Senescent tumor cells lead the collective invasion in thyroid cancer

Kim, Young Hwa, Choi, Yong Won, Lee, Jeonghun, Soh, Euy Young, Kim, Jang-Hee, Park, Tae Jun·2017·Nature Communications
DOI 10.1038/ncomms15208

Cited by (253)

Items 201–253 of 253

  1. Metabolic fingerprinting by nuclear magnetic resonance of hepatocellular carcinoma cells during p53 reactivation‐induced senescence
    Philipp Knopf, Jesús Pacheco‐Torres, Laimdota Zizmare, Noriko Mori, Flonné B. Wildes, Benyuan Zhou, Balaji Krishnamachary, Yelena Mironchik, Manfred Kneilling, Christoph Trautwein et al. · 2024 · NMR in Biomedicine
  2. Mechanism of Tumor Growth and Metastasis
    Fernanda Carolina Ribeiro Dias, Jaciel B. Oliveira, Bruna Santana Silva Pinheiro, Helen Fernanda Marcelino Pacheco, Julia Gonçalves Rodrigues, Jhessyka L. F. Fernandes, Marcos de Lucca Moreira Gomes · 2024 · Interdisciplinary cancer research
  3. Development and Validation of Potential Molecular Subtypes and Signatures of Thyroid Carcinoma Based on Aging-related Gene Analysis
    Zhi Li, Jia Li, Lu Zhang, Lu Zhang, Huang-Ren Zhou, Yuke Bai, Juan Lv, Zhi-Yong Deng, Chao Liu · 2023 · Cancer Genomics & Proteomics
  4. Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma
    Yinde Huang, Han Jiang, Guangwen Xu, Xin Li, Wenbin Chen, Yu Lun, Jian Zhang · 2024 · Aging
  5. The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
    Apsra Nasir, Sharon Camacho, Alec T. McIntosh, Garrett T. Graham, Raneen Rahhal, Molly E. Huysman, Fahda Alsharief, Anna Tate Riegel, Gray W. Pearson · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  6. Comprehensive analysis of malignant subtypes of lung adenocarcinoma based on multi-omics landscape and functional validation of prognostic biomarker BAIAP2L2
    Bowei Jiang, Yuan Gan, Wanshuo Wei, Meichun Yang, Jiahui Long, Xiujuan He, Hanbo Yu, Jianjun Wen, Zhongheng Wei, Qijun Long · 2025 · Scientific Reports
  7. Deciphering functional intra-tumoral heterogeneity in BRAFV600E-driven mouse thyroid cancer reveals EMT trajectory and metabolic remodeling
    Jing Yu, Siyi Shen, Rongkui Luo, Tianyuan Qiu, Jingjing Chen, Wenqing Kong, Ruisen Ma, Ying Yan, Zhoumin Niu, Mei Ma et al. · 2026 · Oncogene
  8. Tumor-derived circulating DNA can induce senescence and SASP activation in mouse embryonic fibroblasts
    Ekin Çelik, Ertan Kanbur · 2026 · Biogerontology
  9. Senescence-associated and immune-related 9p21.3 locus genes in colorectal cancer: epigenetic architecture, molecular landscape and therapeutic possibilities
    Darya A. Lisitsa, Vadim V. Shindyapin, Artem R. Nurislamov, Oleg N. Demidov, Daria A. Bogdanova · 2026 · Frontiers in Cell and Developmental Biology
  10. Upregulation of CSN8 induces a unique senescence-like state with robust tumor-promoting properties in epithelial ovarian cancer cells under hypoxia
    Mengyuan Ruan, Xiaoxue Xi, Ning Guo, Feng Wang, Ronglin Ma, Songguang Ju, Jinghuan Lv, Shunyu Hou, Songwen Ju · 2026 · Journal of Translational Medicine
  11. Extracellular vesicles from chemotherapy-induced senescent tumor cells reprogram hepatic phospholipid metabolism to promote pancreatic cancer liver metastasis
    Baian Tao, Yecheng Xu, Wenteng Miao, Zhenmei Chen, Jichun Gu, Yi Guo, Le Chen, Yang Di, He He, J J Chen et al. · 2026 · Journal of Experimental & Clinical Cancer Research
  12. CCL5 and GLUT1 define leader cells in collective invasion of colorectal cancer
    Feifei Wang, Zhaowen Zhang, Zhicheng Zeng, Xiaohui Zhu, Liyao Mai, Yin Yao, Ceng Zhang, Wei Kang, Xiangkun Wu, Honghui Jiang et al. · 2026 · The Journal of Pathology
  13. The multifaceted roles of cellular senescence in liver pathophysiology: from tissue repair to tumor progression
    Efi Tsouri, Niovi Athanasopoulou, Leila Akkari, Serena Vegna · 2026 · Seminars in Immunology
  14. Senescence and the Microenvironment
    Mohit Kumar Rai, Pallavi Yadav, Arjun S. Katailiha, Aloukick Kumar Singh, Sandeep Kumar Yadav · 2025 · Springer eBooks
  15. Predicting implicit concept embeddings for singular relationship discovery replication of closed literature-based discovery
    Clint Cuffy, Bridget Thomson McInnes · 2025 · Frontiers in Research Metrics and Analytics
  16. A novel platform for precise senolysis
    Anastasia Conti, Raffaella Di Micco · 2025 · Mechanisms of Ageing and Development
  17. Nutrigenomics of Aging
    Nelma M. Palminha, Sara A. Hashish, Eman Rabie, S. Saber · 2022 · Nutritional neurosciences
  18. The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
    Apsra Nasir, Sharon Camacho, Alec T. McIntosh, Garrett T. Graham, Raneen Rahhal, Molly E. Huysman, Fahda Alsharief, Anna Tate Riegel, Gray W. Pearson · 2023
  19. Birth and death of cellular senescence
    Boshi Wang · 2020
  20. Inflammatory cancer associated fibroblasts decisive role in therapy resistance among rectal cancer patients
    Adele M. Nicolas · 2022
  21. Preclinical evaluation of senescence-based strategies to improve cancer therapy
    Alejandra Estepa‐Fernández · 2022
  22. The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
    Apsra Nasir, Sharon Camacho, Alec T. McIntosh, Garrett T. Graham, Raneen Rahhal, Molly E. Huysman, Fahda Alsharief, Anna Tate Riegel, Gray W. Pearson · 2023
  23. Author Response: The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
    Apsra Nasir, Sharon Camacho, Alec T. McIntosh, Garrett T. Graham, Raneen Rahhal, Molly E. Huysman, Fahda Alsharief, Anna Tate Riegel, Gray W. Pearson · 2023
  24. Lenfadenopatiye Multidisipliner Yaklaşım
    Mustafa Cenk Yılmaz, Semih Tan, Emine Tural, Itır Ebru Zemheri, Pınar Engin Zerk, Zerrin Kutlu, Eren Altun, Emine Kizilay, Çağlayan Keklikkıran, Ömer TOPDAĞI et al. · 2022 · Akademisyen Kitabevi eBooks
  25. Additional file 4 of Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease
    Bo Pan, Dongyi Zhao, Yaqian Liu, Na Li, Chen Song, Ning Li, Xuelu Li, Man Li, Zuowei Zhao · 2020 · Figshare
  26. Inflammation-Associated Stem Cells in Gastrointestinal Cancers: Their Utility as Prognostic Biomarkers and Therapeutic Targets
    Beauty Kumari, Aniket Tiwari, Sakshi Meena, Dinesh Kumar Ahirwar · 2024 · Cancers
  27. Tumor-associated senescent macrophages, their markers and their role in the tumor microenvironment (review)
    Tamara V. Pukhalskaia, T. R. Yrakova, Daria A. Bogdanova, Oleg N. Demidov · 2024 · Biochemistry (Moscow)
  28. Senescence cell signature associated with poor prognosis, epithelial–mesenchymal transition, solid histology, and spread through air spaces in lung adenocarcinoma
    Young Wha Koh, Jae-Ho Han, Seokjin Haam, Hyun Woo Lee · 2024 · GeroScience
  29. Senescence Inducers and Senolytics – Pathways and Drugs Targeting Cellular Senescence
    Irfan Khan, Benjamin N Friedland, Patrick Alexander Forcelli, Marcel O. Schmidt, Anton Wellstein · 2025 · Preprints.org
  30. Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification
    Bin Yu, Shuyan Zhao, Yunhua Zhu, Junjie Luo, Ke Zheng, Bin-Jie Shen, Yi-Lin Shen, Huan-Xin Zhong · 2025 · Frontiers in Genetics
  31. The dual role of cellular senescence in tumor occurrence and development
    Xiaoshan Huang, Zi-Rui Wang, Buling Wu, Wen-wei Song · 2025 · Discover Medicine
  32. Age-Associated Alterations in Cytokine and Extracellular Matrix Remodeling in the Papillary Thyroid Cancer Tumor Microenvironment
    Grace R. Thompson, Fahong Yu, Song Han, Gerik W. Tushoski-Alemán, Jordan A. McKean, Steven J. Hughes, Aditya S. Shirali · 2025 · Annals of Surgical Oncology
  33. Additional file 2 of Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease
    Bo Pan, Zhao, Dongyi, Liu, Yaqian, Li, Na, Song, Chen, Li, Ning, Li, Xuelu, Li, Man, Zhao, Zuowei · 2020 · Figshare
  34. Additional file 3 of Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease
    Bo Pan, Zhao, Dongyi, Liu, Yaqian, Li, Na, Song, Chen, Li, Ning, Li, Xuelu, Li, Man, Zhao, Zuowei · 2020 · Figshare
  35. Additional file 1 of Establishment and characterization of breast cancer organoids from a patient with mammary Paget’s disease
    Bo Pan, Zhao, Dongyi, Liu, Yaqian, Li, Na, Song, Chen, Li, Ning, Li, Xuelu, Li, Man, Zhao, Zuowei · 2020 · Figshare
  36. Additional file 1 of The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
    Sabrina J. Ritch, Abu Shadat Mohammod Noman, Alicia Alejandra Goyeneche, Carlos Marcelo Telleria · 2023 · Figshare
  37. Additional file 9 of The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
    Sabrina J. Ritch, Abu Shadat Mohammod Noman, Alicia Alejandra Goyeneche, Carlos Marcelo Telleria · 2023 · Figshare
  38. Prognostic impact of spatial niches in prostate cancer
    Felix Schneider, Sarah Heike Böning, Beatriz Coelho Antunes, Adam Kaczorowski, Magdalena Görtz, Viktoria Schütz, Johannes Huber, Albrecht Stenzinger, Markus Hohenfellner, Stefan M. Duensing et al. · 2026 · Scientific Reports
  39. Characterization of the Signaling Pathways Involved in Cellular Cannibalism Elicited by Ionizing Radiation
    Dorine de Jong · 2018 · theses.fr (ABES)
  40. Découverte d'une sénescence associée à un phénotype sécrétoire déclenchée par les défauts mécaniques de la cellule endothéliale lors de la perte de CCM2 dans un modèle de cavernome cérébral
    Daphné Vannier · 2020 · theses.fr (ABES)
  41. Rôle de l’immunosurveillance des cellules sénescentes dans le cancer et le vieillissement
    Charlène Iltis · 2020 · theses.fr (ABES)
  42. The role of senescent tumor cells in carcinogenesis and antitumor immunity
    Есипова Дарья Дмитриевна, Муругина Нина Евгеньевна, E.V. Slizhevskaya, Boris V. Pinegin, Mikhail V. Pashenkov · 2026 · Immunologiya
  43. An APOC1 + inflammatory CAF-like state drives a senescent, treatment-resistant niche in rheumatoid arthritis
    Risa Yoshihara, Sotaro Nakajima, Reo Yamazato, Tomoya Yoshida, Ikuo Takazawa, Yasunori Omata, Teh-Wei Wang, Kazuyoshi Ishigaki, Takahiro Itamiya, Mineto Ota et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Co-targeting CDK4/6 and MEK reverses mesenchymal transition in therapy-refractory BRAF-altered pediatric high-grade glioma
    Lisa Mayr, Leah Mager, Lisa Gabler, Dominik Kirchhofer, Julia Freund, Kallen Schwark, Benison C. Lau, Sarah Machreich, Daniel Senfter, Mia Neumüller et al. · 2026 · Journal of Experimental & Clinical Cancer Research
  45. eHsp90α enhances breast cancer cell invasion by activating the LRP1-EGFR/AKT-twist/snail signaling axis in cancer-associated fibroblasts
    S W Cho, Se-Hee Yoon, Chang Gyo Park, Hoi Young Lee · 2026 · Archives of Pharmacal Research
  46. Epigenetic analysis reveals aberrant aging in thyroid cancer
    Yihan Hou, Chenwen Luo, Yao Yao, Yongping Luo · 2026 · Endocrine Research
  47. Dorsal horn DCC amplification loop induced by endplate osteoclasts generates chronic nociplastic low back pain in male mice
    Dayu Pan, Mengxi Shen, Elizabeth Abatan, Jinjian Zheng, Philip R. Nasser, Damien M. Laudier, Chao Kong, Lei Yan, Zhaozhu Qiu, James C. Iatridis et al. · 2026 · Nature Communications
  48. Theragenerative Nanomaterials: Integrating Therapy, Regeneration, and Diagnosis—Navigating the Shared Pathways Between Tissue Repair and Malignancy
    Pardis Yousefi Talouki, Reyhaneh Tamimi, Nazanin Jafaripour · 2026 · International Journal of Nanomedicine
  49. Closing the gap in aging science: unlocking the potential of nanoparticles in senescence therapy
    Ertan Kanbur, Ömer Faruk Aydin · 2026 · Biogerontology
  50. Chromosomal instability in cancer: sources, consequences and new therapeutic opportunities
    Angela Flavia Serpico, Domenico Grieco · 2026 · Signal Transduction and Targeted Therapy
  51. Cellular senescence: six decades of discovery and reinvention
    Myrthe Klaver, Lotte S. Steeneken, Naomi Veeningen, Abdullah Altulea, Marco Demaria · 2026 · The EMBO Journal
  52. Targeting senescence-mediated immune resistance for enhanced tumor immunotherapy
    Siyu Chen, Jingyi Su, Aojia Jin, Chencong Liu, Ping Zhang, Zhiai Xu, Jiaxing Pan, Yi Lai, Haijun Yu · 2026 · Journal of Cancer Metastasis and Treatment
  53. Dataset related to article "Spatial resolution of cellular senescence dynamics in human colorectal liver metastasis"
    Ombretta Garbarino, Luca Lambroia, Gianluca Basso, Veronica Marrella, Barbara Franceschini, Cristiana Soldani, Fabio Pasqualini, Desirée Giuliano, Giulio Costa, Clelia Peano et al. · 2023 · Zenodo (CERN European Organization for Nuclear Research)