Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Mederacke, Ingmar, Hsu, Christine C., Troeger, Juliane S., Huebener, Peter, Mu, Xueru, Dapito, Dianne H., Pradere, Jean-Philippe, Schwabe, Robert F.·2013·Nature Communications

Cited by (1,001)

Items 801–900 of 1,001

  1. IGF2-NR4A2 Signaling Regulates Macrophage Subtypes to Attenuate Liver Cirrhosis
    Lichao Yao, Xue Hu, Mengqin Yuan, Qiuling Zhang, Pingji Liu, Lian Yang, Kai Dai, Yingan Jiang · 2023 · Journal of Clinical and Translational Hepatology
  2. Identification of antrodin B from Antrodia camphorata as a new anti‐hepatofibrotic compound using a rapid cell screening method and biological evaluation
    Yan Geng, Jing Wang, Qing Sun, Minfeng Xie, Zhen‐Ming Lu, Hongyu Xu, Jin‐Song Shi, Zhenghong Xu · 2015 · Hepatology Research
  3. Induction and contribution of beta platelet‐derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice
    Peri Kocabayoglu, David Y. Zhang, Kensuke Kojima, Yujin Hoshida, Scott L. Friedman · 2015 · Liver International
  4. The Mechanisms of HSC Activation and Epigenetic Regulation of HSCs Phenotypes
    Agata Page, Derek A. Mann, Jelena Mann · 2014 · Current Pathobiology Reports
  5. Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury
    Zhang, Rong, Kikuchi, Alexander T., Nakao, Toshimasa, Russell, Jacquelyn O., Preziosi, Morgan E., Poddar, Minakshi, Singh, Sucha, Bell, Aaron W., England, Steven G., Monga, Satdarshan P. · 2019 · Gene Expression
  6. Identification and functional validation of miR-190b-5p and miR-296-3p as novel therapeutic attenuators of liver fibrosis
    Jovana Markovic, Ruomeng Li, Rajendra Khanal, Qi Peng, Selina Möbus, Qinggong Yuan, Bastian Engel, Richard Taubert, Florian W. R. Vondran, Heike Bantel et al. · 2024 · Journal of Hepatology
  7. A comprehensive molecular atlas of the mesenchymal cell types in the mouse liver
    Riikka S. Pietilä, Guillem Genové, Giuseppe Mocci, Yuyang Miao, Jianping Liu, Stefanos Leptidis, Francesca Del Gaudio, Martin Uhrbom, Elisa Vázquez-Liébanas, Sonja Gustafsson et al. · 2025 · EMBO Reports
  8. Heterogeneity and plasticity of cancer-associated fibroblasts
    Sneha Pramod, Hagar Lavon, Ruth Scherz‐Shouval, Mara H. Sherman · 2026 · Nature Cancer
  9. Loss of pericyte smoothened activity in mice with genetic deficiency of leptin
    Guanhua Xie, Marzena Swiderska‐Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory Alexander Michelotti, Richard T. Premont, Anna Mae Diehl · 2017 · BMC Cell Biology
  10. Mesenchymal Stem/Stromal Cells in Progressive Fibrogenic Involvement and Anti-Fibrosis Therapeutic Properties
    Chenghai Li, Bin Wang · 2022 · Frontiers in Cell and Developmental Biology
  11. Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways
    Hangxing Yu, Zhe Feng, Wei Lin, Kang Yang, Ruiqi Liu, Jiaqi Li, Xinyue Liu, Ming Pei, Hongtao Yang · 2022 · Aging and Disease
  12. Early‐immediate gene Egr1 is associated with TGFβ1 regulation of epigenetic reader Bromodomain‐containing protein 4 via the canonical Smad3 signaling in hepatic stellate cells in vitro and in vivo
    Haimeng Tian, Feifan Xu, Feifei Zhao, Nachuan Pan, Sidan Lu, Xin Jia, Yajun Zhou · 2022 · The FASEB Journal
  13. Fucoxanthin exert dose-dependent antifibrotic and anti-inflammatory effects on CCl4-induced liver fibrosis
    Vasilii N. Slautin, Dmitry Yu. Grebnev, I. Yu. Maklakova, Sergey Vladimirovich Sazonov · 2023 · Journal of Natural Medicines
  14. The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis
    Yuwen Zhu, Aoqi Kang, Yameng Kuai, Yan Guo, Xiulian Miao, Li Zhu, Ming Kong, Nan Li · 2023 · Cell Death and Disease
  15. p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
    Marcos F. Fondevila, Eva Nóvoa, María J. Gonzalez-Rellan, Uxia Fernandez, Violeta Heras, Begoña Porteiro, Tamara Parracho, Valentina Dorta, Cristina Riobello, Natália da Silva Lima et al. · 2024 · Cell Reports Medicine
  16. A long‐acting FGF21 attenuates metabolic dysfunction‐associated steatohepatitis‐related fibrosis by modulating NR4A1‐mediated Ly6C phenotypic switch in macrophages
    Yue Ru Ji, Yiliang Duan, Yuanyuan Li, Qingzhou Lu, Dingkang Liu, Yifan Yang, Ruilong Chang, Tian Jing, Wenbing Yao, Jun Yin et al. · 2024 · British Journal of Pharmacology
  17. Overcoming Resistance to Immune Checkpoint Blockade in Liver Cancer with Combination Therapy: Stronger Together?
    Wiebke Werner, Maria Kuzminskaya, Isabella Lurje, Frank Tacke, Linda Hammerich · 2024 · Seminars in Liver Disease
  18. Immune Checkpoints and the Immunology of Liver Fibrosis
    Ioannis Tsomidis, Argyro Voumvouraki, Elias Kouroumalis · 2025 · Livers
  19. Pericytes in Metastasis
    Zalitha Pieterse, Devbarna Sinha, Pritinder Kaur · 2019 · Advances in experimental medicine and biology
  20. Recapitulating human tissue damage, repair, and fibrosis with human pluripotent stem cell-derived organoids
    Maria F. Sobral-Reyes, Dario Ruben Lemos · 2019 · Stem Cells
  21. Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation
    Qing‐Hong Du, Chu-Jun Zhang, Weihong Li, Yan Mu, Ya Xu, Scott Lowe, Lin Han, Xue Yu, Shuyan Wang, Yu Li et al. · 2020 · World Journal of Gastroenterology
  22. Liver fibrosis is driven by protease‐activated receptor‐1 expressed by hepatic stellate cells in experimental chronic liver injury
    Lauren G. Poole, Asmita Pant, Holly M. Cline-Fedewa, Kurt J. Williams, Bryan Lloyd Copple, Joseph S. Palumbo, James P. Luyendyk · 2020 · Research and Practice in Thrombosis and Haemostasis
  23. The Role of Mesenchymal Stromal Cells in Tissue Repair and Fibrosis
    Yoshikiyo Akasaka · 2021 · Advances in Wound Care
  24. Pulmonary Arterial Hypertension and Consecutive Right Heart Failure Lead to Liver Fibrosis
    Florian Hamberger, Ekaterina Legchenko, Philippe Chouvarine, Young‐Seon Mederacke, Richard Taubert, Martin Meier, Danny David Jonigk, Georg Hansmann, Ingmar Mederacke · 2022 · Frontiers in Cardiovascular Medicine
  25. Rat bone marrow mesenchymal stem cells (BMSCs) inhibit liver fibrosis by activating GSK3β and inhibiting the Wnt3a/β-catenin pathway
    Zhaoguo Liu, Song Zhou, Ya Zhang, Ming Zhao · 2022 · Infectious Agents and Cancer
  26. Hepatic Myofibroblasts: A Heterogeneous and Redox-Modulated Cell Population in Liver Fibrogenesis
    Claudia Bocca, Francesca Protopapa, Beatrice Foglia, Marina Maggiora, Stefania Cannito, Maurizio Parola, Erica Novo · 2022 · Antioxidants
  27. Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses
    Aidan Brougham‐Cook, Hannah Kimmel, Chase P. Monckton, Daniel Owen, Salman R. Khetani, Gregory H. Underhill · 2022 · APL Bioengineering
  28. Hydronidone induces apoptosis in activated hepatic stellate cells through endoplasmic reticulum stress‐associated mitochondrial apoptotic pathway
    Zhongshang Sun, Yuecheng Guo, Xianjun Xu, Cui Lan Zhou, Xin Luo, Zhenyang Shen, Bo Shen, Junjun Wang, Jingyi Lu, Qingqing Zhang et al. · 2024 · Journal of Gastroenterology and Hepatology
  29. Epigenetic regulation of liver fibrosis
    Agata Page, Derek A. Mann · 2015 · Clinics and Research in Hepatology and Gastroenterology
  30. Hepatic Stellate Cell‐Derived Microvesicles Prevent Hepatocytes from Injury Induced by APAP/H2O2
    Renwei Huang, Qunwen Pan, Xiaotang Ma, Yan Wang, Yaolong Liang, Bingyan Dai, Xiaorong Liao, Mingyi Li, Huilai Miao · 2016 · Stem Cells International
  31. Role of stellate cells in hepatic echinococcosis in cattle
    Hasan Atmaca, Aycan Nuriye Gazyağci, Osman Safa Terzi, Tuğçe Sümer · 2019 · Journal of Parasitic Diseases
  32. Stromal and Immune Drivers of Hepatocarcinogenesis
    Antonio Saviano, Natascha Roehlen, Alessia Virzì, Armando Andres Roca Suarez, Yujin Hoshida, Joachim Lupberger, Thomas F. Baumert · 2019 · Molecular and translational medicine
  33. Mechanistic insights into the effects of SREBP1c on hepatic stellate cell and liver fibrosis
    Shengyan Su, Haimeng Tian, Xin Jia, Xiaofei Zhu, Juanjuan Wu, Yali Zhang, Yuanyuan Chen, Ziqiang Li, Yajun Zhou · 2020 · Journal of Cellular and Molecular Medicine
  34. β-Arrestin2 is increased in liver fibrosis in humans and rodents
    Robert Schierwagen, Peter Dietrich, Sabine Klein, Frank Erhard Uschner, Cristina Ortiz, Olaf Tyc, Sandra Torres, Claus Hellerbrand, Tilman Sauerbruch, Jonel Trebicka · 2020 · Proceedings of the National Academy of Sciences
  35. Cellular senescence in human liver under normal aging and cancer
    Karpova, Alla, Li, Xiang, Peng, Chien-Wei, Gallant, Kelsey L., Rapp, Daniel R., Alligood, Daniel M., Houston, Andrew J., Park, Alex, Targino da Costa, Andre Luiz N., Chou, Wen-hung et al. · 2026 · Cell Genomics
  36. CCL24 and Fibrosis: A Narrative Review of Existing Evidence and Mechanisms
    Raanan Greenman, Chris J. Weston · 2025 · Cells
  37. Estrogen receptor 1 signaling in hepatic stellate cells designates resistance to liver fibrosis
    Tianhao Li, Gang Wang, Han Zhao, Fuhai Liu, Zhangyuzi Deng, Dingbao Chen, Xin Zhou, Ying Cao, Wei Fu, Haoyue Zhang et al. · 2025 · Cell Discovery
  38. MFAP4 Deficiency Attenuates Liver Fibrosis by Regulating Hepatic Stellate Cell Fate Through Inhibition of the FAK/PI3K/NFκB Signaling Pathway
    Linxiang Liu, Bimin Li, Yue Zhang, Yuan Nie, Wang Zhang, Peng Chen, Chenkai Huang, Xuan Zhu · 2025 · Cellular and Molecular Gastroenterology and Hepatology
  39. Decoding the CHI3L1/IL-13Rα2 signaling nexus in MASH-fibrosis pathogenesis
    Qianqian Zheng, Yanli Cao, Xuefeng Jiang, Xiao Wang, Xiaonan Wang, Yan He, Wenmeng Ma, Hao Wu, Yuxuan Jiang, TONGXIN WANG et al. · 2025 · Science Advances
  40. Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis
    Bichen Zhang, Kalina Lapenta, Qi Wang, Jin Hyun Nam, Dongjun Chung, Marie E. Robert, Michael H. Nathanson, Xiaoyong Yang · 2021 · Journal of Biological Chemistry
  41. Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit?
    Georgios Neokosmidis, Εvangelos Cholongitas, Κωνσταντίνος Τζιόμαλος · 2021 · World Journal of Gastroenterology
  42. Stanniocalcin 1 is a serum biomarker and potential therapeutic target for HBV ‐associated liver fibrosis
    Kristy Kwan‐Shuen Chan, Tsz‐Chun Hon, K.K. Au, Hiu‐Lam Choi, Danny K.-H. Wong, Albert C. Y. Chan, Man‐Fung Yuen, Ching‐Lung Lai, Regina Cheuk‐Lam Lo · 2022 · The Journal of Pathology
  43. Notoginsenoside R1 targets PPAR-γ to inhibit hepatic stellate cell activation and ameliorates liver fibrosis
    Cheng Guo, Linying Lai, Boyu Ma, Qian Huang, Zhirong Wang · 2024 · Experimental Cell Research
  44. Progress, application and challenges of liver organoids
    Chen Sang, Jian Lin, Shuyi Ji, Qiang Gao · 2024 · Clinical Cancer Bulletin
  45. Hepatic stellate cells in zone 1 engage in capillarization rather than myofibroblast formation in murine liver fibrosis
    Muhammad Ashfaq Khan, Julian Fischer, Leon Harrer, Fabian Schwiering, Dieter Groneberg, Andreas Friebe · 2024 · Scientific Reports
  46. Predicting and managing liver fibrosis in biliary atresia
    Iiris Nyholm, Maria Hukkinen, Mikko P. Pakarinen · 2024 · Seminars in Pediatric Surgery
  47. Hepatic stellate cell-specific miR-214 expression alleviates liver fibrosis without boosting steatosis and inflammation
    Fangqing Zhao, Xuan Niu, Ge Song, Lijie Wang, Yiming Fu, Shuwen Li, Xinxin Gu, Qingkun Wang, Jiao Luo · 2025 · Journal of Translational Medicine
  48. Selective LOXL2 inhibition: potent antifibrotic effects in ongoing fibrosis and fibrosis regression
    Fernando Magdaleno, Jonel Trebicka · 2017 · Gut
  49. Polaprezinc inhibits liver fibrosis and proliferation in hepatocellular carcinoma
    Jun Ye, Zhengsen Zhang, Liang Wei Zhu, Minfang Lu, Yan Li, Jingjing Zhou, Xinliang Lu, Qin Du · 2017 · Molecular Medicine Reports
  50. Modeling Liver Biology and the Tissue Response to Injury in Bioprinted Human Liver Tissues
    Kelsey N. Retting, Dwayne Carter, Candace Crogan‐Grundy, Chirag B. Khatiwala, Leah M. Norona, Elizabeth H. Paffenroth, Umesh Hanumegowda, Alice P. Chen, Lisa A. Hazelwood, Lois D. Lehman‐McKeeman et al. · 2018 · Applied In Vitro Toxicology
  51. High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
    Yuanyuan Guo, Chen Xu, Yan Fang, Caie Wang, Na Gao, Qiang Wen, Hai–Ling Qiao · 2019 · Molecular Carcinogenesis
  52. Characterization of Burn Eschar Pericytes
    Alexander Evdokiou, Onur Kanisicak, Stephanie Gierek, Amanda Barry, Malina J. Ivey, Xiang Zhang, Richard J. Bodnar, Latha Satish · 2020 · Journal of Clinical Medicine
  53. Tyrosine kinase inhibitor neratinib attenuates liver fibrosis by targeting activated hepatic stellate cells
    Yong Joo Park, Hyoung-Tae An, Jong Sung Park, Ogyi Park, Alexander J. Duh, Kwangmeyung Kim, Kyu Hyuck Chung, Kang Choon Lee, Yumin Oh, Seulki Lee · 2020 · Scientific Reports
  54. Crocin inhibits the activation of mouse hepatic stellate cells via the lnc-LFAR1/MTF-1/GDNF pathway
    Ji Xuan, Dongmei Zhu, Zhengyuan Cheng, Yuping Qiu, Mei Shao, Ya Yang, Qi Zhai, Fangyu Wang, Feng Qin · 2020 · Cell Cycle
  55. Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation
    Heming Huang, Xiaoru Zhou, Yanjun Liu, Shijie Fan, Liping Liao, Jing Li Huang, Cuicui Shi, Liang Yu, Jin-Jin Pen, Cheng Luo et al. · 2021 · Molecular Medicine Reports
  56. Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway
    Rong Kang, Wen Tian, Wei Cao, Yang Sun, Huinan Zhang, Ying-Da Feng, Chen Li, Zezhi Li, Xiaoqiang Li · 2021 · Chinese Journal of Natural Medicines
  57. Emerging therapeutic potential of adeno-associated virus-mediated gene therapy in liver fibrosis
    Fangtian Bu, Pengcheng Jia, Yan Yu Zhu, Yaru Yang, Hongwu Meng, Yihui Bi, Cheng Huang, Jun Li · 2022 · Molecular Therapy — Methods & Clinical Development
  58. Human umbilical cord-derived mesenchymal stromal cells alleviate liver cirrhosis through the Hippo/YAP/Id1 pathway and macrophage-dependent mechanism
    Lichao Yao, Xue Hu, Mengqin Yuan, Pingji Liu, Qiuling Zhang, Zheng Wang, Ping Chen, Zhiyu Xiong, Lun Wu, Kai Dai et al. · 2023 · International Immunopharmacology
  59. Pentoxifylline inhibits liver fibrosis via hedgehog signaling pathway
    Hui Li, Juan Hua, Chunxia Guo, Weixian Wang, Baoju Wang, Dongliang Yang, Ping Wei, Yinping Lu · 2016 · Journal of Huazhong University of Science and Technology [Medical Sciences]
  60. Myofibroblasts Derived from Hepatic Progenitor Cells Create the Tumor Microenvironment
    Sayaka Sekiya, Shizuka Miura, Kanae Matsuda‐Ito, Atsushi Suzuki · 2016 · Stem Cell Reports
  61. Crosstalk between Epigenetic Modulations in Valproic Acid Deactivated Hepatic Stellate Cells: An Integrated Protein and miRNA Profiling Study
    Peng Lü, Min Yan, Li He, Jing Li, Yuhua Ji, Juling Ji · 2018 · International Journal of Biological Sciences
  62. Unravelling fibrosis using single-cell transcriptomics
    Ross Dobie, Neil Cowan Henderson · 2019 · Current Opinion in Pharmacology
  63. Cellular and molecular effects of silymarin on the transdifferentiation processes of LX-2 cells and its connection with lipid metabolism
    Caio Mateus da Silva, Gustavo Duarte Ferrari, Luciane C. Alberici, Osmar Malaspina, Karen C. M. Moraes · 2020 · Molecular and Cellular Biochemistry
  64. Role of Oxidative and Nitrosative Stress in Hepatic Fibrosis
    T.T. Thuy le, Tuong Thi Van Thuy, Hoang Hai, Norifumi Kawada · 2017 · Elsevier eBooks
  65. Gastrointestinal cancer: molecular pathogenesis and targeted therapy
    Yang Jin, Xiaobo He, Yanfeng Wu · 2025 · Molecular Biomedicine
  66. Advances in pharmacological interventions for hepatic fibrosis: from pathogenic mechanisms to novel therapeutic targets
    Weiqin Zhang, Ting Shao, Caiyan Wang, Shaogui Wang, Lin An · 2026 · Annals of Medicine
  67. Inflammatory pathways and cholangiocarcinoma risk mechanisms and prevention
    Massimiliano Cadamuro, Mario Strazzabosco · 2022 · Advances in cancer research
  68. Identifying a distinct fibrosis subset of NAFLD via molecular profiling and the involvement of profibrotic macrophages
    Weiwei He, Yinxiang Huang, Xiulin Shi, Qingxuan Wang, Menghua Wu, Han Li, Qiuhong Liu, Xiaofang Zhang, Caoxin Huang, Xuejun Li · 2023 · Journal of Translational Medicine
  69. Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis
    Haushabhau S. Pagire, Suvarna H. Pagire, Byung-kwan Jeong, Won‐Il Choi, Chang Joo Oh, Chae Won Lim, Minhee Kim, Jihyeon Yoon, Seong Soon Kim, Myung Ae Bae et al. · 2024 · Nature Communications
  70. Knockdown of Hyaluronan synthase 2 suppresses liver fibrosis in mice via induction of transcriptomic changes similar to 4MU treatment
    Noreen Halimani, Mikhail V. Nesterchuk, Alexandra A. Tsitrina, Marat S. Sabirov, Irina N. Andreichenko, Nataliya O. Dashenkova, Elizaveta Petrova, А. М. Куликов, Timofei S. Zatsepin, Roman A. Romanov et al. · 2024 · Scientific Reports
  71. Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma
    Silvia Affò, Laura Sererols-Viñas, Gemma Garcia‐Vicién, Massimiliano Cadamuro, Sanjukta Chakraborty, Alphonse Eugene Sirica · 2024 · American Journal Of Pathology
  72. The desulfinylation enzyme sulfiredoxin-1 attenuates HSC activation and liver fibrosis by modulating the PTPN12-NLRP3 axis
    Jong-Won Kim, Hung‐Chun Tung, Mengyun Ke, Pengfei Xu, Xinran Cai, Yue Xi, Meishu Xu, Songrong Ren, Yixian Huang, Amit Bhowmik et al. · 2024 · Hepatology
  73. Jiawei Qi Gong Wan improves liver fibrosis and inflammation in PCOS mice via the Akt2-FoxO1 and YAP/TAZ signaling pathways
    Jie Li, Ruqun Zheng, Yingyan Shen, Yuxuan Zhuo, Lingjing Lu, Jinlong Song, Jing Li, Maohua Lai, He Zhu, Min Hu et al. · 2024 · Phytomedicine
  74. Hepatic Stellate Cells Functional Heterogeneity in Liver Cancer
    Laura Sererols-Viñas, Gemma Garcia‐Vicién, Paloma Ruiz-Blázquez, Ting‐Fang Lee, Youngmin A. Lee, Ester Gonzalez‐Sanchez, Javier Vaquero, Anna Moles, Aveline A. Filliol, Silvia Affò · 2025 · Seminars in Liver Disease
  75. Expression of mediators of purinergic signaling in human liver cell lines
    Jessica R. Goree, Élise G. Lavoie, Michel Fausther, Jonathan A. Dranoff · 2014 · Purinergic Signalling
  76. Methods and Strategies for Lineage Tracing of Mesenchymal Progenitor Cells
    R. Wilder Scott, T. Michael Underhill · 2016 · Methods in molecular biology
  77. Hepatic cirrhosis and recovery as reflected by Raman spectroscopy: information revealed by statistical analysis might lead to a prognostic biomarker
    Kerstin Galler, Esther Fröhlich, Andreas Kortgen, Michael W Bauer, Jürgen Popp, Ute Neugebauer · 2016 · Analytical and Bioanalytical Chemistry
  78. Stem Cell-based Therapy Strategy for Hepatic Fibrosis by Targeting Intrahepatic Cells
    Yaxin Deng, Bin Xia, Zhongmin Chen, Fuping Wang, Yonggang Lv, Guobao Chen · 2021 · Stem Cell Reviews and Reports
  79. Transcriptome analysis reveals the molecular mechanism of Yiqi Rougan decoction in reducing CCl4-induced liver fibrosis in rats
    Yu Xiong, Jinyuan Hu, Chen Xuan, Jiayu Tian, Kaiyue Tan, Zhiwei Chen, Yan Luo, Xuqin Du, Junxiong Cheng, Lanyue Zhang et al. · 2021 · Chinese Medicine
  80. Emergence of highly profibrotic and proinflammatory Lrat + Fbln2 + HSC subpopulation in alcoholic hepatitis
    Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat Elbaradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li et al. · 2022 · Hepatology
  81. Suv39h1 contributes to activation of hepatic stellate cells in non-alcoholic fatty liver disease by enabling anaerobic glycolysis
    Xiaoyan Wu, Yuzhou Shen, Yufei Meng, Jinsi Chen, Yongchen Zhang, Sheng Zeng, Huihui Xu · 2024 · Life Sciences
  82. Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β
    Joey A. Muns, Erik Schooten, Rychon D. J. van Dasselaar, Yvet E. Noordman, Kevin Adamzek, Arthur C. Eibergen, Sebas D. Pronk, Sagel Cali, Niels J. Sijbrandi, Eugen Merkul et al. · 2024 · European Journal of Nuclear Medicine and Molecular Imaging
  83. DGAT1-deficiency affects the cellular distribution of hepatic retinoid and attenuates the progression of CCl4-induced liver fibrosis.
    Jason J. Yuen, Seung‐Ah Lee, Hongfeng Jiang, Pierre‐Jacques Brun, William S. Blaner · 2015 · Europe PMC (PubMed Central)
  84. Assessment of Liver Fibrotic Insults In Vitro
    Luís Perea, Mar Coll, Pau Sancho‐Bru · 2014 · Methods in molecular biology
  85. Hepatic perivascular mesenchymal stem cells with myogenic properties
    Sudheer Shenoy P, Bipasha Bose · 2017 · Journal of Tissue Engineering and Regenerative Medicine
  86. Emerging Roles of Perivascular Mesenchymal Stem Cells in Synovial Joint Inflammation
    Yosra Bedoui, Grégorie Lebeau, Xavier Guillot, Farouk Dargai, Pascale Guiraud, Jim W. Neal, Stéphane Ralandison, Philippe Gasque · 2020 · Journal of Neuroimmune Pharmacology
  87. Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location
    Mladen I. Yovchev, Fadi Luc Jaber, Zhonglei Lu, Shachi Patel, Joseph D. Locker, Leslie E. Rogler, John W. Murray, Marius Sudol, Mariana D. Dabeva, Liang Zhu et al. · 2016 · Scientific Reports
  88. MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H+ Transporting V1 Subunit C1
    Fei Jing, Yan Geng, Xinyi Xu, Hongyu Xu, Jin‐Song Shi, Zhenghong Xu · 2019 · International Journal of Molecular Sciences
  89. Hemostatic alterations in metabolic dysfunction-associated steatotic liver disease (MASLD) and their link to venous thromboembolism (VTE)
    David E González-Mendoza, Francisco Fernández-Nogueira, Misael Uribe, Norberto Carlos Chávez-Tapia, Natalia Nuño‐Lámbarri · 2025 · Thrombosis Research
  90. Innate immunity of bile and cholangiocytes in primary biliary cholangitis
    Ran Chen, Yan Sun, Ying Hu, Wenlin Tai · 2025 · Frontiers in Immunology
  91. Hepatic stellate cell-intrinsic role of SOCS1 in controlling hepatic fibrogenic response and the pro-inflammatory macrophage compartment during liver fibrosis
    Rajani Kandhi, Mehdi Yeganeh, Akihiko Yoshimura, Alfredo Menéndez, Sheela Ramanathan, Subburaj Ilangumaran · 2023 · Frontiers in Immunology
  92. The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production
    Zhiqian Kang, Chenqi Wang, Fang Shao, Hao Deng, Sun Yanyan, Zhengrong Ren, Wei Yan Zhang, Zhi Ding, Junfeng Zhang, Yuhui Zang · 2024 · Journal of Biological Chemistry
  93. Inflammation and Immunity in Liver Neoplasms: Implications for Future Therapeutic Strategies
    Jieun Kim, Ekihiro Seki · 2024 · Molecular Cancer Therapeutics
  94. Advances, challenges and future applications of liver organoids in experimental regenerative medicine
    Da Gong, Jiaye Mo, Mei Zhai, Fulin Zhou, Guo‐Cai Wang, Shaohua Ma, Xiaoyong Dai, Xuesong Deng · 2025 · Frontiers in Medicine
  95. Identification of a robust promoter in mouse and human hepatocytes by in vivo biopanning of a barcoded AAV library
    Jonas Becker, Claire Domenger, Pervinder K. Choksi, Chiara Krämer, Conradin Baumgartl, Olena Maiakovska, Jae-Jun Kim, Jonas Weinmann, Georg Huber, Florian Schmidt et al. · 2025 · Molecular Therapy
  96. A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis
    Xiaobo Wang, Mary P. Moore, Hongxue Shi, Yang Xiao, Jiayu Zhang, Lanuza A.P. Faccioli, Zhiping Hu, Shareef Khalid, Danish Saleheen, Dwayne G. Stupack et al. · 2025 · Nature Metabolism
  97. Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Promotes Hepatic Stellate Cells Migration via Canonical NF-κB/MMP9 Pathway
    Mingcui Xu, Feng Zhang, Aixiu Wang, Chen Wang, Yu Qing Cao, Ming Zhang, Mingming Zhang, Min Su, Xiaoping Zou, Guifang Xu et al. · 2016 · PLoS ONE
  98. Substance P promotes hepatic stellate cell proliferation and activation via the TGF-β1/Smad-3 signaling pathway
    Lei Peng, Xiaoqing Jia, Jianjian Zhao, Ruibing Cui, Ming Yan · 2017 · Toxicology and Applied Pharmacology
  99. Cxcl10 deficiency attenuates renal interstitial fibrosis through regulating epithelial-to-mesenchymal transition
    Jie Gao, Lingling Wu, Yinghua Zhao, Quan Hong, Zhe Feng, Xiangmei Chen · 2021 · Experimental Cell Research
  100. Lipidomics Indicates the Hepatotoxicity Effects of EtOAc Extract of Rhizoma Paridis
    Chaofeng Li, Mingshuang Wang, Tingting Fu, Zhiqi Li, Yang Chen, Tao He, Dan Feng, Zhaoyi Wang, Qiqi Fan, Meilin Chen et al. · 2022 · Frontiers in Pharmacology