Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

Di Micco, Raffaella, Sulli, Gabriele, Dobreva, Miryana, Liontos, Michalis, Botrugno, Oronza A., Gargiulo, Gaetano, dal Zuffo, Roberto, Matti, Valentina +7 more·2011·Nature Cell Biology

Cited by (391)

Items 201–300 of 391

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  5. Supplementary Materials and Methods
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  6. Characterization of the EBV-Induced Persistent DNA Damage Response
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  7. Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production
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  8. 3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing
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  9. Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells
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  10. Senescence-Associated Heterochromatin Foci Suppress γ-H2AX Focus Formation Induced by Radiation Exposure
    Takashi Oizumi, Tomoya Suzuki, Junya Kobayashi, Asako Nakamura · 2024 · International Journal of Molecular Sciences
  11. MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context
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  15. Mitogen‐activated protein kinase p38 and retinoblastoma protein signalling is required for DNA damage‐mediated formation of senescence‐associated heterochromatic foci in tumour cells
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  16. One-step Protocol for Evaluation of the Mode of Radiation-induced Clonogenic Cell Death by Fluorescence Microscopy
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  19. Genes and pathways involved in senescence bypass identified by functional genetic screens
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  20. Acute dyskerin depletion triggers cellular senescence and renders osteosarcoma cells resistant to genotoxic stress-induced apoptosis
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  21. Lamin B1 overexpression alters chromatin organization and gene expression
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  22. p19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation
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  30. Metabolic perturbation of epigenome by inhibiting S -adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells
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  42. RAS, cellular senescence and transformation
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  43. RETRACTED: Inhibition of Vascular Endothelial Growth Factor A and Hypoxia-Inducible Factor 1α Maximizes the Effects of Radiation in Sarcoma Mouse Models Through Destruction of Tumor Vasculature
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  44. Detecting Senescence: Methods and Approaches
    Elizabeth P. Crowe, Timothy Nacarelli, Alessandro Bitto, Chad A. Lerner, Christian Sell, Claudio A. Torres · 2014 · Methods in molecular biology
  45. Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells
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  49. A High-Content Screening Assay for Small-Molecule Modulators of Oncogene-Induced Senescence
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  50. p300/Sp1‐Mediated High Expression of p16 Promotes Endothelial Progenitor Cell Senescence Leading to the Occurrence of Chronic Obstructive Pulmonary Disease
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  51. Spiro[chromane‐2,4′‐piperidine]‐Based Histone Deacetylase Inhibitors with Improved in vivo Activity
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