Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
Kobayashi, Eri H., Suzuki, Takafumi, Funayama, Ryo, Nagashima, Takeshi, Hayashi, Makiko, Sekine, Hiroki, Tanaka, Nobuyuki, Moriguchi, Takashi +3 more·2016·Nature Communications
Cited by (1,002)
Items 701–800 of 1,002
- Aucubin alleviates doxorubicin-induced cardiotoxicity through crosstalk between NRF2 and HIPK2 mediating autophagy and apoptosisWeili Li, Jing Cao, Yawen Zhang, Guanjing Ling, Nannan Tan, Wei Yan, Yuqin Zhang, Xiaoping Wang, Weina Qian, Jinchi Jiang et al. · 2024 · Phytomedicine
- Nrf2-Independent Anti-Inflammatory Effects of Dimethyl Fumarate: Challenges and Prospects in Developing Electrophilic Nrf2 Activators for Neurodegenerative DiseasesYasuhiko Izumi, Yutaka Kōyama · 2024 · Antioxidants
- Mitochondria and the Repurposing of Diabetes Drugs for Off-Label Health BenefitsJoyce Yip, Grace Shu Hui Chiang, Ian Chong Jin Lee, Rachel Lehming-Teo, Kexin Dai, Lokeysh Dongol, Laureen Yi-Ting Wang, Denise Wun Xi Teo, Geok Teng Seah, Norbert Lehming · 2025 · International Journal of Molecular Sciences
- Anti-neuroinflammatory effect of curcumin on Pam3CSK4-stimulated microglial cellsMeiling Jin, Sun Young Park, Qian Shen, Yihong Lai, Xingmei Ou, Zhuo Mao, Dongxu Lin, Yangyang Yu, Weizhen Zhang · 2017 · International Journal of Molecular Medicine
- Sulforaphane Attenuated the Pro-Inflammatory State Induced by Hydrogen Peroxide in SH-SY5Y Cells Through the Nrf2/HO-1 Signaling PathwayMarcos Roberto de Oliveira, Flávia Bittencourt Brasil, Cristina Ribas Fürstenau · 2018 · Neurotoxicity Research
- Regulation of stress signaling pathways by nitro-fatty acidsAshik Jawahar Deen, Virve Sihvola, Jouni Härkönen, Tommi Patinen, Simone Adinolfi, Anna–Liisa Levonen · 2018 · Nitric Oxide
- Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell MiceOluwabukola T. Gbotosho, Maria G. Kapetanaki, Samit Ghosh, Flordeliza S. Villanueva, Solomon Fiifi Ofori-Acquah, Gregory James Kato · 2020 · Frontiers in Immunology
- Nrf2‑Keap1‑ARE‑NQO1 signaling attenuates hyperoxia‑induced lung cell injury by inhibiting apoptosisBowen Weng, Xiaoyue Zhang, Xiaoyun Chu, Xiaohui Gong, Cheng Cai · 2021 · Molecular Medicine Reports
- Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in miceFrederick Adams Ekuban, Cai Zong, Madoka Takikawa, Kota Morikawa, Toshihiro Sakurai, Sahoko Ichihara, Ken Itoh, Masayuki P. Yamamoto, Seiichiroh Ohsako, Gaku Ichihara · 2021 · Toxicology
- Pentagalloylglucose reduces AGE-induced inflammation by activating Nrf2/HO-1 and inhibiting the JAK2/STAT3 pathway in mesangial cellsJinzhi Tong, Jian Fang, Tiantian Zhu, Pan Xiang, Jiaojiao Shang, Lei Chen, Jindong Zhao, Yanxin Wang, Tong Li, Min Sun · 2021 · Journal of Pharmacological Sciences
- Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant SystemGovinda Bhattarai, Han-Sol So, Thi Thu Trang Kieu, Sung‐Ho Kook, Jeong‐Chae Lee, Young‐Mi Jeon · 2021 · Nutrients
- TRIM32 Inhibition Attenuates Apoptosis, Oxidative Stress, and Inflammatory Injury in Podocytes Induced by High Glucose by Modulating the Akt/GSK-3β/Nrf2 PathwayZhao Chen, Lifang Tian, Li Wang, Xiaotao Ma, Fuqian Lei, Xianghui Chen, Rongguo Fu · 2021 · Inflammation
- Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterationsPranshul Sethi, Sidharth Mehan, Zuber Khan, Swesha Chhabra · 2023 · NeuroToxicology
- The melatonin receptor agonist agomelatine protects against acute pancreatitis induced by cadmium by attenuating inflammation and oxidative stress and modulating Nrf2/HO-1 pathwayReem Saleh Alruhaimi, Emad H. M. Hassanein, Mostafa K. Abd El‐Aziz, Maisa Siddiq Abduh, Albandari Bin‐Ammar, Emadeldin M. Kamel, Ayman Moawad Mahmoud · 2023 · International Immunopharmacology
- Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarizationKatalin Kis‐Tóth, Gaurav Manohar Rajani, Allison Simpson, Kate L. Henry, Jennifer Dumont, Robert Peters, Joe Salas, Christine Loh · 2018 · Blood Advances
- Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activationChontida Yarana, Hannah Thompson, Luksana Chaiswing, David Allan Butterfield, Heidi L. Weiss, Subbarao Bondada, Sara Samir Alhakeem, Suriyan Sukati, Daret K. St. Clair · 2019 · Redox Biology
- On-Demand Local Immunomodulation via Epigenetic Control of Macrophages Using an Inflammation-Responsive Hydrogel for Accelerated Wound HealingHye‐Rim Kim, Yunji Joo, Yun-Min Kook, Na Ly Tran, Sang‐Heon Kim, Kangwon Lee, Seung Ja Oh · 2022 · ACS Applied Materials & Interfaces
- Regulation of Cell Proliferation and Nrf2-Mediated Antioxidant Defense: Conservation of Keap1 Cysteines and Nrf2 Binding Site in the Context of the Evolution of KLHL FamilyGregory A. Shilovsky, Daria V. Dibrova · 2023 · Life
- Transcription factor Nrf2 activation regulates NETosis, endothelial injury, and kidney disease in myeloperoxidase-positive antineutrophil cytoplasmic antibody-associated vasculitisY Ueda, Daigo Nakazawa, Saori Nishio, Satoka Shiratori‐Aso, Takashi Kudo, Atsuko Miyoshi, Kanako Watanabe‐Kusunoki, Fumihiko Hattanda, Sari Iwasaki, Takahiro Tsuji et al. · 2024 · Kidney International
- Dual role of Nrf2 signaling in hepatocellular carcinoma: promoting development, immune evasion, and therapeutic challengesLing Gan, Wei Wang, Jinxiu Jiang, Ke Tian, Wei Liu, Zhumin Cao · 2024 · Frontiers in Immunology
- Naturally-derived modulators of the Nrf2 pathway and their roles in the intervention of diseasesTian Wang, Mingjie Liu, Xinyu Li, Sen Zhang, Haoran Gu, Xuan Wei, Xiaoning Wang, Zhen‐Peng Xu, Tao Shen · 2024 · Free Radical Biology and Medicine
- Mangiferin Represses Inflammation in Macrophages Under a Hyperglycemic Environment Through Nrf2 SignalingRavichandran Jayasuriya, Kumar Ganesan, Kunka Mohanram Ramkumar · 2024 · International Journal of Molecular Sciences
- Reprogramming immunity with itaconate: metabolic mechanisms and therapeutic perspectivesHanlin Gao, Minting Ding, Yunchen Liu, Yiying Wang, Susu Zhao, Junyao Chen, Zhi Chen, Gang Wang · 2025 · Inflammation Research
- Effects of deficiency of Kelch‐like ECH‐associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesisEiko Sakai, Masanobu Morita, Masahiro Ohuchi, Mizuho A. Kido, Yutaka Fukuma, Kazuhisa Nishishita, Kuniaki Okamoto, Ken Itoh, Masayuki P. Yamamoto, Takayuki Tsukuba · 2017 · The FASEB Journal
- Nrf2 downregulates zymosan-induced neutrophil activation and modulates migrationDoumet Georges Helou, Sarah Braham, Luc de Chaisemartin, Vanessa Granger, Marie-Hélène Damien, Marc J. Pallardy, Saadia Kerdine‐Römer, Sylvie Chollet‐Martin · 2019 · PLoS ONE
- Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2Anusha Chaparala, Hossam Tashkandi, Alexander A. Chumanevich, Erin E. Witalison, Anthony J. Windust, Taixing Cui, Mitzi Nagarkatti, Prakash S. Nagarkatti, Lorne J. Hofseth · 2020 · Nutrients
- Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor β Signaling PathwayDongfang Xiang, Min Zhao, Xiaofan Cai, Yongxia Wang, Lei Zhang, Helen Yao, Min Liu, Huan Yang, Mingtao Xu, Huilin Li et al. · 2020 · Frontiers in Endocrinology
- Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar MacrophagesStephanie Brook Wall, Rui Li, Brittany Butler, Ashley R. Burg, Hubert Ming Tse, Jennifer L. Larson‐Casey, A. Brent Carter, Clyde J. Wright, Lynette Kay Rogers, Trent E. Tipple · 2021 · Antioxidants
- Vitamin C for sepsis intervention: from redox biochemistry to clinical medicineY. Robert Li, Hong Zhu · 2021 · Molecular and Cellular Biochemistry
- Targeting Macrophage Dysregulation for Viral Infections: Novel Targets for ImmunomodulatorsMonica D. Reece, Ruby Rose Taylor, Colin Song, Christina Gavegnano · 2021 · Frontiers in Immunology
- NRF2 in dermo‐cosmetic: From scientific knowledge to skin care productsMarie‐Céline Frantz, Roger Rozot, Laurent Marrot · 2022 · BioFactors
- NRF2 , a crucial modulator of skin cells protection against vitiligo, psoriasis, and cancerEmiliano Panieri, Pelin Telkoparan‐Akillilar, Luciano Saso · 2022 · BioFactors
- Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell deathPanpan Zhao, Yan Wang, Qiankun Yang, Guili Yu, Fenfen Ma, Jingquan Dong · 2022 · Environmental Science and Pollution Research
- Age-Related Decline in Nrf2/ARE Signaling Is Associated with the Mitochondrial DNA Damage and Cognitive ImpairmentsArtem P. Gureev, Victoria G. Khorolskaya, Irina S. Sadovnikova, Ekaterina A. Shaforostova, Vadim R. Cherednichenko, Inna Yu. Burakova, Egor Y. Plotnikov, Vasily N. Popov · 2022 · International Journal of Molecular Sciences
- Does Nrf2 Play a Role of a Master Regulator of Mammalian Aging?Roman A. Zinovkin, Natalia D. Kondratenko, Liudmila A. Zinovkina · 2022 · Biochemistry (Moscow)
- Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Sleep Quality in Patients Undergoing Laparoscopic Gastrointestinal Tumor Surgery: A Prospective, Randomized Controlled TrialJun Wang, Fei-Fei Lu, Miao-Miao Ge, Li-Wen Wang, Gang Wang, Guanwen Gong, Xin-Xin Liu, Wen-Zhuo Zhang, Fei‐Long Ning, Bao-He Chen et al. · 2023 · Pain and Therapy
- Aging, NRF2, and TAU: A Perfect Match for Neurodegeneration?Mirjam Brackhan, Marina Arribas-Blázquez, Isabel Lastres‐Becker · 2023 · Antioxidants
- Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitisKentaro Akiyama, Eiji Warabi, Kosuke Okada, Toru Yanagawa, Tetsuro Ishii, Katsumi Kose, Katsutoshi Tokushige, Kazunori Ishige, Yuji Mizokami, Kenji Yamagata et al. · 2017 · EXPERIMENTAL ANIMALS
- Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseasesCuadrado, Antonio, Cazalla, Eduardo, Bach, Anders, Bathish, Boushra, Naidu, Sharadha Dayalan, DeNicola, Gina M., Dinkova-Kostova, Albena T., Fernández-Ginés, Raquel, Grochot-Przeczek, Anna, Hayes, John D. et al. · 2025 · Redox Biology
- Bivalent inhibitors of the BTB E3 ligase KEAP1 enable instant NRF2 activation to suppress acute inflammatory responseMengchen Lu, Jianai Ji, Yifei Lv, Jing Zhao, Yuting Liu, Qiong Jiao, Tian Liu, Yi Mou, Qidong You, Zhengyu Jiang · 2023 · Cell chemical biology
- Cell polarization in ischemic stroke: molecular mechanisms and advancesYuanwei Li, Xiaoxiao Xu, Xuan Wu, Jiarui Li, Shiling Chen, Danyang Chen, Gaigai Li, Zhouping Tang · 2024 · Neural Regeneration Research
- The mechanisms underlying Chinese medicines to treat inflammation in diabetic kidney diseaseLingchen Deng, Chunru Shi, Run Li, Yifan Zhang, Xiaochen Wang, Guangyan Cai, Quan Hong, Xiangmei Chen · 2024 · Journal of Ethnopharmacology
- Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathwaysJuntao Guo, Hanyu Li, Chao Cheng, Jia-Xue Shi, Hai-Nan Ruan, Jun Li, Chan‐Min Liu · 2024 · Food and Chemical Toxicology
- Oxidative–Inflammatory Crosstalk and Multi-Target Natural Agents: Decoding Diabetic Vascular ComplicationsJingwen Liu, Kexin Li, Zixin Yi, Saqirile, Changshan Wang, Rui Yang · 2025 · Current Issues in Molecular Biology
- NRF2 Is One of the Players Involved in Bone Marrow Mediated Drug Resistance in Multiple MyelomaChia‐Hung Yen, Hui‐Hua Hsiao · 2018 · International Journal of Molecular Sciences
- Interaction of Genetic Variations in NFE2L2 and SELENOS Modulates the Risk of Hashimoto's ThyroiditisLiliana Ribeiro Santos, Cecília Durães, Panos G. Ziros, Ana Pestana, César Esteves, Celestino Neves, Davide Maurício Carvalho, Massimo Bongiovanni, Cédric O. Renaud, Dionysios V. Chartoumpekis et al. · 2019 · Thyroid
- Sulforaphane ameliorates serum starvation‐induced muscle atrophy via activation of the Nrf2 pathway in cultured C2C12 cellsJae Yun Moon, Da Jeong Kim, Hye Sun Kim · 2020 · Cell Biology International
- Cardamonin Inhibits Oxazolone-Induced Atopic Dermatitis by the Induction of NRF2 and the Inhibition of Th2 Cytokine ProductionOk-Kyung Yoo, Won Jun Choi, Young‐Sam Keum · 2020 · Antioxidants
- Inhibition of TLR2/TLR4 alleviates the Neisseria gonorrhoeae infection damage in human endometrial epithelial cells via Nrf2 and NF-KβsignalingYun Yang, Shasha Liu, Jixiao Liu, Na Ta · 2020 · Journal of Reproductive Immunology
- Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?Sawsan Elgohary, Aya A. Elkhodiry, Nada Sherif Amin, Ulrike Stein, Hend Mohamed El Tayebi · 2021 · Cells
- Mechanisms of Kidney Cell Pyroptosis in Chronic Kidney Disease and the Effects of Traditional Chinese MedicineBaozhu Ding, Guoping Ma, Zinuo Wang, Wenjie Liang, Weifang Gao · 2021 · Evidence-based Complementary and Alternative Medicine
- Lability of the Nrf2/Keap/ARE Cell Defense System in Different Models of Cell Aging and Age-Related PathologiesGregory A. Shilovsky · 2022 · Biochemistry (Moscow)
- Regulation of the immune response to contact sensitizers by Nrf2Romain Vallion, Saadia Kerdine‐Römer · 2022 · Contact Dermatitis
- Red Palm Oil Ameliorates Oxidative Challenge and Inflammatory Responses Associated with Lipopolysaccharide-Induced Hepatic Injury by Modulating NF-κβ and Nrf2/GCL/HO-1 Signaling Pathways in RatsOlawale Razaq Ajuwon, Jeanine Lucasta Marnewick, Oluwafemi Omoniyi Oguntibeju, Lester M. Davids · 2022 · Antioxidants
- Oxidative Stress and Inflammatory Biomarkers for Populations with Occupational Exposure to Nanomaterials: A Systematic Review and Meta-AnalysisXiaogang Luo, Dongli Xie, Jianchen Hu, Jing Su, Zhebin Xue · 2022 · Antioxidants
- γ-Mangostin abrogates AINT-induced cholestatic liver injury: Impact on Nrf2/NF-κB/NLRP3/Caspase-1/IL-1β/GSDMD signallingMaan Talaat Abdullah Khayat, Khadijah Ahmad Mohammad, Gamal Abdallah Mohamed, Dina S. El‐Agamy, Wael M. Elsaed, Sabrin R. M. Ibrahim · 2023 · Life Sciences
- Amentoflavone Exerts Anti-Neuroinflammatory Effects by Inhibiting TLR4/MyD88/NF-κB and Activating Nrf2/HO-1 Pathway in Lipopolysaccharide-Induced BV2 MicrogliaShikuo Rong, Chunrong Yang, Feng Wang, Yiyang Wu, Kuisheng Sun, Tao Sun, Ze-Yu Wu · 2022 · Mediators of Inflammation
- Targeting ferroptosis promotes diabetic wound healing via Nrf2 activationTongcai Wang, Zheng Yin, Jun Zhang, Zhongming Wu · 2024 · Heliyon
- Hypoxia sensing in resident cardiac macrophages regulates monocyte fate specification following ischemic heart injuryFarid F. Kadyrov, Andrew L. Koenig, Junedh Amrute, Hao Dun, Wenjun Li, Carla J. Weinheimer, Jessica M. Nigro, Attila Kovács, Andrea L. Bredemeyer, Steven Hoseong Yang et al. · 2024 · Nature Cardiovascular Research
- An Activity-Based Sensing Approach to Multiplex Mapping of Labile Copper Pools by Stimulated Raman ScatteringYishu Jiang, Elsy D. El Khoury, Aidan T. Pezacki, Naixin Qian, Miku Oi, Laura Torrente, Sophia G. Miller, Martina Ralle, Gina M. DeNicola, Wei Min et al. · 2024 · Journal of the American Chemical Society
- Mechanisms of Keap1/Nrf2 modulation in bacterial infections: implications in persistence and clearanceMarco Antonio Romero-Durán, Octavio Silva-García, Jose Manuel Perez‐Aguilar, Victor Manuel Baizabal-Aguirre · 2024 · Frontiers in Immunology
- Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related DiseasesYi Zhou, Lin Zhu, Yunyun Yuan, Shuang Ling, Jin‐Wen Xu · 2020 · Oxidative Medicine and Cellular Longevity
- Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic CompoundsFrancesca Fagiani, Michele Catanzaro, Erica Buoso, Filippo Basagni, Daniele Di Marino, Stefano Raniolo, Marialaura Amadio, Eric H. Frost, Emanuela Corsini, Marco Racchi et al. · 2020 · Frontiers in Pharmacology
- Study on the Correlation Between NF-κB and Central FatigueXingzhe Yang, Feng Li, Yan Liu, Danxi Li, Jie Li · 2021 · Journal of Molecular Neuroscience
- Pterostilbene accelerates wound healing by modulating diabetes-induced estrogen receptor β suppression in hematopoietic stem cellsWeiguo Xie, Xueqing Zhou, Weigang Hu, Zhigang Chu, Qiongfang Ruan, Haimou Zhang, Min Li, Hongyu Zhang, Xiaodong Huang, Paul Yao · 2020 · Burns & Trauma
- Coffee ingredients, hydroquinone, pyrocatechol, and 4-ethylcatechol exhibit anti-inflammatory activity through inhibiting NF-κB and activating Nrf2Megumi Funakoshi‐Tago, Mari Matsutaka, Shingo Hokimoto, Kenji Kobata, Kenji Tago, Hiroomi Tamura · 2022 · Journal of Functional Foods
- Peptides, Exopolysaccharides, and Short-Chain Fatty Acids from Fermented Milk and Perspectives on Inflammatory Bowel DiseasesR. Sigala-Robles, Lourdes Santiago‐López, Adrián Hernández‐Mendoza, Belinda Vallejo‐Córdoba, Verónica Mata‐Haro, Abraham Wall‐Medrano, Aaron Fernando González-Córdova · 2022 · Digestive Diseases and Sciences
- TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage–Related Neutrophilic Inflammation in AsthmaBingqing Shi, Yuqiu Hao, Wei Li, Hongna Dong, Mengting Xu, Peng Gao · 2022 · Frontiers in Immunology
- Nrf2 for a key member of redox regulation: A novel insight against myocardial ischemia and reperfusion injuriesXuejie Han, Hongxia Wang, Fenghe Du, Xiangjun Zeng, Caixia Guo · 2023 · Biomedicine & Pharmacotherapy
- RETRACTED: Nrf2 pathway activation with natural plant-derived exosome-like nanovesicle/hydrogel preparations for oxidative stress modulation in inflammation related diseasesQi Pan, Zhengyang Bao, Yixuan Wang, Tao Yu Wan · 2023 · Chemical Engineering Journal · Retracted
- Commiphora molmol Modulates Glutamate‐Nitric Oxide‐cGMP and Nrf2/ARE/HO‐1 Pathways and Attenuates Oxidative Stress and Hematological Alterations in Hyperammonemic RatsAyman Moawad Mahmoud, Sultan Alqahtani, Sarah I. Othman, Mousa O. Germoush, Omnia E. Hussein, Gadh Al-Basher, Jong Seong Khim, Maha Abdulla Alqaraawi, Hanan M. Alharbi, Abdulmannan Fadel et al. · 2017 · Oxidative Medicine and Cellular Longevity
- A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAEHsi-Ju Wei, Tej Kumar Pareek, Qi Liu, John J. Letterio · 2017 · Scientific Reports
- Hemistepsin A ameliorates acute inflammation in macrophages via inhibition of nuclear factor-κB and activation of nuclear factor erythroid 2-related factor 2Jae Kwang Kim, Ji‐Eun Lee, Eun Hye Jung, Ji Yun Jung, Dae Hwa Jung, Sae‐Kwang Ku, Il Je Cho, Sang Chan Kim · 2017 · Food and Chemical Toxicology
- Keleku-Lukwete N, Suzuki M, Panda H, et al. Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice. Blood Adv. 2019;3(8):1285-1297.Nadine Keleku-Lukwete, Mikiko Suzuki, Harit Panda, Akihito Otsuki, Fumiki Katsuoka, Ritsumi Saito, Daisuke Saigusa, Akira Uruno, Masayuki P. Yamamoto · 2019 · Blood Advances
- A novel target TAX1BP1 and P38/Nrf2 pathway independently involved in the anti-neuroinflammatory effect of isobavachalconeZhipeng Li, Qiaoyun Wang, Haiyun Luan, Ming Yang, Yanni Li, Geng Tian, Wenbin He · 2020 · Free Radical Biology and Medicine
- Maternal Diabetes Induces Immune Dysfunction in Autistic Offspring Through Oxidative Stress in Hematopoietic Stem CellsJianping Lu, Meifang Xiao, Xiaoling Guo, Yujie Liang, Min Wang, Jianchang Xu, Liyan Liu, Zichen Wang, Gang Zeng, Kelly Liu et al. · 2020 · Frontiers in Psychiatry
- The Role of PARP1 in Monocyte and Macrophage Commitment and Specification: Future Perspectives and Limitations for the Treatment of Monocyte and Macrophage Relevant Diseases with PARP InhibitorsMaciej Sobczak, Marharyta Zyma, Agnieszka Robaszkiewicz · 2020 · Cells
- Role of Inflammation in Progression of Chronic Kidney Disease in Type 2 Diabetes Mellitus: Clinical ImplicationsYasuhiro Oda, Hiroshi Nishi, Masaomi Nangaku · 2023 · Seminars in Nephrology
- Sulforaphane decreases oxidative stress and inhibits NLRP3 inflammasome activation in a mouse model of ulcerative colitisZijuan Zhou, Jianyi Dong, Yang Qiu, Guolin Zhang, Kun Wei, Liheng He, Yining Sun, Haozheng Jiang, Shuangshuang Zhang, Xinrui Guo et al. · 2024 · Biomedicine & Pharmacotherapy
- Phytochemical compounds targeting on Nrf2 for chemoprevention in colorectal cancerYuandong Zhu, Qinghua Yang, Haiyuan Liu, Zhengming Song, Wenbin Chen · 2020 · European Journal of Pharmacology
- Interleukin‐5 deletion promotes sepsis‐induced M1 macrophage differentiation, deteriorates cardiac dysfunction, and exacerbates cardiac injury via the NF‐κB p65 pathway in miceWanqian Liang, Jianhua Li, Caiyan Bai, Yingen Chen, Yan Li, Guotao Huang, Xuehui Wang · 2020 · BioFactors
- Docosahexaenoic Acid Induces Expression of NAD(P)H: Quinone Oxidoreductase and Heme Oxygenase-1 through Activation of Nrf2 in Cerulein-Stimulated Pancreatic Acinar CellsYu Jin Ahn, Joo Weon Lim, Hyeyoung Kim · 2020 · Antioxidants
- Ganoderma lucidum ameliorates the diabetic nephropathy via down-regulatory effect on TGFβ-1 and TLR-4/NFκB signalling pathwaysHanan M. Hassan, Yasmen F. Mahran, Amal M. H. Ghanim · 2021 · Journal of Pharmacy and Pharmacology
- A Crosstalk between the Biorhythms and Gatekeepers of Longevity: Dual Role of Glycogen Synthase Kinase-3Gregory A. Shilovsky, T. S. Putyatina, Моргунова Галина Васильевна, А. В. Селиверстов, Vasily V. Ashapkin, Е. В. Сорокина, Alexander V Markov, Vladimir P. Skulachev · 2021 · Biochemistry (Moscow)
- Buyang Huanwu Decoction Enhances Revascularization via Akt/GSK3β/NRF2 Pathway in Diabetic Hindlimb IschemiaXiaoyi Bao, Li-Hui Deng, Zijun Huang, Abdirizak s Daror, Zi-Hao Wang, Wang-Jun Jin, Zhuang Zhuang, Qiang Tong, Guo‐qing Zheng, Yan Wang · 2021 · Oxidative Medicine and Cellular Longevity
- The Importance of Nutraceuticals in COVID-19: What’s the Role of Resveratrol?Elisa Domi, Malvina Hoxha, Entela Kolovani, Domenico Tricarico, Bruno Zappacosta · 2022 · Molecules
- Dimethyl itaconic acid improves viability and steroidogenesis and suppresses cytokine production in LPS-treated bovine ovarian granulosa cells by regulating TLR4/nfkβ, NLRP3, JNK signaling pathwaysMohammad Reza Tabandeh, Sadegh Jozaie, Zohreh Ghotbeddin, Saad Gorani · 2022 · Research in Veterinary Science
- Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 PathwayJin-Fang Luo, Hua Zhou, Chon-Kit Lio · 2022 · Molecules
- Involvement of redox signalling in tumour cell dormancy and metastasisBeatriz Puente-Cobacho, Alfonso Varela‐López, José Luis Quiles, Laura Vera Ramírez · 2023 · Cancer and Metastasis Reviews
- Antioxidant and Anti-Inflammatory Activities of High-Glucosinolate-Synthesis Lines of Brassica rapaHyun Jin Choi, Hail Kim, Sanghee Han, Hyun Woo Park, In Jin Ha, Jung Sun Kim, Seok‐Geun Lee · 2023 · Antioxidants
- The Standardized Extract of Centella asiatica and Its Fractions Exert Antioxidative and Anti-Neuroinflammatory Effects on Microglial Cells and Regulate the Nrf2/HO-1 Signaling PathwayAqilah Hambali, Nor Atiqah Jusril, Nur Fariesha Md Hashim, Nizar Abd Manan, Siti Khadijah Adam, Muhammad Zulfadli Mehat, Mohd Ilham Adenan, Johnson Stanslas, Hafizah Abdul Hamid · 2024 · Journal of Alzheimer s Disease
- Anemoside B4 alleviates arthritis pain via suppressing ferroptosis‐mediated inflammationChenlu Guo, Yuan-Fen Yue, Bojun Wang, Shaohui Chen, Dai Li, Fangshou Zhen, Ling Liu, Haili Zhu, Min Xie · 2024 · Journal of Cellular and Molecular Medicine
- A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implantYulu Yang, Xianhui Zhang, Yao Yang, Pengfei Gao, Wuzhe Fan, Tao Zheng, Weihu Yang, Yu Jie Tang, Kaiyong Cai · 2024 · Bioactive Materials
- Preconditioning by Low Dose LPS Prevents Subsequent LPS-Induced Severe Liver Injury via Nrf2 Activation in Mice.Masato Nakasone, Kazuhiro Nakaso, Yosuke Horikoshi, Takehiko Hanaki, Yoshinori Kitagawa, Toru Takahashi, Yoshimi Inagaki, Tatsuya Matsura · 2016 · PubMed Central
- Brassinin, a phytoalexin in cruciferous vegetables, suppresses obesity‐induced inflammatory responses through the Nrf2‐HO‐1 signaling pathway in an adipocyte‐macrophage co‐culture systemBobin Kang, Chae Young Kim, Jisu Hwang, Hyung Joo Suh, Hyeon‐Son Choi · 2019 · Phytotherapy Research
- Dengue virus infection and Nrf2 regulation of oxidative stressAlessandra Zevini, Matteo Ferrari, David P. Olagnier, John B. Hiscott · 2020 · Current Opinion in Virology
- Nuclear protein HMGN2 attenuates pyocyanin-induced oxidative stress via Nrf2 signaling and inhibits Pseudomonas aeruginosa internalization in A549 cellsLiu, Keyun, Wang, Xinyuan, Sha, Kaihui, Zhang, Fumei, Xiong, Feng, Wang, Xiaoying, Chen, Junli, Li, Jingyu, Churilov, Leonid P., Chen, Shanze et al. · 2017 · Free Radical Biology and Medicine
- 17β-Estradiol strongly inhibits azoxymethane/dextran sulfate sodium-induced colorectal cancer development in Nrf2 knockout male miceChin‐Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Joo Hee Son, Jeong Eun Yu, Eun Hee Shin, Hana Lee, Do-Hee Kim, Young‐Joon Surh · 2020 · Biochemical Pharmacology
- Protective Effect of Yi Shen Pai Du Formula against Diabetic Kidney Injury via Inhibition of Oxidative Stress, Inflammation, and Epithelial‐to‐Mesenchymal Transition in db/db MiceQilin Zhang, Xiaocui Liu, Mitchell Anthony Sullivan, Chen Shi, Bin Deng · 2021 · Oxidative Medicine and Cellular Longevity
- Peroxisomes Are Critical for the Development and Maintenance of B1 and Marginal Zone B Cells but Dispensable for Follicular B Cells and T CellsJonathan Muri, Basak Corak, Mai Matsushita, Myriam I Baes, Manfred Köpf · 2022 · The Journal of Immunology