The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Minke whale genome and aquatic adaptation in cetaceans
Open accessAbstract
Jung-Hyun Lee, Jong Bhak and their colleagues report the whole-genome sequencing and de novo assembly of a male minke whale genome, as well as the genome sequences of three additional minke whales, a fin whale, a bottlenose dolphin and a finless porpoise. Their comparative analysis across cetaceans provides insights into adaptation to an aquatic lifestyle. The shift from terrestrial to aquatic life by whales was a substantial evolutionary event. Here we report the whole-genome sequencing and de novo assembly of the minke whale genome, as well as the whole-genome sequences of three minke whales, a fin whale, a bottlenose dolphin and a finless porpoise. Our comparative genomic analysis identified an expansion in the whale lineage of gene families associated with stress-responsive proteins and anaerobic metabolism, whereas gene families related to body hair and sensory receptors were contracted. Our analysis also identified whale-specific mutations in genes encoding antioxidants and enzymes controlling blood pressure and salt concentration. Overall the whale-genome sequences exhibited distinct features that are associated with the physiological and morphological changes needed for life in an aquatic environment, marked by resistance to physiological stresses caused by a lack of oxygen, increased amounts of reactive oxygen species and high salt levels.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Guindon, S., Dufayard, J.-F., Lefort, V., Anisimova, M., Hordijk, W., & Gascuel, O. (2010) · Systematic Biology · doi:10.1093/sysbio/syq010 · Cited by 18,376
Trapnell, C., Williams, B. A., Pertea, G., Mortazavi, A., Kwan, G., van Baren, M. J., Salzberg, S. L., Wold, B. J., & Pachter, L. (2010) · Nature Biotechnology · doi:10.1038/nbt.1621 · Cited by 15,556
A method and server for predicting damaging missense mutations.
Adzhubei, I. A., Schmidt, S., Peshkin, L., Ramensky, V. E., Gerasimova, A., Bork, P., Kondrashov, A. S., & Sunyaev, S. R. (2010) · Nature Methods · doi:10.1038/nmeth0410-248 · Cited by 13,194
Statistical significance for genomewide studies
Storey, J. D., & Tibshirani, R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1530509100 · Cited by 9,692
Tandem repeats finder: a program to analyze DNA sequences
Benson, G. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.2.573 · Cited by 9,374
<tt>BLAT</tt> —The <tt>BLAST</tt> -Like Alignment Tool
Kent, W. J. (2002) · Genome Research · doi:10.1101/gr.229202 · Cited by 8,480
Inference of human population history from individual whole-genome sequences
Li, H., & Durbin, R. (2011) · Nature · doi:10.1038/nature10231 · Cited by 2,590
The sequence and de novo assembly of the giant panda genome
Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., et al. (2010) · Nature · doi:10.1038/nature08696 · Cited by 1,180
Self-citationA high-resolution map of human evolutionary constraint using 29 mammals
Broad Institute Sequencing Platform and Whole Genome Assembly Team, Lindblad-Toh, K., Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, Genome Institute at Washington University, Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Washietl, S., Kheradpour, P., et al. (2011) · Nature · doi:10.1038/nature10530 · Cited by 1,108
The yak genome and adaptation to life at high altitude
Qiu, Q., Zhang, G., Ma, T., Qian, W., Wang, J., Ye, Z., Cao, C., Hu, Q., Kim, J., Larkin, D. M., et al. (2012) · Nature Genetics · doi:10.1038/ng.2343 · Cited by 983
Self-citation
Cited by
The UCSC Genome Browser database: 2015 update
Rosenbloom, K. R., Armstrong, J., Barber, G. P., Casper, J., Clawson, H., Diekhans, M., Dreszer, T. R., Fujita, P. A., Guruvadoo, L., Haeussler, M., et al. (2015) · Nucleic Acids Research · doi:10.1093/nar/gku1177 · Cited by 874
Enhancer Evolution across 20 Mammalian Species
Villar, D., Berthelot, C., Aldridge, S., Rayner, T. F., Lukk, M., Pignatelli, M., Park, T. J., Deaville, R., Erichsen, J. T., Jasinska, A. J., et al. (2015) · Cell · doi:10.1016/j.cell.2015.01.006 · Cited by 825
Insights into the evolution of longevity from the bowhead whale genome
Keane, M., Semeiks, J., Webb, A. E., Li, Y. I., Quesada, V., Craig, T., Madsen, L. B., van Dam, S., Brawand, D., Marques, P. I., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2014.12.008 · Cited by 375
Self-citationViruses are a dominant driver of protein adaptation in mammals
Enard, D., Cai, L., Gwennap, C., & Petrov, D. A. (2016) · eLife · doi:10.7554/elife.12469 · Cited by 361
The Genome 10K Project: A Way Forward
Koepfli, K.-P., Paten, B., Scientists, T. G. 1. C. O., & O’Brien, S. J. (2015) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-090414-014900 · Cited by 311
Self-citation
Metadata
- Authors
- Yim, H.-S., Cho, Y. S., Guang, X., Kang, S. G., Jeong, J.-Y., Cha, S.-S., Oh, H.-M., Lee, J.-H., Yang, E. C., Kwon, K. K., Kim, Y. J., Kim, T. W., Kim, W., Jeon, J. H., Kim, S.-J., Choi, D. H., Jho, S., Kim, H.-M., Ko, J., Kim, H., Shin, Y.-A., Jung, H.-J., Zheng, Y., Wang, Z., Chen, Y., Chen, M., Jiang, A., Li, E., Zhang, S., Hou, H., Kim, T. H., Yu, L., Liu, S., Ahn, K., Cooper, J., Park, S.-G., Hong, C. P., Jin, W., Kim, H.-S., Park, C., Lee, K., Chun, S., Morin, P. A., O'Brien, S. J., Lee, H., Kimura, J., Moon, D. Y., Manica, A., Edwards, J., Kim, B. C., Kim, S., Wang, J., Bhak, J., Lee, H. S., & Lee, J.-H.
- Venue
- Nature Genetics
- Published
- 2013-11-24
- Volume
- 46
- Issue
- 1
- Pages
- 88-92
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2085313067
- Cited by
- 285
- References
- 12
- FWCI
- 20.72
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Minke whale genome and aquatic adaptation in cetaceans. https://app.cochat.ai/papers/10.1038/ng.2835
- The paper
- Yim, H.-S., Cho, Y. S., Guang, X., Kang, S. G., Jeong, J.-Y., Cha, S.-S., Oh, H.-M., Lee, J.-H., Yang, E. C., Kwon, K. K., Kim, Y. J., Kim, T. W., Kim, W., Jeon, J. H., Kim, S.-J., Choi, D. H., Jho, S., Kim, H.-M., Ko, J., . . . Lee, J.-H. (2014). Minke whale genome and aquatic adaptation in cetaceans. Nature Genetics. https://doi.org/10.1038/ng.2835
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
