Extracellular matrix inhibits structural and functional plasticity of dendritic spines in the adult visual cortex

Regeneration beyond the glial scar

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Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP

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Chondroitinase ABC promotes functional recovery after spinal cord injury

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Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

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Long-term dendritic spine stability in the adult cortex

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Transient and persistent dendritic spines in the neocortex in vivo

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Perineuronal Nets Protect Fear Memories from Erasure

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Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle

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Parallels between the extracellular matrix roles in developmental biology and cancer biology

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Cholinergic boutons are closely associated with excitatory cells and four subtypes of inhibitory cells in the inferior colliculus

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Perineuronal nets in subcortical auditory nuclei of four rodent species with differing hearing ranges

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Microglial depletion increases aggrecan and hyaluronan levels in the diffuse and aggregated extracellular matrix of the mouse brain

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Wild‐type MECP2 expression coincides with age‐dependent sensory phenotypes in a female mouse model for Rett syndrome

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Ethanol Exposure Transiently Elevates but Persistently Inhibits Tyrosine Kinase Activity and Impairs the Growth of the Nascent Apical Dendrite

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Osteopontin and Integrin Mediated Modulation of Post-Synapses in HIV Envelope Glycoprotein Exposed Hippocampal Neurons

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In Situ Altering of the Extracellular Matrix to Direct the Programming of Endogenous Stem Cells

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Selective Deletion of Methyl CpG Binding Protein 2 from Parvalbumin Interneurons in the Auditory Cortex Delays the Onset of Maternal Retrieval in Mice

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Motor recovery through perineuronal net modulation in a Parkinson’s disease mouse model

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Perineuronal nets and subtypes of GABAergic cells differentiate auditory and multisensory nuclei in the intercollicular area of the midbrain

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Multidimensional analysis of a social behavior identifies regression and phenotypic heterogeneity in a female mouse model for Rett syndrome

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Inhibitory circuit dysfunction as a potential contributor to cortical reorganization in Glioblastoma progression

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Regulation of CNS Plasticity Through the Extracellular Matrix

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Electrophysiology of Dendritic Spines: Information Processing, Dynamic Compartmentalization, and Synaptic Plasticity

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Activity-dependent extracellular proteolytic cascade cleaves the ECM component brevican to promote structural plasticity

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Enhancement of GluN2B Subunit-Containing NMDA Receptor Underlies Serotonergic Regulation of Long-Term Potentiation after Critical Period in the Rat Visual Cortex

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Age-related upregulation of perineuronal nets on inferior collicular cells that project to the cochlear nucleus

Almassri, L. S., Ohl, A. P., Iafrate, M. C., Wade, A. D., Tokar, N. J., Mafi, A. M., Beebe, N. L., Young, J. W., & Mellott, J. G. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1271008 · Cited by 3

Localized mRNAs and protein synthesis in cortical layer 1

Spanò, T., Nassim-Assir, B., Kaulich, E., Tushev, G., Fürst, N., Will, H., Marić, L., Ciirdaeva, E., & Schuman, E. M. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117687 · Cited by 3

Perineuronal Nets in the Superior Olivary Complex

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Cpeb1 remodels cell type–specific translational program to promote fear extinction

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Alteration of perineuronal nets and parvalbumin interneurons in prefrontal cortex and hippocampus, and correlation with blood corticosterone in activity-based anorexia model mice

Nguyen, H. D., Miyazaki, H., Kawai, H., Wang, Z., Sakamoto, S., Takaki, M., & Oohashi, T. (2025) · Neuroscience Research · doi:10.1016/j.neures.2025.104922 · Cited by 2

Structural underspinnings of functional plasticity in rodent visual cortex

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Layer- and region-specific distribution of chondroitinase-resistant, lectin-binding extracellular matrix structures in the mouse somatosensory cortex and hippocampus

Ueno, H., Kitano, E., Mori, S., Takahashi, Y., Murakami, S., Wani, K., Matsumoto, Y., Okamoto, M., & Ishihara, T. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.08.017 · Cited by 1

Neuromuscular Junction (NMJ): Synaptic Basal Lamina ☆

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Sinapsien ikuspegi modernoa: zelulaz kanpoko matrizearen funtzioa konexio neuronalean

Nuñez-delMoral, A., & Erdozain, A. M. (2018) · EKAIA Euskal Herriko Unibertsitateko Zientzi eta Teknologi Aldizkaria · doi:10.1387/ekaia.19676 · Cited by 1

The Role of Perineuronal Nets in Regulating Barrel Cortex Physiology

Chu, P. (2015) · CUNY Academic Works (City University of New York) · Cited by 1

Recycling as a mechanism for extracellular matrix remodeling at the synapse

Dankovich, T. M. (2021) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-8998 · Cited by 1

Focal Clusters of Peri-Synaptic Matrix Contribute to Activity-Dependent Plasticity and MemoryPreprint

Chelini, G., Mirzapourdelavar, H., Durning, P. T., Baidoe‐Ansah, D., O'Donovan, S. M., Klengel, T., Balasco, L., Berciu, C., Boyer‐Boiteau, A., Smith, R. A., et al. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4512954 · Cited by 1

Imaging in Neurology Research II: Exploring Plasticity and Cognitive Networks by In Vivo MRI

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Perineuronal nets set the strength of thalamic recruitment of interneurons in the adult visual cortexPreprint

Faini, G., Aguirre, A., Landi, S., Pizzorusso, T., Ratto, G. M., Deleuze, C., & Bacci, A. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/374587

Novel CS-6 Cluster Microenvironments: The Effect of Fear Conditioning Influencing the Number, Morphology, and Synaptic Activation of CS-6 Clusters

Khan, M. (2018) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Removal of the extracellular matrix biases auditory cortical layer dynamics towards supragranular frequency integrationPreprint

El‐Tabbal, M., Niekisch, H., Henschke, J. U., Budinger, E., Frischknecht, R., Deliano, M., & Happel, M. F. K. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.04.076224

Physiological Roles of Perineuronal Nets in Cerebellar Functions

Hirono, M. (2021) · Contemporary clinical neuroscience · doi:10.1007/978-3-030-75817-2_8

Faculty Opinions recommendation of Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain.

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Activity-dependent turnover of the Perineural Extracellular Matrix

Petersen, G. C. (2024) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-10429

Motor cortex perineuronal net modulation improves motor function in a Parkinson’s disease mouse modelPreprint

Benacom, D., Chataing, C., Prochiantz, A., & Nardo, A. A. D. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.31.596849

Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticityPreprint

Singh, J. B., Perelló‐Amorós, B., Schneeberg, J., Seidenbecher, C. I., Fejtová, A., Dityatev, A. E., & Frischknecht, R. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.28.620597

Additional file 1 of Shank3 deletion in PV neurons is associated with abnormal behaviors and neuronal functions that are rescued by increasing GABAergic signaling

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COUNTERING AGE-ASSOCIATED ALTERATIONS IN OLIGODENDROCYTE-DERIVED EXTRACELLULAR MATRIX REJUVENATES COGNITIONPreprint

Philp, A. R., Remesal, L., Pratt, K. J. B., Maynard, J. C., Sahota, S., Aghayev, T., Bieri, G., Chu, R., Avillion, G., Sucharov, J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.03.702938

Synaptic changes upon removal of extracellular perineuronal nets in adult mouse visual cortex

Faini, G. (2017) · theses.fr (ABES) · doi:10.70675/7b38d504z7edfz47dezbf9az0a8668ae448a

Contrôle du réseau périneuronal par l’activité des interneurones à décharge rapide exprimant la parvalbumine

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Etude du rôle du Syndécan à la jonction neuromusculaire de Caenorhabditis elegans

Vachon, C. (2020) · theses.fr (ABES) · doi:10.70675/4f34af1dzeed7z426dzbab2zb1e21a201491

Implication du tPA cérébral dans la régulation des comportements et le remodelage des perineuronal nets

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Control of thalamocortical synaptic transmission onto parvalbumin interneurons by perineuronal nets in adult primary visual cortex

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Rôle des astrocytes dans la période critique de la plasticité visuelle

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Sexually dimorphic organization of extracellular matrix and perineuronal nets in the prairie vole (Microtus ochrogaster) social brain

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Experience-dependent modulation of extracellular matrix integrity supports perceptual skill learning and memory

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Perisynaptic Chondroitin Sulfate Proteoglycans Restrict Structural Plasticity in an Integrin-Dependent Manner

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Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood

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Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science · doi:10.1126/science.1072699 · Cited by 1,679

Freeing the Brain from the Perineuronal Net

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PERSPECTIVES

(2009)