Stat3 controls lysosomal-mediated cell death in vivo

Kreuzaler, Peter A., Staniszewska, Anna D., Li, Wenjing, Omidvar, Nader, Kedjouar, Blandine, Turkson, James, Poli, Valeria, Flavell, Richard A., Clarkson, Richard W. E., Watson, Christine J.·2011·Nature Cell Biology

DOI 10.1038/ncb2171

Cited by (312)

Items 101–200 of 312

Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer
Xin Jin, Wenke Jin, Linlin Tong, Jia Zhao, Lan Zhang, Na Lin · 2024 · Acta Pharmaceutica Sinica B
ATG proteins mediate efferocytosis and suppress inflammation in mammary involution
Irina Teplova, Fred Lozy, Sandy M. Price, Sukhwinder Singh, Nicola Barnard, Robert D. Cardiff, Raymond B. Birge, Vassiliki Karantza · 2013 · Autophagy
STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas
Sylvia Timme, S Ihde, Christiane Daniela Fichter, Verena Waehle, Ljudmila Bogatyreva, K Atanasov, I Kohler, Anja Schöpflin, Helene Geddert, Gerhard Faller et al. · 2013 · Oncogene
Ion-current-based Proteomic Profiling of the Retina in a Rat Model of Smith-Lemli-Opitz Syndrome
Chengjian Tu, Jun Li, Xiao-Sheng Jiang, Lowell G. Sheflin, Bruce A. Pfeffer, Matthew D. Behringer, Steven J. Fliesler, Jun Qu · 2013 · Molecular & Cellular Proteomics
The Biology of Zinc Transport in Mammary Epithelial Cells: Implications for Mammary Gland Development, Lactation, and Involution
N. Mccormick, S. Hennigar, K. Kiselyov, S. Kelleher · 2014 · Journal of mammary gland biology and neoplasia
A Truncated Form of IKKα Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer
Pol Margalef, Vanesa Fernández‐Majada, Alberto Villanueva, Ricard Garcia‐Carbonell, Mar Iglesias, Laura López-Vilaró, María Martínez‐Iniesta, Jordi Villà-Freixa, María Carmen Mulero, Montserrat G. Andreu et al. · 2012 · Cell Reports
Cysteine cathepsins: A long and winding road towards clinics
Monika Biasizzo, Urban Javoršek, Eva Vidak, Miki Zarić, Boris Turk · 2022 · Molecular Aspects of Medicine
Comparative mammary gland postnatal development and tumourigenesis in the sheep, cow, cat and rabbit: Exploring the menagerie
Katherine Hughes · 2020 · Seminars in Cell and Developmental Biology
Cleavage of Histone 3 by Cathepsin D in the Involuting Mammary Gland
Zhila Khalkhali‐Ellis, William Goossens, Naira V. Margaryan, Mary J.C. Hendrix · 2014 · PLoS ONE
Rac1 Controls Both the Secretory Function of the Mammary Gland and Its Remodeling for Successive Gestations
Nasreen Akhtar, Weiping Li, Aleksander Mironov, Charles H. Streuli · 2016 · Developmental Cell
Serotonin: A Local Regulator in the Mammary Gland Epithelium
Nelson D. Horseman, R.J. Collier · 2013 · Annual Review of Animal Biosciences
Cysteine cathepsins as therapeutic targets in inflammatory diseases
M. Vizovišek, Eva Vidak, Urban Javoršek, G. Mikhaylov, Andreja Bratovš, B. Turk · 2020 · Expert opinion on therapeutic targets
STAT3beta, a distinct isoform from STAT3
Huixiang Zhang, Ping-Lian Yang, En‐Min Li, Li‐Yan Xu · 2019 · The International Journal of Biochemistry & Cell Biology
Intracellular metal ion-based chemistry for programmed cell death
Yawen You, Zhongying Guo, Tyler Wolter, Quanyin Hu · 2025 · Chemical Society Reviews
ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution
Stephen R. Hennigar, Young Ah Seo, Supriya Sharma, David I. Soybel, Shannon L. Kelleher · 2015 · Scientific Reports
Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs
Anne‐Marie Ellegaard, Peter Brian Bach, Marja Jäättelä · 2020 · Reviews of physiology, biochemistry and pharmacology
Quantitative chemical proteomics profiling of de novo protein synthesis during starvation-mediated autophagy
Jigang Wang, Jianbin Zhang, Yew Mun Lee, Pin-Lang Koh, Shukie Ng, Feichao Bao, Qingsong Lin, Han‐Ming Shen · 2016 · Autophagy
Autophagy-lysosomal pathway impairment and cathepsin dysregulation in Alzheimer’s disease
Alquiandra Stefani Ferreira Mançano, Juliana Guanaes Pina, Bruna Rojas Froes, Juliana Mozer Sciani · 2024 · Frontiers in Molecular Biosciences
Hypothyroidism decreases JAK/STAT signaling pathway in lactating rat mammary gland
Fiorella Campo Verde Arboccó, Fabio Andrés Persia, María Belén Hapon, Graciela A. Jahn · 2017 · Molecular and Cellular Endocrinology
Organelles coordinate milk production and secretion during lactation: Insights into mammary pathologies
Wenting Dai, Robin R. White, Jianxin Liu, Hongyun Liu · 2022 · Progress in Lipid Research
Dynamic architectural interplay between leucocytes and mammary epithelial cells
Jessica R. Hitchcock, Katherine Hughes, Olivia B. Harris, Christine J. Watson · 2019 · FEBS Journal
The Role of Cysteine Peptidases in Hematopoietic Stem Cell Differentiation and Modulation of Immune System Function
Milica Perišić Nanut, Urša Pečar Fonović, Tanja Jakoš, Janko Kos · 2021 · Frontiers in Immunology
Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes
Anni M. Wärri, Katherine Loree Cook, Rong Hu, Lü Jin, Alan L. Zwart, David R. Soto‐Pantoja, Jie Liu, Toren Finkel, Robert C. Clarke · 2018 · Cell Death Discovery
Transcriptomes reveal alterations in gravity impact circadian clocks and activate mechanotransduction pathways with adaptation through epigenetic change
Theresa Casey, Osman Valli PATEL, Karen I. Plaut · 2015 · Physiological Genomics
Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome
Kelsey E. Johnson, Timothy J. Heisel, Mattea Allert, Annalee Fürst, Nikhila Yerabandi, Dan Knights, Katherine M. Jacobs, Eric F. Lock, Lars Bode, David A. Fields et al. · 2024 · Cell Genomics
Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling
Halil Bagci, Mélanie Laurin, J Huber, William J. Muller, J-F Côté · 2014 · Cell Death and Disease
Small RNA deep sequencing reveals the expressions of microRNAs in ovine mammary gland development at peak-lactation and during the non-lactating period
Jiqing Wang, Zhiyun Hao, Jiang Hu, Xiu Liu, Shaobin Li, Jianqing Wang, Jiyuan Shen, Yize Song, Na Ke, Yuzhu Luo · 2020 · Genomics
Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
Cliff J. Luke, Stephanie T. Markovina, Misty L. Good, Ira E. Wight, Brian J. Thomas, John M. Linneman, Wyatt E. Lanik, Olga Koroleva, Maggie R. Coffman, Mark T. Miedel et al. · 2022 · Communications Biology
Mammary mechanobiology – investigating roles for mechanically activated ion channels in lactation and involution
Teneale A. Stewart, Katherine Hughes, Alexander J. Stevenson, Natascia Marino, Adler L. Ju, Michael Morehead, Felicity M. Davis · 2020 · Journal of Cell Science
Functional status of STAT3 and MAPK3/1 signaling pathways in granulosa cells during bovine follicular deviation
Bernardo Garziera Gasperin, Monique Tomazele Rovani, Rogério Ferreira, Gustavo Freitas Ilha, Vilceu Bordignon, Paulo Bayard Dias Gonçalves, Raj Duggavathi · 2014 · Theriogenology
Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling
Kazuhito Sakamoto, B. Wehde, K. Yoo, Taemook Kim, Nirakar Rajbhandari, H. Shin, Aleata A. Triplett, P. D. Rädler, F. Schuler, A. Villunger et al. · 2016 · Molecular and Cellular Biology
Deciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast Cancer
Virginia F. Borges, Alan M. Elder, Traci Renae Lyons · 2016 · Frontiers in Oncology
Stat3-mediated alterations in lysosomal membrane protein composition
Bethan Lloyd‐Lewis, Caroline C. Krueger, Timothy J. Sargeant, Michael E. D’Angelo, Michael J. Deery, Renata Feret, Julie A. Howard, Kathryn Susan Lilley, Christine J. Watson · 2018 · Journal of Biological Chemistry
Characterizing Adversity of Lysosomal Accumulation in Nonclinical Toxicity Studies: Results from the 5th ESTP International Expert Workshop
Barbara F. Lenz, Annamaria Braendli-Baiocco, Jeffery A. Engelhardt, Pierluigi Fant, Holger Fischer, Sabine Francke, Ryo Fukuda, Sibylle Gröters, Takanori Harada, H. Harleman et al. · 2018 · Toxicologic Pathology
Lysosome Depletion-Triggered Autophagy Impairment in Progressive Kidney Injury
Xiaocui Chen, Zhihang Li, Chen Yang, Ji‐Xin Tang, Hui-yao Lan, Huafeng Liu · 2021 · Kidney Diseases
SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes
Youn Kyung Choi, Yu‐Jeong Choi, Yu‐Jeong Choi, Yee Jin Yun, Kang Min Lee, Kangwook Lee, HyeHyun Yoo, Yong Cheol Shin, Seong‐Gyu Ko · 2016 · Oncotarget
STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB
Lin Li, Bin Sun, Yun Gao, Huanmin Niu, Huiqing Yuan, Hong‐Xiang Lou · 2018 · Biochemical Pharmacology
Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism
Chew Leng Lim, Yu Zuan Or, Zoe Ong, Hwa Hwa Chung, Hirohito Hayashi, Smeeta Shrestha, Shunsuke Chiba, Feng Lin, Valerie C. L. Lin · 2020 · eLife
LabCaS: Labeling calpain substrate cleavage sites from amino acid sequence using conditional random fields
Yongxian Fan, Yang Zhang, Hong‐Bin Shen · 2012 · Proteins Structure Function and Bioinformatics
What is the evidence for antibodies to LAMP-2 in the pathogenesis of ANCA associated small vessel vasculitis?
Renate Kain, Andrew Jackson Rees · 2012 · Current Opinion in Rheumatology
Sirt1 coordinates with ERα to regulate autophagy and adiposity
Zhipeng Tao, Limin Shi, Jane Parke, Louise Zheng, Wei Jun Gu, Xiaocheng Charlie Dong, Dongmin Liu, Zongwei Wang, Aria F. Olumi, Zhiyong Cheng · 2021 · Cell Death Discovery
Stat5 in breast cancer: potential oncogenic activity coincides with positive prognosis for the disease
Itamar Barash · 2012 · Carcinogenesis
Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis
Xiaohong Huang, Youhua Huang, Ying Yang, Shina Wei, Qiwei Qin · 2014 · Fish & Shellfish Immunology
Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer
Rosa Zaragozá, Elena R. García–Trevijano, Ana M. Lluch, Gloría Ribas, Juan R. Vinã · 2015 · IUBMB Life
A 3-D in vitro co-culture model of mammary gland involution
Jonathan J. Campbell, Laur-Alexandru Botos, Timothy J. Sargeant, Natalia Davidenko, Ruth Elizabeth Cameron, Christine J. Watson · 2014 · Integrative Biology
Autophagy regulates functional differentiation of mammary epithelial cells
Jessica L. Epps, Scott J. Pearson, Harold Ross Payne, Rola Barhoumi, Monique Rijnkels, Weston W. Porter · 2020 · Autophagy
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3‐kinase regulatory subunits p55α and p50α regulate autophagy <i>in vivo</i>
Pensa, Sara, Lloyd‐Lewis, Bethan, Sargeant, Timothy J., Resemann, Henrike K., Kahn, C. Ronald, Watson, Christine J. · 2014 · The FEBS Journal
Stat3‐Atg5 signal axis inducing autophagy to alleviate hepatic ischemia‐reperfusion injury
Yu‐fang Han, Yanbing Zhao, Jun Li, Li Li, Yong‐gan Li, Shipeng Li, Zhong‐dong Li · 2017 · Journal of Cellular Biochemistry
Poloxamer 188 rescues MPTP‐induced lysosomal membrane integrity impairment in cellular and mouse models of Parkinson's disease
Hongli Dong, Yuanyuan Qin, Yuyu Huang, Dongliang Ji, Feng Wu · 2019 · Neurochemistry International
The Cellular Organization of the Mammary Gland: Insights From Microscopy
Caleb A. Dawson, Jane E. Visvader · 2021 · Journal of Mammary Gland Biology and Neoplasia
TNFα Post‐Translationally Targets ZnT2 to Accumulate Zinc in Lysosomes
Stephen R. Hennigar, Shannon L. Kelleher · 2015 · Journal of Cellular Physiology
3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages
Ning Liu, Ying Yang, Jingqing Chen, Hai Jia, Yunchang Zhang, Da Jiang, Guoyao Wu, Zhenlong Wu · 2020 · Environmental Pollution
ZnT2 is critical for lysosome acidification and biogenesis during mammary gland involution
Olivia C. Rivera, Stephen R. Hennigar, Shannon L. Kelleher · 2018 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation
Yuchen Nan, Chunyan Wu, Yan‐Jin Zhang · 2018 · Viruses
LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy
Pin Li, Qin Li, Nilima Biswas, Hong Xin, Tanja Diemer, Lixian Liu, Lorena Pérez, Giovanni Paternostro, Carlo Piermarocchi, Sergii Domanskyi et al. · 2021 · EMBO Molecular Medicine
Transcriptomic analysis reveals key regulators of mammogenesis and the pregnancy-lactation cycle
Yuanyuan Zhou, Wei Gong, Jingfa Xiao, Jiayan Wu, Linlin Pan, XiaoNuan Li, Xumin Wang, Weiwei Wang, Songnian Hu, Jun Myoung Yu · 2014 · Science China Life Sciences
Shotgun proteomics reveals possible mechanisms for cognitive impairment in Mucopolysaccharidosis I mice
Guilherme Baldo, Daniel M. Lorenzini, Diógenes Santiago Santos, Fabiana Quoos Mayer, Sandrine Vitry, Stéphanie Bigou, Jean Michel Heard, Úrsula da Silveira Matte, Roberto Giugliani · 2014 · Molecular Genetics and Metabolism
Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse
Yusuke Imagawa, Tatsuya Saitoh, Yoshihide Tsujimoto · 2016 · Nature Communications
Prostaglandin F2α-induced luteolysis involves activation of Signal transducer and activator of transcription 3 and inhibition of AKT signaling in cattle
Monique Tomazele Rovani, Gustavo Freitas Ilha, Bernardo Garziera Gasperin, Janduí Escarião da Nóbrega, Dayananda Siddappa, Werner Giehl Glanzner, Alfredo Quites Antoniazzi, Vilceu Bordignon, Raj Duggavathi, Paulo Bayard Dias Gonçalves · 2017 · Molecular Reproduction and Development
Multidimensional Imaging of Mammary Gland Development: A Window Into Breast Form and Function
Bethan Lloyd‐Lewis · 2020 · Frontiers in Cell and Developmental Biology
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Yuyi Wang, Ombretta Salvucci, Hidetaka Ohnuki, Andy D. Tran, Taekyu Ha, Jingxin Feng, Michael DiPrima, Hyeongil Kwak, Dunrui Wang, Yanlin Yu et al. · 2021 · EMBO Molecular Medicine
Early down-regulation of milk production after weaning by pup removal and prior to involution in mouse mammary glands
Takaaki Uejyo, Chinatsu Kuki, Shoko Oyama, Haruto Kumura, Ken Kobayashi · 2014 · Cell and Tissue Research
Stat5 assumes distinct functions in mammary gland development and mammary tumor formation
Vida Vafaizadeh · 2011 · Frontiers in bioscience
Stat3 Is Required to Maintain the Full Differentiation Potential of Mammary Stem Cells and the Proliferative Potential of Mammary Luminal Progenitors
Anna Dominika Staniszewska, Sara Pensa, María M. Caffarel, Lisa H. Anderson, Valeria Poli, Christine J. Watson · 2012 · PLoS ONE
Hypothyroidism advances mammary involution in lactating rats through inhibition of PRL signaling and induction of LIF/STAT3 mRNAs
Fiorella Campo Verde Arboccó, Corina Verónica Sasso, Esteban A. Actis, Rubén W. Carón, María Belén Hapon, Graciela A. Jahn · 2015 · Molecular and Cellular Endocrinology
A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects
Sooyeon Lee, Yandong Zhou, Donald L. Gill, Shannon L. Kelleher · 2018 · Scientific Reports
Multiple ways to die: Non-apoptotic forms of cell death
Yoshihide Tsujimoto · 2012 · Acta Oncologica
A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway
Robert O’Leary, James E. Reilly, Hugo H. Hanson, Semie Kang, Nicole Lou, Greg R. Phillips · 2011 · Molecular Biology of the Cell
Synergistic apoptotic response between valproic acid and fludarabine in chronic lymphocytic leukaemia (CLL) cells involves the lysosomal protease cathepsin B
J-Y Yoon, David Szwajcer, Ganchimeg Ishdorj, Pat Benjaminson, Wenyan Xiao, Rajat Kumar, James B. Johnston, Spencer Bruce Gibson · 2013 · Blood Cancer Journal
The immune environment of the mammary gland fluctuates during post-lactational regression and correlates with tumour growth rate
Jessica R. Hitchcock, Katherine Hughes, Sara Pensa, Bethan Lloyd‐Lewis, Christine J. Watson · 2022 · Development
The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland
Fabian Schuler, Florian Baumgartner, Victoria Klepsch, Martina Chamson, Elisabeth Müller‐Holzner, Christine J. Watson, Stephanie E. Oh, Lothar G. Hennighausen, Piotr Tymoszuk, Wolfgang Doppler et al. · 2015 · Cell Death and Differentiation
C1q/ TNF ‐related peptide 8 ( CTRP 8) promotes temozolomide resistance in human glioblastoma
Thatchawan Thanasupawat, Aleksandra Głogowska, Maxwell Burg, Jerry P. Krcek, Jason Beiko, Marshall W. Pitz, Guojun Zhang, Sabine Hombach‐Klonisch, Thomas C. Klonisch · 2018 · Molecular Oncology
Nuclear degradation dynamics in a nonapoptotic programmed cell death
Alla Yalonetskaya, Albert A. Mondragon, Zackary J. Hintze, Susan Holmes, Kimberly McCall · 2019 · Cell Death and Differentiation
Development and Pathology of the Equine Mammary Gland
Katherine Hughes · 2020 · Journal of Mammary Gland Biology and Neoplasia
Differential functions of calpain 1 during epithelial cell death and adipocyte differentiation in mammary gland involution
Teresa Arnandis, Ivan Ferrer Vicens, Luís Torres, Concha Garcı́a, Elena R. García–Trevijano, Rosa Zaragozá, Juan R. Vinã · 2014 · Biochemical Journal
The Wnt Signaling Landscape of Mammary Stem Cells and Breast Tumors
Caroline M. Alexander · 2017 · Progress in molecular biology and translational science
Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions
Naoya Hayakawa, Motoko Shiozaki, Masahiro Shibata, Masato Koike, Yasuo Uchiyama, Nariaki Matsuura∥, Takahiro Gotow · 2012 · European Journal of Cell Biology
Structural and functional regulation of Chlamydomonas lysosome-related organelles during environmental changes
Huan Long, Jinhua Fang, Lian Ye, Baolong Zhang, Colleen Hui, Xuan Deng, Sabeeha Merchant, Kaiyao Huang · 2023 · PLANT PHYSIOLOGY
Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids
Inger Ødum Nielsen, Knut Kristoffer Bundgaard Clemmensen, Ditte Louise Fogde, Tiina Naumanen Dietrich, Jano Dicroce Giacobini, Mesut Bilgin, Marja Jäättelä, Kenji Maeda · 2023 · Molecular Biology of the Cell
C.elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death
Yang Li, Yu Zhang, Qiwen Gan, Meng Xu, Xiao Ding, Gui‐Hua Tang, Jingjing Liang, Kai Liu, Xuezhao Liu, Xin Wang et al. · 2018 · Protein & Cell
Bazedoxifene Regulates Th17 Immune Response to Ameliorate Experimental Autoimmune myocarditis via Inhibition of STAT3 Activation
Jing Wang, Tianshu Liu, Xiongwen Chen, Qiaofeng Jin, Yihan Chen, Li Zhang, Zhengyang Han, Dandan Chen, Yuman Li, Qing Lv et al. · 2021 · Frontiers in Pharmacology
STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
Janina Remy, Benedikt Linder, Ulrike Weirauch, Bryan W. Day, Brett William Stringer, Christel C. Herold‐Mende, Achim Michael Aigner, Knut Krohn, Donat Kögel · 2022 · Cancers
Immune Cell Contribution to Mammary Gland Development
Ramiah R. Vickers, Weston W. Porter · 2024 · Journal of Mammary Gland Biology and Neoplasia
Alveolar cells in the mammary gland: lineage commitment and cell death
Christine J. Watson · 2022 · Biochemical Journal
Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats
Yueyang Liu, Xiaohang Che, Xiang‐Nan Yu, Hanxiao Shang, Peirui Cui, Xiaoxiao Fu, Xianda Lu, Yuhuan Liu, Chunfu Wu, Jingyu Yang · 2023 · Cellular and Molecular Life Sciences
The ins and outs of calcium signalling in lactation and involution: Implications for breast cancer treatment
Felicity M. Davis · 2016 · Pharmacological Research
The presence of blastocyst within the uteri facilitates lumenal epithelium transformation for implantation via upregulating lysosome proteostasis activity
Peike Wang, Shuailin Du, Chuanhui Guo, Zhangli Ni, Ziying Huang, Na Deng, Haili Bao, Wenbo Deng, Jinhua Lu, Shuangbo Kong et al. · 2023 · Autophagy
Apoptosis in Living Animals Is Assisted by Scavenger Cells and Thus May Not Mainly Go through the Cytochrome C-Caspase Pathway
Bingya Liu, Ningzhi Xu, Yan‐Gao Man, Haihong Shen, Itzhak Avital, Alexander Stojadinovic, Dezhong Joshua Liao · 2013 · Journal of Cancer
Nano-sized polystyrene plastics toxicity: Necroptosis pathway caused by autophagy blockade and lysosomal dysfunction
Haiyan Wu, Runqiu Cai, Chaoyu Zhou, Yifei Yang, Xinyuan Tian, Zhongling Zhao, Qianyu Bai, Xuejiao Qiu, Qingyi Song, Lei Zhang et al. · 2024 · NanoImpact
C/EBPβ LIP augments cell death by inducing osteoglycin
Rina Wassermann-Dozorets, Menachem Rubinstein · 2017 · Cell Death and Disease
Hesperidin Alleviates Hepatic Injury Caused by Deoxynivalenol Exposure through Activation of mTOR and AKT/GSK3β/TFEB Pathways
Xin Wang, Hao Chen, Junze Jiang, Jun Ma · 2024 · Journal of Agricultural and Food Chemistry
Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution
Hirohisa Shibayama, Tomomi M. Yamamoto, Kenzi Oshima, Tsukasa Matsuda, Daita Nadano · 2019 · DNA and Cell Biology
The Development and Survival of Thymic Epithelial Cells Require TSC1-Dependent Negative Regulation of mTORC1 Activity
Zhanfeng Liang, Qian Zhang, Zhaoqi Zhang, Lina Sun, Xue Dong, Tianxiu Li, Liang Tan, Xubiao Xie, Sun Liguang, Yong Xiang Zhao · 2021 · The Journal of Immunology
Differential effects of oleate on vascular endothelial and liver sinusoidal endothelial cells reveal its toxic features in vitro
Yana Geng, Johanna C. Arroyave-Ospina, Manon Buist‐Homan, Josée A. Plantinga, Peter Olinga, Dirk‐Jan Reijngoud, Frederike G.I. van Vilsteren, Hans Blokzijl, Jan A. A. M. Kamps, Han J. Moshage · 2023 · The Journal of Nutritional Biochemistry
The PI3K regulatory subunits p55α and p50α regulate cell death in vivo
S Pensa, Kevin Neoh, Henrike K. Resemann, Peter A. Kreuzaler, Kathrine Abell, N J Clarke, Thomas Reinheckel, C. Ronald Kahn, Christine J. Watson · 2014 · Cell Death and Differentiation
The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution
Nomeda Girnius, Yvonne J. K. Edwards, Roger J. Davis · 2018 · Cell Death and Differentiation
A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics
Olivia C. Rivera, Donna Tracy Geddes, Shiran Barber-Zucker, Raz Zarivach, Annie Gagnon, David I. Soybel, Shannon L. Kelleher · 2020 · American Journal of Physiology-Cell Physiology
Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway
Yufeng Qi, Haodong Wu, Tianru Zhu, Zitian Liu, Conghui Liu, Congzhi Yan, Zhixuan Wu, Yiying Xu, Ying Bai, Lehe Yang et al. · 2023 · Aging
From Embryogenesis to Senescence: The Role of Mammary Gland Physiology in Breast Cancer Risk
Jaida C. Lue, Derek C. Radisky · 2025 · Cancers
Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling
Theresa Casey, Aridany Suárez-Trujillo, Conor McCabe, Linda M. Beckett, Rebecca N. Klopp, Luiz F. Brito, V.M.R. Malacco, Susan Hilger, Shawn Scott Donkin, Jacquelyn P. Boerman et al. · 2021 · Physiological Genomics