Caspase 8 inhibits programmed necrosis by processing CYLD

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Items 101–200 of 493

  1. Role of necroptosis in the pathogenesis of solid organ injury
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  2. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes
    Kupka, Sebastian, De Miguel, Diego, Draber, Peter, Martino, Luigi, Surinova, Silvia, Rittinger, Katrin, Walczak, Henning · 2016 · Cell Reports
  3. The roles of FADD in extrinsic apoptosis and necroptosis
    Eun‐Woo Lee, Jin-Ho Seo, Man-Hyung Jeong, Sang-sik Lee, Jae-Whan Song · 2012 · BMB Reports
  4. Cell death checkpoints in the TNF pathway
    Jon Huyghe, Dario Priem, Mathieu J.M. Bertrand · 2023 · Trends in Immunology
  5. Functions of caspase 8: The identified and the mysterious
    Guy S. Salvesen, Craig Michael Walsh · 2014 · Seminars in Immunology
  6. RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage
    A-L Nugues, Hassiba El Bouazzati, Dominique Hétuin, Céline Berthon, Anne Loyens, Elisabeth Bertrand, Nathalie Jouy, Thierry Idziorek, Bruno Quesnel · 2014 · Cell Death and Disease
  7. Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells
    Muhammad Jadoon Khan, Muhammad Rizwan Alam, Markus Waldeck‐Weiermair, Felix Karsten, Lukas N. Groschner, Monika Riederer, Seth Hallström, Patrick Rockenfeller, Viktória Kónya, Ákos Heinemann et al. · 2012 · Journal of Biological Chemistry
  8. The Two Faces of Receptor Interacting Protein Kinase-1
    Ricardo Weinlich, Douglas R. Green · 2014 · Molecular Cell
  9. Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis
    Eun‐Woo Lee, Jung-Hoon Kim, Ye-Hyeon Ahn, Jinho Seo, Aram Ko, Manhyung Jeong, Seok-Jun Kim, Jae Yoon Ro, Ki-Moon Park, Han‐Woong Lee et al. · 2012 · Nature Communications
  10. An outline of necrosome triggers
    Tom Vanden Berghe, Behrouz Hassannia, Peter Vandenabeele · 2016 · Cellular and Molecular Life Sciences
  11. SPATA2 links CYLD to the TNF‐α receptor signaling complex and modulates the receptor signaling outcomes
    Sebastian Wagner, Shankha Satpathy, Petra Beli, Chunaram Choudhary · 2016 · The EMBO Journal
  12. Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis
    Thomas J. McQuade, YoungSik Cho, Francis Ka-Ming Chan · 2013 · Biochemical Journal
  13. The role of necroptosis in cancer: A double-edged sword?
    Xia Qin, Dan Ma, Yexiong Tan, Hongyang Wang, Zhenyu Cai · 2019 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  14. A long-awaited merger of the pathways mediating host defence and programmed cell death
    Julie Magarian Blander · 2014 · Nature reviews. Immunology
  15. Apoptosis Initiation Through the Cell-Extrinsic Pathway
    Pradeep M. Nair, Min Lu, Sean Petersen, Avi Ashkenazi · 2014 · Methods in enzymology on CD-ROM/Methods in enzymology
  16. Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling
    Axel Witt, Domagoj Vucic · 2017 · Cell Death and Differentiation
  17. Caspase‐8: not so silently deadly
    Rebecca Feltham, James Edward Vince, Kate E. Lawlor · 2017 · Clinical & Translational Immunology
  18. The regulation of necroptosis by post-translational modifications
    Yanxiang Meng, Jarrod John Sandow, Peter E. Czabotar, James M. Murphy · 2021 · Cell Death and Differentiation
  19. It’s All in the PAN: Crosstalk, Plasticity, Redundancies, Switches, and Interconnectedness Encompassed by PANoptosis Underlying the Totality of Cell Death-Associated Biological Effects
    Jessica M. Gullett, Rebecca E. Tweedell, Thirumala‐Devi Kanneganti · 2022 · Cells
  20. A new kind of cell suicide: mechanisms and functions of programmed necrosis
    Liming Sun, Xiaodong Wang · 2014 · Trends in Biochemical Sciences
  21. The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death
    Lafont, Elodie, Kantari‐Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen et al. · 2017 · The EMBO Journal
  22. Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives
    Chunlin Zhuang, Fen‐Er Chen · 2019 · Journal of Medicinal Chemistry
  23. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
    M. Cristina de Almagro, Tatiana Goncharov, Kim Newton, Domagoj Vucic · 2015 · Cell Death and Disease
  24. Roles of linear ubiquitinylation, a crucial regulator of NF ‐κB and cell death, in the immune system
    Katsuhiro Sasaki, Kazuhiro Iwaï · 2015 · Immunological Reviews
  25. Necroptosis: Pathway diversity and characteristics
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  27. Multitasking Kinase RIPK1 Regulates Cell Death and Inflammation
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  28. miR-874 regulates myocardial necrosis by targeting caspase-8
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  29. Cell Death and Inflammation – A Vital but Dangerous Liaison
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  30. Current translational potential and underlying molecular mechanisms of necroptosis
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  31. Deubiquitylating Enzymes in Cancer and Immunity
    Jiang Ren, Peng Yu, Sijia Liu, Ran Li, Xin Niu, Yan Chen, Zhenyu Zhang, Fangfang Zhou, Long Zhang · 2023 · Advanced Science
  32. Complex Roles of Caspases in the Pathogenesis of Inflammatory Bowel Disease
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  33. The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis
    Kenta Moriwaki, Francis Ka-Ming Chan · 2016 · International review of cytology
  34. CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
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  35. Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
    Justine E. Roderick, Nicole M. Hermance, Matija Zelic, Matthew J. Simmons, Apostolos Polykratis, Manolis Pasparakis, Michelle A. Kelliher · 2014 · Proceedings of the National Academy of Sciences
  36. TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
    Sho Morioka, Peter M. Broglie, Emily Omori, Yuka Ikeda, Giichi Takaesu, Kunihiro Matsumoto, Jun Ninomiya‐Tsuji · 2014 · The Journal of Cell Biology
  37. Mechanisms of regulation and diversification of deubiquitylating enzyme function
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  38. IAPs, regulators of innate immunity and inflammation
    Yann Estornes, Mathieu J.M. Bertrand · 2014 · Seminars in Cell and Developmental Biology
  39. Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice
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  40. CYLD-Mediated Signaling and Diseases
    Bryan James Mathis, Yimu Lai, Chen Qu, Joseph Janicki, Taixing Cui · 2014 · Current Drug Targets
  41. TRAF2 is a biologically important necroptosis suppressor
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  42. Sperm freezing damage: the role of regulated cell death
    Erhan Hai, Boyuan Li, Jian Zhang, Jiaxin Zhang · 2024 · Cell Death Discovery
  43. Optineurin in amyotrophic lateral sclerosis: Multifunctional adaptor protein at the crossroads of different neuroprotective mechanisms
    Andrea Markovinović, Raffaello Cimbro, Tereza Ljutić, Jasna Križ, Boris Rogelj, Ivana Munitić · 2017 · Progress in Neurobiology
  44. Linear ubiquitination at a glance
    Spit, Maureen, Rieser, Eva, Walczak, Henning · 2019 · Journal of Cell Science
  45. Caspase Inhibitors Protect Neurons by Enabling Selective Necroptosis of Inflamed Microglia
    Fricker, Michael, Vilalta, Anna, Tolkovsky, Aviva M., Brown, Guy C. · 2013 · Journal of Biological Chemistry
  46. Programmed Cell Death in Sepsis Associated Acute Kidney Injury
    Zhifen Wu, Junhui Deng, Hongwen Zhou, Wei Tan, Lirong Lin, Jurong Yang · 2022 · Frontiers in Medicine
  47. Dysregulation of Intestinal Epithelial Cell RIPK Pathways Promotes Chronic Inflammation in the IBD Gut
    Ricard Garcia‐Carbonell, Shih-Jing Yao, Soumita Das, Mónica Gumá · 2019 · Frontiers in Immunology
  48. A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    Jonathan Mannion, Valentina Gifford, Benjamin R. Bellenie, Winnie Fernando, Laura Ramos Garcia, Rebecca Wilson, Sidonie Wicky John, Savita Udainiya, Emmanuel Christian Patin, Crescens Tiu et al. · 2024 · Immunity
  49. Caspase-8 in inflammatory diseases: a potential therapeutic target
    Wangzheqi Zhang, Chenglong Zhu, Yan Liao, Miao Zhou, Wenyun Xu, Zui Zou · 2024 · Cellular & Molecular Biology Letters
  50. Mechanism and specificity of the human paracaspase MALT1
    Janna Hachmann, Scott J. Snipas, Bram J. van Raam, Erik M. Cancino, Emily J. Houlihan, Marcin Poręba, Paulina Kasperkiewicz, Marcin Drąg, Guy S. Salvesen · 2012 · Biochemical Journal
  51. More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling
    Nufail R. Khan, Kate E. Lawlor, James M. Murphy, James Edward Vince · 2013 · Current Opinion in Immunology
  52. Necroptosis Mediates TNF-Induced Toxicity of Hippocampal Neurons
    Shan Liu, Xing Wang, Yun Li, Lei Xu, Xiaoliang Yu, Lin Ge, Jun Li, Yongjin Zhu, Sudan He · 2014 · BioMed Research International
  53. Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy
    Mao-Bin Meng, Huan-Huan Wang, Yao-Li Cui, Zhi-Qiang Wu, Yangyang Shi, Nicholas George Zaorsky, Lei Deng, Zhiyong Yuan, You Lü, Ping Wang · 2016 · Oncotarget
  54. Cell death in drug-induced liver injury
    Andrea Iorga, Lily Dara · 2019 · Advances in pharmacology
  55. Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
    Ruoshi Peng, Chris Kedong Wang, Xuan Wang‐Kan, Manja Idorn, Majken Kjær, Felix Zhou, Berthe Katrine Fiil, Frederik Timmermann, Susana L. Orozco, Julia McCarthy et al. · 2022 · EMBO Reports
  56. Necroptosis and neutrophil-associated disorders
    Xiaoliang Wang, Shída Yousefi, Hans‐Uwe Simon · 2018 · Cell Death and Disease
  57. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
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  58. Necroptosis: A new way of dying?
    Britt Hanson · 2016 · Cancer Biology & Therapy
  59. Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils
    Simone Wicki, Ursina Gurzeler, Wendy Wei-Lynn Wong, Philipp Jakob Jost, Daniel Bachmann, Thomas Kaufmann · 2016 · Cell Death and Disease
  60. Cell death signalling in virus infection
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  61. Cell death‐independent activities of the death receptors CD 95, TRAILR 1, and TRAILR 2
    Daniela Siegmund, Isabell Lang, Harald Wajant · 2016 · FEBS Journal
  62. Insane in the membrane: a structural perspective of MLKL function in necroptosis
    Emma J. Petrie, Joanne M. Hildebrand, James M. Murphy · 2016 · Immunology and Cell Biology
  63. Programmed necrosis and autophagy in immune function
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  64. pH-responsive aminotriazole doped metal organic frameworks nanoplatform enables self‐boosting reactive oxygen species generation through regulating the activity of catalase for targeted chemo/chemodynamic combination therapy
    Jun-Liang Dong, Yueyuan Yu, Yuxin Pei, Zhichao Pei · 2021 · Journal of Colloid and Interface Science
  65. cFLIP Regulates Skin Homeostasis and Protects against TNF-Induced Keratinocyte Apoptosis
    Diana Panayotova‐Dimitrova, Maria Feoktistova, Michaela Ploesser, Beate Kellert, Mike Hupe, Sebastian Horn, Román Makarov, Federico Jensen, Štefan Porubský, Astrid Schmieder et al. · 2013 · Cell Reports
  66. Cell death in head and neck cancer pathogenesis and treatment
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  67. Hyperglycemic Conditions Prime Cells for RIP1-dependent Necroptosis
    Timothy J. LaRocca, Sergey A. Sosunov, Nicole L. Shakerley, Vadim S. Ten, Adam J. Ratner · 2016 · Journal of Biological Chemistry
  68. Caspases in metabolic disease and their therapeutic potential
    Claire H. Wilson, Sharad Kumar · 2018 · Cell Death and Differentiation
  69. Therapeutic hypothermia attenuates tissue damage and cytokine expression after traumatic brain injury by inhibiting necroptosis in the rat
    Tao Liu, Dong-xu Zhao, Hua Cui, Lei Chen, Yinghui Bao, Yong Wang, Jiyao Jiang · 2016 · Scientific Reports
  70. Cell Death and Liver Disease
    Satoka Aizawa, Gurmehr Brar, Hidekazu Tsukamoto · 2019 · Gut and Liver
  71. USP22 controls necroptosis by regulating receptor-interacting protein kinase 3 ubiquitination
    Jens Roedig, Lisa Kowald, Thomas Juretschke, Rebekka Karlowitz, Behnaz Ahangarian Abhari, Heiko Roedig, Simone Fulda, Petra Beli, Sjoerd J. L. van Wijk · 2020 · EMBO Reports
  72. The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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  73. New components of the necroptotic pathway
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  75. Reactive Oxygen Species: A Double-Edged Sword in the Modulation of Cancer Signaling Pathway Dynamics
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