The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Adaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation
Open accessAbstract
Adaptive introgression can provide novel genetic variation to fuel rapid evolutionary responses, though it may be counterbalanced by potential for detrimental disruption of the recipient genomic background. We examine the extent and impact of recent introgression of a strongly selected insecticide-resistance mutation (Vgsc-1014F) located within one of two exceptionally large genomic islands of divergence separating the Anopheles gambiae species pair. Here we show that transfer of the Vgsc mutation results in homogenization of the entire genomic island region (~1.5% of the genome) between species. Despite this massive disruption, introgression is clearly adaptive with a dramatic rise in frequency of Vgsc-1014F and no discernable impact on subsequent reproductive isolation between species. Our results show (1) how resilience of genomes to massive introgression can permit rapid adaptive response to anthropogenic selection and (2) that even extreme prominence of genomic islands of divergence can be an unreliable indicator of importance in speciation. Highly divergent genomic islands segregate between a species pair of the mosquito, Anopheles gambiae. Here Clarkson et al. show that loss of one of the largest islands, driven by adaptive introgression of an insecticide-resistance mutation, had no impact on reproductive isolation.
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Cites
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A Polytene Chromosome Analysis of the Anopheles gambiae Species Complex
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Self-citationMolecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa
Torre, A. D., Fanello, C., Akogbeto, M., Dossou‐yovo, J., Favia, G., Petrarca, V., & Coluzzi, M. (2001) · Insect Molecular Biology · doi:10.1046/j.1365-2583.2001.00235.x · Cited by 316
On the distribution and genetic differentiation of Anopheles gambiae s.s. molecular forms
della Torre, A., Tu, Z., & Petrarca, V. (2005) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2005.02.006 · Cited by 244
The molecular forms of Anopheles gambiae: a phenotypic perspective
Lehmann, T., & Diabate, A. (2008) · Infection, Genetics and Evolution · doi:10.1016/j.meegid.2008.06.003 · Cited by 177
Centromere-proximal differentiation and speciation in Anopheles gambiae
Stump, A. D., Fitzpatrick, M. C., Lobo, N. F., Traoré, S., Sagnon, N., Costantini, C., Collins, F. H., & Besansky, N. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508161102 · Cited by 103
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Cited by
Mallet, J., Besansky, N., & Hahn, M. W. (2016) · BioEssays · doi:10.1002/bies.201500149 · Cited by 586
Mapping trends in insecticide resistance phenotypes in African malaria vectors
Hancock, P. A., Hendriks, C. J. M., Tangena, J.-A., Gibson, H., Hemingway, J., Coleman, M., Gething, P. W., Cameron, E., Bhatt, S., & Moyes, C. L. (2020) · PLOS Biology · doi:10.1371/journal.pbio.3000633 · Cited by 201
Mattah, P. A. D., Futagbi, G., Amekudzi, L. K., Mattah, M. M., de Souza, D. K., Kartey-Attipoe, W. D., Bimi, L., & Wilson, M. D. (2017) · Parasites & Vectors · doi:10.1186/s13071-016-1941-3 · Cited by 136
Bradley, J., Ogouyèmi-Hounto, A., Cornélie, S., Fassinou, J., de Tove, Y. S. S., Adéothy, A. A., Tokponnon, F. T., Makoutode, P., Adechoubou, A., Legba, T., et al. (2017) · Malaria Journal · doi:10.1186/s12936-017-1873-1 · Cited by 53
Self-citationTennessen, J. A., Ingham, V. A., Toé, K. H., Guelbéogo, W. M., Sagnon, N., Kuzma, R., Ranson, H., & Neafsey, D. E. (2021) · Molecular Ecology · doi:10.1111/mec.15756 · Cited by 41
Metadata
- Authors
- Clarkson, C. S., Weetman, D., Essandoh, J., Yawson, A. E., Maslen, G., Manske, M., Field, S. G., Webster, M., Antão, T., MacInnis, B., Kwiatkowski, D., & Donnelly, M. J.
- Venue
- Nature Communications
- Published
- 2014-06-25
- Volume
- 5
- Issue
- 1
- Pages
- 4248-4248
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2046310373
- Cited by
- 178
- References
- 8
- FWCI
- 19.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
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