter, Mario Karam Shammas, Xiaoping Huang, Chunxin Wang, Hannah R. Calvelli, Dragan Maric, Derek P. Narendra · 2021 · Autophagy
Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: Mechanistic relationship and differential sensitivity to intervention
Miranda L. Tradewell, Laura A. Cooper, Sandra Minotti, Heather D. Durham · 2011 · Neurobiology of Disease
Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
Minjuan Bian, Jie Liu, Xiaoqi Hong, Mei Yu, Yu‐Fang Huang, Zhejin Sheng, Jian Fei, Fang Ping Huang · 2012 · PLoS ONE
The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins
Emmanuel Taillebourg, Isabel Pombo Grégoire, Perrine Viargues, Anne‐Claire Jacomin, Dominique Thevenon, Mathias Faure, Marie‐Odile Fauvarque · 2012 · Autophagy
Fibroblast autophagy in fibrotic disorders
Domenico Del Principe, Pasquale Lista, Walter Malorni, Anna Maria Giammarioli · 2012 · The Journal of Pathology
Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart
Liang, Wenjing, Moyzis, Alexandra G., Lampert, Mark A., Diao, Rachel Y., Najor, Rita H., Gustafsson, Åsa B. · 2020 · Aging Cell
Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer
Robert Weil, Emmanuel Laplantine, Shannel Curic, Pierre Génin · 2018 · Frontiers in Immunology
Endo-lysosomal pathway and ubiquitin-proteasome system dysfunction in Alzheimer's disease pathogenesis
Jiqing Cao, Margaret B. Zhong, Carlos A. Toro, Larry Zhang, Dongming Cai · 2019 · Neuroscience Letters
Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response
Guillermo López‐Doménech, Jack H. Howden, Christian Covill‐Cooke, Corinne Morfill, Jigna V. Patel, Roland W. Bürli, Damian C. Crowther, Nicol Birsa, Nicholas J. Brandon, Josef T. Kittler · 2021 · The EMBO Journal
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
Mohamed A. Eldeeb, Andrew N. Bayne, Armaan Fallahi, Thomas Goiran, Emma J. MacDougall, Andrea Soumbasis, Cornelia E. Zorca, Jace Jones-Tabah, Rhalena A. Thomas, Nathan C. Karpilovsky et al. · 2024 · Proceedings of the National Academy of Sciences
Mitochondrial Dysfunction and Signaling in Diabetic Kidney Disease: Oxidative Stress and Beyond
Nicole Flemming, Linda A. Gallo, Josephine Maree Forbes · 2018 · Seminars in Nephrology
c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration
Murata, Hitoshi, Khine, Cho Cho, Nishikawa, Akane, Yamamoto, Ken-ichi, Kinoshita, Rie, Sakaguchi, Masakiyo · 2018 · Journal of Biological Chemistry
Mitochondrial Dynamics and Parkinson's Disease: Focus on Parkin
Kah‐Leong Lim, Xiao‐Hui Ng, Lim Gui-Yin Grace, Tso‐Pang Yao · 2011 · Antioxidants and Redox Signaling
Mitochondrial dysfunctioning and neuroinflammation: Recent highlights on the possible mechanisms involved in Traumatic Brain Injury
Deepak Kumar Sahel, Meenakshi Kaira, Khadga Raj Aran, Shakshi Sharma, Shamsher Singh · 2019 · Neuroscience Letters