The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A single generation of domestication heritably alters the expression of hundreds of genes
Open accessAbstract
The genetic underpinnings associated with the earliest stages of plant and animal domestication have remained elusive. Because a genome-wide response to selection can take many generations, the earliest detectable changes associated with domestication may first manifest as heritable changes to global patterns of gene expression. Here, to test this hypothesis, we measured differential gene expression in the offspring of wild and first-generation hatchery steelhead trout (Oncorhynchus mykiss) reared in a common environment. Remarkably, we find that there were 723 genes differentially expressed between the two groups of offspring. Reciprocal crosses reveal that the differentially expressed genes could not be explained by maternal effects or by chance differences in the background levels of gene expression among unrelated families. Gene-enrichment analyses reveal that adaptation to the novel hatchery environment involved responses in wound healing, immunity and metabolism. These findings suggest that the earliest stages of domestication may involve adaptation to highly crowded conditions.
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Cites
Cis-regulatory elements: Molecular mechanisms and evolutionary processes underlying divergence
Wittkopp, P. J., & Kalay, G. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3095 · Cited by 1,231
Whole-genome resequencing reveals loci under selection during chicken domestication
Rubin, C.-J., Zody, M. C., Eriksson, J., Meadows, J. R. S., Sherwood, E., Webster, M. T., Jiang, L., Ingman, M., Sharpe, T., Ka, S., et al. (2010) · Nature · doi:10.1038/nature08832 · Cited by 1,138
The genomic signature of dog domestication reveals adaptation to a starch-rich diet
Axelsson, E., Ratnakumar, A., Arendt, M.-L., Maqbool, K., Webster, M. T., Perloski, M., Liberg, O., Arnemo, J. M., Hedhammar, Å., & Lindblad-Toh, K. (2013) · Nature · doi:10.1038/nature11837 · Cited by 963
Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication
Carneiro, M., Rubin, C.-J., Di Palma, F., Albert, F. W., Alföldi, J., Barrio, A. M., Pielberg, G., Rafati, N., Sayyab, S., Turner-Maier, J., et al. (2014) · Science · doi:10.1126/science.1253714 · Cited by 404
Montague, M. J., Li, G., Gandolfi, B., Khan, R., Aken, B. L., Searle, S. M. J., Minx, P., Hillier, L. W., Koboldt, D. C., Davis, B. W., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410083111 · Cited by 340
Cited by
Glover, K. A., Solberg, M. F., McGinnity, P., Hindar, K., Verspoor, E., Coulson, M. W., Hansen, M. M., Araki, H., Skaala, Ø., & Svåsand, T. (2017) · Fish and Fisheries · doi:10.1111/faf.12214 · Cited by 363
Next-generation data filtering in the genomics era
Hemstrom, W., Grummer, J. A., Luikart, G., & Christie, M. R. (2024) · Nature Reviews Genetics · doi:10.1038/s41576-024-00738-6 · Cited by 77
Self-citationWildlife Conservation: Is Domestication a Solution?
Teletchea, F. (2017) · Global Exposition of Wildlife Management · doi:10.5772/65660 · Cited by 23
Metadata
- Authors
- Christie, M. R., Marine, M. L., Fox, S. E., French, R. A., & Blouin, M. S.
- Venue
- Nature Communications
- Published
- 2016-02-17
- Volume
- 7
- Issue
- 1
- Pages
- 10676-10676
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2280053545
- Cited by
- 269
- References
- 5
- FWCI
- 22.50
- Type
- journal article
- Language
- en
- Open access
- gold
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