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Mitophagy in Alzheimer’s Disease and Other Age-Related Neurodegenerative Diseases

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Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy

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Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging

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Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction

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Mitostasis, Calcium and Free Radicals in Health, Aging and Neurodegeneration

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Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal Dystrophy

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Identifying Therapeutic Agents for Amelioration of Mitochondrial Clearance Disorder in Neurons of Familial Parkinson Disease

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Mitophagy and the Brain

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Molecular mechanisms of mitophagy and its roles in neurodegenerative diseases

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Mitochondria, a Key Target in Amyotrophic Lateral Sclerosis Pathogenesis

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Reversible mitophagy drives metabolic suppression in diapausing beetles

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Biochemical and Molecular Pathways in Neurodegenerative Diseases: An Integrated View

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Mitophagy Modulation, a New Player in the Race against ALS

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Mitophagy in neurodegenerative disease pathogenesis

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Mitophagy and Neurodegeneration: Between the Knowns and the Unknowns

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Impact of ageing and disuse on neuromuscular junction and mitochondrial function and morphology: Current evidence and controversies

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Mitophagy’s impacts on cancer and neurodegenerative diseases: implications for future therapies

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Mitophagy impairment in neurodegenerative diseases: Pathogenesis and therapeutic interventions

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Genes Implicated in Familial Parkinson’s Disease Provide a Dual Picture of Nigral Dopaminergic Neurodegeneration with Mitochondria Taking Center Stage

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Identification of a novel interaction of FUS and syntaphilin may explain synaptic and mitochondrial abnormalities caused by ALS mutations

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Bnip3 regulates airway smooth muscle cell focal adhesion and proliferation

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Interplay between Mitophagy and Inflammasomes in Neurological Disorders

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Epigenetic Explorations of Neurological Disorders, the Identification Methods, and Therapeutic Avenues

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The role of cardiolipin in mitochondrial dynamics and quality control in neuronal ischemia/reperfusion injury

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Development of abnormalities at the neuromuscular junction in the SOD1-G93A mouse model of ALS: dysfunction then disruption of postsynaptic structure precede overt motor symptoms

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Maintenance mechanisms of circuit-integrated axons

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Dominant and recessive congenital myasthenic syndromes caused by SYT2 mutations

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Mitochondrial dysfunction, cause or consequence in neurodegenerative diseases?

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Defective PTEN-induced kinase 1/Parkin mediated mitophagy and neurodegenerative diseases

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Axonopathy Underlying Amyotrophic Lateral Sclerosis: Unraveling Complex Pathways and Therapeutic Insights

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Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease

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Isoginkgetin antagonizes ALS pathologies in its animal and patient iPSC models via PINK1-Parkin-dependent mitophagy

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Receptor-mediated mitophagy: a new target of neurodegenerative diseases

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Mitochondrial Quality Control in Neurodegeneration and Cancer: A Common Denominator, Distinct Therapeutic Challenges

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Oxaloacetate treatment preserves motor function in SOD1G93A mice and normalizes select neuroinflammation-related parameters in the spinal cord

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Alzheimer's Disease–Associated Amyloid-β Precursor Protein Prevents Aging Stress–Induced Mitophagy and Fumarate Depletion to Improve Antitumor Immunity

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Targeting mitophagy for neurological disorders treatment: advances in drugs and non-drug approaches

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The Neuromuscular Junction: A Shared Vulnerability in Aging and Disease

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Mitochondrial dysfunction following repeated administration of alprazolam causes attenuation of hippocampus-dependent memory consolidation in mice

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Comparative Study of Structural and Functional Rearrangements in Skeletal Muscle Mitochondria of SOD1-G93A Transgenic Mice at Pre-, Early-, and Late-Symptomatic Stages of ALS Progression

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A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia

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Identification of adrenergic presynaptic and postsynaptic protein locations at neuromuscular junctions, their decrease during aging, and recovery by nicotinamide mononucleotide administration

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Modeling neuromuscular junctions in vitro: A review of the current progress employing human induced pluripotent stem cells

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Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS

Eckardt, A., Marble, C., Fern, B., Moritz, H., Kotula, C. A., Ke, J., Rebancos, C., Robertson, S., Nishimune, H., & Suzuki, M. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1527181 · Cited by 5 · see citing works

Power and Endurance: Polar Opposites or Willing Partners?

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A retrograde transit filter mediated by optineurin controls mitostasis in distal axonsPreprint

Marahori, N. A., Gailer, B., Schifferer, M., Kleele, T., Iatroudi, A., Hannan, S. B., Avramopoulos, P., Engelhardt, S. H., Lakadamyali, M., Brill, M. S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.28.604753 · Cited by 3 · see citing works

Disease-associated mutations in C-terminus of HSP70 interacting protein (CHIP) impair its ability to negatively regulate mitophagy

Earnshaw, R., Zhang, Y. T., Heymann, G., Fujisawa, K., Hui, S., Kapadia, M., Kalia, L. V., & Kalia, S. K. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106625 · Cited by 2 · see citing works

Fluid-based biomarkers of amyotrophic lateral sclerosis: recent advances and future prospects

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Thyroarytenoid Oxidative Metabolism and Synaptic Signaling Dysregulation in the Female Pink1−/− Rat

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Exploring Mitochondrial Quality in Aging and Neurodegenerative Diseases

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Mitochondrial Redox Status Regulates Glycogen Metabolism via Glycogen Phosphorylase Activity

Sakamoto, I., Shibuya, S., Nojiri, H., Takeno, K., Nishimune, H., Yaku, K., Nakagawa, T., Ishijima, M., & Shimizu, T. (2024) · Antioxidants · doi:10.3390/antiox13111421 · Cited by 1 · see citing works

Mammalian Sterile 20-Like Kinase 2 Knockdown Alleviates Neuropathic Pain in Rats by Mitochondrial Protection

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C9orf72-ALS mutation drives basal mitophagy impairments in iNeurons

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Changes in Als2 Expression Leads to Different Outcomes on the Expression of Two NF-kB Targeted Genes in N2a and C2C12 Cell Lines

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Mitochondrial dysfunction and autophagy in neurodegeneration

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Identification of a Novel Interaction of FUS and Syntaphilin May Explain Synaptic and Mitochondrial Abnormalities Caused by ALS MutationsPreprint

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Identification of a Novel Interaction of FUS and Syntaphilin May Explain Synaptic and Mitochondrial Abnormalities Caused by ALS MutationsPreprint

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Sphingolipid metabolism in the regulation of mitophagy: implications in cancer therapy, immune cell function, and neurodegeneration

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C9orf72-ALS mutation drives mitophagy impairments in iNeuronsPreprint

Lee, J., Granger, S. M., Roome, K., Allen, S. P., Ferraiuolo, L., Shaw, P. J., & Mortiboys, H. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.28.640849

Activation of aortic baroreceptors depresses the somato–lumbar sympathetic reflex, reducing hindlimb muscle contractile force

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Rôle du muscle squelettique dans la Sclérose Latérale Amyotrophique : apport de modèles transgéniques conditionnels

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Étude de la composante neuroinflammatoire dans les DFT/SLA

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From homeostasis to pathology, organelle-specific autophagy in skeletal muscle: a PRISMA-ScR scoping review

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Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

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Restoring mitochondria and associated chaperone function: New therapeutic strategies for neurodegenerative diseases

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Neuromuscular Junction Degeneration in Skeletal Muscle Atrophy: Disease-Specific Mechanisms, Evidence-Informed Stratification, and Therapeutic Windows

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Neuromuscular junction pathology in amyotrophic lateral sclerosis and emerging molecular therapeutic strategies

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Rapamycin treatment augments motor neuron degeneration in SOD1^G93Amouse model of amyotrophic lateral sclerosis

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Differential regulation of L84F SOD1 in motor neurons and skeletal muscles: an insight into ALS pathology

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Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation

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