Caspase 8 inhibits programmed necrosis by processing CYLD

O’Donnell, Marie Anne, Perez-Jimenez, Eva, Oberst, Andrew, Ng, Aylwin, Massoumi, Ramin, Xavier, Ramnik, Green, Douglas R., Ting, Adrian T.·2011·Nature Cell Biology

DOI 10.1038/ncb2362

Cited by (493)

Items 201–300 of 493

Sonodynamic therapy: A potential treatment for atherosclerosis
Chi Geng, Yunlong Zhang, Tesfaldet Habtemariam Hidru, Lian-Yun Zhi, Meng-Xing Tao, Lei‐Xin Zou, Chen Chen, Hui‐Hua Li, Ying Liu · 2018 · Life Sciences
c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities
Mengtao Cao, Fei Chen, Ni Xie, Meng-Yao Cao, Pengfei Chen, Qi Lou, Yanli Zhao, Chen He, Shuyuan Zhang, Xinyang Song et al. · 2018 · Cell Death and Disease
Caspase-8 promotes c-Rel–dependent inflammatory cytokine expression and resistance against Toxoplasma gondii
Alexandra A. DeLaney, Corbett T. Berry, David A. Christian, Andrew P. Hart, Elisabet Bjånes, Meghan A. Wynosky-Dolfi, Xinyuan Li, Bart Tummers, Irina A. Udalova, Youhai H. Chen et al. · 2019 · Proceedings of the National Academy of Sciences
Selective Host Cell Death by Staphylococcus aureus: A Strategy for Bacterial Persistence
Dominique M. Missiakas, Volker Winstel · 2021 · Frontiers in Immunology
Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins
Lazaros Vasilikos, Lisanne M. Spilgies, Janin Knop, Wendy Wei-Lynn Wong · 2016 · Immunology and Cell Biology
USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability
M Jeong, E-W Lee, Dawon Seong, Jinho Seo, J-H Kim, Sasker Grootjans, S-Y Kim, Peter Vandenabeele, Jaewhan Song · 2016 · Oncogene
Ischemia Reperfusion Injury Triggers TNFα Induced-Necroptosis in Rat Retina
Cho Rong Kim, Jie‐Hyun Kim, Hae-Young Lopilly Park, Chan Kee Park · 2016 · Current Eye Research
Caspases control antiviral innate immunity
Huihui Chen, Xiaohan Ning, Zhengfan Jiang · 2017 · Cellular and Molecular Immunology
Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination and diagnostics
Christian E. Demeure, Olivier Dussurget, Guillem Mas Fiol, Anne‐Sophie Le Guern, Cyril Savin, Javier Pizarro‐Cerdá · 2019 · Microbes and Infection
NF-κB and Extrinsic Cell Death Pathways – Entwined Do-or-Die Decisions for T cells
Blanchett, Sam, Boal-Carvalho, Ines, Layzell, Scott, Seddon, Benedict · 2021 · Trends in Immunology
Surviving death: emerging concepts of RIPK3 and MLKL ubiquitination in the regulation of necroptosis
Rebekka Karlowitz, Sjoerd J. L. van Wijk · 2021 · FEBS Journal
Post-translational modifications as key regulators of TNF-induced necroptosis
X Liu, F Shi, Yuanyuan Li, X Yu, Song Peng, Wenjun Li, Xiangjian Luo, Y Cao · 2016 · Cell Death and Disease
CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing
Marinella G. Callow, Colin K. Watanabe, Katherine E. Wickliffe, Russell O. Bainer, Sarah Kummerfeld, Julie Weng, Trinna L. Cuellar, Vasantharajan Janakiraman, Honglin Chen, Ben Chih et al. · 2018 · Cell Death and Disease
Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling
Maria C. Tanzer, Isabell Bludau, Che A. Stafford, Veit Hornung, Matthias Mann · 2021 · Nature Communications
Necroptosis in acute kidney injury: a shedding light
Shuo Wang, Chao Zhang, Lingli Hu, Cheng Yang · 2016 · Cell Death and Disease
Molecular mechanisms of necroptosis and relevance for neurodegenerative diseases.
2020 · International Review of Cell and Molecular Biology
Post-translational control of RIPK3 and MLKL mediated necroptotic cell death
James M. Murphy, James Edward Vince · 2015 · F1000Research
Assays for Necroptosis and Activity of RIP Kinases
Alexei Degterev, Wen Zhou, Jenny L. Maki, Junying Yuan · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
The interplay of autophagy and non-apoptotic cell death pathways
2020 · International Review of Cell and Molecular Biology
Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6
Bram J. van Raam, Dagmar E. Ehrnhoefer, Michael R. Hayden, Guy S. Salvesen · 2012 · Cell Death and Differentiation
Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
Todd Douglas, Maya Saleh · 2019 · Cell Reports
CYLD in health and disease
José Luis Marín‐Rubio, Ishier Raote, Joseph Inns, Carol Dobson‐Stone, Neil Rajan · 2023 · Disease Models & Mechanisms
Triptolide induces PANoptosis in macrophages and causes organ injury in mice
Hongrui Zhang, Yaping Li, Zijian Shi, Qi-Qi Liang, Siyuan Chen, Yi-Ping You, Yuan Tao, Rong Xu, Lihui Xu, Dong‐Yun Ouyang et al. · 2023 · APOPTOSIS
Inhibition of colon cancer growth by docosahexaenoic acid involves autocrine production of TNFα
André Flückiger, A Dumont, Valentin Dérangère, Cédric Rébé, Charlotte de Rosny, Sébastien Causse, Charles Thomas, Lionel Apétoh, Aziz Hichami, François Ghiringhelli et al. · 2016 · Oncogene
The roles of ubiquitination in extrinsic cell death pathways and its implications for therapeutics
Jinho Seo, Min Wook Kim, Kwang‐Hee Bae, Sang Chul Lee, Jaewhan Song, Eun‐Woo Lee · 2018 · Biochemical Pharmacology
Apoptotic caspase-7 activation inhibits non-canonical pyroptosis by GSDMB cleavage
Xu Li, T Y Zhang, Lulu Kang, Ruyue Xin, Minli Sun, Qianyue Chen, Jingwen Pei, Qin Chen, Xiang Gao, Zhaoyu Lin · 2023 · Cell Death and Differentiation
Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus
Soham Mitra, Tarun Keswani, Nabanita Ghosh, Suranjana Goswami, Anuradha Datta, Salomie Das, Subhajit Maity, Arindam Bhattacharyya · 2013 · Toxicology
RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation
Jerry Wong, Ricard Garcia‐Carbonell, Matija Zelic, Samuel B. Ho, Brigid Sweeney Boland, Shih-Jing Yao, Shalin A. Desai, Soumita Das, Núria Planell, Philip A. Harris et al. · 2019 · Cellular and Molecular Gastroenterology and Hepatology
The many faces of tumor necrosis factor signaling in the intestinal epithelium
Maria Eugenia Delgado, Thomas Brunner · 2019 · Genes and Immunity
Deubiquitylases in developmental ubiquitin signaling and congenital diseases
Mohammed Abul Basar, David B. Beck, Achim A Werner · 2020 · Cell Death and Differentiation
Ferroptosis, necroptosis and cuproptosis: Novel forms of regulated cell death in diabetic cardiomyopathy
Dan Ke, Zhen Zhang, Jieting Liu, Peijian Chen, Jialing Li, Xinhai Sun, Yanhui Chu, Luxin Li · 2023 · Frontiers in Cardiovascular Medicine
Targeting programmed cell death in diabetic kidney disease: from molecular mechanisms to pharmacotherapy
Fengzhao Liu, Zhenyu Yang, Jixin Li, Tao Wu, Xiangyu Li, Lijuan Zhao, Wenru Wang, Wenfei Yu, Guangheng Zhang, Yunsheng Xu · 2024 · Molecular Medicine
Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells
Takashi Kobayashi, Katarzyna Chmielarska Masoumi, Ramin Massoumi · 2014 · Oncogene
Caspase mechanisms in the regulation of inflammation
Betsaida Bibo‐Verdugo, Guy S. Salvesen · 2022 · Molecular Aspects of Medicine
Paving TRAIL’s Path with Ubiquitin
Élodie Lafont, Torsten Hartwig, Henning Walczak · 2017 · Trends in Biochemical Sciences
Execution of RIPK3-regulated necrosis
Zhenyu Cai, Zheng-gang Liu · 2014 · Molecular & Cellular Oncology
Cylindromatosis mediates neuronal cell death in vitro and in vivo
Goutham K. Ganjam, Nicole A. Terpolilli, Sebastian Diemert, Ina Eisenbach, Lena Hoffmann, C. Reuther, Christiane Herden, Joachim Roth, Nikolaus Plesnila, Carsten Culmsee · 2018 · Cell Death and Differentiation
RHIM-based protein:protein interactions in microbial defence against programmed cell death by necroptosis
Max O.D.G. Baker, Nirukshan Shanmugam, Chi L.L. Pham, Merryn Strange, Megan C. Steain, Margaret Sunde · 2018 · Seminars in Cell and Developmental Biology
Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner
Nicolas Preyat, Maxime Rossi, Jesper Kers, Liqiang Chen, John Bertin, Peter J. Gough, Alaín Le Moine, Anthony Rongvaux, Frédéric Van Gool, Oberdan Léo · 2015 · Cell Death and Differentiation
The Paracaspase MALT1
Janna Hachmann, Guy S. Salvesen · 2015 · Biochimie
Cytopathic effects: virus-modulated manifestations of innate immunity?
Vadim I. Agol · 2012 · Trends in Microbiology
Formation and removal of poly‐ubiquitin chains in the regulation of tumor necrosis factor‐induced gene activation and cell death
Sebastian Kupka, Matthias Reichert, Peter Dráber, Henning Walczak · 2016 · FEBS Journal
Endoplasmic reticulum stress-mediated cell death in cardiovascular disease
Yajuan An, Xinshuang Wang, Xiuju Guan, Peng Yuan, Yue Liu, Liping Wei, Fei Wang, Xin Qi · 2024 · Cell Stress and Chaperones
The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited
Qing Xu, Siriporn Jitkaew, Swati Choksi, Chamila Kadigamuwa, Jianhui Qu, Moran Choe, Jonathan Jang, Chengyu Liu, Zheng-gang Liu · 2017 · Nature Communications
G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
Nathaniel W. Mabe, Nina Marie G. Garcia, Shayna E. Wolery, Rachel Newcomb, Ryan C. Meingasner, Brittany A. Vilona, Ryan Lupo, Chao‐Chieh Lin, Jen‐Tsan Chi, James V. Alvarez · 2020 · Cell Reports
Mechanisms of TNF-independent RIPK3-mediated cell death
Bart Tummers, Douglas R. Green · 2022 · Biochemical Journal
Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis
Yuanyuan Yang, Yanmei Chen, Jun Hao Wu, Yueting Ren, Bo Liu, Yan Zhang, Haiyang Yu · 2023 · Phytotherapy Research
Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3
Tae‐Bong Kang, Ju-Seong Jeong, Seung‐Hoon Yang, Andrew Kovalenko, David Wallach · 2018 · Cell Death and Differentiation
Carbon Nanodots for On Demand Chemophotothermal Therapy Combination to Elicit Necroptosis: Overcoming Apoptosis Resistance in Breast Cancer Cell Lines
Aldo Nicosia, Gennara Cavallaro, Salvatore Costa, Mara Andrea Utzeri, Angela Cuttitta, Gaetano Giammona, Nicolò Mauro · 2020 · Cancers
Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
P.R. Elliott, Derek Leske, Jane L. Wagstaff, Lisa Schlicher, G. Berridge, Sarah Maslen, Frederik Timmermann, Biao Ma, Román Fischer, Stefan M.V. Freund et al. · 2021 · Cell Reports
Fueling the Flames: Mammalian Programmed Necrosis in Inflammatory Diseases
Francis Ka-Ming Chan · 2012 · Cold Spring Harbor Perspectives in Biology
Necroptosis contributes to methamphetamine-induced cytotoxicity in rat cortical neurons
Kun Xiong, Huidan Liao, Lingling Long, Yanjun Ding, Jufang Huang, Jie Yan · 2016 · Toxicology in Vitro
The serine threonine kinase RIP3: lost and found
Michael J. Morgan, You‐Sun Kim · 2015 · BMB Reports
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery
Pang Lyu, Jinming Wen, Wenshuo Zhang, Ning Liu, Iris Stolzer, Andreas Gießl, Yewei Jia, Daniele Mauro, Fulin Zhang, Francesco Ciccia et al. · 2024 · Annals of the Rheumatic Diseases
Necroptosis in cancer: insight from epigenetic, post-transcriptional and post-translational modifications
Jinxin Tang, Yan Zhuang, Yibo Zhang, Hongkun Hu, Hua Wang, Haodong Xu, Yintao Li, Chao Tu · 2025 · Journal of Hematology & Oncology
Toll-like Receptor-mediated Down-regulation of the Deubiquitinase Cylindromatosis (CYLD) Protects Macrophages from Necroptosis in Wild-derived Mice
Stephen A. Schworer, Irina Smirnova, Курбатова Ирина Валерьевна, Uliana Bagina, Maria V. Churova, Trent Fowler, Ananda L. Roy, Alexei Degterev, Alexander Poltorak · 2014 · Journal of Biological Chemistry
The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells
Pa Wu, Kejian Shi, J J An, Yali Ci, Fenfen Li, Kaiyuan Hui, Yaning Yang, Chenzhong Xu · 2014 · Cell Death and Disease
Necroptosis in Nonalcoholic Steatohepatitis
Jérémie Gautheron, M. Vucur, T. Luedde · 2015 · Cellular and Molecular Gastroenterology and Hepatology
Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury
Raji Baidya, Dorothy H. Crawford, Jérémie Gautheron, Haolu Wang, Kim R. Bridle · 2020 · International Journal of Molecular Sciences
Liver specific deletion of CYLDexon7/8 induces severe biliary damage, fibrosis and increases hepatocarcinogenesis in mice
Toni Urbanik, Regina Johanna Boger, Thomas Longerich, Katharina Becker, Karl Roland Ehrenberg, Nadine Hövelmeyer, Matthias Hahn, Marcus Schuchmann, Dirk Jäger, Ari Waisman et al. · 2012 · Journal of Hepatology
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson’s disease
Sheila K. Pirooznia, Hu Wang, Nikhil Panicker, Manoj Kumar, Stewart Neifert, Mohammad Aasif Dar, Evan Lau, Bong Gu Kang, Javier Redding‐Ochoa, Juan Carlos Troncoso et al. · 2022 · Science Advances
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
Hong Tri Tran, Tobias Kratina, Auriane Coutansais, Dominika Michalek, Benjamin M. Hogan, Kate E. Lawlor, James Edward Vince, John Silke, Najoua Lalaoui · 2024 · Cell Death and Differentiation
Novel drug discovery strategies for atherosclerosis that target necrosis and necroptosis
Isabelle Coornaert, Sam Hofmans, Lars Devisscher, Koen Augustyns, Pieter Van der Veken, Guido R.Y. De Meyer, Wim Martinet · 2018 · Expert Opinion on Drug Discovery
Implications of Necroptosis for Cardiovascular Diseases
Zhaohui Ruan, Zi-xuan Xu, Xue-yun Zhou, Xian Zhang, Lei Shang · 2019 · Current Medical Science
Caspase-8 modulates physiological and pathological angiogenesis during retina development
Nathalie Tisch, Aida Freire-Valls, Rosario Yerbes, Isidora Paredes, Silvia La Porta, Xiaohong Wang, Rosa Martín‐Pérez, Laura Castro, Wendy Wei-Lynn Wong, Leigh Coultas et al. · 2019 · Journal of Clinical Investigation
The role of necroptosis, an alternative form of cell death, in cancer therapy
Xinfang Yu, Qipan Deng, Ann M. Bode, Zigang Dong, Ya Cao · 2013 · Expert Review of Anticancer Therapy
Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death
Kumaran Sundaram, Andrew R. Mather, Subathra Marimuthu, Parag P. Shah, Ashley J. Snider, Lina Marie Obeid, Yusuf Awni Hannun, Levi J. Beverly, Leah J. Siskind · 2016 · Biochemical Journal
The regulation of necroptosis by ubiquitylation
Yiliang Chen, Wenqing Ren, Qingsong Wang, Yuan He, Dan Ma, Zhenyu Cai · 2022 · APOPTOSIS
Caspase‐9 acts as a regulator of necroptotic cell death
Tamás Molnár, Petra Pallagi, Bálint Tél, Róbert Király, Eszter Csoma, Viktória Jenei, Zsófia Varga, Péter Gogolák, Anne‐Odile Hueber, Zoltán Máté et al. · 2021 · FEBS Journal
CERKL, a Retinal Disease Gene, Encodes an mRNA-Binding Protein That Localizes in Compact and Untranslated mRNPs Associated with Microtubules
Fathinajafabadi, Alihamze, Pérez-Jiménez, Eva, Riera, Marina, Knecht, Erwin, Gonzàlez-Duarte, Roser · 2014 · PLoS ONE
Cell death in cancer
Marcus Conrad, Andreas Strasser, Philipp Jakob Jost, Junying Yuan, Feng Shao, Peter Vandenabeele, Adam Wahida · 2026 · Cell
NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death
Marie Anne O’Donnell, Adrian T. Ting · 2012 · Immunologic Research
MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A.G.M. Cillessen, Richard J. Bende, Carel J.M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren · 2023 · Blood Cancer Journal
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
Fabian Treude, Ferdinand Kappes, Dirk Fahrenkamp, Gerhard Müller‐Newen, Federico Dajas‐Bailador, Oliver Holger Krämer, Bernhard Lüscher, Jörg Hartkamp · 2014 · Oncotarget
Nuclear Expression of β-Catenin Promotes RB Stability and Resistance to TNF-Induced Apoptosis in Colon Cancer Cells
Jinbo Han, Rossana Colla Soletti, Anil Sadarangani, Priya Sridevi, Michael E. Ramirez, Lars Eckmann, Helena L. Borges, Jean Y. J. Wang · 2013 · Molecular Cancer Research
Mitochondrial orchestration of PANoptosis: mechanisms, disease pathogenesis, and emerging therapeutic frontiers
Jiale Zhang, Xiaoya Fu, Feifan Jia, Jing Yu, Jiameng Zhang, Aoxue Bai, Mengyuan Cui, Lei Zhang, Kunhou Yao · 2025 · Cell Death Discovery
H7N9 influenza A virus activation of necroptosis in human monocytes links innate and adaptive immune responses
Andrew Chak-Yiu Lee, Jinxia Zhang, Hin Chu, Can Li, Houshun Zhu, Winger W. N. Mak, Yanxia Chen, Kin‐Hang Kok, Kelvin Kai‐Wang To, Kwok‐Yung Yuen · 2019 · Cell Death and Disease
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL)
Xin Xu, Matko Kalac, Michael Markson, Mark Chan, Joshua Brody, Govind Bhagat, Rosalind L. Ang, Diana Legarda, Scott J. Justus, Feng Liu et al. · 2020 · Cell Death and Disease
RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells
Guozhu Chen, Xiang Cheng, Ming Zhao, Song Lin, Jiangyang Lu, Jiarui Kang, Xiaodan Yu · 2014 · APOPTOSIS
Regulated Cell Death Signaling Pathways and Marine Natural Products That Target Them
Esther A. Guzmán · 2019 · Marine Drugs
The flick of a switch: which death program to choose?
Peter Vandenabeele, Gerry Melino · 2012 · Cell Death and Differentiation
Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis
Ryodai Shindo, Masaki Ohmuraya, Sachiko Komazawa‐Sakon, Sanae Miyake, Yutaka Deguchi, Soh Yamazaki, Takashi Nishina, Takayuki Yoshimoto, Soichiro Kakuta, Masato Koike et al. · 2019 · iScience
Contribution of cell death signaling to blood vessel formation
Nathalie Tisch, Carmen Ruiz de Almodóvar · 2021 · Cellular and Molecular Life Sciences
Famotidine promotes inflammation by triggering cell pyroptosis in gastric cancer cells
Jin Huang, Pingsheng Fan, Miao Liu, Chengtao Weng, Gaofei Fan, Tengyue Zhang, Xiaohong Duan, Yang Wu, Lili Tang, Guohong Yang et al. · 2021 · BMC Pharmacology and Toxicology
Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK 1
Scott J. Justus, Adrian T. Ting · 2015 · Immunological Reviews
T cell–derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death
Nicholas H. Chun, Rosalind L. Ang, Mark Chan, Robert L. Fairchild, William M. Baldwin, Julian K. Horwitz, Jesse D. Gelles, Jerry E. Chipuk, Michelle A. Kelliher, Vasile I. Pavlov et al. · 2021 · JCI Insight
Developmental checkpoints guarded by regulated necrosis
Christopher P. Dillon, Bart Tummers, Katherine Baran, Douglas R. Green · 2016 · Cellular and Molecular Life Sciences
Role of Necroptosis in Intervertebral Disc Degeneration
Abdul Khaleque, Jae Hoon Kim, Byung-Jun Hwang, Jin-Kyu Kang, Meiling Quan, Young‐Yul Kim · 2023 · International Journal of Molecular Sciences
Tumor Suppressor Cylindromatosis (CYLD) Controls HIV Transcription in an NF-κB-Dependent Manner
Lara Manganaro, Lars Pache, Tobias Herrmann, John M. Marlett, Young Hwang, Jeffrey P. Murry, Lisa Miorin, Adrian T. Ting, Renate König, Adolfo García‐Sastre et al. · 2014 · Journal of Virology
Cylindromatosis—A Protective Molecule against Liver Diseases
Claus Hellerbrand, Ramin Massoumi · 2016 · Medicinal Research Reviews
SPATA2: more than a missing link
Lisa Schlicher, Prisca Brauns‐Schubert, Florian Schubert, Ulrich Maurer · 2017 · Cell Death and Differentiation
Targeting ferroptosis, pyroptosis and necroptosis for cancer immunotherapy in melanoma: mechanistic insights and clinical perspectives
Zexing Shan, Fei Liu · 2025 · Frontiers in Immunology
Single-Cell and Population-Level Analyses Using Real-Time Kinetic Labeling Couples Proliferation and Cell Death Mechanisms
Jesse D. Gelles, Jarvier N. Mohammed, LETÍCIA VITÓRIA DA SILVA SANTOS, Diana Legarda, Adrian T. Ting, Jerry E. Chipuk · 2019 · Developmental Cell
Acute lung injury: a view from the perspective of necroptosis
Jinyan Dong, Weihong Liu, Wenli Liu, Yuqi Wen, Qingkuo Liu, Hong-Tao Wang, Guo-han Xiang, Yang Liu, Hao Hao · 2024 · Inflammation Research
Elucidating the dual roles of apoptosis and necroptosis in diabetic wound healing: implications for therapeutic intervention
Xingqian Wu, Rifang Gu, Ming Tang, Xingrui Mu, Wenjie He, Xuqiang Nie · 2024 · Burns & Trauma
The role of necroptosis in neurosurgical diseases
Tianzhi Liu, Y.H. Bao, Yulu Wang, Jiyao Jiang · 2015 · Brazilian Journal of Medical and Biological Research
Deubiquitinases in cell death and inflammation
Kim Newton, Alexander D. Gitlin · 2022 · Biochemical Journal
Unwinding the modalities of necrosome activation and necroptosis machinery in neurological diseases
Rohan V. Gupta, Smita Kumari, Rahul S. Tripathi, Rashmi K. Ambasta, Pravir Kumar · 2023 · Ageing Research Reviews
Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis
Alexander J. Varshavsky · 2012 · Protein Science
Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment
Dongxu Kang, Wungki Park, Seung‐Ha Lee, Joo-Hang Kim, Jae Jin Song · 2013 · Cellular Signalling