Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

Di Micco, Raffaella, Sulli, Gabriele, Dobreva, Miryana, Liontos, Michalis, Botrugno, Oronza A., Gargiulo, Gaetano, dal Zuffo, Roberto, Matti, Valentina +7 more·2011·Nature Cell Biology
DOI 10.1038/ncb2170

Cited by (391)

Items 301–391 of 391

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  7. Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation
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  10. Cell Senescence
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  14. RPA hyperphosphorylation hinders the resolution of R-loops and G-quadruplex-associated R-loops during RAS-driven senescence
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  17. UHRF1 overexpression generates distinct senescent states with different Tp53 dependencies
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  18. Senescence in aging
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  19. 17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cell
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  20. Cellular senescence and aging at the crossroad between immunity and cancer
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  21. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression
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  22. p53: Guardian of the Metabolome
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  23. Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells
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  24. DNA Damage Response Suppresses Epstein-Barr Virus-Driven Proliferation of Primary Human B Cells
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  25. Induction of cellular senescence as a novel therapeutic strategy for melanoma treatment
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  26. The Two Faces of Senescence-Associated Epigenetic Alterations: Tumor Suppressors and Oncogenic Drivers
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  27. Premalignancy and Cellular Senescence
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  28. Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE progeroid syndrome
    Lolita S. Nidadavolu · 2013 · D-Scholarship@Pitt (University of Pittsburgh)
  29. Aging of Murine Hematopoietic Stem Cells
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  30. Role of VHL in DNA double-strand break repair and genomic instability in renal cell carcinoma
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  31. An in vivo and in vitro study of stress-induced senescence in neurones and its role in neurodegeneration
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  32. Investigating senescence in cellular plasticity and tissue regeneration
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  33. Identification of Essential Genes in Hepatocellular Carcinomas using CRISPR Screening
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  34. On the Origin of Carcinoma
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  35. Pathway Profiling Of Replicative And Induced Senescence
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  36. Cell Senescence
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  37. Senescence
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  38. Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes
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  39. 1 0 7
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  40. Inflammatory cancer associated fibroblasts decisive role in therapy resistance among rectal cancer patients
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  41. Re-Evaluation of Different Senescent Hallmarks in Therapy-Induced Senescence of Oral Squamous Cell Carcinoma
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  42. An Overview of the Role of Senescence in Cancer
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  43. Resolving Geroplasticity to the Balance of Rejuvenins and Geriatrins
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  44. Supplementary Materials and Methods from A Synthetic Lethality–Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
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  46. Data from Metabolic Regulator IAPP (Amylin) Is Required for BRAF and RAS Oncogene-Induced Senescence
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  47. Data from Metabolic Regulator IAPP (Amylin) Is Required for BRAF and RAS Oncogene-Induced Senescence
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  48. DNA Replication Stress and Genome Instability in Breast Cancer
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  49. Nuclear expansion drives chromatin structure remodeling in aging neurons
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  50. RPE Senescence and Its Implication in Age-Related Macular Degeneration
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  51. TRIP13 protects pancreatic cancer cells against intrinsic and therapy-induced DNA replication stress
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  52. Precise Mapping of Physiological DSBs Using In-Suspension Break Labeling In Situ and Sequencing (sBLISS)
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  54. Additional file 12 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
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  55. Additional file 1 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  56. Additional file 6 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  57. Additional file 3 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  58. Additional file 13 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  59. Additional file 2 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  60. Additional file 11 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Qi Wang, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  61. Additional file 10 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  62. Additional file 8 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  63. Additional file 7 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  64. Additional file 5 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Qi Wang, Junsheng Chen, Kuai, Yi-yang et al. · 2024 · Figshare
  65. Additional file 4 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  66. Additional file 9 of Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
    Xiong, Fei, Wang, Da, Xiong, Wei, Wang, Xin, Huang, Wen-hua, Wu, Guan-hua, Wenzheng Liu, Wang, Qi, Chen, Jun-sheng, Kuai, Yi-yang et al. · 2024 · Figshare
  67. Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications
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    Mirna Saker · 2015 · theses.fr (ABES)
  70. Characterization of the Signaling Pathways Involved in Cellular Cannibalism Elicited by Ionizing Radiation
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  71. Étude comparative des effets moléculaires et cellulaires induits par des rayonnements X de différentes énergies
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  72. The role of Activin signaling pathway in the initiation and progression of pancreatic cancer
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  73. Generation of antisense RNAs at convergent gene loci in cells undergoing senescence
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  75. Metabolic homeostasis and regulatory mechanisms of cellular senescence : roles of ITPR2-mediated calcium fluxes and mevalonate pathway
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  80. Senolytic drug discovery and mechanisms of action in BRAF-V600E oncogene-induced senescence
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  88. BindingDB Entry 50043074: Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4'-piperidine] based histone deacetylase inhibitors.
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  89. A focus on foci: How spatio-temporal regulation of the DNA damage response is crucial for DDR activation and cell fate
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  90. The Senescent Cell Induced Bystander Effect
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  91. DNA damage recognition in the normal epithelium of human prostate and seminal vesicles
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