Chemical phylogenetics of histone deacetylases

Cited by (769)

Items 501–600 of 769

1. Chemical Tools for Probing Histone Deacetylase (HDAC) Activity
   Masafumi Minoshima, Kazuya Kikuchi · 2015 · Analytical Sciences
2. Design and development of histone deacetylase (HDAC) chemical probes for cell-based profiling
   Victoria E. Albrow, Rachel L. Grimley, James A. Clulow, Colin R. Rose, Jianmin Sun, Joseph S. Warmus, Edward W. Tate, Lyn H. Jones, R. Ian Storer · 2016 · Molecular BioSystems
3. Pruritus Reduction with Systemic Anti-lymphoma Treatments in Patients with Cutaneous T Cell Lymphoma: A Narrative Review
   Halle Field, Ling Gao, Pooja Motwani, Henry K. Wong · 2016 · Dermatology and Therapy
4. Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes
   Weston W. Blakeslee, Ying‐Hsi Lin, Matthew S. Stratton, Philip D. Tatman, Tianjing Hu, Bradley S. Ferguson, Timothy A. McKinsey · 2017 · Journal of Molecular and Cellular Cardiology
5. Epigenetic approaches to cancer therapy
   Roy M. Pollock, Victoria M. Richon · 2009 · Drug Discovery Today Therapeutic Strategies
6. Intrinsic Dynamics of the Binding Rail and Its Allosteric Effect in the Class I Histone Deacetylases
   Jingwei Zhou, Yue Huang, Chunyan Cheng, Kai Wang, Ruibo Wu · 2017 · Journal of Chemical Information and Modeling
7. HDACs and Their Inhibitors on Post-Translational Modifications: The Regulation of Cardiovascular Disease
   Siyi Yang, Yidong Sun, Wei Yu · 2025 · Cells
8. Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase Inhibitors by Multimodality Molecular Imaging in Living Subjects
   Carmel T. Chan, Jun Qi, W. Smith, R. Paranol, Ralph Mazitschek, Nathan H. West, Robert E. Reeves, Gabriela Chiosis, Stuart L. Schreiber, James E. Bradner et al. · 2014 · Cancer Research
9. Continuous Sirtuin/HDAC (histone deacetylase) activity assay using thioamides as PET (Photoinduced Electron Transfer)–based fluorescence quencher
   Matthes Zessin, Marat Meleshin, Zeljko Simic, Diana Kalbas, Miriam Arbach, Philip Gebhardt, Jelena Melesina, Sandra Liebscher, Frank Bordusa, Wolfgang Sippl et al. · 2021 · Bioorganic Chemistry
10. Design and Synthesis of Novel Uracil-Linked Schiff Bases As Dual Histone Deacetylase Type II/topoisomerase Type I Inhibitors With Apoptotic Potential
    Samar A. El-Kalyoubi, Samar S. Elbaramawi, Ahmed G. Eissa, Essam Al Ageeli, Yahya Hasan Hobani, Aya Ali El-Sharkawy, Hossam Taha Mohamed, Ahmed Ali Al-Karmalawy, Hamada S. Abulkhair · 2023 · Future Medicinal Chemistry
11. Epigenetics and the Environment: In Search of the “Toleroasome” Vital to Execution of Ischemic Preconditioning
    David Brand, Rajiv R. Ratan · 2013 · Translational Stroke Research
12. Promiscuous actions of small molecule inhibitors of the protein kinase D‐class IIa HDAC axis in striated muscle
    Douglas D. Lemon, Brooke C. Harrison, Todd R. Horn, Matthew S. Stratton, Bradley S. Ferguson, Michael F. Wempe, Timothy A. McKinsey · 2015 · FEBS Letters
13. Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases
    Leonhard M. Henkes, Patricia Haus, Felix Jäger, Joachim Ludwig, Franz‐Josef Meyer‐Almes · 2011 · Bioorganic & Medicinal Chemistry
14. Profiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitors
    Daiqing Liao · 2015 · Drug Discovery Today Technologies
15. HDAC1/2‐mediated regulation of JNK and ERK phosphorylation in bovine mammary epithelial cells in response to TNF‐α
    Samantha Romanick, Kristen Morrill, Andrew Hostler, Levi W. Evans, Yiqiu Shen, Allison Matsumura, Haleigh Piotrowski, Lorrayny Galoro da Silva, Antonio Pinheiro Faciola, Bradley S. Ferguson · 2018 · Journal of Cellular Physiology
16. Inhibition of Histone Deacetylases
    Cheng Liu, Dawei Xu · 2004 · Humana Press eBooks
17. A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development
    Steve Alexander, Jane F Armstrong, Anthony P. Davenport, Jamie A. Davies, Elena Faccenda, Simon D Harding, Francesca Levi‐Schaffer, Adam J Pawson, Christopher Southan, Michael Spedding · 2020
18. Royaume du Maroc
    Benhima · 1962 · Présence Africaine
19. The black sheep of class IIa: HDAC7 SIKens the heart
    Joshua G. Travers, Tianjing Hu, Timothy A. McKinsey · 2020 · Journal of Clinical Investigation
20. Spatial and temporal dynamics of HDACs class IIa following mild traumatic brain injury in adult rats
    Swatabdi Kamal, Shreya Potukutchi, David J. Gelovani, Robin E. Bonomi, Srinivasu Kallakuri, John M. Cavanaugh, Thomas J. Mangner, Alana C. Conti, Ren-Shyan Liu, Renata Pasqualini et al. · 2022 · Molecular Psychiatry
21. Novel histone deacetylase 6 inhibitors using benzimidazole as caps for cancer treatment
    Phuong Hong Nguyen, Bùi Thị Bửu Huê, Phạm Minh Quân, Tran Phuong Hoa, Quang De Tran, Hosun Jung, Le Trong Hieu, Cường Quốc Nguyễn, Vinh Quang Hong, Nguyen Phu Quy et al. · 2023 · New Journal of Chemistry
22. Fragment-Based Drug Design of Selective HDAC6 Inhibitors
    Dušan Ružić, Nemanja Djoković, Katarina M. Nikolic · 2021 · Methods in molecular biology
23. Characterization of the class IIa histone deacetylases substrate specificity
    Zsófia Kutil, Marat Meleshin, Petra Baranova, Barbora Havlinova, Mike Schutkowski, Cyril Bařinka · 2022 · The FASEB Journal
24. Romidepsin in the Treatment of T-Cell Lymphoma†
    Lily P H Yang · 2011 · BioDrugs
25. Serendipitous discovery of potent human head and neck squamous cell carcinoma anti-cancer molecules: A fortunate failure of a rational molecular design
    Chiara Zagni, Venerando Pistarà, Luciana A. Oliveira, ROGERIO MORAES CASTILHO, Giovanni Romeo, Ugo Chiacchio, Antonio Rescifina · 2017 · European Journal of Medicinal Chemistry
26. Synthesis and biological evaluation of Santacruzamate-A based analogues
    Rosario Randino, Patrizia Gazzerro, Ralph Mazitschek, Manuela Rodriquez · 2017 · Bioorganic & Medicinal Chemistry
27. Prediction of Protein Acetylation Sites using Kernel Naive Bayes Classifier Based on Protein Sequences Profiling
    Shakil Ahmed, Md. Shahjaman, Enamul Kabir, Md. Kamruzzaman · 2018 · Bioinformation
28. Differential modulation of GR signaling and HDACs in the development of resilient/vulnerable phenotype and antidepressant-like response of vorinostat
    K V Athira, Abhipradnya Bipin Wahul, Kalyani Soren, Tapatee Das, Sandeep Kumar Dey, Pavan Kumar Samudrala, Arvind Kumar, Mangala Lahkar, Sumana Chakravarty · 2020 · Psychoneuroendocrinology
29. Acetylation of Endogenous STAT Proteins
    Torsten Ginter, Thorsten Heinzel, Oliver Holger Krämer · 2012 · Methods in molecular biology
30. An Olefin Cross-Metathesis Approach to Depudecin and Stereoisomeric Analogues.
    Iván Cheng-Sánchez, Cristina García-Ruiz, Guillermo A. Guerrero-Vásquez, F. Sarabia · 2017 · Journal of Organic Chemistry
31. Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase
    Takeshi Harada, Hiroto Ohguchi, Asuka Oda, Michiyasu Nakao, Jumpei Teramachi, Masahiro Hiasa, Ryohei Sumitani, Masahiro Oura, Kimiko Sogabe, Tomoko Maruhashi et al. · 2022 · Blood Advances
32. First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease
    Alan Santini, Elisa Tassinari, Eleonora Poeta, Manuela Loi, Elisabetta Ciani, Stefania Trazzi, Rebecca Piccarducci, Simona Daniele, Claudia Martini, Barbara Pagliarani et al. · 2024 · ACS Chemical Neuroscience
33. Human neuronal cells: epigenetic aspects
    Jessica Kukucka, Tessa Wyllie, Justin L. Read, Lauren Mahoney, Cenk Suphioglu · 2013 · BioMolecular Concepts
34. Tiny Titans: Nanobodies as Powerful Tools for TR‐FRET Assay Development
    N. Connor Payne, Ralph Mazitschek · 2022 · Analysis & Sensing
35. CRISPR-Cas9-mediated gene therapy in lung cancer
    Hossein Kazemizadeh, Alireza Kashefizadeh · 2022 · Clinical & Translational Oncology
36. Targeting components of epigenome by small molecules
    Jueng Soo You, Jeong Hwan Han · 2014 · Archives of Pharmacal Research
37. Phage‐assisted , active site‐directed ligand evolution of a potent and selective histone deacetylase 8 inhibitor
    Jared S. Morse, Yan J. Sheng, Joshua Trae Hampton, Lauralee D. Sylvain, Sukant Kishore Das, Yugendar R. Alugubelli, Peng‐Hsun Chase Chen, Kai S. Yang, Shiqing Xu, Carol A. Fierke et al. · 2022 · Protein Science
38. Animal Models of Epigenetic Regulation in Neuropsychiatric Disorders
    C. Bountra, Udo C. T. Oppermann, Tom D. Heightman · 2011 · Current topics in behavioral neurosciences
39. Romidepsin: A Guide to its Clinical Use in Cutaneous T-Cell Lymphoma
    Katherine Ann Lyseng-Williamson, Lily P H Yang · 2011 · American Journal of Clinical Dermatology
40. Trends in the treatment of cutaneous T-cell lymphoma – critical evaluation and perspectives on vorinostat
    Chunlei Zhang, Rangwala, Madeleine A. Duvic · 2012 · Blood and Lymphatic Cancer Targets and Therapy
41. Environment-sensitive fluorescent inhibitors of histone deacetylase
    Xin Zhou, Gaopan Dong, Tian-Jia Song, Guankai Wang, Zhenzhen Li, Xiaojun Qin, Lüpei Du, Minyong Li · 2020 · Bioorganic & Medicinal Chemistry Letters
42. Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts
    Dana L. Cruz, Nina H. Pipalia, Shu Mao, Deepti Gadi, Gang Liu, Michael Grigalunas, Matthew J. O’Neill, Taylor R. Quinn, Andi Kipper, Andreas Ekebergh et al. · 2021 · ACS Pharmacology & Translational Science
43. HDACs in Skeletal Muscle Remodeling and Neuromuscular Disease
    Bryan J. Simmons, Todd J. Cohen, Richard Bedlack, Tso‐Pang Yao · 2011 · Handbook of experimental pharmacology
44. A novel method for purification of polymerizable tubulin with a high content of the acetylated isotype
    Agustín Carbajal, Maria Eugenia Chesta, C. Gastón Bisig, Carlos A. Arce · 2012 · Biochemical Journal
45. Histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits anti-inflammatory activities through induction of mitochondrial damage and apoptosis in activated lymphocytes
    Zijian Shi, Dong‐Yun Ouyang, Jun-Shan Zhu, Lihui Xu, Xian‐Hui He · 2012 · International Immunopharmacology
46. Class IIa HDACs Are Important Signal Transducers with Unclear Enzymatic Activities
    Claudio Brancolini · 2025 · Biomolecules
47. Proteasome Cap Targeting Chimeras for Ubiquitination‐Independent Targeted Protein Degradation
    Chen Song, Qi Liu, Tingjian Wang, Yan Y. Song, Logan H. Sigua, Paul M.C. Park, Scott B. Ficarro, Sunwoo Liv Lee, S. Picaud, P. Filippakopoulos et al. · 2026 · Angewandte Chemie International Edition
48. In-silico discovery of dual active molecule to restore synaptic wiring against autism spectrum disorder via HDAC2 and H3R inhibition
    Anupam Raja, Nishant Shekhar, Harvinder Singh, Ajay Prakash, Bikash Medhi · 2022 · PLoS ONE
49. Exploring epigenetic strategies for the treatment of osteoporosis
    Sun-Ju Yi, Jaeho Lim, Kyunghwan Kim · 2024 · Molecular Biology Reports
50. Histone Deacetylase Inhibitors in Medical Therapeutics
    Pusoon Chun · 2016 · Elsevier eBooks
51. Regulation of gene expression in ischemic preconditioning in the brain.
    Tuo Yang, Qianqian Li, Feng Zhang · 2017 · PubMed
52. Promising Chemotherapy for Malignant Pediatric Brain Tumor in Recent Biological Insights
    Qian Zhou, Yichen Xu, Yan Zhou, Jincheng Wang · 2022 · Molecules
53. Entinostat finds a path: A new study elucidates effects of the histone deacetylase inhibitor on the immune system
    Ira Surolia, Susan Elaine Bates · 2018 · Cancer
54. A sensitive protein-based sensor for quantifying histone acetylation levels
    Oscar Fernando Sánchez, Drew Williamson, Lutong Cai, Chongli Yuan · 2015 · Talanta
55. Enhancing HDAC Inhibitor Screening: Addressing Zinc Parameterization and Ligand Protonation in Docking Studies
    Rocco Buccheri, Alessandro Coco, Lorella Pasquinucci, Emanuele Amata, Agostino Marrazzo, Antonio Rescifina · 2025 · International Journal of Molecular Sciences
56. Additional possibilities of chimeric antigen receptor T-cells in B-cell lymphoma: combination therapy
    Yan Yang, Jing Zhou, Cong Cao, Panpan Cai, Xinxuan Wang, Chun Chang, Jingxuan Wang, Qingyuan Zhang · 2020 · Translational Cancer Research
57. A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma
    Stephen W. Booth, Toby Andrew Eyre, John A. Whittaker, Leticia Campo, Lai Mun Wang, Elizabeth J. Soilleux, Daniel J. Royston, Gabrielle Rees, Murali Kesavan, Catherine Hildyard et al. · 2021 · BMC Cancer
58. Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat
    Ryan R. G. Barrett, Claire E. Nash, Marine Diennet, David Cotnoir‐White, Christopher Doyle, Sylvie Mader, Axel A. Thomson, James L. Gleason · 2021 · Bioorganic & Medicinal Chemistry Letters
59. Romidepsin in relapsed/refractory T-cell lymphomas: Italian experience and results of a named patient program
    Pier Luigi Zinzani, Cinzia Pellegrini, Giuseppe Cerciello, Federico Monaco, Stefano Volpetti, Annalisa Peli, Emanuele Angelucci, Paolo Corradini, Maria Christina Cox, Attilio Guarini et al. · 2016 · Leukemia & lymphoma/Leukemia and lymphoma
60. The triumph of chemically enhanced cellular reprogramming: a patent review
    Muhammad Ayaz Anwar, Songmee Kim, Sangdun Choi · 2015 · Expert Opinion on Therapeutic Patents
61. Light-Trigerred Cellular Epigenetic Molecule Release To Reverse Tumor Multidrug Resistance
    Leilei Shi, Li Xu, Qinghua Guan, Xin Jin, Jiapei Yang, Xinyuan Zhu · 2018 · Bioconjugate Chemistry
62. The Emerging Role of Histone Deacetylases (HDACs) in UPR Regulation
    Soumen Kahali, Bhaswati Sarcar, Prakash Chinnaiyan · 2011 · Methods in enzymology on CD-ROM/Methods in enzymology
63. Long-Term Treatment with Romidepsin in Patients with Peripheral T-Cell Lymphoma
    Claudius Irlé, Jonathan Weintraub · 2016 · Case Reports in Hematology
64. Epigenetic Therapies
    Wallace Bourgeois, Scott A. Armstrong, Emily Heikamp · 2024 · Cold Spring Harbor Perspectives in Medicine
65. Scaffolding Activities of Pseudodeacetylase HDAC7
    Ishadi K. M. Kodikara, Mary Kay H. Pflum · 2025 · ACS Chemical Biology
66. Dihydropyrazole-Carbohydrazide Derivatives with Dual Activity as Antioxidant and Anti-Proliferative Drugs on Breast Cancer Targeting the HDAC6
    Irving Balbuena-Rebolledo, Astrid M. Rivera-Antonio, Yudibeth Sixto‐López, José Correa‐Basurto, Martha Cecilia Rosales‐Hernández, Jessica Elena Mendieta‐Wejebe, Francisco J. Martı́nez-Martı́nez, Ivonne María Olivares-Corichi, José Rubén García-Sánchez, Juan Alberto Guevara‐Salazar et al. · 2022 · Pharmaceuticals
67. Molecular perspectives in hypertrophic heart disease: An epigenetic approach from chromatin modification
    Fernando Lizcano, Lizeth Bustamante · 2022 · Frontiers in Cell and Developmental Biology
68. Differences in Functional Expression of Connexin43 and NaV1.5 by Pan- and Class-Selective Histone Deacetylase Inhibition in Heart
    Xian Zhang, Dakshesh Patel, Qin Xu, Richard D. Veenstra · 2018 · International Journal of Molecular Sciences
69. Design and Synthesis of a Tetrahydroisoquinoline‐Based Hydroxamate Derivative ( ZYJ ‐34v), An Oral Active Histone Deacetylase Inhibitor with Potent Antitumor Activity
    Yingjie Zhang, Chunxi Liu, C. James Chou, Xuejian Wang, Yuping Jia, Wenfang Xu · 2013 · Chemical Biology & Drug Design
70. FASIL-MS: An Integrated Proteomic and Bioinformatic Workflow To Universally Quantitate In Vivo-Acetylated Positional Isomers
    Dijana Vitko, Peter Májek, Erika Schirghuber, Stefan Kubicek, Keiryn L. Bennett · 2016 · Journal of Proteome Research
71. Inhibition of Histone Deacetylases
    Yi Huang, Patrick G. Shaw, Nancy E. Davidson · 2011 · Methods in molecular biology
72. Proteolysis-Targeting Chimeras (PROTACs) Based on Macrocyclic Tetrapeptides Selectively Degrade Class I Histone Deacetylases 1–3
    Martin Roatsch, Anja Vogelmann, Daniel Herp, Manfred Jung, Christian Adam Olsen · 2020 · ChemRxiv
73. Class I HDAC inhibitors attenuate dexamethasone-induced muscle atrophy via increased protein kinase C (PKC) delta phosphorylation
    Justine S. Habibian, Matthew J. Bolino, Anthony Qian, Rebekah J. Woolsey, David R. Quilici, Juli Petereit, Bradley S. Ferguson · 2023 · Cellular Signalling
74. MSTL-Kace: Prediction of Prokaryotic Lysine Acetylation Sites Based on Multistage Transfer Learning Strategy
    Gang-Ao Wang, Xiaodi Yan, Xiang Li, Yinbo Liu, Junfeng Xia, Xiaolei Zhu · 2023 · ACS Omega
75. Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer
    Louise Walsh, William M. Gallagher, Darran P. O’Connor, Tríona Ní Chonghaile · 2016 · Expert Review of Molecular Diagnostics
76. Histone modification as a potential preventative and therapeutic approach for cardiovascular disease
    Justine S. Habibian, Bradley S. Ferguson · 2020 · Elsevier eBooks
77. HDAC8 regulates protein kinase D phosphorylation in skeletal myoblasts in response to stress signaling
    Justine S. Habibian, Matthew J. Bolino, Bradley S. Ferguson · 2023 · Biochemical and Biophysical Research Communications
78. Current status of histone deacetylase inhibitors in cutaneous T-cell lymphoma
    Megan H. Trager, Larisa J. Geskin · 2019 · Giornale Italiano di Dermatologia e Venereologia
79. Treatment of autoimmune encephalomyelitis with a histone deacetylase inhibitor: Analyzing the role of immune-response genes
    Arathi K. Jayaraman, Karen Avgush, Rashad Kulam, Soni, Advait, Areeb Khan, Mourad Kerdjoudj, Sundararajan Jayaraman · 2020 · Free Neuropathology
80. Quantitative Sub-Cellular Acyl-Coa Analysis Reveals Distinct Nuclear Regulation
    Sophie Trefely, Katharina Huber, Joyce Liu, Michael Noji, Stephanie Stransky, Jay Prakash Singh, Mary T. Doan, Claudia D. Lovell, Eliana V. von Krusenstiern, Helen Jiang et al. · 2021 · SSRN Electronic Journal
81. Histone deacetylase inhibition expands cellular proteostasis repertoires to enhance neuronal stress resilience
    Caitlin Ann Taylor, Maya Maor-Nof, Wendy A. Herbst, Shihong Max Gao, Xinyue Li, Eyal Metzl-Raz, Aaron Hidalgo, Faria Zafar, Callista Stephanie Yee, Birgitt Schüle et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
82. Selective HDAC6 inhibition by Mesinostat impairs tumor growth and stemness in triple-negative breast cancer
    Ivana Bello, Simona Barone, Anna Guadagni, Camilla Esposito, Morena D'Ariano, Martina Smimmo, Giuseppe Cirino, Vincenzo Summa, Margherita Brindisi, Elisabetta Panza · 2025 · Pharmacological Research
83. Design, synthesis and antiproliferative activity of raloxifene/histone deacetylase inhibitor hybrids in breast cancer
    Yufei Wang, Madline Sauvage, Marine Diennet, Sandra Weber, Sylvie Mader, James L. Gleason · 2024 · European Journal of Medicinal Chemistry
84. New potent N‐hydroxycinnamamide‐based histone deacetylase inhibitors suppress proliferation and trigger apoptosis in THP‐1 leukaemia cells
    Magdalena Onuščáková, Tereza Kauerová, Eva Fialova, Hana Pížová, Vladimír Garaj, Miroslav Kemka, Vladimı́r Frecer, Péter Kollár, Pavel Bobáľ · 2025 · Archiv der Pharmazie
85. Nanoromidepsin, a polymer nanoparticle of the HDAC inhibitor, improves safety and efficacy in models of T-cell lymphoma
    Ipsita Pal, Anuradha Illendula, Andrea Joyner, John Sanil Manavalan, Tess M. Deddens, Ariana Sabzevari, Deepthi Priyanka Damera, Samir Zuberi, Enrica Marchi, Todd E. Fox et al. · 2025 · Blood
86. Purification and enzymatic assay of class I histone deacetylase enzymes
    Mark K. Adams, Charles A.S. Banks, Sayem Miah, Maxime Killer, Michael P. Washburn · 2019 · Methods in enzymology on CD-ROM/Methods in enzymology
87. Revealing chromatin-specific functions of histone deacylases
    Carlos Moreno–Yruela, Beat Fierz · 2024 · Biochemical Society Transactions
88. Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors
    Tobias N. Hansen, Daniela Danková, Michael Bæk, Linda Grlaš, Christian Adam Olsen · 2024 · JACS Au
89. An acetylation photoswitch
    Andreas S. Madsen, Christian Adam Olsen · 2016 · Nature Chemical Biology
90. α,ß-Didehydrosuberoylanilide hydroxamic acid (DDSAHA) as precursor and possible analogue of the anticancer drug SAHA
    Shital Kumar Chattopadhyay, Subhankar Ghosh, Sarita Sarkar, Kakali Bhadra · 2019 · Beilstein Journal of Organic Chemistry · Retracted
91. Present and future perspectives for targeting histone modifications in therapy
    Vânia Camilo, Cármen Jerónimo · 2020 · Elsevier eBooks
92. Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibitors
    Yunhong Nong, Yanyan Hou, Yuting Pu, Si Li, Yan Lan · 2021 · SLAS DISCOVERY
93. Romidepsin (Istodax® for intravenous injection 10 mg): pharmacokinetics, pharmacodynamics and clinical study outcome
    Tokihiro Ro, Naoki Nakayama, Hiroyuki Achiwa, Tomoko Ohtsu · 2018 · Folia Pharmacologica Japonica
94. De-mystifying the Epigenetic Free for All: Pharmacophore Modeling for Epigenetic Cancer Therapy
    Viviane Rösner de Almeida, Algemir Lunardi Brunetto, Gilberto Schwartsmann, Rafael Roesler, Ana Lúcia Abujamra · 2011 · Pharmaceutica Analytica Acta
95. Target deconvolution of HDAC pharmacopoeia highlights MBLAC2 as common off-target
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96. PROTACs improve selectivity for targeted proteins
    Lihua Liu, Xian Guan, Jiezhen Zhuo, Xifeng Wu, Xin Han · 2025 · Acta Materia Medica
97. Target Engagement Studies and Kinetic Live-Cell Degradation Assays Enable the Systematic Characterization of Histone Deacetylase 6 Degraders
    Maria Hanl, Felix Feller, Irina Honin, Kathrin Tan, Martina Miranda, Linda Schäker‐Hübner, Nico Bückreiß, Matthias Schiedel, Michael Gütschow, Gerd Bendas et al. · 2025 · ACS Pharmacology & Translational Science
98. Discovery of Histone Deacetylase 8-Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies
    Shiyang Zhai, Marie Kemkes, Cindy-Esther Kponomaizoun, Jan Gerhartz, Felix Feller, Jia‐Wey Tu, Dominika Ewa Pieńkowska, Julian Schliehe‐Diecks, Ina Dressel, Michael Gütschow et al. · 2026 · Journal of Medicinal Chemistry
99. CC1007, a small molecular compound, suppresses multiple myeloma via upregulation of Nur77
    Shicong Zhu, Cheng Xing, Guangsen Zhang, Hongling Peng, Zhihua Wang · 2022 · Bioorganic Chemistry
100. Nitrilase mediated mild hydrolysis of a carbon‐14 nitrile for the radiosynthesis of 4‐(7‐hydroxycarbamoyl‐[1‐14C‐heptanoyl]‐oxy)‐benzoic acid methyl ester, [14C]‐SHP‐141: A novel class I/II histone deacetylase (HDAC) inhibitor
     Sean L. Kitson, William H. Watters, Thomas S. Moody, Todd Chappell, Ralph Mazitschek · 2023 · Journal of Labelled Compounds and Radiopharmaceuticals