Biological interpretation of genome-wide association studies using predicted gene functions
Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja +10 more·2015·Nature Communications
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- GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWASAnselm Hoppmann, Pascal Schlosser, Rolf Backofen, Ekkehart U. Lausch, Anna Köttgen · 2016 · PLoS ONE
- Common shared genetic variation behind decreased risk of breast cancer in celiac diseaseEmilio Ugalde‐Morales, Jingmei Li, Keith Humphreys, Jonas Filip Ludvigsson, Haomin Yang, Per N Hall, Kamila Czene · 2017 · Scientific Reports
- Integrative analysis of genome-wide association study and common meQTLs for exploring the effects of DNA methylation on the development of neuroticismShuang Zhao, Zhigang Liu · 2020 · Journal of Affective Disorders
- Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapyLars C. Steggink, Hink Boer, Coby Meijer, Joop D. Lefrandt, Leon W.M.M. Terstappen, Rudolf S.N. Fehrmann, Jourik A. Gietema · 2020 · The Pharmacogenomics Journal
- Identifying genes targeted by disease-associated non-coding SNPs with a protein knowledge graphWytze J. Vlietstra, Rein Vos, Erik M. van Mulligen, Guido W Jenster, Jan A. Kors · 2022 · PLoS ONE
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- Using mouse genetics to understand human skeletal diseaseScott E. Youlten, Paul A. J. Baldock · 2019 · Bone
- Leveraging eQTLs to identify individual-level tissue of interest for a complex traitArunabha Majumdar, Claudia Giambartolomei, Na Cai, Tanushree Haldar, Tommer Schwarz, Michael J. Gandal, Jonathan Flint C, Bogdan Paşaniuc · 2021 · PLoS Computational Biology
- Genetic Linkage MappingAtsuko Imai‐Okazaki, Jürg Ott · 2018 · Encyclopedia of Life Sciences
- GWAS defines pathogenic signaling pathways and prioritizes drug targets for IgA nephropathyKrzysztof Kiryluk, Elena Sánchez, Shu‐Feng Zhou, Francesca Zanoni, Lili Liu, Nikol Mladkova, Atlas Khan, Maddalena Marasà, Jun Y. Zhang, Olivia Balderes et al. · 2021 · medRxiv
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- Modeling the genomic architecture of adiposity and anthropometrics across the lifespanChristopher H. Arehart, Meng Hsuan Lin, Raine A Gibson, Heather D. Anderson, Aquilante CL, Kelsey L. Arbogast, Christopher H. Arehart, Ian M. Brooks, Tonya M. Brunetti, Judith Brutus-Lestin et al. · 2025 · Nature Communications
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- Research Techniques Made Simple: Using Genome-Wide Association Studies to Understand Complex Cutaneous DisordersLam C. Tsoi, Matthew T. Patrick, James T. Elder · 2018 · Journal of Investigative Dermatology
- From GWASs toward Mechanistic Understanding with Case Studies in Dermatogenetics.S. Shen, M. K. Sobczyk, L. Paternoster, Sara J. Brown · 2024 · Journal of Investigative Dermatology
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- Rapporteur summaries of plenary, symposia, and oral sessions from the XXIIIrd World Congress of Psychiatric Genetics Meeting in Toronto, Canada, 16–20 October 2015Gwyneth C. Zai, Bonnie Alberry, Janine Arloth, Zsófia Bánlaki, Cristina B. Bares, Erik Boot, Caroline Camilo, Kartikay Chadha, Qi Chen, Christopher B. Cole et al. · 2016 · Psychiatric Genetics
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- A unifying statistical framework to discover disease genes from GWASsJustin N.J. McManus, Robert J. Lovelett, Daniel Lowengrub, Sarah Christensen · 2023 · Cell Genomics
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