LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Choi, Insup, Kim, Beomsue, Byun, Ji-Won, Baik, Sung Hoon, Huh, Yun Hyun, Kim, Jong-Hyeon, Mook-Jung, Inhee, Song, Woo Keun +7 more·2015·Nature Communications

Cited by (112)

Items 101–112 of 112

  1. Neuroinflammation and Parkinson’s Disease: Understanding the Inflammatory Process Induced by Chronic Peripheral Injection of LPS in LRRK2 G2019S KI Mice in Correlation with Age
    Anuroopa Dinesh · 2019
  2. Environmental toxicant exposure and Parkinson’s disease: LRRK2 and inflammatory processes
    Zachary Dwyer · 2019
  3. [Henock-Schönlein purpura and glomerulonephritis in children].
    O Pavkovčeková, Tischler, Ivan Jurkovič, Miroslav Mydlík · 1971 · PubMed
  4. LRRK2 Gly2019Ser Mutation Promotes Autophagy, ER Stress and Neuroinflammation via Interacting With THBS1/TGF-β1 in Parkinson's Disease
    Longping Yao, Shizhong Zhang · 2022 · SSRN Electronic Journal
  5. A role for LRRK2 and Neuroinflammatory Processes in Multi-Hit Toxicant Models of Parkinson’s Disease
    Chris Rudyk · 2018
  6. Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
    Zachary A. Gaertner, Cameron Oram, Amanda K. Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel A. Dombeck, Loukia Parisiadou, Jean-Francois Poulin, Rajeshwar B. Awatramani · 2025 · eLife
  7. Generation of Leucine-Rich Repeat Kinase 2 (LRRK2) Knockout Neuroblastoma Cells SH-SY5Y by CRISPR/Cas9-Mediated Genome Editing
    Hui-Lan Jong, Kit‐San Yuen, Dong‐Yan Jin, Susan Ling Ling Hoe, Aini Ideris, Chee‐Hong Tan, Sau-Kuen Lam, Yang Mooi Lim, Soon‐Keng Cheong · 2025 · Biochemical Genetics
  8. Additional file 1 of A novel microbial and hepatic biotransformation-integrated network pharmacology strategy explores the therapeutic mechanisms of bioactive herbal products in neurological diseases: the effects of Astragaloside IV on intracerebral hemorrhage as an example
    Hu, En, Li, Zhilin, Teng Li, Yang, Xueping, Ding, Ruoqi, Haoying Jiang, Hong Su, Cheng, Menghan, Yu, Zhe, Haigang Li et al. · 2023 · Figshare
  9. Additional file 1 of Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice
    Li, Dan, Yu, Shu-fang, Lin, Lin, Guo, Jie-ru, Huang, Si-mei, Wu, Xi-lin, Hanlin You, Cheng, Xiao-juan, Zhang, Qiu-yang, Zeng, Yu-qi et al. · 2024 · Figshare
  10. Mutation-Driven Remodeling of the LRRK2 Kinase Free-Energy Landscape and Its Consequences for Conformational Transitions and Inhibitor Binding Affinity
    Rajesh Ghosh, K. Bhanja, Niladri Patra · 2026 · Journal of Chemical Information and Modeling
  11. At the Crossroads of Synapses and Signaling: The Role of LRRK2 in Neuronal Communication
    Angela Di Iacovo, Chiara D’Agostino, Giulia Casoli, Tiziana Romanazzi, Elena Bossi, Cristina Roseti · 2026 · Cellular and Molecular Neurobiology
  12. Alzheimer’s genetic risk factor CASS4 controls microglial focal adhesion biology and amyloidosis
    Walsh, Adeline E., Davis, Benjamin A., Samuels, Joshua D., Mills, William A., Thanos, Jessica M., Johnson, Alexis M., Moore, Katelyn A., Puchalski, Michael A., Steacy, Eric J., Wendell, Benjamin W. et al. · 2026 · Journal of Experimental Medicine