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Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone
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Surface localization of TLR6 was dependent on gp96.
“Surface localization of TLR6 was dependent on gp96 (Table 2), as reported.3,4,30”
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Fitzgerald, K. A., & Kagan, J. C. (2020) · Cell · doi:10.1016/j.cell.2020.02.041 · Cited by 2,168
Schopf, F. H., Biebl, M. M., & Buchner, J. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.20 · Cited by 1,540
Mechanisms of Candida albicans Trafficking to the Brain
Liu, Y., Mittal, R., Solis, N. V., Prasadarao, N. V., & Filler, S. G. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002305 · Cited by 93
Weekes, M. P., Antrobus, R., Talbot, S., Hör, S., Simecek, N., Smith, D. L., Bloor, S., Randow, F., & Lehner, P. J. (2012) · Journal of Proteome Research · doi:10.1021/pr201135e · Cited by 82
Pan- and isoform-specific inhibition of Hsp90: Design strategy and recent advances
Yu, J., Zhang, C., & Song, C. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114516 · Cited by 51
Structural transitions modulate the chaperone activities of Grp94
Amankwah, Y. S., Fleifil, Y., Unruh, E., Collins, P., Wang, Y., Vitou, K., Bates, A., Obaseki, I., Sugoor, M., Alao, J. P., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2309326121 · Cited by 22
“Importantly, ATP binding but not hydrolysis also modulates Grp94 interactions with co - chaperones in vivo and is sufficient for folding some client proteins (19, 20).”
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Metadata
- Authors
- Liu, B., Yang, Y., Qiu, Z., Staron, M., Hong, F., Li, Y., Wu, S., Li, Y., Hao, B., Bona, R., Han, D., & Li, Z.
- Venue
- Nature Communications
- Published
- 2010-09-21
- Volume
- 1
- Issue
- 1
- ISSN
- 2041-1723
- Cited by
- 186
- References
- 3
- Language
- en
- Update notices
- erratum (2012-01-31)
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