Network-based in silico drug efficacy screening

Guney, Emre, Menche, Jörg, Vidal, Marc, Barábasi, Albert-László·2016·Nature Communications

DOI 10.1038/ncomms10331

Cited by (643)

Items 301–400 of 643

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Yu Ding, Hong Wang, Hewei Zheng, Lianzong Wang, Guosi Zhang, Jiaxin Yang, Xiaoyan Lu, Yu Bai, Haotian Zhang, Jing Li et al. · 2019 · Briefings in Bioinformatics
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